List of works - Gregers Jungersen

A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-104:01, SLA-204:01, and SLA-3*04:01.

scientific article published on 14 November 2015

A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ⁺ CMI responses protects against a genital infection in minipigs

scientific article published on 13 August 2015

A review of the human vs. porcine female genital tract and associated immune system in the perspective of using minipigs as a model of human genital Chlamydia infection

scientific article

Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

scientific article published on 15 February 2008

Analysis of repeated tests for interferon-gamma (IFN-gamma) response and faecal excretion for diagnosis of subclinical paratuberculosis in Danish cattle

scientific article

Animal Models for Influenza A Virus Infection Incorporating the Involvement of Innate Host Defenses: Enhanced Translational Value of the Porcine Model

scientific article published on 01 December 2018

Ascaridia galli infection influences the development of both humoral and cell-mediated immunity after Newcastle Disease vaccination in chickens.

scientific article published on 21 November 2013

Ascaris suum infection negatively affects the response to a Mycoplasma hyopneumoniae vaccination and subsequent challenge infection in pigs.

scientific article

Association between milk antibody and interferon-gamma responses in cattle from Mycobacterium avium subsp. paratuberculosis infected herds

article

Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70.

scientific article

Cell-mediated and humoral immune responses after immunization of calves with a recombinant multiantigenic Mycobacterium avium subsp. paratuberculosis subunit vaccine at different ages

scientific article published on 6 February 2013

Cell-mediated immune responses differentiate infections with Brucella suis from Yersinia enterocolitica serotype O:9 in pigs.

scientific article published on 9 January 2007

Characterisation of an ELISA detecting immunoglobulin G to Mycobacterium avium subsp. paratuberculosis in bovine colostrum

scientific article

Characterization of cytological changes, IgA, IgG and IL-8 levels and pH value in the vagina of prepubertal and sexually mature Ellegaard Göttingen minipigs during an estrous cycle

scientific article published on 19 January 2016

Characterization of the long-term immune response to vaccination against Mycobacterium avium subsp. paratuberculosis in Danish dairy cows

scientific article published on 3 December 2011

Co-incubation with IL-18 potentiates antigen-specific IFN-γ response in a whole-blood stimulation assay for measurement of cell-mediated immune responses in pigs experimentally infected with Lawsonia intracellularis

scientific article published on 21 September 2010

Comparison of parasite-specific immunoglobulin levels in two chicken lines during sustained infection with Ascaridia galli.

scientific article published on 7 August 2012

Correlation of antigen-specific IFN-γ responses of fresh blood samples from Mycobacterium avium subsp. paratuberculosis infected heifers with responses of day-old samples co-cultured with IL-12 or anti-IL-10 antibodies

scientific article published on 17 April 2012

Current Status of Veterinary Vaccines

scientific article (publication date: July 2007)

Cytokine gene expression profiles in chicken spleen and intestinal tissues during Ascaridia galli infection

scientific article

Development of patent Ascaris suum infections in pigs following intravenous administration of larvae hatched in vitro

article

Development, characterization and diagnostic application of a monoclonal antibody specific for a proteinase K resistant Lawsonia intracellularis antigen

scientific article published on 29 December 2004

Differential expression of genes encoding CD30L and P-selectin in cattle with Johne's disease: Progress toward a diagnostic gene expression signature

article

Editorial: "Humanized" Large Animal Cancer Models: Accelerating Time and Effectiveness of Clinical Trials

scientific article published on 27 August 2019

Establishing the pig as a large animal model for vaccine development against human cancer

scientific article

Evaluation of a novel enzyme-linked immunosorbent assay for serological diagnosis of porcine proliferative enteropathy

scientific article published on 01 August 2005

Expanding specificity of class I restricted CD8+ T cells for viral epitopes following multiple inoculations of swine with a human adenovirus vectored foot-and-mouth disease virus (FMDV) vaccine.

scientific article published on 27 July 2016

Experimental Ascaris suum infection in the pig: protective memory response after three immunizations and effect of intestinal adult worm population.

scientific article published on December 1999

Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Response Mediated by FOXP3+ T Cells and Immunoregulatory Molecules.

scientific article published on 7 June 2018

Genital Infiltrations of CD4 and CD8 T Lymphocytes, IgA and IgG Plasma Cells and Intra-Mucosal Lymphoid Follicles Associate With Protection Against Genital Infection in Minipigs Intramuscularly Immunized With UV-Inactivated Bacteria Adjuvanted With C

scientific article published on 08 February 2019

INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges

scientific article published on 01 December 2018

Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs

scientific article

Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-10401 and SLA-20401.

scientific article

Identification of swine influenza virus epitopes and analysis of multiple specificities expressed by cytotoxic T cell subsets

scientific article

Immune gene expression in the spleen of chickens experimentally infected with Ascaridia galli.

scientific article published on 14 January 2015

Immune markers and correlates of protection for vaccine induced immune responses ⬇️

scientific article published on May 30, 2012

Improved Culture Medium (TiKa) for Mycobacterium avium Subspecies Paratuberculosis (MAP) Matches qPCR Sensitivity and Reveals Significant Proportions of Non-viable MAP in Lymphoid Tissue of Vaccinated MAP Challenged Animals

scientific article published on January 2016

Increasing the ex vivo antigen-specific IFN-γ production in subpopulations of T cells and NKp46+ cells by anti-CD28, anti-CD49d and recombinant IL-12 costimulation in cattle vaccinated with recombinant proteins from Mycobacterium avium subspecies pa

scientific article published on 27 August 2013

Induction of foot-and-mouth disease virus-specific cytotoxic T cell killing by vaccination

scientific article

Interpretation of the gamma interferon test for diagnosis of subclinical paratuberculosis in cattle.

scientific article

Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies

scientific article published on 14 April 2019

Intramuscular Priming and Intranasal Boosting Induce Strong Genital Immunity Through Secretory IgA in Minipigs Infected with Chlamydia trachomatis

scientific article

Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus.

scientific article published on 09 February 2017

Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells

scientific article

Longitudinal study of interferon-gamma, serum antibody and milk antibody responses in cattle infected with Mycobacterium avium subsp. paratuberculosis

article

Low antigen dose formulated in CAF09 adjuvant Favours a cytotoxic T-cell response following intraperitoneal immunization in Göttingen minipigs

scientific article published on 5 September 2017

No protection in chickens immunized by the oral or intra-muscular immunization route with Ascaridia galli soluble antigen

scientific article published in January 2013

Novel Adjuvants and Immunomodulators for Veterinary Vaccines.

scientific article published on January 2016

Novel antigens for detection of cell mediated immune responses to Mycobacterium avium subsp. paratuberculosis infection in cattle

article

Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research

scientific article published on 01 December 2018

Optimization of the agar-gel method for isolation of migrating Ascaris suum larvae from the liver and lungs of pigs

scientific article

Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV-2 strains

scientific article

Primary infection protects pigs against re-infection with Lawsonia intracellularis in experimental challenge studies.

scientific article

Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses

scientific article published on 19 March 2018

Repeated examination of natural sapovirus infections in pig litters raised under experimental conditions.

scientific article

Review of Mycobacterium avium subsp. paratuberculosis antigen candidates with diagnostic potential

scientific article published on 16 March 2011

Revisiting the IFN-γ release assay: Whole blood or PBMC cultures? - And other factors of influence

scientific article published on 9 April 2016

Sequence-Based Genotyping of Expressed Swine Leukocyte Antigen Class I Alleles by Next-Generation Sequencing Reveal Novel Swine Leukocyte Antigen Class I Haplotypes and Alleles in Belgian, Danish, and Kenyan Fattening Pigs and Göttingen Minipigs

scientific article

Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and identification of commonly occurring haplotypes using sequence specific low and high resolution primers.

scientific article published on 23 October 2014

Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

scientific article published in PLoS ONE

The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs

scientific article published on 05 July 2019

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

scientific article published on 23 August 2017

Transfer of maternal immunity to piglets is involved in early protection against Mycoplasma hyosynoviae infection.

scientific article published on 5 December 2016

Use of a novel serum ELISA method and the tonsil-carrier state for evaluation of Mycoplasma hyosynoviae distributions in pig herds with or without clinical arthritis

scientific article published on 19 September 2005

Use of the johnin PPD interferon-gamma assay in control of bovine paratuberculosis ⬇️

scientific article published on May 7, 2011

Vaccination of pigs with attenuated Lawsonia intracellularis induced acute phase protein responses and primed cell-mediated immunity without reduction in bacterial shedding after challenge

scientific article published on 11 November 2014

List of works by Gregers Jungersen

A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01.

A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ⁺ CMI responses protects against a genital infection in minipigs

A review of the human vs. porcine female genital tract and associated immune system in the perspective of using minipigs as a model of human genital Chlamydia infection

Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

Analysis of repeated tests for interferon-gamma (IFN-gamma) response and faecal excretion for diagnosis of subclinical paratuberculosis in Danish cattle

Animal Models for Influenza A Virus Infection Incorporating the Involvement of Innate Host Defenses: Enhanced Translational Value of the Porcine Model

Ascaridia galli infection influences the development of both humoral and cell-mediated immunity after Newcastle Disease vaccination in chickens.

Ascaris suum infection negatively affects the response to a Mycoplasma hyopneumoniae vaccination and subsequent challenge infection in pigs.

Association between milk antibody and interferon-gamma responses in cattle from Mycobacterium avium subsp. paratuberculosis infected herds

Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70.

Cell-mediated and humoral immune responses after immunization of calves with a recombinant multiantigenic Mycobacterium avium subsp. paratuberculosis subunit vaccine at different ages

Cell-mediated immune responses differentiate infections with Brucella suis from Yersinia enterocolitica serotype O:9 in pigs.

Characterisation of an ELISA detecting immunoglobulin G to Mycobacterium avium subsp. paratuberculosis in bovine colostrum

Characterization of cytological changes, IgA, IgG and IL-8 levels and pH value in the vagina of prepubertal and sexually mature Ellegaard Göttingen minipigs during an estrous cycle

Characterization of the long-term immune response to vaccination against Mycobacterium avium subsp. paratuberculosis in Danish dairy cows

Co-incubation with IL-18 potentiates antigen-specific IFN-γ response in a whole-blood stimulation assay for measurement of cell-mediated immune responses in pigs experimentally infected with Lawsonia intracellularis

Comparison of parasite-specific immunoglobulin levels in two chicken lines during sustained infection with Ascaridia galli.

Correlation of antigen-specific IFN-γ responses of fresh blood samples from Mycobacterium avium subsp. paratuberculosis infected heifers with responses of day-old samples co-cultured with IL-12 or anti-IL-10 antibodies

Current Status of Veterinary Vaccines

Cytokine gene expression profiles in chicken spleen and intestinal tissues during Ascaridia galli infection

Development of patent Ascaris suum infections in pigs following intravenous administration of larvae hatched in vitro

Development, characterization and diagnostic application of a monoclonal antibody specific for a proteinase K resistant Lawsonia intracellularis antigen

Differential expression of genes encoding CD30L and P-selectin in cattle with Johne's disease: Progress toward a diagnostic gene expression signature

Editorial: "Humanized" Large Animal Cancer Models: Accelerating Time and Effectiveness of Clinical Trials

Establishing the pig as a large animal model for vaccine development against human cancer

Evaluation of a novel enzyme-linked immunosorbent assay for serological diagnosis of porcine proliferative enteropathy

Expanding specificity of class I restricted CD8+ T cells for viral epitopes following multiple inoculations of swine with a human adenovirus vectored foot-and-mouth disease virus (FMDV) vaccine.

Experimental Ascaris suum infection in the pig: protective memory response after three immunizations and effect of intestinal adult worm population.

Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Response Mediated by FOXP3+ T Cells and Immunoregulatory Molecules.

Genital Infiltrations of CD4 and CD8 T Lymphocytes, IgA and IgG Plasma Cells and Intra-Mucosal Lymphoid Follicles Associate With Protection Against Genital Infection in Minipigs Intramuscularly Immunized With UV-Inactivated Bacteria Adjuvanted With C

INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges

Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs

Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401.

Identification of swine influenza virus epitopes and analysis of multiple specificities expressed by cytotoxic T cell subsets

Immune gene expression in the spleen of chickens experimentally infected with Ascaridia galli.

Immune markers and correlates of protection for vaccine induced immune responses ⬇️

Improved Culture Medium (TiKa) for Mycobacterium avium Subspecies Paratuberculosis (MAP) Matches qPCR Sensitivity and Reveals Significant Proportions of Non-viable MAP in Lymphoid Tissue of Vaccinated MAP Challenged Animals

Increasing the ex vivo antigen-specific IFN-γ production in subpopulations of T cells and NKp46+ cells by anti-CD28, anti-CD49d and recombinant IL-12 costimulation in cattle vaccinated with recombinant proteins from Mycobacterium avium subspecies pa

Induction of foot-and-mouth disease virus-specific cytotoxic T cell killing by vaccination

Interpretation of the gamma interferon test for diagnosis of subclinical paratuberculosis in cattle.

Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies

Intramuscular Priming and Intranasal Boosting Induce Strong Genital Immunity Through Secretory IgA in Minipigs Infected with Chlamydia trachomatis

Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus.

Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells

Longitudinal study of interferon-gamma, serum antibody and milk antibody responses in cattle infected with Mycobacterium avium subsp. paratuberculosis

Low antigen dose formulated in CAF09 adjuvant Favours a cytotoxic T-cell response following intraperitoneal immunization in Göttingen minipigs

No protection in chickens immunized by the oral or intra-muscular immunization route with Ascaridia galli soluble antigen

Novel Adjuvants and Immunomodulators for Veterinary Vaccines.

Novel antigens for detection of cell mediated immune responses to Mycobacterium avium subsp. paratuberculosis infection in cattle

Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research

Optimization of the agar-gel method for isolation of migrating Ascaris suum larvae from the liver and lungs of pigs

Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV-2 strains

Primary infection protects pigs against re-infection with Lawsonia intracellularis in experimental challenge studies.

Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses

Repeated examination of natural sapovirus infections in pig litters raised under experimental conditions.

Review of Mycobacterium avium subsp. paratuberculosis antigen candidates with diagnostic potential

Revisiting the IFN-γ release assay: Whole blood or PBMC cultures? - And other factors of influence

Sequence-Based Genotyping of Expressed Swine Leukocyte Antigen Class I Alleles by Next-Generation Sequencing Reveal Novel Swine Leukocyte Antigen Class I Haplotypes and Alleles in Belgian, Danish, and Kenyan Fattening Pigs and Göttingen Minipigs

Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and identification of commonly occurring haplotypes using sequence specific low and high resolution primers.

Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

Transfer of maternal immunity to piglets is involved in early protection against Mycoplasma hyosynoviae infection.

Use of a novel serum ELISA method and the tonsil-carrier state for evaluation of Mycoplasma hyosynoviae distributions in pig herds with or without clinical arthritis

Use of the johnin PPD interferon-gamma assay in control of bovine paratuberculosis ⬇️

Vaccination of pigs with attenuated Lawsonia intracellularis induced acute phase protein responses and primed cell-mediated immunity without reduction in bacterial shedding after challenge

A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-104:01, SLA-204:01, and SLA-3*04:01.

Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-10401 and SLA-20401.