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List of works by Brigitte Malgrange

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis

scientific article published on December 2015

A role for the canonical nuclear factor-κB pathway in coupling neurotrophin-induced differential survival of developing spiral ganglion neurons

scientific article

AAV2 vectors mediate efficient and sustained transduction of rat embryonic ventral mesencephalon.

scientific article published in August 2002

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

scientific article published on 18 December 2019

Activation of protein kinase CbetaI constitutes a new neurotrophic pathway for deafferented spiral ganglion neurons

scientific article published in October 2005

Adult neurogenesis and the diseased brain.

scientific article published on January 2009

Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation

scientific article

Astroglia-released factor shows similar effects as benzodiazepine inverse agonists

scientific article published on 01 November 1994

Astroglia-released factor with negative allosteric modulatory properties at the GABA A receptor

scientific article published on August 1996

Beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway.

scientific article published in January 2005

CDK2 is dispensable for adult hippocampal neurogenesis

scientific article published on 14 September 2007

Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis

scientific article published in December 1999

Caspase inhibitors prevent cisplatin-induced apoptosis of auditory sensory cells.

scientific article published in August 1998

Caspases, the enemy within, and their role in oxidative stress-induced apoptosis of inner ear sensory cells.

scientific article published in July 2004

Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous system

scientific article

Cdk6-dependent regulation of G(1) length controls adult neurogenesis

scientific article

Cell "circadian" cycle: new role for mammalian core clock genes

scientific article published on 16 March 2009

Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.

scientific article published in February 2018

Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells

scientific article published in October 2003

Cochlear afferent innervation development

scientific article published on 28 July 2015

Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling

scientific article published on 29 April 2015

Concise Review: Regeneration in Mammalian Cochlea Hair Cells: Help from Supporting Cells Transdifferentiation

scientific article published on 19 January 2017

Concise review: forkhead pathway in the control of adult neurogenesis

scientific article published on June 2014

Core cell cycle machinery is crucially involved in both life and death of post-mitotic neurons

scientific article published on 31 May 2020

Correction: Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

scientific article published on 10 March 2017

Cycling or not cycling: cell cycle regulatory molecules and adult neurogenesis

scientific article

Cytokine production by human thymic epithelial cells: control by the immune recognition of the neurohypophysial self-antigen.

scientific article

Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages

scientific article published on 24 April 2006

Developmental regulation of neuroligand-induced responses in cultured oligodendroglia.

scientific article published in April 1998

Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture

scientific article published in February 1997

Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects

scientific article published on 19 September 2016

Early identification of inner pillar cells during rat cochlear development

scientific article

Effect of neurotrophic factors on the inner ear: clinical implications.

scientific article published on March 1996

Effect of systemic nitroglycerin on CGRP and 5-HT afferents to rat caudal spinal trigeminal nucleus and its modulation by estrogen

scientific article

Effects of neurotrophins on early auditory neurones in cell culture

scientific article published in March 1996

Elongator controls cortical interneuron migration by regulating actomyosin dynamics

scientific article published on 27 September 2016

Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin

scientific article

Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

scientific article

EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions

Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells

scientific article

Expression patterns of miR-96, miR-182 and miR-183 in the development inner ear.

scientific article published in June 2009

Functional glycine receptors are expressed by postnatal nestin-positive neural stem/progenitor cells

scientific article

Gene transfer in inner ear cells: a challenging race

scientific article published on 28 June 2012

Generation of Isogenic Human iPS Cell Line Precisely Corrected by Genome Editing Using the CRISPR/Cas9 System

scientific article published on 10 June 2015

Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death.

scientific article published on 16 March 2018

Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10.

scientific article

Glycine triggers an intracellular calcium influx in oligodendrocyte progenitor cells which is mediated by the activation of both the ionotropic glycine receptor and Na+-dependent transporters

scientific article published on 01 June 2000

Hair cell progenitors: identification and regulatory genes

scientific article published on March 2010

Hair cell progenitors: identification and regulatory genes

article

Hearing preservation in cochlear implantation and drug treatment.

scientific article

Identification of factors that maintain mammalian outer hair cells in adult organ of Corti explants

scientific article

Image analysis of neuritic regeneration by adult rat dorsal root ganglion neurons in culture: quantification of the neurotoxicity of anticancer agents and of its prevention by nerve growth factor or basic fibroblast growth factor but not brain-deriv

scientific article

In Vitro Ototoxicity of aminoglycosides and platin derivatives. A semi-automatic assay for sensory hair cell damage in explanted rat organ of corti

scientific article published on 01 December 1998

In vitro and in vivo modulation of 5-hydroxytryptamine-, thyrotropin-releasing hormone- and calcitonin-gene related peptide-like immunoreactivities in adult rat sensory neurons

scientific article published in November 1992

Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex

scientific article

Mechanisms and Functional Significance of Stroke-Induced Neurogenesis

scientific article

Mechanisms of cell death in the injured auditory system: otoprotective strategies

scientific article

MicroRNA targeting of CoREST controls polarization of migrating cortical neurons

scientific article published in May 2014

MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5.

scientific article published on 16 September 2015

MicroRNAs tune cerebral cortical neurogenesis

scientific article

NGF, BDNF and NT-3 play unique roles in the in vitro development and patterning of innervation of the mammalian inner ear

scientific journal article

NOX3, a superoxide-generating NADPH oxidase of the inner ear

scientific article

NT-3 and/or BDNF therapy prevents loss of auditory neurons following loss of hair cells

scientific article published in March 1996

NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants

scientific article published on 01 July 1995

Neuronal Circuitries During Inner Ear Development

article

Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro

scientific article

New insights into peripherin expression in cochlear neurons.

scientific article published on 21 September 2007

Ototoxic drugs: difference in sensitivity between mice and guinea pigs

scientific article

Oxidative Stress in the Cochlea: An Update ⬇️

scientific article published on January 1, 2010

Period 2 regulates neural stem/progenitor cell proliferation in the adult hippocampus

scientific article

Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression

scientific article published on 17 January 2005

Pharmacological modulation of the bystander effect in the herpes simplex virus thymidine kinase/ganciclovir gene therapy system: effects of dibutyryl adenosine 3',5'-cyclic monophosphate, alpha-glycyrrhetinic acid, and cytosine arabinoside

scientific article published in July 2000

Pluripotent stem cell-derived cochlear cells: a challenge in constant progress

Preparation of a macroporous biodegradable polylactide implant for neuronal transplantation

scientific article

Proliferation of hippocampal progenitors relies on p27-dependent regulation of Cdk6 kinase activity.

scientific article

Proliferative generation of mammalian auditory hair cells in culture

scientific article published in March 2002

Protection of both auditory hair cells and auditory neurons from cisplatin induced damage.

scientific article published in March 1997

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity

scientific article published on 19 July 2019

Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti

scientific article published on 11 September 2009

Strategies to regenerate hair cells: identification of progenitors and critical genes.

scientific article published on 06 September 2007

Striatal PSA-NCAM(+) precursor cells from the newborn rat express functional glycine receptors

scientific article published in March 2004

Structure and development of cochlear afferent innervation in mammals

scientific article published on 13 July 2011

Substance P protects spiral ganglion neurons from apoptosis via PKC-Ca2+-MAPK/ERK pathways

scientific article published in October 2003

Supernumerary Outer Hair Cells Arise External to the Last Row of Sensory Cells in the Organ of Corti

scientific article published on 01 January 2001

Targeting cholesterol homeostasis to fight hearing loss: a new perspective

scientific article

The Yin and Yang of cell cycle progression and differentiation in the oligodendroglial lineage.

scientific article published on January 2006

The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

scientific article

The miR-183/ItgA3 axis is a key regulator of prosensory area during early inner ear development

scientific article published on 4 August 2017

The role of post-translational modifications in hearing and deafness

scientific article published on 4 May 2016

The ubiquitin-proteasome system in normal hearing and deafness

scientific article published in 2022

Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels

scientific article published on 12 May 2017

Transforming growth factor alpha treatment alters intracellular calcium levels in hair cells and protects them from ototoxic damage in vitro

scientific article published on July 1997

Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury.

scientific article published in January 1993

Untangling the functional potential of PSA-NCAM-expressing cells in CNS development and brain repair strategies

scientific article

Using human pluripotent stem cells to untangle neurodegenerative disease mechanisms

scientific article published on 26 October 2010

Vector-mediated delivery of bcl-2 prevents degeneration of auditory hair cells and neurons after injury

scientific article published on 2 November 2006

p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration

scientific article published on 27 September 2012

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