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List of works by Patrick P Michel

A simplified approach for efficient isolation of functional microglial cells: Application for modeling neuroinflammatory responses in vitro

scientific article published on 25 July 2016

Acceleration of conduction velocity linked to clustering of nodal components precedes myelination. ⬇️

scientific article

Activation of the mitogen-activated protein kinase (ERK(1/2)) signaling pathway by cyclic AMP potentiates the neuroprotective effect of the neurotransmitter noradrenaline on dopaminergic neurons

scientific article published in November 2002

Acylated and unacylated ghrelin confer neuroprotection to mesencephalic neurons

scientific article

Adenosine prevents the death of mesencephalic dopaminergic neurons by a mechanism that involves astrocytes

scientific article published in May 1999

Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

scientific article published in January 1997

Atypical parkinsonism in the Caribbean island of Guadeloupe: etiological role of the mitochondrial complex I inhibitor annonacin.

scientific article

Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model

scientific article (publication date: 2013)

Cannabidiol prevents LPS-induced microglial inflammation by inhibiting ROS/NF-κB-dependent signaling and glucose consumption

scientific article published on 24 October 2019

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

scholarly article

Ceramide induces apoptosis in cultured mesencephalic neurons

scientific article published in February 1996

Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons

scientific article published in October 1996

Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats

scientific article published on February 2003

Death of septal cholinergic neurons produced by chronic exposure to glutamate is prevented by the noncompetitive NMDA receptor/channel antagonist, MK-801: role of nerve growth factor and nitric oxide

scientific article published on April 1995

Differential activation of astrocytes and microglia during post-natal development of dopaminergic neuronal death in the weaver mouse

scientific article published in October 2003

Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon

scientific article

Dopaminergic neurons reduced to silence by oxidative stress: an early step in the death cascade in Parkinson's disease?

scientific article published on 25 April 2006

Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways

scientific article

Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

scientific article published in September 2003

Experimental evidence for a toxic etiology of tropical parkinsonism

scientific article published in January 2005

Flavaglines as potent anticancer and cytoprotective agents

scientific article published on 23 October 2012

Function and expression of the Bcl-x gene in the developing and adult nervous system.

scientific article published in October 1995

Glia protects neurons against extracellular human neuromelanin

scientific article published in January 2007

Granulocyte colony-stimulating factor is not protective against selective dopaminergic cell death in vitro.

scientific article published on 13 April 2005

Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease

scientific article

Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?

scientific article published in March 2001

KATP channel blockade protects midbrain dopamine neurons by repressing a glia-to-neuron signaling cascade that ultimately disrupts mitochondrial calcium homeostasis

scientific article published on 29 April 2010

Mechanisms of apoptosis in PC12 cells irreversibly differentiated with nerve growth factor and cyclic AMP.

scientific article published in March 1999

Methylxanthines and Ryanodine Receptor Channels ⬇️

scientific article published on January 1, 2011

Microglial glutamate release evoked by α-synuclein aggregates is prevented by dopamine

scientific article published on 05 November 2018

Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in Parkinson's disease.

scientific article published in October 1997

Modelling Parkinson-like neurodegeneration via osmotic minipump delivery of MPTP and probenecid

scientific article published on 16 September 2008

Modulation of dopamine uptake by nitric oxide in cultured mesencephalic neurons.

scientific article published on 3 January 2008

Molecular mechanisms of neuronal cell death: implications for nuclear factors responding to cAMP and phorbol esters

scientific article published on 01 September 2002

Morphological and molecular characterization of the response of differentiated PC12 cells to calcium stress

scientific article

Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases

scientific article published on 05 December 2019

Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+.

scientific article published on 20 April 2011

Neuroprotective and neurorestorative potential of xenon.

scientific article published on 7 April 2016

Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease.

scientific article

New 6-Aminoquinoxaline Derivatives with Neuroprotective Effect on Dopaminergic Neurons in Cellular and Animal Parkinson Disease Models.

scientific article published on 24 June 2016

No relevance to Parkinson's

scientific article published in Nature

Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels

scientific article

Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop.

scientific article published on 17 April 2018

Piperazine derivatives as iron chelators: a potential application in neurobiology

scientific article published on 26 October 2015

Potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium: selective toxicity of 1-methyl-4-(4'-acetamidophenyl)-pyridinium and 1-methyl-4-cyclohexylpyridinium for dopaminergic neurons in culture

scientific article

Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes

scientific article published in September 2003

Probenecid potentiates MPTP/MPP+ toxicity by interference with cellular energy metabolism

scientific article published on 8 July 2013

Proliferation of microglial cells induced by 1-methyl-4-phenylpyridinium in mesencephalic cultures results from an astrocyte-dependent mechanism: role of granulocyte macrophage colony-stimulating factor.

scientific article published on 31 August 2005

Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization.

scientific article published on 19 March 2009

Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside

scientific article published in October 1997

Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels

scientific article (publication date: 30 June 2004)

Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates

scientific article published on 25 July 2019

Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson's disease

scientific article published on 10 November 2015

S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization

scientific article published on 19 December 2018

Selective and non-selective trophic actions on central cholinergic and dopaminergic neurons in vitro

scientific article published in January 1990

Selective and nonselective protective effects of brain-derived neurotrophic factor for dopaminergic neurons in vitro

scientific article published in April 1993

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II.

scientific article published in February 1990

Selective destruction of cultured dopaminergic neurons from fetal rat mesencephalon by 1-methyl-4-phenylpyridinium: cytochemical and morphological evidence

scientific article published on 01 June 1988

Signaling Mechanisms in the Nitric Oxide Donor- and Amphetamine-Induced Dopamine Release in Mesencephalic Primary Cultured Neurons.

scientific article published on 21 September 2015

Sparing of orexin-A and orexin-B neurons in the hypothalamus and of orexin fibers in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated macaques

scientific article published on 18 October 2014

Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease.

scientific article published on 22 May 2013

Substance P, neurokinins A and B, and synthetic tachykinin peptides protect mesencephalic dopaminergic neurons in culture via an activity-dependent mechanism.

scientific article

Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson's Disease

scientific article published on 6 February 2016

Survival factors promote BDNF protein expression in mesencephalic dopaminergic neurons

scientific article published in March 1999

Survival promotion of mesencephalic dopaminergic neurons by depolarizing concentrations of K+ requires concurrent inactivation of NMDA or AMPA/kainate receptors

scientific article

Synergistic differentiation by chronic exposure to cyclic AMP and nerve growth factor renders rat phaeochromocytoma PC12 cells totally dependent upon trophic support for survival

scientific article published on 01 February 1995

The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations

scientific article

The glutamate antagonist, MK-801, does not prevent dopaminergic cell death induced by the 1-methyl-4-phenylpyridinium ion (MPP+) in rat dissociated mesencephalic cultures

scientific article published in December 1992

The iron-binding protein lactoferrin protects vulnerable dopamine neurons from degeneration by preserving mitochondrial calcium homeostasis.

scientific article published on 27 September 2013

The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy

scientific article

The neurotransmitter noradrenaline rescues septal cholinergic neurons in culture from degeneration caused by low-level oxidative stress.

scientific article published on 22 March 2005

The noble gas xenon provides protection and trophic stimulation to midbrain dopamine neurons

scientific article published on 11 April 2017

The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease

scholarly article

The phenotypic differentiation of locus ceruleus noradrenergic neurons mediated by brain-derived neurotrophic factor is enhanced by corticotropin releasing factor through the activation of a cAMP-dependent signaling pathway

scientific article published on 28 March 2006

The relationship between differentiation and survival in PC12 cells treated with cyclic adenosine monophosphate in the presence of epidermal growth factor or nerve growth factor

scientific article published in January 2001

The role of glial reaction and inflammation in Parkinson's disease.

scientific article

The sleep-modulating peptide orexin-B protects midbrain dopamine neurons from degeneration, alone or in cooperation with nicotine.

scientific article published on 31 December 2014

Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease

scientific article published on January 2013

Toxic effects of iron for cultured mesencephalic dopaminergic neurons derived from rat embryonic brains

scientific article published in July 1992

Toxic effects of potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium on cultured rat dopaminergic neurons

scientific article published on 01 February 1989

Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility

scientific article

Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture

scientific article published in August 1990

Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in Guadeloupe.

scientific article published on January 2002

Tyrosine hydroxylase mRNA expression by dopaminergic neurons in culture: effect of 1-methyl-4-phenylpyridinium treatment.

scientific article published on August 1991

Understanding Dopaminergic Cell Death Pathways in Parkinson Disease

scientific article published on May 2016

Xenon-mediated neuroprotection in response to sustained, low-level excitotoxic stress

scientific article published on 16 May 2016

[Neuronal death caused by apoptosis in Parkinson disease]

scientific article published on 01 September 1997

[Parkinson's disease: cell death mechanisms]

scientific article published on 01 January 2002

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