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List of works by Gabriele Missale

A meta-analysis of single HCV-untreated arm of studies evaluating outcomes after curative treatments of HCV-related hepatocellular carcinoma.

scientific article published on 6 January 2017

Activation of natural killer cells during acute infection with hepatitis C virus. ⬇️

scientific article

Acute phase HBV-specific T cell responses associated with HBV persistence after HBV/HCV coinfection.

scientific article published in April 2005

Antibody responses to hepatitis C virus hypervariable region 1: evidence for cross-reactivity and immune-mediated sequence variation

scientific article published in August 1999

Antiviral CD8-mediated responses in chronic HCV carriers with HBV superinfection

scientific article published on August 2004

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

article

Application of the Intermediate-Stage Subclassification to Patients With Untreated Hepatocellular Carcinoma

scientific article published on 5 January 2016

Are Anti-TNF-α Agents Safe for Treating Psoriasis in Hepatitis C Virus Patients with Advanced Liver Disease? Case Reports and Review of the Literature

scientific article published on 08 October 2015

Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

scientific article published on 7 February 2007

Combination of radiofrequency ablation and immunotherapy.

scientific article published on January 2008

Combined blockade of programmed death-1 and activation of CD137 increase responses of human liver T cells against HBV, but not HCV.

scientific article published on 25 August 2012

Comparative pathogenesis of HBV and HCV.

scientific article

Comparison between alcohol- and hepatitis C virus-related hepatocellular carcinoma: clinical presentation, treatment and outcome.

scientific article

Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: implications for vaccine development.

scientific article published in October 1999

Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen ⬇️

scientific article published on December 1, 1991

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target.

scientific article published on 6 June 2016

Determinants of alpha-fetoprotein levels in patients with hepatocellular carcinoma: implications for its clinical use.

scientific article published on 10 April 2014

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

scientific article (publication date: August 1996)

Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections.

scientific article published in January 1997

Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection

scientific article published in March 2007

Early intrahepatic CD8 responses in HBV pathogenesis: a new piece of the puzzle

scientific article published on 12 June 2006

Early kinetics of innate and adaptive immune responses during hepatitis B virus infection

scientific article published on 6 February 2009

Energy metabolism and cell motility defect in NK-cells from patients with hepatocellular carcinoma

scientific article published on 19 April 2020

Estimation of lead-time bias and its impact on the outcome of surveillance for the early diagnosis of hepatocellular carcinoma.

scientific article published on 6 April 2014

Etanercept in the treatment of psoriasis and psoriatic arthritis with concomitant hepatitis C virus infection: clinical and virological study in three patients

scientific article published in July 2011

Ex vivo characterization of tumor-derived melanoma antigen encoding gene-specific CD8+cells in patients with hepatocellular carcinoma

scientific article (publication date: 2004)

Expression of pERK and VEGFR-2 in advanced hepatocellular carcinoma and resistance to sorafenib treatment.

scientific article published on 22 January 2015

Focal adhesion kinase (FAK) mediates the induction of pro-oncogenic and fibrogenic phenotypes in hepatitis C virus (HCV)-infected cells

scientific article

Gene expression analysis during acute hepatitis C virus infection associates dendritic cell activation with viral clearance.

scientific article published on 8 October 2015

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts

scientific article

HCV-specific T-cell response in relation to viral kinetics and treatment outcome (DITTO-HCV project).

scientific article published on 3 July 2007

HLA and killer immunoglobulin-like receptor genes as outcome predictors of hepatitis C virus-related hepatocellular carcinoma

scientific article published on 12 August 2013

HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis

scientific article

Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection.

scientific article published in January 2004

Hepatitis C virus and alcohol: same mitotic targets but different signaling pathways

scientific article published on 22 December 2010

Heterologous T cell immunity in severe hepatitis C virus infection

scientific article

Human leukocyte antigen class I-independent pathways may contribute to hepatitis B virus-induced liver disease after liver transplantation

scientific article published in September 1993

Human leukocyte antigen class I-independent pathways may contribute to hepatitis B virus-induced liver disease after liver transplantation,

IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C.

scientific article published on 25 February 2011

IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection

scientific article

Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen

scientific article

Immune Gene Expression Profile in Hepatocellular Carcinoma and Surrounding Tissue Predicts Time to Tumor Recurrence

article

Immune landscape of hepatocellular carcinoma microenvironment: Implications for prognosis and therapeutic applications

scientific article published on 28 July 2019

Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.

scientific article

Immunological and molecular correlates of disease recurrence after liver resection for hepatocellular carcinoma.

scientific article

Immunopathogenesis of hepatitis B.

scientific article published on January 2003

Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection

scientific article published in January 2007

Impact of soluble CD26 on treatment outcome and hepatitis C virus-specific T cells in chronic hepatitis C virus genotype 1 infection

scientific article

Increased Immunostimulatory Activity Conferred to Antigen-presenting Cells by Exposure to Antigen Extract From Hepatocellular Carcinoma After Radiofrequency Thermal Ablation

scientific article published on 01 April 2008

Infection of circulating and liver infiltrating T cells by hepatitis C virus of different subtypes.

scientific article published on January 1995

Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection

scientific article

Interleukin 28B polymorphisms as predictors of sustained virological response in chronic hepatitis C: systematic review and meta-analysis.

scientific article published on 28 April 2015

Intrahepatic and circulating HLA class II-restricted, hepatitis C virus-specific T cells: functional characterization in patients with chronic hepatitis C.

scientific article published in May 2002

Intrahepatic mRNA levels of SOCS1 and SOCS3 are associated with cirrhosis but do not predict virological response to therapy in chronic hepatitis C.

scientific article published on 14 November 2012

Is there a role for immunotherapy in hepatocellular carcinoma?

scientific article

KIR/HLA immunogenetic background influences the evolution of hepatocellular carcinoma.

scientific article published on 21 October 2013

L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells.

scientific article

Lack of full CD8 functional restoration after antiviral treatment for acute and chronic hepatitis C virus infection.

scientific article published on 15 February 2012

Natural killer cell phenotype modulation and natural killer/T-cell interplay in nucleos(t)ide analogue-treated hepatitis e antigen-negative patients with chronic hepatitis B.

scientific article published on 11 September 2015

Natural killer cells phenotypic characterization as an outcome predictor of HCV-linked HCC after curative treatments

scientific article published on 4 March 2016

Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro.

scientific article published on February 2017

Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response

scientific article published in December 2002

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

scientific article published in July 2006

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

scientific article (publication date: November 2006)

Parenteral exposure to high HIV viremia leads to virus-specific T cell priming without evidence of infection.

scientific article published in November 2004

Percutaneous ultrasound-guided radiofrequency ablation of an allograft renal cell carcinoma: a case report.

scientific article

Radiofrequency Thermal Ablation for Hepatocellular Carcinoma Stimulates Autologous NK-Cell Response

article

Radiofrequency thermal ablation of hepatocellular carcinoma liver nodules can activate and enhance tumor-specific T-cell responses.

scientific article published in January 2006

Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms

scientific article

Restoration of HCV-specific T cell functions by PD-1/PD-L1 blockade in HCV infection: effect of viremia levels and antiviral treatment.

scientific article published on 28 January 2008

Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues

scientific article published on 14 July 2012

Rise and fall of HCV-related hepatocellular carcinoma in Italy: a long-term survey from the ITA.LI.CA centres

scientific article published on 12 June 2013

Role of immunoglobulin G fragment C receptor polymorphism-mediated antibody-dependant cellular cytotoxicity in colorectal cancer treated with cetuximab therapy.

scientific article

Role of viral and host factors in HCV persistence: which lesson for therapeutic and preventive strategies?

scientific article

Survival benefit of liver resection for patients with hepatocellular carcinoma across different Barcelona Clinic Liver Cancer stages: a multicentre study.

scientific article published on 30 October 2014

T cell regulation in HBV-related chronic liver disease.

scientific article published on 8 February 2017

Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B.

scientific article published on 6 February 2017

The changing scenario of hepatocellular carcinoma in Italy: an update

scientific article published on 20 November 2020

The characteristics of the cell-mediated immune response identify different profiles of occult hepatitis B virus infection.

scientific article published on 14 February 2008

The evolutionary scenario of hepatocellular carcinoma in Italy: an update.

scientific article published on 18 July 2016

Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B.

scientific article published in October 2003

Treatment optimization and prediction of HCV clearance in patients with acute HCV infection.

scientific article published on 12 April 2013

Utility of Tumor Burden Score to Stratify Prognosis of Patients with Hepatocellular Cancer: Results of 4759 Cases from ITA.LI.CA Study Group

scientific article published on 19 January 2018

Utility-based criteria for selecting patients with hepatocellular carcinoma for liver transplantation: A multicenter cohort study using the alpha-fetoprotein model as a survival predictor.

scientific article published on 16 July 2015

Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

scientific article (publication date: December 2002)

Years of life that could be saved from prevention of hepatocellular carcinoma

scientific article

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