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List of works by Niels H Gehring

3' UTR length and messenger ribonucleoprotein composition determine endocleavage efficiencies at termination codons.

scientific article published on 9 October 2014

3' end processing of the prothrombin mRNA in thrombophilia

scientific article

A Day in the Life of the Exon Junction Complex

scientific article published on 05 June 2020

A chemiluminescence-based reporter system to monitor nonsense-mediated mRNA decay

scientific article published in 2006

A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs

scientific article published on 14 January 2016

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain

scientific article published on 15 August 2019

Assembly, disassembly and recycling: the dynamics of exon junction complexes

scientific article published on January 2011

CWC22 connects pre-mRNA splicing and exon junction complex assembly

scientific article published on 6 September 2012

CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes

scientific article published on 13 April 2015

Deciphering the mRNP Code: RNA-Bound Determinants of Post-Transcriptional Gene Regulation

scientific article published on 3 March 2017

Detection and quantification of RNA decay intermediates using XRN1-resistant reporter transcripts

scientific article published on 24 April 2019

Disassembly of exon junction complexes by PYM

scientific article

Ecd promotes U5 snRNP maturation and Prp8 stability

scientific article published on 01 February 2021

Exon Junction Complexes: Supervising the Gene Expression Assembly Line

scientific article published on 22 September 2016

Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance

scientific article published on 01 June 2022

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

scientific article

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

scientific article

HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA.

scientific article

Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay

scientific article published on 22 November 2016

Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay

scientific article published on 22 April 2022

IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1)

scientific article

Increased efficiency of mRNA 3′ end formation: a new genetic mechanism contributing to hereditary thrombophilia

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

scientific article

Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay

scientific article published on 16 June 2006

Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences.

scientific article

Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon

scientific article

Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.

scientific article published on 18 August 2015

NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins

scientific article published on 17 December 2013

Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I.

scientific article

Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife

scientific article

Physiological and pathophysiological role of nonsense-mediated mRNA decay

scientific article published on 30 April 2016

Plasmid transfection influences the readout of nonsense-mediated mRNA decay reporter assays in human cells

scientific article published on 6 September 2017

SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity

scientific article published on 25 June 2021

Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2

scientific article

Studying the composition of mRNPs in vitro using splicing-competent cell extracts

scientific article published on 8 September 2013

The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway

scientific article published on 22 June 2007

The exon junction complex: structural insights into a faithful companion of mammalian mRNPs.

scientific article published on 19 January 2018

The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

scientific article

The human intronless melanocortin 4-receptor gene is NMD insensitive

scientific article (publication date: February 2002)

The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay

scientific article

The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons

scientific journal article

The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations

scientific article published in April 2004

The thrombopoietin receptor P106L mutation functionally separates receptor signaling activity from thrombopoietin homeostasis

scientific article

The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD).

scientific article

Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates

scientific article

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay

scientific article

Unexpected roles for UPF1 in HIV-1 RNA metabolism and translation

scientific article

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

scientific article

Y14 and hUpf3b form an NMD-activating complex

scientific article

mRNA metabolism and neuronal disease

scientific article published on 13 May 2015

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