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List of works by Tariq M. Haqqi

A Polyphenol-rich Pomegranate Fruit Extract Suppresses NF-κB and IL-6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes.

scientific article

Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro.

scientific article published on 13 June 2008

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8 ⬇️

scientific article

Chemical carcinogens increase IL-1 alpha and IL-6 gene transcripts in human keratinocytes

scientific article published on March 1993

Clinical correlations of osteoarthritis associated with a single-base mutation (arginine519 to cysteine) in type II procollagen gene. A newly defined pathogenesis

scientific article published on 01 February 1994

Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis.

scientific article published on 19 May 2008

Current nutraceuticals in the management of osteoarthritis: a review

scientific article

Delphinidin inhibits IL-1β-induced activation of NF-κB by modulating the phosphorylation of IRAK-1(Ser376) in human articular chondrocytes.

scientific article published on 7 February 2013

Direct ligation of PCR products for cloning and sequencing.

scientific article published on December 1992

Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes.

scientific article

Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes.

scientific article published on 6 September 2012

Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor

scientific article

Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes

scientific article

Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes.

scientific article published on 17 June 2011

Genetic inactivation of ZCCHC6 suppresses IL-6 expression and reduces the severity of experimental osteoarthritis in mice

scientific article published on 06 March 2019

Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene.

scientific article

Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes

scientific article published on 4 November 2003

Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes

scientific article published on 15 May 2009

Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes

scientific article published in October 2002

Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB.

scientific article published on 17 May 2006

Harpagoside suppresses IL-6 expression in primary human osteoarthritis chondrocytes

scientific article published on 15 April 2016

Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte

scientific article published on 20 August 2016

Histone deacetylase inhibitor vorinostat (SAHA, MK0683) perturb miR-9-MCPIP1 axis to block IL-1β-induced IL-6 expression in human OA chondrocytes

scientific article published on 12 July 2016

Human cartilage from late stage familial osteoarthritis transcribes type II collagen mRNA encoding a cysteine in position 519

scientific article published on 01 May 1993

Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2

scientific article published on 01 January 2002

Identification of T-cell receptor V beta deletion mutant mouse strain AU/ssJ (H-2q) which is resistant to collagen-induced arthritis

scientific article published on January 1989

Identification of plasma microRNA expression profile in radiographic axial spondyloarthritis-a pilot study.

scientific article published on 22 December 2015

Immunopathogenesis of osteoarthritis

scientific article

Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis.

scientific article published on 2 September 2016

Interleukin-1β induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes

scientific article published on 08 June 2016

Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells

scientific article published on 01 April 2000

Limited heterogeneity in T-cell receptor V beta chain gene expression in arthritic joints of BUB/BnJ (H-2q) mice--a T-cell receptor V beta a strain

scientific article published on 01 July 1995

MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes ⬇️

scientific article published on January 31, 2012

MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.

scientific article

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes

scientific article

MicroRNA-9 promotion of interleukin-6 expression by inhibiting monocyte chemoattractant protein-induced protein 1 expression in interleukin-1β-stimulated human chondrocytes

scientific article published in May 2015

Mitochondrial dysfunction triggers catabolic response in chondrocytes via ROS mediated activation of JNK/AP1 pathway

scientific article published on 23 October 2020

Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, α-Ketoglutarate (α-KG), and DNA hydroxymethylation levels by interleukin-1β in primary human chondrocytes

scientific article published on 27 January 2014

Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9.

scientific article published in October 2007

Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies

scientific article

Phenotypic modulation of newly synthesized proteoglycans in human cartilage and chondrocytes

scientific article published on 01 December 1995

Phenyl N-tert-butylnitrone down-regulates interleukin-1 beta-stimulated matrix metalloproteinase-13 gene expression in human chondrocytes: suppression of c-Jun NH2-terminal kinase, p38-mitogen-activated protein kinase and activating protein-1

scientific article published on 06 March 2003

Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes.

scientific article

Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea.

scientific article

Protective effects of C-type natriuretic peptide on linear growth and articular cartilage integrity in a mouse model of inflammatory arthritis ⬇️

scientific article

Restricted expression of T cell receptor V beta and lymphokine genes in arthritic joints of a TCR V beta a (H-2q) mouse strain-BUB/BnJ-with collagen-induced arthritis

scientific article published on 01 January 1995

Role of iNOS in osteoarthritis: Pathological and therapeutic aspects

scientific article published on 04 February 2020

Sister-chromatid exchanges and chromosomal aberrations in lymphocytes of male albino rats treated with an alkylating agent, apholate (NSC 26, 812; ENT 26, 316) ⬇️

scientific article published on 01 November 1984

Studies with chlorambucil. I. Effect on lactate dehydrogenase in the testes of albino rabbits treated with multiple doses of chlorambucil

scientific article published on 01 June 1983

Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway

scientific article published on 26 September 2016

Testicular damage and change in serum LDH isozyme pattern induced by multiple sub-lethal doses of apholate in albino rats

scientific article published on 01 July 1982

The Role of MicroRNAs and Their Targets in Osteoarthritis

scientific article

The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta

scientific article published on 7 April 2006

The effect of circulating serum factors from patients with systemic lupus erythematosus on protein kinase A (PKA) activity and PKA-dependent protein phosphorylation in T lymphocytes

scientific article published on 01 April 1993

Tumour necrosis factor alpha enhances the expression of hydroxyl lyase, cytoplasmic antiproteinase-2 and a dual specificity kinase TTK in human chondrocyte-like cells.

scientific article

miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes

scientific article

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