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List of works by Jakob Nilsson

A Consensus Binding Motif for the PP4 Protein Phosphatase

scientific article published on 01 October 2019

A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

scientific article published on 20 July 2016

A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

scientific article published on 30 September 2021

A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

scientific article published on 29 January 2014

A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment

scientific article published on 20 March 2020

A minimal number of MELT repeats supports all the functions of KNL1 in chromosome segregation

scientific article published on 20 December 2013

A role for the basic patch and the C terminus of RanGTP in regulating the dynamic interactions with importin beta, CRM1 and RanBP1.

scientific article

A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export

scientific article

Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

scientific article published on 12 June 2017

Bub1/BubR1: swiss army knives at kinetochores

scientific article published on 11 August 2015

CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain

scientific article

Can sequestering of mitotic spindle proteins cause aneuploidy? (Comment on DOI 10.1002/bies.201400175)

scientific article published on 16 January 2015

Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?

scientific article

Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments

scientific article published on 20 March 2007

Comprehensive identification of SUMO2/3 targets and their dynamics during mitosis

scientific article

Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling

scientific article

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development ⬇️

scientific article published on 06 June 2016

Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae

scientific article

DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

scientific article

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

scientific article published on 23 January 2013

Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint

scientific article

Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis.

scientific article published on 30 October 2017

Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

scientific article published on 19 February 2019

Elongation factors on the ribosome

scientific article

Escape from the checkpoint: Nek2A binds a unique conformation of the APC/C-MCC complex

scientific article published on 19 May 2020

Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM.

scientific article

Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry

scientific article

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

scientific article published on 19 November 2021

Localization of PP2A-B56 to centromeres in Drosophila

scientific article published on 19 July 2017

Looping in on Ndc80 – How does a protein loop at the kinetochore control chromosome segregation? ⬇️

scientific article published on December 1, 2012

Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

scientific article

Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits

scientific article published on 13 May 2020

Mps1-Ndc80: one interaction to rule them all.

scientific article published in July 2015

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

scientific article published on 01 September 2018

Protein phosphatases in the regulation of mitosis

scientific article published on 16 November 2018

Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome

scientific article

Response to Raaijmakers & Medema

scientific article published on 22 October 2019

SAC during early cell divisions: Sacrificing fidelity over timely division, regulated differently across organisms: Chromosome alignment and segregation are left unsupervised from the onset of development until checkpoint activity is acquired, varyi

scientific article published on 30 November 2020

Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions

scientific article published on 05 June 2020

Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

scientific article published on 25 January 2014

Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site

scientific article

Structure of the RACK1 dimer from Saccharomyces cerevisiae

scientific article

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

scientific article

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C.

scientific article published on 2 September 2016

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

scientific article

The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form

scientific article published in April 2002

The Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal region

scientific article (publication date: 2013)

The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30.

scientific article published on 27 December 2017

The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions

scientific article published in 2024

The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores

scientific article

The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity

scientific article

The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

scientific article published on January 2012

The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores

scientific article published on 23 July 2018

The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

scientific article published on 8 December 2014

The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP.

scientific article

TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

scientific article published on August 2015

Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis.

scientific article published on 19 November 2012

Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

scientific article published on 26 July 2016

Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy

scientific article

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