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List of works by Paul Lingor

AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury

scientific article published on 13 April 2015

AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo

scientific article published on 26 February 2021

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo

scientific article published on 2 October 2014

Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner

scientific article published on July 2010

Acute onset of adult Alexander disease

scientific article published on 23 May 2013

Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.

scientific article

Alpha-synuclein and iron: two keys unlocking Parkinson's disease.

scientific article published on 6 February 2017

Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease.

scientific article published on 10 September 2014

Angiographic CT with intravenous administration of contrast medium is a noninvasive option for follow-up after intracranial stenting.

scientific article

Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.

scientific article published on 5 January 2016

Axonal degeneration as a therapeutic target in the CNS.

scientific article published on 06 March 2012

BAG1 is neuroprotective in in vivo and in vitro models of Parkinson's disease

scientific article

BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity.

scientific article published on 29 August 2008

Baseline Cerebrospinal Fluid α-Synuclein in Parkinson's Disease Is Associated with Disease Progression and Cognitive Decline

scientific article published on 18 May 2022

Calcium channel inhibition-mediated axonal stabilization improves axonal regeneration after optic nerve crush.

scientific article published in August 2016

Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration

scientific article

Cerebellar-type multiple system atrophy presenting with leucoencephalopathy

scientific article published on 28 November 2010

Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS)

scientific article published on 17 March 2012

Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells

scientific article published on 25 September 2009

Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis

scientific article published on 12 January 2007

Differential transgene expression in brain cells in vivo and in vitro from AAV-2 vectors with small transcriptional control units.

scientific article

Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo.

scientific article published on 19 January 2005

Early and sustained activation of autophagy in degenerating axons after spinal cord injury

scientific journal article

Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson's disease

scientific article published in February 2018

Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells

scientific article

Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease

scientific article published on 22 April 2016

Functional applications of novel Semliki Forest virus vectors are limited by vector toxicity in cultures of primary neurons in vitro and in the substantia nigra in vivo

scientific article published on 20 October 2004

GDF-15/MIC-1 a novel member of the TGF-beta superfamily.

scientific article

GDNF and NT-4 protect midbrain dopaminergic neurons from toxic damage by iron and nitric oxide.

scientific article

Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease.

scientific article published on 29 March 2006

Growth/differentiation factor-15/macrophage inhibitory cytokine-1 is a novel trophic factor for midbrain dopaminergic neurons in vivo

scientific article published on 01 December 2000

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo.

scientific article published on 26 April 2011

Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen

scientific article

Imaging of rat optic nerve axons in vivo

scientific article

Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism

scientific article published in June 2006

Increased alpha-synuclein tear fluid levels in patients with Parkinson's disease

scientific article published on 22 May 2020

Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo

scientific article

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

scientific article

Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing

scientific article published on 27 April 2020

Insights on the interaction of alpha-synuclein and metals in the pathophysiology of Parkinson's disease

scientific article

JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.

scientific article

Mechanisms of acute axonal degeneration in the optic nerve in vivo

scientific article

Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.

scientific article published on 6 November 2007

Metal dyshomeostasis in the substantia nigra of patients with Parkinson's disease or multiple sclerosis

scientific article published in 2024

Midbrain dopaminergic neurons are protected from radical induced damage by GDF-5 application. Short communication

scientific article published in January 1999

Multi-omic landscaping of human midbrains identifies disease-relevant molecular targets and pathways in advanced-stage Parkinson's disease

scientific article published on 01 January 2022

Paraneoplastic polymyositis in recurring adrenal gland carcinoma

scientific article published in July 2003

Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression.

scientific article published in September 2011

Proteomic analysis of tear fluid reveals disease-specific patterns in patients with Parkinson's disease - A pilot study

scientific article published on 06 March 2019

ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells

scientific article published on 5 December 2007

ROCK inhibition in models of neurodegeneration and its potential for clinical translation

scientific article published on 2 April 2018

ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.

scientific article

ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.

scientific article

Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset

scientific article published on 31 January 2017

Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease

scientific article published in August 2014

Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.

scientific article published on 6 December 2013

Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro.

scientific article published on 8 May 2004

Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.

scientific article published in July 2009

Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons

scientific article published on 12 May 2006

TDP-43 as structure-based biomarker in amyotrophic lateral sclerosis

scientific article published on 02 December 2020

TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP.

scientific article published on 6 March 2010

Targeting neurological disease with RNAi.

scientific article published on 29 August 2007

The long processes of short interfering RNAs--RNA interference and its implications in neuronal cells.

scientific article published on January 2004

The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice

scientific article

The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.

scientific article published on 14 September 2011

Transfection of "naked" siRNA results in endosomal uptake and metabolic impairment in cultured neurons

scientific article published in March 2004

Unilateral phrenic nerve lesion in Lyme neuroborreliosis.

scientific article

Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro.

scientific article

Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells

scientific article

X‐ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons ⬇️

scientific article published on December 5, 2012

[Arndt-Gottron syndrome with encephalopathy: complete recovery after immunosuppressive therapy]

scientific article published on 01 October 2011

α-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons.

scientific article

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