List of works - Juha T Huiskonen

A Molecular-Level Account of the Antigenic Hantaviral Surface

scientific article

A Molecular-Level Account of the Antigenic Hantaviral Surface

A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

scientific article published on 01 December 2018

Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike

scientific article published on 5 February 2016

Assembly of complex viruses exemplified by a halophilic euryarchaeal virus

scientific article published on 29 March 2019

Assessment of Immunogenicity and Efficacy of a Zika Vaccine Using Modified Vaccinia Ankara Virus as Carriers

scientific article published on 02 November 2019

Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus

scientific article published on 03 April 2019

Averaging of viral envelope glycoprotein spikes from electron cryotomography reconstructions using Jsubtomo

scientific article

Beyond structures of highly symmetric purified viral capsids by cryo-EM

scientific article published on 07 August 2018

Building bridges between cellular and molecular structural biology

scientific article

Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus

scientific article published on 15 October 2018

Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles.

scientific article published on 19 April 2005

Cryo electron tomography of herpes simplex virus during axonal transport and secondary envelopment in primary neurons.

scientific article

Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution

scientific article published in 2022

Crystal Structure of Venezuelan Hemorrhagic Fever Virus Fusion Glycoprotein Reveals a Class 1 Postfusion Architecture with Extensive Glycosylation

scientific article

Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility

scientific article published on January 2015

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping

scientific article

Drastic changes in conformational dynamics of the antiterminator M2-1 regulate transcription efficiency in Pneumovirinae

scientific article

Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly

article

Editorial overview: Virus structure and assembly: Virions - from structure and physics to design principles

scientific article published in June 2016

Efficient production of Rift Valley fever virus-like particles: The antiviral protein MxA can inhibit primary transcription of bunyaviruses

scientific article

Eisosome proteins assemble into a membrane scaffold

scientific article

Eisosome-driven plasma membrane organization is mediated by BAR domains

scientific article

Electron cryo-microscopy and single-particle averaging of Rift Valley fever virus: evidence for GN-GC glycoprotein heterodimers

scientific article published on 4 February 2009

Electron cryomicroscopy comparison of the architectures of the enveloped bacteriophages phi6 and phi8

scientific article published on 01 February 2007

Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses

scientific article

Electron cryotomography of measles virus reveals how matrix protein coats the ribonucleocapsid within intact virions

scientific article published on 24 October 2011

Image processing for cryogenic transmission electron microscopy of symmetry-mismatched complexes.

scientific article published on 8 February 2018

Insights into bunyavirus architecture from electron cryotomography of Uukuniemi virus

scientific article

Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus

scientific article published on 21 October 2013

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes

scientific article

Membrane proteins modulate the bilayer curvature in the bacterial virus Bam35.

scientific article published on December 2005

Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid

scientific article

Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2

scientific journal article

Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein

scientific article published on 22 December 2020

Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus

scientific article published on 29 May 2019

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

scientific article published on 04 July 2018

Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

scientific article

Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein

scientific article

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike

scientific article published in 2013

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

scientific article

Shielding and activation of a viral membrane fusion protein

scientific article published on 24 January 2018

Snapshot of virus evolution in hypersaline environments from the characterization of a membrane-containing Salisaeta icosahedral phage 1.

scientific article

Structural plasticity of the Semliki Forest virus glycome upon interspecies transmission.

scientific article

Structural transitions of the conserved and metastable hantaviral glycoprotein envelope

scientific article

Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus

scientific article

Structure and interactions of the endogenous human Commander complex

scientific article published in 2024

Structure of a hexameric RNA packaging motor in a viral polymerase complex.

scientific article published on 7 October 2006

Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion

scientific article

Structure of the Lassa virus glycan shield provides a model for immunological resistance

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure of the bacteriophage phi6 nucleocapsid suggests a mechanism for sequential RNA packaging

scientific article published in June 2006

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).

scientific article published on 19 December 2016

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design

scientific article

Structures of enveloped virions determined by cryogenic electron microscopy and tomography

scientific article published on 20 August 2019

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

scientific article published on 22 September 2017

Tale of two spikes in bacteriophage PRD1

scholarly article

The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes

scientific article

The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction

scientific article

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

scientific article published on 02 September 2019

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins

scientific article published on 19 February 2019

The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture.

scientific article

Towards in cellulo virus crystallography

scientific article published on 28 February 2018

Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways

scientific article published on 20 April 2019

Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging.

scientific article published on 10 November 2017

Uukuniemi Phlebovirus assembly and secretion leave a functional imprint on the virion glycome

scientific article

Virus found in a boreal lake links ssDNA and dsDNA viruses

scientific article published on 17 July 2017

List of works by Juha T Huiskonen

A Molecular-Level Account of the Antigenic Hantaviral Surface

A Molecular-Level Account of the Antigenic Hantaviral Surface

A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike

Assembly of complex viruses exemplified by a halophilic euryarchaeal virus

Assessment of Immunogenicity and Efficacy of a Zika Vaccine Using Modified Vaccinia Ankara Virus as Carriers

Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus

Averaging of viral envelope glycoprotein spikes from electron cryotomography reconstructions using Jsubtomo

Beyond structures of highly symmetric purified viral capsids by cryo-EM

Building bridges between cellular and molecular structural biology

Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus

Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles.

Cryo electron tomography of herpes simplex virus during axonal transport and secondary envelopment in primary neurons.

Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution

Crystal Structure of Venezuelan Hemorrhagic Fever Virus Fusion Glycoprotein Reveals a Class 1 Postfusion Architecture with Extensive Glycosylation

Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping

Drastic changes in conformational dynamics of the antiterminator M2-1 regulate transcription efficiency in Pneumovirinae

Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly

Editorial overview: Virus structure and assembly: Virions - from structure and physics to design principles

Efficient production of Rift Valley fever virus-like particles: The antiviral protein MxA can inhibit primary transcription of bunyaviruses

Eisosome proteins assemble into a membrane scaffold

Eisosome-driven plasma membrane organization is mediated by BAR domains

Electron cryo-microscopy and single-particle averaging of Rift Valley fever virus: evidence for GN-GC glycoprotein heterodimers

Electron cryomicroscopy comparison of the architectures of the enveloped bacteriophages phi6 and phi8

Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses

Electron cryotomography of measles virus reveals how matrix protein coats the ribonucleocapsid within intact virions

Image processing for cryogenic transmission electron microscopy of symmetry-mismatched complexes.

Insights into bunyavirus architecture from electron cryotomography of Uukuniemi virus

Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes

Membrane proteins modulate the bilayer curvature in the bacterial virus Bam35.

Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid

Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2

Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein

Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

Shielding and activation of a viral membrane fusion protein

Snapshot of virus evolution in hypersaline environments from the characterization of a membrane-containing Salisaeta icosahedral phage 1.

Structural plasticity of the Semliki Forest virus glycome upon interspecies transmission.

Structural transitions of the conserved and metastable hantaviral glycoprotein envelope

Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus

Structure and interactions of the endogenous human Commander complex

Structure of a hexameric RNA packaging motor in a viral polymerase complex.

Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion

Structure of the Lassa virus glycan shield provides a model for immunological resistance

Structure of the bacteriophage phi6 nucleocapsid suggests a mechanism for sequential RNA packaging

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design

Structures of enveloped virions determined by cryogenic electron microscopy and tomography

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

Tale of two spikes in bacteriophage PRD1

The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes

The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins

The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture.

Towards in cellulo virus crystallography

Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways

Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging.

Uukuniemi Phlebovirus assembly and secretion leave a functional imprint on the virion glycome

Virus found in a boreal lake links ssDNA and dsDNA viruses