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List of works by Lih-Chu Chiou

1-Benzyl-N-[3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl]pyrrolidine-2-carboxamide (Compound 24) antagonizes NOP receptor-mediated potassium channel activation in rat periaqueductal gray slices

scientific article published in February 2009

A comparison of the antagonisms by neostigmine and diaminopyridine against the neuromuscular block caused by cobrotoxin and (+)-tubocurarine

scientific article published in 1986

A selective inhibitor of cAMP-specific phosphodiesterase, Ro 20-1724, has no effect on the quantal release of acetylcholine from the mouse phrenic nerve

scientific article published on 01 February 1988

Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition

scientific article published on October 2011

Antagonism by beta-eudesmol of neostigmine-induced neuromuscular failure in mouse diaphragms

scientific article published on 01 June 1992

Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain

scientific article published on 9 October 2003

Calcitonin gene-related peptide and size of the atrial septal defect in new-onset migraine after transcatheter closure: results of a preliminary study.

scientific article published on 5 April 2012

Cerebellar α6 subunit-containing GABAA receptors: A novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.

scientific article published on 8 March 2018

Characterization of synaptic transmission in the ventrolateral periaqueductal gray of rat brain slices

scientific article published on 01 January 2000

Chinese herb constituent beta-eudesmol alleviated the electroshock seizures in mice and electrographic seizures in rat hippocampal slices

scientific article published in August 1997

CompB (J-113397), selectively and competitively antagonizes nociceptin activation of inwardly rectifying K(+) channels in rat periaqueductal gray slices

scientific article

Conditioned place preference training prevents hippocampal depotentiation in an orexin-dependent manner.

scientific article published on 6 September 2017

Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability.

scientific article published on 26 February 2018

Different trigemino-vascular responsiveness between adolescent and adult rats in a migraine model

scientific article published on 26 July 2012

Differential antagonism by naloxone benzoylhydrazone of the activation of inward rectifying K+ channels by nociceptin and a mu-opioid in rat periaqueductal grey slices

scientific article published in June 2001

Differential pharmacological actions of methadone and buprenorphine in human embryonic kidney 293 cells coexpressing human μ-opioid and opioid receptor-like 1 receptors.

scientific article

Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus

scientific article published on 01 August 2000

Does endogenous adenosine modulate the release of acetylcholine from motor nerve during single and repetitive stimulations in the mouse diaphragm?

scientific article published on 01 August 1987

Does gabapentin act as an agonist at native GABA(B) receptors?

scientific article published in May 2004

Effects of intrathecal injection of T-type calcium channel blockers in the rat formalin test

scientific article published on 01 February 2007

Electrophysiological study on the effects of leptin in rat dorsal motor nucleus of the vagus.

scientific article published on 15 February 2007

Elevated plasma orexin A levels in a subgroup of patients with schizophrenia associated with fewer negative and disorganized symptoms

scientific article published on 20 December 2014

Enhancement by benzodiazepines of the inhibitory effect of adenosine on skeletal neuromuscular transmission

scientific article

Functional heterogeneity of nociceptin/orphanin FQ receptors revealed by (+)-5a Compound and Ro 64-6198 in rat periaqueductal grey slices

scientific article published on 29 October 2010

Hispidulin alleviated methamphetamine-induced hyperlocomotion by acting at α6 subunit-containing GABAA receptors in the cerebellum

scientific article published on 6 July 2016

Hispidulin attenuates the social withdrawal in isolated disrupted-in-schizophrenia-1 mutant and chronic phencyclidine-treated mice

scientific article published on 04 March 2020

Hispidulin, a constituent of Clerodendrum inerme that remitted motor tics, alleviated methamphetamine-induced hyperlocomotion without motor impairment in mice

scientific article

Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic pain

scientific article published in May 2013

Impairment of adenylyl cyclase-mediated glutamatergic synaptic plasticity in the periaqueductal grey in a rat model of neuropathic pain

scientific article published on 14 May 2015

Intractable chronic motor tics dramatically respond to Clerodendrum inerme (L) Gaertn.

scientific article published in July 2009

Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain

scientific article published in June 2003

Mechanism underlying increased neuronal activity in the rat ventrolateral periaqueductal grey by a mu-opioid

scientific article published in July 1999

Mechanisms of the antinociceptive action of gabapentin.

scientific article

Neuromuscular block by verapamil and diltiazem and inhibition of acetylcholine release

scientific article published on 01 June 1988

Neuropeptide S-initiated sequential cascade mediated by OX1, NK1, mGlu5 and CB1 receptors: a pivotal role in stress-induced analgesia

scientific article published on 09 January 2020

Obidoxime Antagonizes the Neuromuscular Failure Induced by Neostigmine and Diisopropyl Fluorophosphate via Different Mechanisms

scientific article published on 01 December 1994

Orexin A induces bidirectional modulation of synaptic plasticity: Inhibiting long-term potentiation and preventing depotentiation

scientific article published on 7 March 2016

Orexin-mediated restoration of hippocampal synaptic potentiation in mice with established cocaine-conditioned place preference

scientific article published on 01 October 2018

Orexin/hypocretin role in reward: implications for opioid and other addictions

scientific article

Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons.

scientific article published on 22 July 2016

Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors

scientific article published on 21 May 2010

Orexins/hypocretins: pain regulation and cellular actions

scientific article published on January 2010

Pharmacological characterization of nociceptin/orphanin FQ receptors, a novel opioid receptor family, in the midbrain periaqueductal gray.

scientific article

Pharmacological relevance of peripheral type benzodiazepine receptors on motor nerve and skeletal muscle.

scientific article published in May 1994

Plasma calcitonin gene-related peptide in diagnosing and predicting paediatric migraine.

scientific article published on 19 February 2009

Prenatal morphine exposure decreases analgesia but not K+ channel activation

scientific article published in February 2003

Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices

article by Chia-Ju Kuo et al published January 2008 in European Journal of Pharmacology

Quantitative study of [Tyr10]nociceptin/orphanin FQ (1-11) at NOP receptors in rat periaqueductal gray and expressed NOP receptors in HEK293 cells.

scientific article

Quantitative study of the antagonistic effect of (-)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111) on nociceptin/orphanin FQ-mediated potassium channel activation in rat periaqu

scientific article published on 11 February 2011

Ro 64-6198 [(1S,3aS)-8-(2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one] acts differently from nociceptin/orphanin FQ in rat periaqueductal gray slices

scientific article published on 13 July 2004

Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice.

scientific article published on 3 September 2009

Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray

scientific article published on 18 February 2016

Stress induces reinstatement of extinguished cocaine conditioned place preference by a sequential signaling via neuropeptide S, orexin, and endocannabinoid

scientific article published on 19 October 2020

Targeting the cannabinoid system for pain relief?

scientific article published on 25 December 2013

The antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or N-methyl-d-aspartic acid receptors?

scientific article published in January 2006

The α6 subunit-containing GABA receptor: A novel drug target for inhibition of trigeminal activation

scholarly article by Pi-Chuan Fan et al published 15 September 2018 in Neuropharmacology

Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative.

scientific article published on 4 November 2017

Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1

scientific article

[Nphe(1)]N/OFQ-(1-13)-NH(2) is a competitive and selective antagonist at nociceptin/orphanin FQ receptors mediating K(+) channel activation in rat periaqueductal gray slices

scientific article published in February 2002

[Nphe1,Arg14,Lys15]N/OFQ-NH2 is a competitive antagonist of NOP receptors in the periaqueductal gray

article by Lih-Chu Chiou et al published May 2005 in European Journal of Pharmacology

[Phe1psi(CH2-NH)Gly2]nociceptin-(1 - 13)-NH2 activation of an inward rectifier as a partial agonist of ORL1 receptors in rat periaqueductal gray.

scientific article

beta-Eudesmol as an antidote for intoxication from organophosphorus anticholinesterase agents

scientific article published on 01 January 1995

α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia

scientific article published on 27 October 2020

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