List of works by Jose Luis Sanchez-Quesada

2D-NMR reveals different populations of exposed lysine residues in the apoB-100 protein of electronegative and electropositive fractions of LDL particles

scientific article published on 28 January 2010

Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice

scientific article published in PLoS ONE

Aggregated electronegative low density lipoprotein in human plasma shows a high tendency toward phospholipolysis and particle fusion

scientific article published on 29 July 2010

Apo(B)-dependent dyslipidemic phenotypes in type 1 diabetic patients.

scientific article published in December 2001

Ascorbic acid inhibits the increase in low-density lipoprotein (LDL) susceptibility to oxidation and the proportion of electronegative LDL induced by intense aerobic exercise

scientific article published on 01 January 1998

Atherogenic and inflammatory profile of human arterial endothelial cells (HUAEC) in response to LDL subfractions.

scientific article published on 29 July 2006

Atherogenic properties of lipoproteins in HIV patients starting atazanavir/ritonavir or darunavir/ritonavir: a substudy of the ATADAR randomized study

scientific article published on 23 December 2014

Bariatric surgery in morbidly obese patients improves the atherogenic qualitative properties of the plasma lipoproteins

scientific article published on 14 March 2014

CD14 and TLR4 mediate cytokine release promoted by electronegative LDL in monocytes.

scientific article published on 18 May 2013

Ceramide-enriched LDL induces cytokine release through TLR4 and CD14 in monocytes. Similarities with electronegative LDL.

scientific article published on 12 March 2014

Changes in low-density lipoprotein electronegativity and oxidizability after aerobic exercise are related to the increase in associated non-esterified fatty acids

scientific article published in January 2002

Clusterin/apolipoprotein J binds to aggregated LDL in human plasma and plays a protective role against LDL aggregation.

scientific article published on 30 December 2014

Consumption of polyunsaturated fat improves the saturated fatty acid-mediated impairment of HDL antioxidant potential

scientific article published on 29 June 2015

Density distribution of electronegative LDL in normolipemic and hyperlipemic subjects.

scientific article published in May 2002

Early intervention in the 3xTg-AD mice with an amyloid β-antibody fragment ameliorates first hallmarks of Alzheimer disease.

scientific article published on 20 June 2013

Effect of glycemic optimization on electronegative low-density lipoprotein in diabetes: relation to nonenzymatic glycosylation and oxidative modification

scientific article published in July 2001

Effect of improving glycemic control in patients with type 2 diabetes mellitus on low-density lipoprotein size, electronegative low-density lipoprotein and lipoprotein-associated phospholipase A2 distribution

scientific article published on 3 April 2012

Effect of physical exercise on lipoprotein(a) and low-density lipoprotein modifications in Type 1 and Type 2 diabetic patients

scientific article published on 01 May 2000

Effect of simvastatin in familial hypercholesterolemia on the affinity of electronegative low-density lipoprotein subfractions to the low-density lipoprotein receptor

scientific article published in February 2004

Effect of simvastatin treatment on the electronegative low-density lipoprotein present in patients with heterozygous familial hypercholesterolemia

scientific article

Effect of statin and fibrate treatment on inflammation in type 2 diabetes. A randomized, cross-over study

scientific article published on 26 March 2011

Effects of multilayered bags vs ethylvinyl-acetate bags on oxidation of parenteral nutrition

scientific article published in March 2004

Electronegative LDL Promotes Inflammation and Triglyceride Accumulation in Macrophages

scientific article published on 01 March 2020

Electronegative LDL from normolipemic subjects induces IL-8 and monocyte chemotactic protein secretion by human endothelial cells

scientific article published on 01 October 2000

Electronegative LDL induces Fas and modifies gene expression in mononuclear cells.

scientific article published in January 2010

Electronegative LDL induces priming and inflammasome activation leading to IL-1β release in human monocytes and macrophages.

scientific article published on 28 August 2015

Electronegative LDL of FH subjects: chemical characterization and induction of chemokine release from human endothelial cells.

scientific article published in February 2003

Electronegative LDL: a circulating modified LDL with a role in inflammation

scientific article

Electronegative low density lipoprotein subform is increased in patients with short-duration IDDM and is closely related to glycaemic control

scientific article published on 01 December 1996

Electronegative low-density lipoprotein subfraction from type 2 diabetic subjects is proatherogenic and unrelated to glycemic control

scientific article published on 01 January 2007

Electronegative low-density lipoprotein. A link between apolipoprotein B misfolding, lipoprotein aggregation and proteoglycan binding.

scientific article published on October 2012

Familial Combined Hyperlipidemia (FCH) Patients with High Triglyceride Levels Present with Worse Lipoprotein Function Than FCH Patients with Isolated Hypercholesterolemia

scientific article published on 06 January 2020

HDL and electronegative LDL exchange anti- and pro-inflammatory properties

scientific article published on 20 July 2010

High binding affinity of electronegative LDL to human aortic proteoglycans depends on its aggregation level.

scientific article

Human ApoA-I Overexpression Enhances Macrophage-Specific Reverse Cholesterol Transport but Fails to Prevent Inherited Diabesity in Mice ⬇️

scientific article published on 02 February 2019

Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential.

scientific article published on 23 September 2004

Hypovitaminosis D in type 2 diabetes: relation with features of the metabolic syndrome and glycemic control

scientific article published on 23 December 2014

Hypoxia worsens the impact of intracellular triglyceride accumulation promoted by electronegative low-density lipoprotein in cardiomyocytes by impairing perilipin 5 upregulation.

scientific article published on 19 June 2015

Immunochemical analysis of the electronegative LDL subfraction shows that abnormal N-terminal apolipoprotein B conformation is involved in increased binding to proteoglycans

scientific article published on 15 November 2010

Impaired binding affinity of electronegative low-density lipoprotein (LDL) to the LDL receptor is related to nonesterified fatty acids and lysophosphatidylcholine content

scientific article published in December 2004

Inaccuracy of calculated LDL-cholesterol in type 2 diabetes: consequences for patient risk classification and therapeutic decisions.

scientific article published in November 2000

Increase of LDL susceptibility to oxidation occurring after intense, long duration aerobic exercise.

scientific article published in December 1995

Increased concentration of clusterin/apolipoprotein J (apoJ) in hyperlipemic serum is paradoxically associated with decreased apoJ content in lipoproteins

scientific article published on 06 June 2015

Increased lysophosphatidylcholine and non-esterified fatty acid content in LDL induces chemokine release in endothelial cells. Relationship with electronegative LDL.

scientific article published in December 2004

Inflammatory biomarkers in type 2 diabetic patients: effect of glycemic control and impact of LDL subfraction phenotype

scientific article published on 04 February 2014

Inflammatory intracellular pathways activated by electronegative LDL in monocytes.

scientific article

LDL from aerobically-trained subjects shows higher resistance to oxidative modification than LDL from sedentary subjects

scientific article published on 01 July 1997

LDL subclasses and lipoprotein-phospholipase A2 activity in suppressed HIV-infected patients switching to raltegravir: Spiral substudy

scientific article published on 6 September 2012

Mechanisms of HDL deficiency in mice overexpressing human apoA-II.

scientific article published in October 2002

Methionine-induced hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins without reducing in vivo macrophage-specific reverse cholesterol transport.

scientific article published on 10 June 2013

Modified lipoproteins as biomarkers of cardiovascular risk in diabetes mellitus.

scientific article published on 29 March 2013

Molecular requirements in the recognition of low-density lipoproteins (LDL) by specific platelet membrane receptors

scientific article published on 01 July 2000

Novel phospholipolytic activities associated with electronegative low-density lipoprotein are involved in increased self-aggregation.

scientific article published on 8 July 2008

Phytosterols inhibit the tumor growth and lipoprotein oxidizability induced by a high-fat diet in mice with inherited breast cancer.

scientific article published on 30 May 2012

Platelet-Activating Factor Acetylhydrolase Is Mainly Associated With Electronegative Low-Density Lipoprotein Subfraction

scientific article published on 23 June 2003

Postprandial lipidemia is normal in non-obese type 2 diabetic patients with relatively preserved insulin secretion.

scientific article published in August 2003

Prevalence and Phenotypic Distribution of Dyslipidemia in Type 1 Diabetes Mellitus

scientific article published on 01 October 2000

Prevalence of metabolic syndrome among human immunodeficiency virus-infected subjects is widely influenced by the diagnostic criteria.

scientific article published on 4 May 2011

Pro-inflammatory action of LDL(-) on mononuclear cells is counteracted by increased IL10 production

scientific article

Proteomic analysis of electronegative low-density lipoprotein

scientific article published on 10 August 2010

Response of oxidative stress biomarkers to a 16-week aerobic physical activity program, and to acute physical activity, in healthy young men and women.

scientific article

Subcutaneous Administration of Apolipoprotein J-Derived Mimetic Peptide d-[113-122]apoJ Improves LDL and HDL Function and Prevents Atherosclerosis in LDLR-KO Mice

scientific article published on 29 May 2020

Susceptibility of plasma low- and high-density lipoproteins to oxidation in patients with severe hyperhomocysteinemia

scientific article published on 01 December 1996

Switching to basal-bolus insulin therapy is effective and safe in long-term type 2 diabetes patients inadequately controlled with other insulin regimens

scientific article published on 22 March 2013

The Induction of Cytokine Release in Monocytes by Electronegative Low-Density Lipoprotein (LDL) Is Related to Its Higher Ceramide Content than Native LDL.

scientific article

The association of hypovitaminosis d with the metabolic syndrome is independent of the degree of obesity.

scientific article

The inflammatory properties of electronegative low-density lipoprotein from type 1 diabetic patients are related to increased platelet-activating factor acetylhydrolase activity.

scientific article published on 18 August 2005

Thermal stability of human plasma electronegative low-density lipoprotein: A paradoxical behavior of low-density lipoprotein aggregation.

scientific article published on 24 May 2016

Triglyceride increase in the core of high-density lipoproteins augments apolipoprotein dissociation from the surface: Potential implications for treatment of apolipoprotein deposition diseases

scientific article published on 18 October 2016

Triglyceride-to-HDL cholesterol ratio in the dyslipidemic classification of type 2 diabetes

scientific article published in July 2005

Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment.

scientific article published on 22 January 2014

Which cholesterol are we measuring with the Roche direct, homogeneous LDL-C Plus assay?

scientific article

Wide proinflammatory effect of electronegative low-density lipoprotein on human endothelial cells assayed by a protein array

scientific article published on 01 April 2006

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