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List of works by Seth B. Coffelt

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

scientific article published on 2 March 2011

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

scientific article published on 8 June 2010

Author Correction: CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.

scientific article published on 13 April 2018

CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity

scientific article published on 4 December 2017

Emerging immunotherapies for metastasis

scientific article published on 02 December 2020

Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications.

scientific article

Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells

scientific article published on 01 April 2007

Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients

scientific article published in March 2014

Generation of a novel mouse model for the inducible depletion of macrophages in vivo

scientific article published on 20 September 2012

Gut γδ T cells as guardians, disruptors, and instigators of cancer

scientific article published on 24 August 2020

Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

scientific article

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

scientific article published on 30 March 2015

Immune-mediated mechanisms influencing the efficacy of anticancer therapies.

scientific article published on April 2015

Impact of Formate Supplementation on Body Weight and Plasma Amino Acids

scientific article published on 22 July 2020

Incidence of lymph node metastases in clinical early-stage mucinous and seromucinous ovarian carcinoma: a retrospective cohort study.

scientific article published on 16 November 2016

Inflammation lights the way to metastasis

scientific article published in Nature

Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal transduction pathways, stimulate oncogenic gene expression, and enhance the invasiveness of ovarian cancer cells.

scientific article

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis

scientific article published on 31 July 2019

Macrophages and Neutrophils: Regulation of the Inflammatory Microenvironment in Autoimmunity and Cancer.

scientific article

Macrophages promote the progression of premalignant mammary lesions to invasive cancer

scientific article published on 31 January 2017

Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.

scientific article published on 19 June 2017

Monocyte Subpopulations from Pre-Eclamptic Patients Are Abnormally Skewed and Exhibit Exaggerated Responses to Toll-Like Receptor Ligands ⬇️

scientific article published on July 27, 2012

Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2⁺ breast cancer

scientific article published on 01 August 2015

Neutrophil Maturity in Cancer

scientific article published on 14 August 2019

Neutrophils in cancer: neutral no more.

scientific article

OS006. Functional expression of endogenous ligands of Toll like receptor4 on monocytes and placentae from women during normal pregnancy andpre-eclampsia

scientific article published on 13 June 2012

Period-2: a tumor suppressor gene in breast cancer.

scientific article published on 11 March 2008

PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development

scientific article published on 8 December 2017

Repression of the Type I Interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in Pancreatic Ductal Adenocarcinoma

scientific article published on 21 March 2020

Revving Up Dendritic Cells while Braking PD-L1 to Jump-Start the Cancer-Immunity Cycle Motor

scientific article

Systemic inflammation: Cancer's long-distance reach to maximize metastasis.

scientific article published on 17 August 2015

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

scientific article

The ERBB network facilitates KRAS-driven lung tumorigenesis

scientific article published on 01 June 2018

The autophagic paradox in cancer therapy ⬇️

scientific article published on July 18, 2011

The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.

scientific article

The role of myeloid cells in the promotion of tumour angiogenesis

scientific article (publication date: August 2008)

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response

scientific article published on 18 March 2019

Toll-like receptor 3 and suppressor of cytokine signaling proteins regulate CXCR4 and CXCR7 expression in bone marrow-derived human multipotent stromal cells

scientific article

Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses

scientific article published on 4 October 2007

Tumor-associated macrophages: effectors of angiogenesis and tumor progression.

scientific article published on 06 March 2009

Tumour Dormancy and Reawakening: Opportunities and Challenges

scientific article published on 25 November 2019

Use of macrophages to target therapeutic adenovirus to human prostate tumors

scientific article published on 13 January 2011

γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer

scientific article published on 01 July 2019

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