List of works - Jan Pieter Abrahams

2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks

scientific article published on 12 August 2019

3D Electron Diffraction: The Nanocrystallography Revolution

scientific article published on 19 July 2019

A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystals

scientific article

A Molecular Level Approach To Elucidate the Supramolecular Packing of Light-Harvesting Antenna Systems

scientific article published on 13 September 2018

A Novel Capturing Method for Quantification of Extra-Cellular Nanovesicles.

scientific article published in February 2017

A Straightforward and Robust Method for Introducing Human Hair as a Nucleant into High Throughput Crystallization Trials

article published in 2011

A novel approximation method of CTF amplitude correction for 3D single particle reconstruction

scientific article

A posteriori correction of camera characteristics from large image data sets

scientific article

Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector.

scientific article

Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector. Corrigendum

scientific article published on 30 October 2018

Alzheimer peptides aggregate into transient nanoglobules that nucleate fibrils

scientific article published on 29 September 2014

An efficient nanolitre-volume multi-channel device for highly viscous materials used in membrane protein crystallization

Apoptin induces tumor-specific apoptosis as a globular multimer.

scientific article published on 19 December 2002

Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA.

scientific article

Apoptin's functional N- and C-termini independently bind DNA

article

Bias reduction in phase refinement by modified interference functions: introducing the gamma correction

scientific article published in July 1997

Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways

scientific article published on 16 January 2013

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease

scientific article

Characterization of a diagnostic Fab fragment binding trimeric Lewis X

scientific article

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of chlorite dismutase: a detoxifying enzyme producing molecular oxygen.

scientific article published on 26 July 2008

Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis

scientific article published on 20 June 2016

Crystal structure of an empty capsid of turnip yellow mosaic virus

scientific article published in August 2004

Crystal structure of chlorite dismutase, a detoxifying enzyme producing molecular oxygen

scientific article

Crystallization and Preliminary X-ray Diffraction Analysis of Two Conformations of Intact Human Antithrombin

article

Crystallization and preliminary X-ray analysis of an anti-LewisX Fab fragment with and without its LewisX antigen

scientific article published on 27 June 2003

Crystallization and preliminary X-ray crystallographic studies on a Kunitz-type potato serine protease inhibitor

scientific article

Cyclic Peptides as Inhibitors of Amyloid Fibrillation

Cyclops: new modular software suite for cryo-EM.

scientific article published on 14 July 2006

Effect of reactive site loop elongation on the inhibitory activity of C1-inhibitor

scientific article

Electron crystallography with the EIGER detector.

scientific article

Electron diffraction data processing with DIALS

scientific article published on 30 May 2018

Endogenous polyamines reduce the toxicity of soluble aβ peptide aggregates associated with Alzheimer's disease

scientific article published on 2 May 2014

Heterogeneous nucleation of three-dimensional protein nanocrystals

scientific article published on 21 April 2007

Human lysozyme inhibits the in vitro aggregation of Aβ peptides, which in vivo are associated with Alzheimer's disease

scientific article published on 13 June 2013

Image Processing and Lattice Determination for Three-Dimensional Nanocrystals ⬇️

scientific article published on November 18, 2011

Imaging protein three-dimensional nanocrystals with cryo-EM.

scientific article published on 19 April 2013

Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin

scientific article

Improved diffraction of antithrombin crystals grown in microgravity

scientific article published on 01 September 1997

Inelastic scattering and solvent scattering reduce dynamical diffraction in biological crystals

scientific article published on 01 August 2019

Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with gramicidin S and engineered analogues

scientific article published on 11 November 2013

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

scientific article

Involvement of a carboxylated lysine in UV damage endonuclease

scientific article

Kirromycin drastically reduces the affinity of Escherichia coli elongation factor Tu for aminoacyl-tRNA

scientific article published on 01 July 1991

Lattice filter for processing image data of three-dimensional protein nanocrystals.

scientific article published on January 2016

Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions.

scientific article published in October 2009

Matrix methods for solving protein substructures of chlorine and sulfur from anomalous data ⬇️

scientific article published on November 21, 2001

Mechanism of Thrombin's Enigmatic Sodium Switch Revealed

scientific article published on 01 April 2003

Medipix 2 detector applied to low energy electron microscopy

scientific article published on 17 September 2009

Methods used in the structure determination of bovine mitochondrial F1 ATPase

scientific article (publication date: 1996)

Microtubule plus-end conformations and dynamics in the periphery of interphase mouse fibroblasts

scientific article published on 14 May 2008

Nano-dispensing by electrospray for biotechnology

scientific article published in September 2006

New developments in phase refinement

article

Non-chaperone proteins can inhibit aggregation and cytotoxicity of Alzheimer amyloid β peptide

scientific article published on 6 August 2014

Prediction of RNA secondary structure, including pseudoknotting, by computer simulation ⬇️

scientific article published on May 25, 1990

Prevalent conformations and subunit exchange in the biologically active apoptin protein multimer.

scientific article

Protein nano-crystallogenesis

scientific article

Protein structure determination by electron diffraction using a single three-dimensional nanocrystal.

scientific article published on 15 August 2017

Purification of Biotinylated Proteins Using Single Walled Carbon Nanotube-Streptavidin Complexes

scientific article published on 01 February 2017

Recent advances in the CRANK software suite for experimental phasing

scientific article published on 18 March 2011

Reciprocal Molecular Interactions between the Aβ Peptide Linked to Alzheimer's Disease and Insulin Linked to Diabetes Mellitus Type II.

scientific article published on 27 January 2016

Recombinant apoptin multimers kill tumor cells but are nontoxic and epitope-shielded in a normal-cell-specific fashion

scientific article published on 01 September 2003

Recycling of aborted ribosomal 50S subunit-nascent chain-tRNA complexes by the heat shock protein Hsp15

scientific article

Reducing dynamical electron scattering reveals hydrogen atoms

article published in 2019

Relevance of apoptin's integrity for its functional behavior

scientific article published on January 2005

Screening crystallisation conditions using fluorescence correlation spectroscopy

scientific article published on 26 September 2002

Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures

scientific article published on 17 December 2019

Single-walled carbon nanotubes as scaffolds to concentrate DNA for the study of DNA-protein interactions

scientific article

Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species.

scientific article

Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals

scientific article published on 01 January 2021

Structural mobility of antithrombin and its modulation by heparin

article

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

scientific article

Structure elucidation of β-mannanase: from the electron-density map to the DNA sequence

scientific article published on 01 January 2001

Structure of a post-translationally processed heterodimeric double-headed Kunitz-type serine protease inhibitor from potato ⬇️

scientific article published on June 15, 2012

Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen

scientific article published in July 2004

Structure of beta-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity

scientific article (publication date: 21 February 2003)

Structure of the E. coli signal recognition particle bound to a translating ribosome

scientific article published in Nature

Structure of the E. coli signal recognition particle bound to a translating ribosome.

scientific article published on 29 October 2006

Supramolecular architectures of molecularly thin yet robust free-standing layers

scientific article published on 22 February 2019

TYSON: robust searching, sorting, and selecting of single particles in electron micrographs.

scientific article published on January 2004

The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site

scientific article

The Aβ peptide forms non-amyloid fibrils in the presence of carbon nanotubes

The Impact of Single Amino Acid Substitutions in CD3γ on the CD3ϵγ Interaction and T-Cell Receptor–CD3 Complex Formation

scientific article published on 26 May 2006

The Max-Inf2/Lorentz Center workshop on New algorithms in macromolecular crystallography and electron microscopy

scientific article published on 20 June 2009

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage

scientific article published on 22 May 2018

The anticoagulant activation of antithrombin by heparin

scientific article published in December 1997

The crystal structure of the nucleotide-free α3β3 subcomplex of F1-ATPase from the thermophilic Bacillus PS3 is a symmetric trimer ⬇️

scientific article published on June 15, 1997

The functional integrity of the serpin domain of C1-inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant.

scientific article

The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway

scientific article published on 16 April 2014

The influence of tRNA located at the P-site on the turnover of EF-Tu·GTP on ribosomes

scientific article published on 01 July 1991

The interaction between aminoacyl-tRNA and the mutant elongation factors Tu AR and B0

scientific article published on 01 August 1990

The prospects of protein nanocrystallography

scientific article published on 21 October 2002

The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin.

scientific article

The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin

scientific article

The structure of bovine mitochondrial F1-ATPase: an example of rotary catalysis.

scientific article

The structure of the receptor-binding domain of the bacteriophage T4 short tail fibre reveals a knitted trimeric metal-binding fold

scientific article

The wild-type flagellar filament of the Firmicute Kurthia at 2.8 Å resolution in vivo

scientific article published on 18 October 2019

Ultra-small graphene oxide functionalized with polyethylenimine (PEI) for very efficient gene delivery in cell and zebrafish embryos

article

Unit-cell determination from randomly oriented electron-diffraction patterns

scientific article published on 20 June 2009

Visualization by cryo-electron microscopy of genomic RNA that binds to the protein capsid inside bacteriophage MS2.

scientific article published on September 2003

Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.

scientific article

X-Ray Crystallographic Structure Determination of Large Asymmetric Macromolecular Assemblies

scientific article published on 01 January 2003

List of works by Jan Pieter Abrahams

2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks

3D Electron Diffraction: The Nanocrystallography Revolution

A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystals

A Molecular Level Approach To Elucidate the Supramolecular Packing of Light-Harvesting Antenna Systems

A Novel Capturing Method for Quantification of Extra-Cellular Nanovesicles.

A Straightforward and Robust Method for Introducing Human Hair as a Nucleant into High Throughput Crystallization Trials

A novel approximation method of CTF amplitude correction for 3D single particle reconstruction

A posteriori correction of camera characteristics from large image data sets

Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector.

Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector. Corrigendum

Alzheimer peptides aggregate into transient nanoglobules that nucleate fibrils

An efficient nanolitre-volume multi-channel device for highly viscous materials used in membrane protein crystallization

Apoptin induces tumor-specific apoptosis as a globular multimer.

Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA.

Apoptin's functional N- and C-termini independently bind DNA

Bias reduction in phase refinement by modified interference functions: introducing the gamma correction

Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease

Characterization of a diagnostic Fab fragment binding trimeric Lewis X

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of chlorite dismutase: a detoxifying enzyme producing molecular oxygen.

Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis

Crystal structure of an empty capsid of turnip yellow mosaic virus

Crystal structure of chlorite dismutase, a detoxifying enzyme producing molecular oxygen

Crystallization and Preliminary X-ray Diffraction Analysis of Two Conformations of Intact Human Antithrombin

Crystallization and preliminary X-ray analysis of an anti-LewisX Fab fragment with and without its LewisX antigen

Crystallization and preliminary X-ray crystallographic studies on a Kunitz-type potato serine protease inhibitor

Cyclic Peptides as Inhibitors of Amyloid Fibrillation

Cyclops: new modular software suite for cryo-EM.

Effect of reactive site loop elongation on the inhibitory activity of C1-inhibitor

Electron crystallography with the EIGER detector.

Electron diffraction data processing with DIALS

Endogenous polyamines reduce the toxicity of soluble aβ peptide aggregates associated with Alzheimer's disease

Heterogeneous nucleation of three-dimensional protein nanocrystals

Human lysozyme inhibits the in vitro aggregation of Aβ peptides, which in vivo are associated with Alzheimer's disease

Image Processing and Lattice Determination for Three-Dimensional Nanocrystals ⬇️

Imaging protein three-dimensional nanocrystals with cryo-EM.

Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin

Improved diffraction of antithrombin crystals grown in microgravity

Inelastic scattering and solvent scattering reduce dynamical diffraction in biological crystals

Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with gramicidin S and engineered analogues

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

Involvement of a carboxylated lysine in UV damage endonuclease

Kirromycin drastically reduces the affinity of Escherichia coli elongation factor Tu for aminoacyl-tRNA

Lattice filter for processing image data of three-dimensional protein nanocrystals.

Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions.

Matrix methods for solving protein substructures of chlorine and sulfur from anomalous data ⬇️

Mechanism of Thrombin's Enigmatic Sodium Switch Revealed

Medipix 2 detector applied to low energy electron microscopy

Methods used in the structure determination of bovine mitochondrial F1 ATPase

Microtubule plus-end conformations and dynamics in the periphery of interphase mouse fibroblasts

Nano-dispensing by electrospray for biotechnology

New developments in phase refinement

Non-chaperone proteins can inhibit aggregation and cytotoxicity of Alzheimer amyloid β peptide

Prediction of RNA secondary structure, including pseudoknotting, by computer simulation ⬇️

Prevalent conformations and subunit exchange in the biologically active apoptin protein multimer.

Protein nano-crystallogenesis

Protein structure determination by electron diffraction using a single three-dimensional nanocrystal.

Purification of Biotinylated Proteins Using Single Walled Carbon Nanotube-Streptavidin Complexes

Recent advances in the CRANK software suite for experimental phasing

Reciprocal Molecular Interactions between the Aβ Peptide Linked to Alzheimer's Disease and Insulin Linked to Diabetes Mellitus Type II.

Recombinant apoptin multimers kill tumor cells but are nontoxic and epitope-shielded in a normal-cell-specific fashion

Recycling of aborted ribosomal 50S subunit-nascent chain-tRNA complexes by the heat shock protein Hsp15

Reducing dynamical electron scattering reveals hydrogen atoms

Relevance of apoptin's integrity for its functional behavior

Screening crystallisation conditions using fluorescence correlation spectroscopy

Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures

Single-walled carbon nanotubes as scaffolds to concentrate DNA for the study of DNA-protein interactions

Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species.

Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals

Structural mobility of antithrombin and its modulation by heparin

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

Structure elucidation of β-mannanase: from the electron-density map to the DNA sequence

Structure of a post-translationally processed heterodimeric double-headed Kunitz-type serine protease inhibitor from potato ⬇️

Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen

Structure of beta-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity

Structure of the E. coli signal recognition particle bound to a translating ribosome

Structure of the E. coli signal recognition particle bound to a translating ribosome.

Supramolecular architectures of molecularly thin yet robust free-standing layers

TYSON: robust searching, sorting, and selecting of single particles in electron micrographs.