List of works - Irina Caminschi

Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

scientific article published on 14 January 2015

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

article

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes.

scientific article published on 12 December 2016

Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection.

scientific article

Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger".

scientific article published in October 2005

Autophagy for Better or Worse during Infectious Diseases ⬇️

scientific article published on July 19, 2013

Boosting antibody responses by targeting antigens to dendritic cells

scientific article published on 06 December 2011

CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen

scientific article

CD14 is not involved in the uptake of synthetic CpG oligonucleotides

scientific article

CD8 T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

article

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

article

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

scientific article

Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination.

scientific article published on 4 February 2015

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

scientific article published on 6 April 2009

Cytokine gene therapy of mesothelioma. Immune and antitumor effects of transfected interleukin-12.

scientific article published in September 1999

Cytokine gene therapy or infusion as treatment for solid human cancer.

scientific article

DEC-205 is a cell surface receptor for CpG oligonucleotides

scientific article

DEC-205 is a cell surface receptor for CpG oligonucleotides

article

DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats.

scientific article

Dendritic Cell Subsets and Immune Regulation

Differential Migration of Epidermal and Dermal Dendritic Cells during Skin Infection

scientific article published on 01 March 2009

Differential effect of CD8(+) and CD8(-) dendritic cells in the stimulation of secondary CD4(+) T cells.

scientific article published on April 2001

Enhancing immune responses by targeting antigen to DC.

scientific article published in April 2009

Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells

scientific article published on 6 November 2017

Erratum: The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

article

Evidence that multiple defects in murine DC-SIGN inhibit a functional interaction with pathogens

scientific article published on 17 November 2005

Evolution of B cell responses to Clec9A-targeted antigen

scientific article published on 11 October 2013

FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo.

scientific article published on 22 January 2014

Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN

scientific journal article

Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE

scientific article (publication date: February 2006)

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

scientific article published on 01 June 2020

IL-12p40/IL-10 Producing preCD8α/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection

scientific article

Improving vaccines by targeting antigens to dendritic cells

scientific article published on February 2009

Interleukin-12 induces an effective antitumor response in malignant mesothelioma.

scientific article published on November 1998

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

scientific article published on 17 September 2016

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections

scientific article

Modulation of monosodium urate crystal-induced responses in neutrophils by the myeloid inhibitory C-type lectin-like receptor: potential therapeutic implications

scientific article

Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations

scientific article published in October 2001

Molecular cloning of a C-type lectin superfamily protein differentially expressed by CD8alpha(-) splenic dendritic cells

scientific journal article

Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus

scientific article

New generation of dendritic cell vaccines

scientific article published on 04 January 2013

Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells

scientific article published on 12 October 2006

Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells

scientific article

Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly

scientific article published on 18 April 2013

Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy.

scientific article

Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells

scientific article published in July 2006

Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response

scientific article

Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall

scientific article published on 22 June 2015

Targeting CLEC9A delivers antigen to human CD141(+) DC for CD4(+) and CD8(+)T cell recognition

scientific article published on 19 May 2016

Targeting Dendritic Cells in vivo for Cancer Therapy

scientific article published on 7 February 2012

Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation

scientific article published on 06 February 2013

Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype

scientific article published on 15 June 2011

Targeting the Gut Vascular Endothelium Induces Gut Effector CD8 T Cell Responses Via Cross-Presentation by Dendritic Cells

article

The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection.

scientific article published on 15 February 2017

The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

article

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

scientific journal article

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments

scientific article

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

scientific article published on 30 July 2008

Vaccines

c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.

scientific article

List of works by Irina Caminschi

Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes.

Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection.

Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger".

Autophagy for Better or Worse during Infectious Diseases ⬇️

Boosting antibody responses by targeting antigens to dendritic cells

CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen

CD14 is not involved in the uptake of synthetic CpG oligonucleotides

CD8 T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination.

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

Cytokine gene therapy of mesothelioma. Immune and antitumor effects of transfected interleukin-12.

Cytokine gene therapy or infusion as treatment for solid human cancer.

DEC-205 is a cell surface receptor for CpG oligonucleotides

DEC-205 is a cell surface receptor for CpG oligonucleotides

DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats.

Dendritic Cell Subsets and Immune Regulation

Differential Migration of Epidermal and Dermal Dendritic Cells during Skin Infection

Differential effect of CD8(+) and CD8(-) dendritic cells in the stimulation of secondary CD4(+) T cells.

Enhancing immune responses by targeting antigen to DC.

Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells

Erratum: The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

Evidence that multiple defects in murine DC-SIGN inhibit a functional interaction with pathogens

Evolution of B cell responses to Clec9A-targeted antigen

FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo.

Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN

Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

IL-12p40/IL-10 Producing preCD8α/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection

Improving vaccines by targeting antigens to dendritic cells

Interleukin-12 induces an effective antitumor response in malignant mesothelioma.

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections

Modulation of monosodium urate crystal-induced responses in neutrophils by the myeloid inhibitory C-type lectin-like receptor: potential therapeutic implications

Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations

Molecular cloning of a C-type lectin superfamily protein differentially expressed by CD8alpha(-) splenic dendritic cells

Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus

New generation of dendritic cell vaccines

Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells

Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells

Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly

Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy.

Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells

Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response

Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall

Targeting CLEC9A delivers antigen to human CD141(+) DC for CD4(+) and CD8(+)T cell recognition

Targeting Dendritic Cells in vivo for Cancer Therapy

Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation

Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype

Targeting the Gut Vascular Endothelium Induces Gut Effector CD8 T Cell Responses Via Cross-Presentation by Dendritic Cells

The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection.

The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

Vaccines

c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.