List of works - Klaus Bønnelykke

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Childhood asthma after bacterial colonization of the airway in neonates

scientific article published in October 2007

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age.

scientific article published on 22 July 2011

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

scientific article

Rhinovirus wheezing illness and genetic risk of childhood-onset asthma

scientific article published on 27 March 2013

Variants of DENND1B associated with asthma in children

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study

scientific article

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

scientific article

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Cesarean Section and Chronic Immune Disorders

scientific article published on December 1, 2014

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

scientific article

Interaction between Asthma and Lung Function Growth in Early Life

scientific article published on March 29, 2012

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

scientific article published on 10 September 2015

Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure

scientific article published in June 2008

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Use of antibiotics during pregnancy increases the risk of asthma in early childhood

scientific article published on 6 November 2012

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

scientific article published on 21 November 2008

Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial

scientific article published on January 2016

Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring

scientific article

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

scientific article published on 22 December 2017

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Maturation of the gut microbiome and risk of asthma in childhood

scientific article published on 10 January 2018

Association between respiratory infections in early life and later asthma is independent of virus type

scientific article published on 21 April 2015

Long-term studies of the natural history of asthma in childhood

scientific article published on August 1, 2010

Coarse and fine particles but not ultrafine particles in urban air trigger hospital admission for asthma in children

scientific article published on 9 December 2011

Long-term exposure to air pollution and asthma hospitalisations in older adults: a cohort study

scientific article (publication date: 2 September 2011)

Cord blood 25(OH)-vitamin D deficiency and childhood asthma, allergy and eczema: the COPSAC2000 birth cohort study

scientific article

Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial

scientific article published on 15 December 2015

Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source

scientific article

A novel common variant in DCST2 is associated with length in early life and height in adulthood

scientific article published on 3 October 2014

Antibiotic use during pregnancy alters the commensal vaginal microbiota.

scientific article

Increased risk of eczema but reduced risk of early wheezy disorder from exclusive breast-feeding in high-risk infants

Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy

scientific article published on 10 November 2011

17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry

article

Deep phenotyping of the unselected COPSAC2010 birth cohort study.

scientific article

Children with allergic and nonallergic rhinitis have a similar risk of asthma

scientific article published on September 1, 2010

A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid

scientific article published on 20 March 2010

The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts

scientific article

Sensitization does not develop in utero

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

scientific article

Leveraging gene-environment interactions and endotypes for asthma gene discovery

scientific article published on March 1, 2016

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

scientific article published in January 2018

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

scientific article published on July 24, 2014

Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials

scientific article published on 27 October 2017

Cesarean section changes neonatal gut colonization

scientific article published on April 1, 2016

List of works by Klaus Bønnelykke

Genome-wide association study identifies 74 loci associated with educational attainment

Childhood asthma after bacterial colonization of the airway in neonates

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age.

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

Rhinovirus wheezing illness and genetic risk of childhood-onset asthma

Variants of DENND1B associated with asthma in children

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Genome-wide associations for birth weight and correlations with adult disease

Cesarean Section and Chronic Immune Disorders

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

Interaction between Asthma and Lung Function Growth in Early Life

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

Use of antibiotics during pregnancy increases the risk of asthma in early childhood

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial

Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring

Common variants at 12q15 and 12q24 are associated with infant head circumference

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Maturation of the gut microbiome and risk of asthma in childhood

Association between respiratory infections in early life and later asthma is independent of virus type

Long-term studies of the natural history of asthma in childhood

Coarse and fine particles but not ultrafine particles in urban air trigger hospital admission for asthma in children

Long-term exposure to air pollution and asthma hospitalisations in older adults: a cohort study

Cord blood 25(OH)-vitamin D deficiency and childhood asthma, allergy and eczema: the COPSAC2000 birth cohort study

Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial

Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source

A novel common variant in DCST2 is associated with length in early life and height in adulthood

Antibiotic use during pregnancy alters the commensal vaginal microbiota.

Increased risk of eczema but reduced risk of early wheezy disorder from exclusive breast-feeding in high-risk infants

Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy

17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry

Deep phenotyping of the unselected COPSAC2010 birth cohort study.

Children with allergic and nonallergic rhinitis have a similar risk of asthma

A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid

The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts

Sensitization does not develop in utero

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

Leveraging gene-environment interactions and endotypes for asthma gene discovery

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials

Cesarean section changes neonatal gut colonization

Endotyping early childhood asthma by quantitative symptom assessment

Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations