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List of works by Hélène Merle-Béral

14q deletions are associated with trisomy 12,NOTCH1mutations and unmutatedIGHVgenes in chronic lymphocytic leukemia and small lymphocytic lymphoma

scientific article published on 12 April 2014

A Multicentric Study of 41 Cases of B-Prolymphocytic Leukemia: Two Evolutive Forms: The Groupe Français d'Hématologie Cellulaire

scientific article published on 01 September 2001

A Scoring System for the Classification of CD5- B CLL versus CD5+ B CLL and B PLL

A T chronic lymphocytic leukemia with large granular lymphocytes phenotype and functions of leukemic cells under in vitro treatment by differentiation inducers

scientific article published on 01 April 1987

A comparison of the sensitivity of flow cytometry and bone marrow biopsy in the detection of minimal residual disease in chronic lymphocytic leukemia

scientific article published on 01 June 2006

A further characterization of B-CLL lymphocytes: phenotypic and functional studies

scientific article published on 01 January 1990

A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

scientific article published on 27 March 2014

A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines.

scientific article

A single-center study of 11 patients with intraocular lymphoma treated with conventional chemotherapy followed by high-dose chemotherapy and autologous bone marrow transplantation in 5 cases

scientific article published in October 1996

A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia

scientific article published on 20 May 2011

AIDS-Related Primary Lymphoma of the Pleural Cavity

article

APRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival

scientific article published on 01 September 2007

Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells

scientific article published on 22 October 2009

Absence of microsatellite instability in human chronic lymphocytic leukaemia B cells

Acquired initiating mutations in early hematopoietic cells of CLL patients

scientific article

Adult T-cell leukemia/lymphoma revealed by a surgically cured cardiac valve lymphomatous involvement in an Iranian woman: clinical, immunopathological and viromolecular studies.

scientific article published in November 1993

Analysis of CD16+CD56dim NK cells from CLL patients: evidence supporting a therapeutic strategy with optimized anti-CD20 monoclonal antibodies

article

Analysis of VH gene expression in CD5+ and CD5- B-cell chronic lymphocytic leukemia.

scientific article published in November 1995

Analysis ofBCR-ABL mRNA in chronic myelogenous leukemia patients and identification of a newBCR-related sequence in human DNA

article

Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody ublituximab on chronic lymphocytic leukemia cells with the 17p deletion

Antiviral therapy is associated with a better survival in patients with hepatitis C virus and B-cell non-Hodgkin lymphomas, ANRS HC-13 lympho-C study

scientific article

Apoptosis in blood diseases. Review new data.

scientific article published on July 1996

Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays; an ERIC-wide approach

article published in 2014

Autologous hematopoietic stem cell transplantation as salvage treatment for advanced B cell chronic lymphocytic leukemia

scientific article published on 01 November 1998

Autologous stem cell transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter, randomized, controlled trial from the SFGM-TC and GFLLC

scientific article published on 15 March 2011

Automation in hematologic cytology

scientific article published on January 1993

B-cell chronic lymphocytic leukaemia: a polymorphic family unified by genomic features

scientific article

B8.7 Antigen expression on B-CLL cells and its relationship to the LMW-BCGF responsiveness

scientific article published on 01 January 1990

Basket cells or shadow cells of Gumprecht: a scanning electron microscope study, and the correlation between percentages of basket cells, and cells with altered chromatin structure (dense cells), in chronic lymphocytic leukemia.

scientific article published on January 1993

Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia

scientific article published in November 2003

Biological diagnosis of primary intraocular lymphoma

scientific article published in February 2004

Burkitt-type acute leukemia in a patient with B-prolymphocytic leukemia: evidence for a common origin

CD1 expression on B-CLL lymphocytes

scientific article published on 01 February 1989

CD1c is not a feature of mixed-cell type but of a typical form of chronic lymphocytic leukaemia

scientific article published on February 1, 1992

CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans

scientific article

Caspase-independent type III PCD: a new means to modulate cell death in chronic lymphocytic leukemia

scientific article

Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton

scientific article published on 10 March 2009

Cell-mediated autoimmunity in paraneoplastic neurological syndromes with anti-Hu antibodies.

scientific article published in February 1999

Changes in microrheology of acute promyelocytic leukemia cells during all-trans retinoic acid (ATRA) differentiation therapy: a mechanism for ATRA-induced hyperleukocytosis?

scientific article published on September 1995

Characterization of normal human bone marrow by flow cytometry

scientific article published on 01 January 1991

Characterization of vitreous B-cell infiltrates in patients with primary ocular lymphoma, using CDR3 size polymorphism analysis of antibody transcripts

scientific article

Chronic lymphocytic leukaemia cells are efficiently killed by an anti-CD20 monoclonal antibody selected for improved engagement of FcgammaRIIIA/CD16.

scientific article

Chronic lymphocytic lymphoma and multiple myeloma in a patient infected with human herpesvirus 8 (HHV-8)

scholarly article by Pierre Tattevin et al published 26 September 2002 in American Journal of Hematology

Chronic myeloid leukemia with variant e19a2 BCR-ABL1 fusion transcript: interest of the molecular identification at diagnosis for minimal residual disease follow-up

scientific article

Cleaved lymphocytes in chronic lymphocytic leukemia: a detailed retrospective analysis of diagnostic features

scientific article

Clonal B cell populations in the blood and liver of patients with chronic hepatitis C virus infection

scientific article published in November 2004

Colonic polyposis as sole manifestation of chronic lymphocytic leukemia

scientific article published on 01 April 1994

Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males

scientific article

Concomitant telomere shortening, acquisition of multiple chromosomal aberrations and in vitro resistance to apoptosis in a single case of progressive CLL

article published in 2011

Cytokine profile in human eyes: contribution of a new cytokine combination for differential diagnosis between intraocular lymphoma or uveitis

scientific article

Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications

Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes

article

Detection of minimal residual disease in B Chronic Lymphocytic Leukemia (CLL)

scientific article published on 01 February 1999

Diagnostic and prognostic significance of myelomonocytic cell surface antigens in acute myeloid leukaemia.

scientific article

Drp1 mediates caspase-independent type III cell death in normal and leukemic cells

scientific article published on 6 August 2007

Early onset of immunoglobulin heavy chain gene rearrangements in normal human bone marrow CD34+ cells

scientific article

Endoretinal biopsy in establishing the diagnosis of uveitis: a clinicopathologic report of three cases

scientific article

Establishment and characterization of a new human erythroleukemic cell line, ERY-1.

scientific article

Evaluation of the performance of Spectrum III

scientific article published on 01 January 1985

Expression and proliferative effect of hemokinin-1 in human B-cells

scientific article published on 18 February 2011

Expression of CD23 by human bone marrow stromal cells

scientific article published on 01 November 1992

Expression of unmutated VH genes is a detrimental prognostic factor in chronic lymphocytic leukemia

article

Extended versus involved fields irradiation combined with MOPP chemotherapy in early clinical stages of Hodgkin's disease

Fainting after drinking a glass of whiskey-soda...

scientific article published in March 2001

Flow cytometry minimal residual disease after allogeneic transplant for chronic lymphocytic leukemia

scientific article

Functional analysis of human bone-marrow-and thymus-derived early T cells

scientific article published on February 1994

Functional assessment of p53 in chronic lymphocytic leukemia

scientific article published on 25 February 2011

Functional heterogeneity of B-CLL lymphocytes: dissociated responsiveness to growth factors and distinct requirements for a first activation signal

scientific article published on 01 October 1987

Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1.

scientific article

Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages

article

High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

article by A Sainz-Perez et al published 12 January 2006 in Leukemia

High frequency of somatic mutations in the VH genes expressed in prolymphocytic leukemia.

scientific article published in November 1996

High levels of chromosome aberrations correlate with impaired in vitro radiation-induced apoptosis and DNA repair in human B-chronic lymphocytic leukaemia cells.

scientific article published in August 2002

Human NK cells display major phenotypic and functional changes over the life span

scientific article published on 10 May 2010

Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway.

scientific article published on 17 February 2005

IGHV gene insertions and deletions in chronic lymphocytic leukemia: "CLL-biased" deletions in a subset of cases with stereotyped receptors

scientific article published on July 2006

IGHV gene mutational status and LPL/ADAM29 gene expression as clinical outcome predictors in CLL patients in remission following treatment with oral fludarabine plus cyclophosphamide

scientific article

IL-10 measurement in aqueous humor for screening patients with suspicion of primary intraocular lymphoma

scientific article

IL-4 release by human leukemic and activated normal basophils.

scientific article published in August 1993

ISOLD: A New Highly Sensitive Interleukin Score for Intraocular Lymphoma Diagnosis

scientific article published on 3 March 2016

Identical abnormality of the short arm of chromosome 18 in two Philadelphia-positive chronic myelocytic leukemia patients with erythroblastic transformation, resulting in duplication of BCR-ABL1 fusion.

scientific article published in October 2002

Immunophenotypic approach to the identification and characterization of clonal plasma cells from patients with monoclonal gammopathies

scientific article published on 01 July 2004

Impaired th1/tc1 cytokine production of tumor-infiltrating lymphocytes in a model of primary intraocular B-cell lymphoma

scientific article

In vitro induction of apoptosis in chronic lymphoid leukemia B lymphocytes by theophylline: therapeutic applications

scientific article

Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

scientific article published on 01 June 1999

Induction of differentiation in human leukemic b cells by interleukin 2 alone: differential effect on the expression of μ and j chain genes

article

Inhibition of Interleukin-3-Dependent Growth of CD34+Acute Myelogenous Leukemia Cells by Recombinant Soluble CD23

scientific article published on 01 January 1991

Interleukin 4 inhibits the proliferation and promotes the maturation of human leukemic early B cells

scientific article published on 01 November 1993

Interleukin-7 and malignant T cells

scientific article published on 01 June 1993

Lack of association between human leukocyte antigens and the anti-Hu syndrome in patients with small-cell lung cancer

scientific article published on 01 February 1998

Lack of evidence of HTLV-I/II infection in T CD8 malignant or reactive lymphoproliferative disorders in France: a serological and/or molecular study of 169 cases.

scientific article published in December 1995

Leukemic CD3+ LGL share functional properties with their CD8+ CD57+ cell counterpart expanded after BMT

scientific article published on 01 February 1999

Macrophage activation syndromes

scientific article published on January 1, 1992

Maturation of acute T-lymphoblastic leukemia cells after CD2 ligation and subsequent treatment with interleukin-2

scientific article published on 01 August 1994

Maturation of human myelomonocytic leukemia cells following ligation of the low affinity receptor for IgE (Fc epsilon RII/CD23).

scientific article published on October 1993

Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release

scientific article published in August 2003

Modality treatment in adult stage I-II Hodgkin's disease with large mediastinal masses: study of 30 cases and review of the literature

scientific article published on 01 August 1993

More Than a Masquerade Syndrome: Atypical Presentations of Vitreoretinal Lymphomas

article published in 2014

Mutagenicity of non-homologous end joining DNA repair in a resistant subset of human chronic lymphocytic leukaemia B cells

scientific article published on June 2006

National standardization of ZAP-70 determination by flow cytometry: The French experience

article

New molecular markers in resistant B-CLL.

scientific article

Normal Syk protein level but abnormal tyrosine phosphorylation in B-CLL cells

scientific article published on 01 November 1997

Novel flow-cytometric analysis based on BCD5+ subpopulations for the evaluation of minimal residual disease in chronic lymphocytic leukaemia

article

Ocular Whipple's disease: therapeutic strategy and long-term follow-up

scientific article published on 13 March 2012

Ocular and central nervous system lymphoma: clinical features and diagnosis

scientific article (publication date: December 2000)

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.

scientific article

Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia

scientific article published on 24 June 2013

Partial versus productive immunoglobulin heavy locus rearrangements in chronic lymphocytic leukemia: implications for B-cell receptor stereotypy

scientific article published on 10 February 2012

Performance evaluation of the haematological analyser Cell-Dyn 3000 (Abbott)

scientific article published on 01 January 1994

Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.

scientific article published in September 1988

Plasma-cell leukemia and human herpesvirus 8 infection.

scientific article published in November 2004

Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.

scientific article published on 27 August 2015

Prognosis of Binet stage A chronic lymphocytic leukemia patients: the strength of routine parameters

scientific article published on 25 August 2010

Prognostic relevance of a scoring system based on clinical and biological parameters in early chronic lymphocytic leukemia

Prognostic relevance of a scoring system based on clinical and biological parameters in early chronic lymphocytic leukemia

scientific article published on 01 January 2000

Proposals for a Phenotypic Classification of B-Chronic Lymphocytic Leukemia, Relationship with Prognostic Factors

scientific article published on 01 January 1991

Quantification of apoptosis by the Abbott CD4000 hematology analyzer

scientific article published on 01 October 1998

Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): identification of fludarabine-sensitive and -insensitive populations

scientific article published on 28 September 2004

Retinal fluorescein, indocyanine green angiography, and optic coherence tomography in non-Hodgkin primary intraocular lymphoma

scientific article published on 25 February 2009

STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model.

scientific article published on 19 July 2013

Seven new cases of hemoglobin Camperdown alpha 2 beta 2 104(G6)Arg----Ser found in Malta, Sicily and Tunisia.

scientific article

Sex chromosome loss may represent a disease-associated clonal population in chronic lymphocytic leukemia

Sildenafil and vardenafil, types 5 and 6 phosphodiesterase inhibitors, induce caspase-dependent apoptosis of B-chronic lymphocytic leukemia cells.

scientific article published on 28 June 2002

Simple, fast method of detection apoptosis in lymphoid cells

scientific article published in June 1998

Skewed rearrangement of the VH4-21 gene during pre-B acute lymphoblastic leukemia

article

Soluble CD23 measurement by CBA: A convenient and reliable quantification method in Chronic Lymphocytic Leukemia.

scientific article

Soluble CD23 measurement by CBA: a convenient and reliable quantification method in chronic lymphocytic leukemia

scientific article

Soluble Fcγ Receptor, FcγRIIa2, is Present in Two Forms in Human Serum and is Increased in Patients: With Stage C Chronic Lymphocytic Leukemia

Specific chromosomal IG translocations have different prognoses in chronic lymphocytic leukemia

scientific article published on 15 April 2011

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

scientific article

Surrogate markers of B cell non-Hodgkin's lymphoma in patients with hepatitis C virus-related cryoglobulinaemia vasculitis

scientific article published on 27 September 2010

Synergistic action of alkylating agents and methylxanthine derivatives in the treatment of chronic lymphocytic leukemia

scientific article published on 01 December 1995

Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells

article published in 2010

The Aiolos transcription factor is up-regulated in chronic lymphocytic leukemia

The CSF IL-10 concentration is an effective diagnostic marker in immunocompetent primary CNS lymphoma and a potential prognostic biomarker in treatment-responsive patients

The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia

scientific article published on 31 March 2005

The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia

article

The optimized anti-CD20 monoclonal antibody ublituximab bypasses natural killer phenotypic features in Waldenström macroglobulinemia.

scientific article published on 31 December 2014

The resistance of B-CLL cells to DNA damage-induced apoptosis defined by DNA microarrays

scientific article

The role of CD23 on early human hematopoietic precursors

scientific article published on January 1, 1991

The role of soluble CD23 on normal and leukaemic myeloid precursor cells

scientific article published on May 1, 1992

Theophylline, a new inducer of apoptosis in B-CLL: role of cyclic nucleotides

scientific article published on 01 August 1995

Theophylline-induced B-CLL apoptosis is partly dependent on cyclic AMP production but independent of CD38 expression and endogenous IL-10 production

scientific article published on 01 January 1999

Thrombospondin-1 Mimetic Agonist Peptides Induce Selective Death in Tumor Cells: Design, Synthesis, and Structure-Activity Relationship Studies.

scientific article published on 15 August 2016

Total body irradiation in eight cases of advanced chronic lymphocytic leukamia

scientific article published on April 1, 1979

Transcriptional activation of the cardiac homeobox gene CSX1/NKX2-5 in a B-cell chronic lymphoproliferative disorder

article

Trisomy 4 associated with double minute chromosomes and MYC amplification in acute myeloblastic leukemia

scientific article

Uvéite: complication tardive d'une maladie de Whipple méconnue

scientific article published on 01 January 1995

VH gene expression in hairy cell leukaemia

article

Waldenström's macroglobulinemia harbors a unique proteome where Ku70 is severely underexpressed as compared with other B-lymphoproliferative disorders

scientific article published on 7 September 2012

What Do Chronic B Cell Malignancies Teach Us about B Cell Subsets? ⬇️

scientific article published on January 1, 1997

What does apoptosis mean in CLL?

scientific article published on October 1996

Whipple’s syndrome (uveitis, B27-negative spondylarthropathy, meningitis, and lymphadenopathy) associated with Arthrobacter sp. infection

scientific article published on 01 October 1998

[Acute leukemia and cancer induced by the combination of radiotherapy and chemotherapy]

scientific article published on 01 May 1982

[Biological aspects of chronic lymphoid leukemia]

scientific article published on 01 January 1986

[Cell Dyn 3000: technical performance and applications in hematologic pathology]

scientific article published on 01 July 1994

[Chronic lymphoid leukemia. Diagnosis, course, prognosis, treatment]

scientific article published on 01 December 1993

[Contribution of immunotyping in the diagnosis and in the prognosis of acute leukemia]

scientific article published on 01 January 1996

[Evaluation of the performance of Coulter S+II]

scientific article published on 01 January 1984

[Flow cytometry: principles and main applications]

scientific article published on 01 January 1985

[Myeloid differentiation antigens: characterization and expression in acute myeloblastic leukemias]

scientific article published on 01 January 1987

[Neurotoxicity of intrathecal methotrexate administration and external meningoencephalic irradiation in carcinomatous meningitis. Must one reconsider therapeutic technics for meningitis in acute lymphoblastic leukemias and non-Hodgkin's lymphomas?]

scientific article published on 01 January 1981

[Primary lymphoma of the central nervous system. Apropos of 8 cases]

scientific article published on 01 February 1983

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