List of works by Marc van de Vijver

A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients

scientific article

A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer ⬇️

scientific article

A conditional mouse model for malignant mesothelioma

scientific article

A distinct phenotype characterizes tumors from a putative genetic trait involving chondrosarcoma and breast cancer occurring in the same patient

scientific article published on February 2004

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

scientific article

A gene-expression signature as a predictor of survival in breast cancer

scientific article (publication date: 19 December 2002)

A mouse mammary gland involution mRNA signature identifies biological pathways potentially associated with breast cancer metastasis

scientific article published on 30 April 2009

A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study

scientific article

A simple system for grading the response of breast cancer to neoadjuvant chemotherapy.

scientific article

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

scientific article published on 23 January 2017

Additional value and potential use of the 70-gene prognosis signature in node-negative breast cancer in daily clinical practice.

scientific article published on 2 December 2009

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

scientific article published on 11 December 2006

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.

scientific article published in January 2007

Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer ⬇️

scientific article published on October 1, 1992

An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients

scientific article

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

scientific article published on August 2008

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

scholarly article

Analysis of breast cancer related gene expression using natural splines and the Cox proportional hazard model to identify prognostic associations.

scientific article published on 27 October 2009

Assessment of a HER2 scoring system for gastric cancer: results from a validation study

scientific article published on 18 April 2008

Association of C-MYC amplification with progression from the in situ to the invasive stage in C-MYC-amplified breast carcinomas.

scientific article

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

scientific article

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

scientific article published on 26 September 2016

Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcome

scientific article published on February 2003

Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer

scientific article published in May 2005

Chromogenic in situ hybridisation for the assessment of HER2 status in breast cancer: an international validation ring study

scientific article

Classification of ductal carcinoma in situ by gene expression profiling

scientific article published on January 2006

Clinical and pathological features of BRCA1 associated carcinomas in a hospital-based sample of Dutch breast cancer patients

scientific article

Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification

scientific article published on 18 August 2008

Comparison of the genetic alterations in two epithelial collision tumors of the uterine cervix. A report of two cases.

scientific article published in July 2000

Computer tomography colonography participation and yield in patients under surveillance for 6-9 mm polyps in a population-based screening trial

scientific article

Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response

scientific article published on 8 August 2009

Constructive Technology Assessment (CTA) as a tool in coverage with evidence development: the case of the 70-gene prognosis signature for breast cancer diagnostics

scientific article published on January 2009

Continuing risk of ipsilateral breast relapse after breast-conserving therapy at long-term follow-up

scientific article published on 30 January 2008

Corrigendum to “ONCOPOOL – A European database for 16,944 cases of breast cancer” [European Journal of Cancer 46 (2009) 56–71]

scholarly article published in European Journal of Cancer

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

scientific article published in October 2017

Current perspectives on HER2 testing: a review of national testing guidelines

scientific article

DNA ploidy of primary breast cancer and local recurrence after breast-conserving therapy ⬇️

scientific article published on July 1, 1991

Determination of stromal signatures in breast carcinoma

scientific article

Determining MDR1/P-glycoprotein expression in breast cancer.

scientific article published in July 2001

Differentiation-dependent expression of provirus-activated int-1 oncogene in clonal cell lines derived from a mouse mammary tumor

scientific article published on April 1990

Discordance in ERα, PR and HER2 receptor status across different distant breast cancer metastases within the same patient

scientific article published on 10 October 2013

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis

scientific article published on January 1997

ESR1 gene amplification in breast cancer: a common phenomenon?

scientific article published on 01 July 2008

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

scientific article published on 19 December 2008

Efficacy of adjuvant chemotherapy according to hormone receptor status in young patients with breast cancer: a pooled analysis

scientific article

Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer

scientific article

Emerging technologies for assessing HER2 amplification

scientific article

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior

Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract

scientific article published on 11 April 2015

Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations.

scientific article

Evolution of Screen-Detected Small (6-9 mm) Polyps After a 3-Year Surveillance Interval: Assessment of Growth With CT Colonography Compared With Histopathology.

scientific article published on 20 October 2015

Expression of Bcl-2 in node-negative breast cancer is associated with various prognostic factors, but does not predict response to one course of perioperative chemotherapy

scientific article

Expression of endoplasmic reticulum stress proteins is a candidate marker of brain metastasis in both ErbB-2+ and ErbB-2- primary breast tumors

scientific article

Expression profiling predicts outcome in breast cancer

scientific article

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

scientific article

External validation of Adjuvant! Online breast cancer prognosis tool. Prioritising recommendations for improvement

scientific article

First results of the preoperative accelerated partial breast irradiation (PAPBI) trial

scientific article published on 17 February 2015

Functional characterization of the 19q12 amplicon in grade III breast cancers

scientific article

Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas

scientific article

Gene expression profiling predicts clinical outcome of breast cancer

scientific article (publication date: 31 January 2002)

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

scientific article

Gene expression programs of human smooth muscle cells: tissue-specific differentiation and prognostic significance in breast cancers

scientific article

Gene expression signatures to predict the development of metastasis in breast cancer

scientific article published on January 2006

Gene-expression profiling and the future of adjuvant therapy

scientific article published on October 2005

Genes that mediate breast cancer metastasis to the brain

scientific article

Genetic alterations in ductal carcinoma in situ and invasive carcinoma of the breast

scientific article published on 12 March 2000

Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type

scientific article published on December 1999

Genetic regulators of large-scale transcriptional signatures in cancer

scientific article

Genomic profiling of histological special types of breast cancer.

scientific article published on 27 October 2013

HER-2 amplification is highly homogenous in gastric cancer.

scientific article

HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity

scientific article

HER2 testing in gastric cancer: a practical approach

scientific article

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

scientific article published on 13 March 2017

Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets

scientific article

Immunohistochemical categorisation of ductal carcinoma in situ of the breast

scientific article published on 27 November 2007

Impact of established prognostic factors and molecular subtype in very young breast cancer patients: pooled analysis of four EORTC randomized controlled trials

scientific article published on 24 June 2011

Improving patient care through molecular diagnostics

scientific article published in October 2004

Indicators of homologous recombination deficiency in breast cancer and association with response to neoadjuvant chemotherapy ⬇️

scientific article published on October 11, 2010

Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer

scientific article

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients

scientific article

Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome

scientific article

International network of cancer genome projects

scientific article

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article

Local recurrence after breast-conserving therapy for invasive breast cancer: high incidence in young patients and association with poor survival

scientific article published in March 1998

Local recurrence after breast-conserving therapy in relation to gene expression patterns in a large series of patients.

scientific article published on 26 May 2009

Locally advanced/inflammatory breast cancers treated with intensive epirubicin-based neoadjuvant chemotherapy: are there molecular markers in the primary tumour that predict for 5-year clinical outcome?

scientific article published in March 2003

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

scientific article

Long-term impact of the 70-gene signature on breast cancer outcome

scientific article published on 21 January 2014

Loss of Bcl-2 in invasive breast cancer is associated with high rates of cell death, but also with increased proliferative activity

scientific article

Loss of heterozygosity for defined regions on chromosomes 3, 11 and 17 in carcinomas of the uterine cervix

scientific article

Low risk of recurrence in elderly patients treated with breast conserving therapy in a single institute

scientific article published on 29 August 2016

Lung metastasis genes couple breast tumor size and metastatic spread.

scholarly article

Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients

scientific article published in November 2011

MicroRNA sequence and expression analysis in breast tumors by deep sequencing

scientific article

Microarray-based determination of estrogen receptor, progesterone receptor, and HER2 receptor status in breast cancer

scientific article

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article

Molecular profiles of progesterone receptor loss in human breast tumors

scientific article published on 19 April 2008

Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy

scientific article published on 31 October 2006

Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype

scientific article published on 13 June 2016

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations

scientific article published in August 1998

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

scientific article published on 01 November 1988

Overexpression of the HER-2 oncogene does not play a role in high-grade osteosarcomas

scientific article published on May 2004

PTEN and NEDD4 in Human Breast Carcinoma

scientific article

Papillary and neuroendocrine breast lesions: the WHO stance

scientific article published on 23 January 2015

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

article

Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial.

scientific article published on 15 November 2011

Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability

scientific article

Predicting a local recurrence after breast-conserving therapy by gene expression profiling

scientific article published on January 2006

Predicting early failure after adjuvant chemotherapy in high-risk breast cancer patients with extensive lymph node involvement

scientific article published in July 2004

Predictive factors for local recurrence in breast cancer

scientific article published on April 2012

Preoperative chemotherapy is safe in early breast cancer, even after 10 years of follow-up; clinical and translational results from the EORTC trial 10902.

scientific article published on 18 May 2008

Prevalence of serrated polyps and association with synchronous advanced neoplasia in screening colonoscopy

scientific article published on 19 November 2013

Radiation-associated breast tumors display a distinct gene expression profile

scientific article

Randomized trial of high-dose chemotherapy and hematopoietic progenitor-cell support in operable breast cancer with extensive lymph node involvement: final analysis with 7 years of follow-up

scientific article

Recent developments in the molecular genetic understanding of breast cancer

scientific article published on January 1994

Receptor conversion in distant breast cancer metastases ⬇️

scientific article

Retrospective analysis of metastatic behaviour of breast cancer subtypes

scientific article

Revealing targeted therapy for human cancer by gene module maps.

scientific article

Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma-in-situ: analysis of European Organization for Research and Treatment of Cancer Trial 10853.

scientific article

Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types

scientific article published on 4 November 2008

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

scientific article

Routine histopathology for carcinoma in cholecystectomy specimens not evidence based: a systematic review

scientific article

SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets

scientific article

Search for a gene expression signature of breast cancer local recurrence in young women

scientific article published on 23 January 2012

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

scientific article published in November 2000

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

scientific article

Standardization of HER2 testing: results of an international proficiency-testing ring study.

scientific article published on 30 March 2007

Systematic analysis of breast cancer morphology uncovers stromal features associated with survival

scientific article published in November 2011

Technology Insight: tuning into the genetic orchestra using microarrays--limitations of DNA microarrays in clinical practice

scientific article

The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age.

scientific article

The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer

scientific article published on 13 February 2009

The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis

scientific article published on 28 August 2009

The diagnosis and management of pre-invasive breast disease: pathological diagnosis--problems with existing classifications

scientific article

The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessment and patient selection for adjuvant systemic treatment

scientific article published on 21 July 2009

The landscape of cancer genes and mutational processes in breast cancer

scientific article (publication date: 16 May 2012)

The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans

scholarly article

The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer.

scientific article

The topography of mutational processes in breast cancer genomes

scientific article published on 02 May 2016

Translating the genomic architecture of breast cancer into clinical applications.

scientific article published in June 2010

Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER).

scientific article published on 26 November 2007

Using microarray analysis as a prognostic and predictive tool in oncology: focus on breast cancer and normal tissue toxicity

scientific article published on April 2008

Value and limitations of measuring HER-2 extracellular domain in the serum of breast cancer patients

scientific article published on 02 March 2009

[Preoperative needle biopsy: an improvement in palpable breast tumors with strong indications for malignancy]

scientific article published on 01 September 1996

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