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List of works by Sergio Roman-Roman

A common alternative splicing signature is associated with SF3B1 mutations in malignancies from different cell lineages.

scientific article

A genomic and transcriptomic approach for a differential diagnosis between primary and secondary ovarian carcinomas in patients with a previous history of breast cancer

scientific article

A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cells

scientific article published on 01 May 1997

A prognostic DNA signature for T1T2 node-negative breast cancer patients

scientific article published on 01 December 2010

AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism

scientific article published on 8 June 2005

Acquired resistance to endocrine treatments is associated with tumor-specific molecular changes in patient-derived luminal breast cancer xenografts.

scientific article published on 19 June 2014

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

scientific article published on 22 December 2015

Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells

scientific article published on 01 May 2001

BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop

scientific article published on October 2003

Behavior of osteoblast, adipocyte, and myoblast markers in genome-wide expression analysis of mouse calvaria primary osteoblasts in vitro

scientific article published in July 2002

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

scientific article published on 4 February 2016

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization

scientific article

Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer

scientific article published on 23 July 2012

Clinical value of R-spondins in triple-negative and metaplastic breast cancers

scientific article

Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass

scientific article published on 01 June 2006

Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma.

scientific article published on 22 May 2016

Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors.

scientific article published on 6 April 2010

Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target

scientific article

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data

scientific article published on 24 February 2015

Finding genes in the C2C12 osteogenic pathway by k-nearest-neighbor classification of expression data

scientific article

Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells

scientific article

High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients

scientific article published on 06 December 2010

Histo-genomic stratification reveals the frequent amplification/overexpression of CCNE1 and BRD4 genes in non-BRCAness high grade ovarian carcinoma

scientific article published on 29 April 2015

Identification of genes regulated during osteoblastic differentiation by genome-wide expression analysis of mouse calvaria primary osteoblasts in vitro

scientific article published in May 2003

Identification of the cleavage site involved in production of plasma soluble Fc gamma receptor type III (CD16).

scientific article published in July 1998

In vitro processing of human tumor necrosis factor-alpha.

scientific article

In-situ preferential usage of V alpha 8 T-cell receptor gene segments in a patient with bullous pemphigoid

scientific article published on 01 December 1993

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

scientific article published on August 2017

Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.

scientific article published on 7 February 2005

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

scientific article published on 20 January 2017

Involvement of small GTPases in Mycoplasma fermentans membrane lipoproteins-mediated activation of macrophages.

scientific article published on October 1999

LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development

scientific article (publication date: 16 November 2001)

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

scientific article

Molecular profiling of patient-derived breast cancer xenografts

scientific article

Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling

scientific journal article

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

scientific article published on 24 May 2016

Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts

scientific article

Patient-derived xenograft models: an emerging platform for translational cancer research

scientific article

Patient-derived xenografts recapitulate molecular features of human uveal melanomas

scientific article

Polo-like kinase 1: a potential therapeutic option in combination with conventional chemotherapy for the management of patients with triple-negative breast cancer

scientific article

Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenografts

scientific article

SF3B1 mutations are associated with alternative splicing in uveal melanoma

scientific article published on 16 July 2013

Satellite in transit metastases in rapidly fatal conjunctival melanoma: implications for angiotropism and extravascular migratory metastasis (description of a murine model for conjunctival melanoma).

scientific article published on 18 January 2016

Smad7 inhibits the survival nuclear factor kappaB and potentiates apoptosis in epithelial cells

scientific article published on 01 February 2001

Stimulating translational research: several European life science institutions put their heads together

scientific article published on 5 August 2015

TIPIN depletion leads to apoptosis in breast cancer cells

scientific article published on 9 May 2015

TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer

scientific article

The biological and prognostic significance of angiotropism in uveal melanoma

scientific article published on 27 February 2017

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma

scientific article published on 14 March 2016

Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells

scientific article

Upcoming translational challenges for uveal melanoma

scientific article

Upcoming translational challenges for uveal melanoma

scientific article published in December 2015

Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status.

scientific article published in June 2016

Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

scientific article

Wnt signaling: a key regulator of bone mass

scientific article

Wnt signalling pathway: a new target for the treatment of osteoporosis

scientific article

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