List of works - Qin Yan

5-Fluorouracil efficacy requires anti-tumor immunity triggered by cancer-cell-intrinsic STING

scientific article published on 22 February 2021

A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II

scientific article published on 01 August 1999

Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition

scientific article published on 05 November 2019

An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

scientific article published on 25 July 2016

Annotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancers

scientific article published on 03 March 2020

Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

scientific article

Cancer progression is mediated by proline catabolism in non-small cell lung cancer

scientific article published on 07 January 2020

Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis

scientific article published on 4 September 2017

Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation

scientific article

Correction to: Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

scientific article published on 01 April 2020

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

scientific article (publication date: December 2001)

Dual roles for transcription factor IIF in promoter escape by RNA polymerase II.

scientific article

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

scientific article

Epigenetic mechanisms in commonly occurring cancers.

scientific article

GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH

scientific article published on 15 August 2019

High-Throughput Deep Sequencing for Mapping Mammalian DNA Methylation

scientific article

High-throughput screening to identify inhibitors of lysine demethylases

scientific article

Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

scientific article

Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.

scientific article published on 30 May 2013

Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes

scientific journal article

Histone demethylases set the stage for cancer metastasis.

scientific article published on 30 April 2013

Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.

scientific article published on 25 May 2007

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

scientific article published on 17 October 2019

Identification of Elongin C and Skp1 sequences that determine Cullin selection

scientific article

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

scientific article published on 13 February 2013

Illumina Sequencing of Bisulfite-Converted DNA Libraries

scientific article

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.

scientific article published on 14 March 2018

KDM5 histone demethylases repress immune response via suppression of STING

scientific article published on 06 August 2018

KDM5 lysine demethylases are involved in maintenance of 3'UTR length.

scientific article

KDM5B is essential for the hyper-activation of PI3K/AKT signaling in prostate tumorigenesis

scientific article published on 31 August 2020

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements

scientific article published on 20 October 2021

Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

scientific article published on 20 February 2019

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

scientific article

MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells

scientific article published on 01 December 2021

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

scientific article (publication date: 10 August 2001)

Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells

scientific article published on 08 September 2020

Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer

scientific article published on 25 October 2018

PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth

scientific article published on 20 December 2019

Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction

scientific article published on 14 April 2020

Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway

scientific article

Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

scientific article published on 06 March 2020

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

scientific article published on 13 July 2016

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

scientific article

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

scientific article

The multiplexed CRISPR targeting platforms

scientific article published on 04 February 2018

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

scientific article published on 22 February 2007

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

scientific article published on 4 July 2011

Transcription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation Intermediates

scientific article published on 19 March 2001

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2

scientific article

List of works by Qin Yan

5-Fluorouracil efficacy requires anti-tumor immunity triggered by cancer-cell-intrinsic STING

A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II

Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition

An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

Annotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancers

Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

Cancer progression is mediated by proline catabolism in non-small cell lung cancer

Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis

Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation

Correction to: Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

Dual roles for transcription factor IIF in promoter escape by RNA polymerase II.

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

Epigenetic mechanisms in commonly occurring cancers.

GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH

High-Throughput Deep Sequencing for Mapping Mammalian DNA Methylation

High-throughput screening to identify inhibitors of lysine demethylases

Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.

Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes

Histone demethylases set the stage for cancer metastasis.

Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

Identification of Elongin C and Skp1 sequences that determine Cullin selection

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

Illumina Sequencing of Bisulfite-Converted DNA Libraries

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.

KDM5 histone demethylases repress immune response via suppression of STING

KDM5 lysine demethylases are involved in maintenance of 3'UTR length.

KDM5B is essential for the hyper-activation of PI3K/AKT signaling in prostate tumorigenesis

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements

Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells

Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer

PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth

Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction

Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway

Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

The multiplexed CRISPR targeting platforms

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

Transcription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation Intermediates

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2