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List of works by Danuta Radzioch

A Th1-associated increase in tumor necrosis factor alpha expression in the spleen correlates with resistance to blood-stage malaria in mice

scientific article

A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas

scientific article published on 20 September 2012

A murine macrophage cell line, immortalized by v-raf and v-myc oncogenes, exhibits normal macrophage functions

scientific article published on October 1987

A new era of targeting the ancient gatekeepers of the immune system: toll-like agonists in the treatment of allergic rhinitis and asthma

scientific article published on 21 May 2014

A prognostic model for development of significant liver fibrosis in HIV-hepatitis C co-infection

scientific article

Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli

scientific article published on January 2006

Acquired resistance but not innate resistance to Mycobacterium bovis bacillus Calmette-Guérin is compromised by interleukin-12 ablation

scientific article

Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis

scientific article published on 18 April 2020

AllerGen’s 8th research conference.

scientific article published on 8 December 2016

Allergic Asthma: A Summary from Genetic Basis, Mouse Studies, to Diagnosis and Treatment

scientific article published on 29 August 2016

Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV-infected patients receiving antiretroviral therapy

scientific article published on 2 June 2014

Assessment of lymphokine profiles in activated lymphocytes by semiquantitative PCR

scientific article published on 01 June 1993

Assessment of mycobacterial infection and multiplication in macrophages by polymerase chain reaction.

scientific article published in January 1993

Attenuation of MHC class II expression in macrophages infected with Mycobacterium bovis bacillus Calmette-Guérin involves class II transactivator and depends on the Nramp1 gene.

scientific article published on September 1999

Augmentation of c-fos mRNA expression by activators of protein kinase C in fresh, terminally differentiated resting macrophages

scientific article published on February 1987

Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury

scientific article

Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain

scientific article published on 12 March 2019

Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain

scientific article published on 21 August 2019

Biological importance of the two Toll-like receptors, TLR2 and TLR4, in macrophage response to infection with Candida albicans

scientific article

Brg-1 mediates the constitutive and fenretinide-induced expression of SPARC in mammary carcinoma cells via its interaction with transcription factor Sp1.

scientific article

C-Reactive Protein in Stable Cystic Fibrosis: An Additional Indicator of Clinical Disease Activity and Risk of Future Pulmonary Exacerbations

scientific article published on October 2016

Candidate markers associated with the probability of future pulmonary exacerbations in cystic fibrosis patients

scientific article

Ceramide in Cystic Fibrosis: A Potential New Target for Therapeutic Intervention ⬇️

scientific article published on December 28, 2010

Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA.

scientific article published on June 1998

Chronic Asthma–induced Airway Remodeling Is Prevented by Toll-like Receptor-7/8 Ligand S28463

scientific article published on 30 March 2007

Clearance of infection with Mycobacterium bovis BCG in mice is enhanced by treatment with S28463 (R-848), and its efficiency depends on expression of wild-type Nramp1 (resistance allele).

scientific article

Clinical outcomes associated with Staphylococcus aureus and Pseudomonas aeruginosa airway infections in adult cystic fibrosis patients

scientific article published on 21 June 2015

Clinical relevance of KRAS in human cancers

scientific article

Comparison of the susceptibilities of C57BL/6 and A/J mouse strains to Streptococcus suis serotype 2 infection

scientific article published on 23 June 2008

Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931.

scientific article published on 23 September 2016

Correction: Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers.

scientific article published on 9 January 2014

Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis ⬇️

scientific article published on 9 January 2012

Cutting Edge: STAT1 and T-bet Play Distinct Roles in Determining Outcome of Visceral Leishmaniasis Caused by Leishmania donovani

scientific article published on 01 July 2006

Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide.

scientific article

Cystic fibrosis lung disease following infection with Pseudomonas aeruginosa in Cftr knockout mice using novel non-invasive direct pulmonary infection technique

scientific article published in July 2005

Cystic fibrosis mouse models

scientific article published on 3 August 2006

Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses.

scientific article

Degradation of amyloid A precursor protein SAA by macrophage cell lines obtained from amyloid resistant and susceptible strains of mice

scientific article published on April 1997

Delayed cutaneous wound healing in mice lacking solute carrier 11a1 (formerly Nramp1): correlation with decreased expression of secretory leukocyte protease inhibitor

scientific journal article

Depletion of BAFF cytokine exacerbates infection in Pseudomonas aeruginosa infected mice

scientific article published on 07 December 2018

Deregulated balance of omega-6 and omega-3 polyunsaturated fatty acids following infection by the zoonotic pathogen Streptococcus suis

scientific article published on 18 February 2014

Differential effector and secretory functions of microglial cell lines derived from BCG-resistant and -susceptible congenic mouse strains

scientific article

Differential inhibition of IL-1 and TNF-alpha mRNA expression by agents which block second messenger pathways in murine macrophages

scientific article published on 01 November 1988

Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulat

scientific article published on 17 May 2011

Distinct pattern of lung gene expression in the Cftr-KO mice developing spontaneous lung disease compared with their littermate controls

article

Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands

article

Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers

scientific article

Does a genetically determined aggressive locomotion favour the establishment of intracellular macrophage parasites?

scientific article published on January 1993

Efficacy of Optimized Treatment Protocol Using LAU-7b Formulation against Ovalbumin (OVA) and House Dust Mite (HDM) -Induced Allergic Asthma in Atopic Hyperresponsive A/J Mice

scientific article published on 08 January 2020

Erythroid differentiation and modulation of c-myc expression induced by antineoplastic drugs in the human leukemic cell line K562.

scientific article published in September 1987

Evolution of the Immune Response to Chronic Airway Colonization with Aspergillus fumigatus Hyphae

scientific article

Expression and Function of Low-Density Lipoprotein Receptors in CD3−CD16+CD56+Cells: Effect of Interleukin 2

scientific article published on 01 January 1996

Fenretinide corrects newly found ceramide deficiency in cystic fibrosis

scientific article (publication date: 2008)

Fenretinide corrects the imbalance between omega-6 to omega-3 polyunsaturated fatty acids and inhibits macrophage inflammatory mediators via the ERK pathway.

scientific article

Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside.

scientific article

Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction

scientific article published on 31 October 2019

Fenretinide prevents inflammation and airway hyperresponsiveness in a mouse model of allergic asthma.

scientific article

Fenretinide prevents the development of osteoporosis in Cftr-KO mice.

scientific article published on 7 November 2007

Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice.

scientific article published in March 2010

Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus

scientific journal article

Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level

scientific journal article

Functionally Relevant Differences in Plasma Fatty Acid Composition and Expression of Cytotoxic and Inhibitory NK Cell Receptors between Healthy Young and Healthy Elder Adults

scientific article published on 26 November 2020

Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses

scientific article published on 02 July 2013

Generation of macrophage cell line from fresh bone marrow cells with a myc/raf recombinant retrovirus

scientific article published in October 1989

Genetic Resistance/Susceptibility to Mycobacteria: Phenotypic Expression in Bone Marrow Derived Macrophage Lines ⬇️

scientific article published on September 1, 1991

Genetic control of innate resistance to mycobacterial infections

scientific article published on March 1991

Genetic control of innate resistance to mycobacterial infections

Harvey-ras, but Not Kirsten or N-ras, Inhibits the Induction of C-fos Expression

scientific article published on 01 January 1988

Hemozoin Increases IFN-γ-Inducible Macrophage Nitric Oxide Generation Through Extracellular Signal-Regulated Kinase- and NF-κB-Dependent Pathways ⬇️

scientific article published on October 15, 2003

Heterogeneity of hematopoietic cells immortalized by v-myc/v-raf recombinant retrovirus infection of bone marrow or fetal liver

scientific article published on October 1989

Human Harvey-ras is biochemically different from Kirsten- or N-ras

scientific article published on May 1991

I-A beta gene expression regulation in macrophages derived from mice susceptible or resistant to infection with M. bovis BCG

scientific journal article

IDO-induced immunosuppressive tryptophan catabolism following primary HIV infection

Identification of novel chromosomal regions associated with airway hyperresponsiveness in recombinant congenic strains of mice

scientific article published on 15 December 2009

Immunoregulatory role of secretory leukocyte protease inhibitor in allergic asthma

scientific article

Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection

scientific article published on 23 January 2015

Impaired Ability of Cftr Knockout Mice to Control Lung Infection with Pseudomonas aeruginosa ⬇️

scientific article published on April 1, 1998

Importance of complement 3 and mannose receptors in phagocytosis of Paracoccidioides brasiliensis conidia by Nramp1 congenic macrophages lines

scientific article published on June 2006

Importance of miRNA in SARS-CoV2 infection

scientific article published on 5 December 2020

Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples.

scientific article published on 25 November 2009

Induction of nitric oxide synthase expression by lipopolysaccharide is mediated by calcium-dependent PKCα-β1 in alveolar epithelial cells

scientific article published on 17 May 2013

Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase.

scientific article

Influence of gender and interleukin-10 deficiency on the inflammatory response during lung infection with Pseudomonas aeruginosa in mice

scientific article published in November 2002

Influence of the Bcg locus on macrophage response to the dimorphic fungus Candida albicans

scientific article

Inhibition of retroviral mRNA expression in the murine macrophage cell line GG2EE by biologic response modifiers.

scientific article

Innate resistance to experimental Trypanosoma congolense infection: differences in IL-10 synthesis by macrophage cell lines from resistant and susceptible inbred mice

scientific article published on March 1999

Interaction of ionizing radiation and ZRBA1, a mixed EGFR/DNA-targeting molecule

scientific article

Interferon-alpha, -beta, and -gamma augment the levels of rRNA precursors in peritoneal macrophages but not in macrophage cell lines and fibroblasts

scientific article published on 01 August 1987

Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice

scientific article

LasR-deficient Pseudomonas aeruginosa variants increase airway epithelial mICAM-1 expression and enhance neutrophilic lung inflammation

scientific article published in March 2021

Lipoprotein lipase expression in natural killer cells and its role in their cytotoxic activity.

scientific article published on October 1994

Loss of the zona pellucida-binding protein 2 (Zpbp2) gene in mice impacts airway hypersensitivity and lung lipid metabolism in a sex-dependent fashion

scientific article published on 13 March 2018

Lung disease in mice with cystic fibrosis

scientific article published on December 1997

Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy

article

MAPKAPK-2 Signaling Is Critical for Cutaneous Wound Healing

Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions

scientific article published on 15 August 2016

Mapping of a chromosome 12 region associated with airway hyperresponsiveness in a recombinant congenic mouse strain and selection of potential candidate genes by expression and sequence variation analyses

scientific article

Mapping of novel chromosomal regions associated with atopy.

scientific article published on 3 March 2014

Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury.

scientific article

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

scientific article

Modulation of epithelial sodium channel (ENaC) expression in mouse lung infected with Pseudomonas aeruginosa

scientific article

Modulation of the allergic asthma transcriptome following resiquimod treatment.

scientific article published on 2 June 2009

Molecular genetics of inherited susceptibility to intracellular parasites

scientific article

Molecular mechanisms of natural resistance to mycobacterial infections

scientific article published on November 1, 1994

Mouse Chromosome 4 Is Associated with the Baseline and Allergic IgE Phenotypes

scientific article published on 10 July 2017

Mouse models of chronic lung infection with Pseudomonas aeruginosa: models for the study of cystic fibrosis

scientific article

Mucociliary clearance in cystic fibrosis knockout mice infected with Pseudomonas aeruginosa

scientific article published on 01 October 1997

NF-kappa B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release

scientific article published on August 2005

Natural resistance to intracellular parasites: a study by two-dimensional gel electrophoresis coupled with multivariate analysis

scientific article published on June 1998

Natural resistance to intracellular pathogens: Modulation of macrophage signal transduction related to the expression of theBcg locus ⬇️

scientific article published on April 1, 2001

New frontiers in the therapeutic management of transplant rejection

scientific article published on January 2006

Nitric oxide expression in the spleen, but not in the liver, correlates with resistance to blood-stage malaria in mice ⬇️

scientific article published on December 1, 1995

Novel pharmaceutical approaches for treating patients with cystic fibrosis.

scientific article published on January 2007

Nramp1 gene affects selective early steps in macrophage-mediated anti-cryptococcal defense

scientific article

Nuclear translocation of beta-actin is involved in transcriptional regulation during macrophage differentiation of HL-60 cells

scientific article

Pharmacological Modulation of Th17

scientific article published on 01 June 2009

Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages.

scientific article published on May 1993

Picolinic acid, a catabolite of tryptophan, as the second signal in the activation of IFN-gamma-primed macrophages

scientific article published on 01 December 1990

Polymorphisms in TOLL-like receptor genes and their roles in allergic asthma and atopy

scientific article published on January 2011

Posttranscriptional gene expression regulation in CpG-activated macrophages depends on FXR1P RNA-binding protein

scientific article published on 14 September 2007

Preferential diaphragmatic weakness during sustained Pseudomonas aeruginosa lung infection

scientific article published on 11 December 2003

Promoter Deletion Analysis Using a Dual-Luciferase Reporter System

scientific article published on 01 January 2013

Prostaglandins inhibit lipoprotein lipase gene expression in macrophages

scientific article published on 01 April 1994

Protein kinase C inhibitors block the activation of macrophages by IFN-beta but not by IFN-gamma.

scientific article

Protein tyrosine phosphatases regulate asthma development in a murine asthma model

scientific article

Quantitative assay of binding affinity of tumor associated antigen (TAA) to receptors in monitoring of lymphocyte populations generated in culture

scientific article published on 01 January 1982

RNA-binding protein HuR is required for stabilization of SLC11A1 mRNA and SLC11A1 protein expression

scientific article

Recombinant congenic strains of mice: a new tool for the genetic dissection of efficacy and toxicity of adjuvants

article

Recruitment of SWI/SNF complex is required for transcriptional activation of the SLC11A1 gene during macrophage differentiation of HL-60 cells

scientific article

Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles

scientific article published on 06 May 2009

Role of SLC11A1 (formerly NRAMP1) in regulation of signal transduction induced by Toll-like receptor 7 ligands

scientific article published on June 2006

Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death

scientific article

Role of tumor necrosis factor alpha in innate resistance to mouse pulmonary infection with Pseudomonas aeruginosa ⬇️

scientific article published on September 1, 1995

Secretory leukocyte protease inhibitor plays an important role in the regulation of allergic asthma in mice

scientific article

Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide.

scientific article published on February 1997

Selective inhibition of 28S ribosomal RNA in macrophages activated by interferon-gamma or -beta

scientific article published on 01 April 1987

Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection.

scientific article published on October 2014

Sorafenib in combination with ionizing radiation has a greater anti-tumour activity in a breast cancer model

scientific article

Structural characteristics of four human hybridoma antibodies specific for the pp65 protein of the human cytomegalovirus and their relationship to human rheumatoid factors

scientific article published in June 1994

T-enriched spleen cells in delayed-type hypersensitivity to influenza virus in mice

scientific article published in January 1985

T-helper 1-like subset selection in Mycobacterium bovis bacillus Calmette-Guérin-infected resistant and susceptible mice

scientific article published in April 1994

TLR 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates

scientific article published on 29 August 2017

TLR2-dependent recognition of Streptococcus suis is modulated by the presence of capsular polysaccharide which modifies macrophage responsiveness

scientific article published on 16 February 2007

TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway.

scientific article published on 16 December 2005

The Secretory Leukocyte Protease Inhibitor Is a Type 1 Insulin-Like Growth Factor Receptor–Regulated Protein that Protects against Liver Metastasis by Attenuating the Host Proinflammatory Response

scientific article published on 01 March 2006

The binding affinity of polyoma-tumor specific antigen (TSTA) to receptors of lymphocyte populations

scientific article published on 01 January 1981

The protective effect of fenretinide against allergic asthma

scientific article

The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide

scientific article published on 11 May 2020

Toll-like receptors, cytokines and the immunotherapeutics of asthma.

scientific article published on January 2006

Treatment of allergic asthma with Fenretinide formulation (LAU-7b) downregulates Ormdl3 expression and normalizes ceramides imbalance

scientific article published on 09 April 2020

Two distinct regions in the 3' untranslated region of tumor necrosis factor alpha mRNA form complexes with macrophage proteins

scientific article published on October 1996

ZRBA1, a Mixed EGFR/DNA Targeting Molecule, Potentiates Radiation Response Through Delayed DNA Damage Repair Process in a Triple Negative Breast Cancer Model

scientific article

[Delivery in hypoxic tumor regions of a chemotherapeutic agent encapsulated in nanoliposomes carried by magnetoaerotactic bacteria]

scientific article published on 16 March 2018

c-Src kinase is involved in the tyrosine phosphorylation and activity of SLC11A1 in differentiating macrophages.

scientific article

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