List of works by Daniel N. Wilson

A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest

scientific article published on 6 July 2016

A conserved proline triplet in Val-tRNA synthetase and the origin of elongation factor P.

scientific article published on 9 October 2014

A new system for naming ribosomal proteins

scientific article

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

scientific article

A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction

scientific article

Amythiamicin D and Related Thiopeptides as Inhibitors of the Bacterial Elongation Factor EF-Tu: Modification of the Amino Acid at Carbon Atom C2 of Ring C Dramatically Influences Activity

scientific article published on 17 September 2013

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.

scientific article published on 24 July 2017

Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins.

scientific article published in March 2011

Antimicrobial peptides target ribosomes

scientific article published in July 2015

Arginine-rhamnosylation as new strategy to activate translation elongation factor P

scientific article published on 16 February 2015

Bacterial Protein Synthesis as a Target for Antibiotic Inhibition

scientific article

Biosynthesis of the aminocyclitol subunit of hygromycin A in Streptomyces hygroscopicus NRRL 2388.

scientific article published in November 2009

Blast from the Past: Reassessing Forgotten Translation Inhibitors, Antibiotic Selectivity, and Resistance Mechanisms to Aid Drug Development.

scientific article

Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

scientific article published on 06 October 2020

Climbing to the peak of nascent-chain knowledge

scientific article published in November 2016

Context-specific action of macrolide antibiotics on the eukaryotic ribosome

scientific article published on 14 May 2021

Corrigendum: Arginine-rhamnosylation as new strategy to activate translation elongation factor P.

scientific article published in April 2015

Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution

scientific article

Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions.

scientific article published on 15 December 2016

Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution

scientific article published on 13 April 2015

Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins

scientific article

Deacylated tRNA is released from the E site upon A site occupation but before GTP is hydrolyzed by EF-Tu.

scientific article

Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea.

scientific article published on 08 December 2016

Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases

scientific article

Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding

scientific article

Dissection of the mechanism for the stringent factor RelA.

scientific article published in October 2002

Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P

scientific article published on 03 September 2013

Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity

scientific article published on 21 January 2009

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A

scientific article published on 28 May 2015

Drug sensing by the ribosome induces translational arrest via active site perturbation

scientific article published on 8 October 2014

EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.

scientific article published in February 2006

Enhanced SnapShot: Antibiotic inhibition of protein synthesis II.

scientific article

Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein

scientific article

Entropic Contribution of Elongation Factor P to Proline Positioning at the Catalytic Center of the Ribosome.

scientific article published on 18 September 2015

Erratum for Grossman et al., target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

scientific article published on September 2015

Fragments of the Nonlytic Proline-Rich Antimicrobial Peptide Bac5 Kill Escherichia coli Cells by Inhibiting Protein Synthesis.

scientific article published on 27 July 2018

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

scientific article

High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome

scientific article

Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays

scientific article

Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis

scientific article

Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly

scientific journal article

Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition

scientific article published on 01 May 2010

Knud Hermann Nierhaus 1941-2016.

scientific article published in June 2016

Less is more for leaderless mRNA translation

scientific article published in January 2009

Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome

scientific article

Localization of the trigger factor binding site on the ribosomal 50S subunit.

scientific article published in February 2003

Lys34 of translation elongation factor EF-P is hydroxylated by YfcM.

scientific article

Maintaining the ribosomal reading frame: the influence of the E site during translational regulation of release factor 2.

scientific article published in July 2004

Mechanism of ribosome rescue by alternative ribosome-rescue factor B

scientific article published on 14 August 2020

Microarray analysis of postictal transcriptional regulation of neuropeptides

scientific article published in January 2005

Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin.

scientific article

Molecular mimicry in the decoding of translational stop signals.

scientific article published on January 2003

Myticalins: A Novel Multigenic Family of Linear, Cationic Antimicrobial Peptides from Marine Mussels (Mytilus spp.).

scientific article

Nascent peptides that block protein synthesis in bacteria

scientific article published on 19 February 2013

New features of the ribosome and ribosomal inhibitors: non-enzymatic recycling, misreading and back-translocation

scientific article published on 2 May 2008

Non-hydrolyzable RNA-peptide conjugates: a powerful advance in the synthesis of mimics for 3'-peptidyl tRNA termini

scientific article published in January 2009

On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics.

scientific article

On the specificity of antibiotics targeting the large ribosomal subunit.

scientific article published on December 2011

On the use of the antibiotic chloramphenicol to target polypeptide chain mimics to the ribosomal exit tunnel

scientific article published on 14 June 2013

PSRP1 is not a ribosomal protein, but a ribosome-binding factor that is recycled by the ribosome-recycling factor (RRF) and elongation factor G (EF-G).

scientific article

Peptides in the ribosomal tunnel talk back

scientific article published on 01 February 2011

Polyamines affect diversely the antibiotic potency: insight gained from kinetic studies of the blasticidin S AND spiramycin interactions with functional ribosomes

scientific article published on 9 April 2004

Proline-rich antimicrobial peptides targeting protein synthesis.

scientific article

Protein synthesis at atomic resolution: mechanistics of translation in the light of highly resolved structures for the ribosome.

scientific article

Proteomic characterization of archaeal ribosomes reveals the presence of novel archaeal-specific ribosomal proteins

scientific article

RelBE or not to be

scientific article published on 01 April 2005

Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis

scientific article published on 27 November 2019

Repurposing tRNAs for nonsense suppression

scientific article published on 22 June 2021

Ribosomal crystallography: peptide bond formation and its inhibition

scientific article

Ribosome rescue, nearing the end.

scientific article published in February 2014

Ribosome-targeting antibiotics and mechanisms of bacterial resistance.

scientific article published on January 2014

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system

scientific article published on 01 August 2021

Shine-Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG

scholarly article

SnapShot: Antibiotic inhibition of protein synthesis I

scientific article published on 01 September 2009

Species-specific antibiotic-ribosome interactions: implications for drug development

scientific article

Stall no more at polyproline stretches with the translation elongation factors EF-P and IF-5A.

scientific article published on 29 September 2015

Structural Aspects of RbfA Action during Small Ribosomal Subunit Assembly

scientific article

Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP

scientific article published on 19 November 2020

Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.

scientific article published in November 2017

Structural Basis for Ribosome Rescue in Bacteria

scientific article

Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons

scientific article published on December 2016

Structural basis for antibiotic resistance mediated by the ABCF ATPase VmlR

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors

scientific article

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

scientific article

Structural basis for the interaction of protein S1 with the Escherichia coli ribosome.

scientific article

Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide

scientific article

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

scientific article published on 11 June 2021

Structural insight into nascent polypeptide chain-mediated translational stalling.

scientific article

Structure of <i>Escherichia coli</i> heat shock protein Hsp15 in complex with the ribosomal 50S subunit bearing peptidyl-tRNA

scientific article published in 2022

Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1

scientific article published on 03 September 2018

Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling

scientific article published on 23 April 2015

Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.

scientific article published on 3 May 2017

Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.

scientific article published on 20 January 2016

Structures of the human and Drosophila 80S ribosome

scientific article

Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome

scientific article published on 21 June 2016

Target protection as a key antibiotic resistance mechanism

scientific article published on 25 June 2020

Target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

scientific article published on 21 February 2012

Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel

scientific article published on 29 June 2020

Tetracycline antibiotics and resistance mechanisms.

scientific article published on May 2014

The ABC of Ribosome-Related Antibiotic Resistance

scientific article published on 3 May 2016

The DARC site: a database of aligned ribosomal complexes

scientific article (publication date: 2012)

The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome.

scientific article published on 22 February 2018

The E-site story: the importance of maintaining two tRNAs on the ribosome during protein synthesis.

scientific article published on December 2006

The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis

scientific article published on 16 March 2020

The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

scientific article published on 24 September 2006

The bacterial translation stress response.

scientific article

The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction.

scientific article published in November 2005

The final step of hygromycin A biosynthesis, oxidation of C-5''-dihydrohygromycin A, is linked to a putative proton gradient-dependent efflux

scientific article published on 21 September 2009

The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling

scientific article published on 30 May 2017

The how and Y of cold shock.

scientific article

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

scientific article

The oxazolidinone class of drugs find their orientation on the ribosome

scientific article published on 01 May 2007

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

scientific article

The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246

scientific article published on December 2000

The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis.

scientific article

The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis

scientific article

The structure and function of the eukaryotic ribosome

scientific article

The weird and wonderful world of bacterial ribosome regulation.

scientific article published on May 2007

Time-resolved binding of azithromycin to Escherichia coli ribosomes.

scientific article

Total Synthesis and Biological Evaluation of Paenilamicins from the Honey Bee Pathogen <i>Paenibacillus larvae</i>

scientific article published on 30 December 2021

Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A

scientific article published on 13 August 2018

Translation elongation factor EF-P alleviates ribosome stalling at polyproline stretches.

scientific article

Translation regulation via nascent polypeptide-mediated ribosome stalling

scientific article published on 04 February 2016

Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

scientific article

Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

scientific article

Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site

scientific article published on 20 August 2014

Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1

scientific article published in Nature Communications

X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit

scientific article published on 23 December 2004

Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation

scientific article published on 08 February 2021

[Ribosome recycling revisited]

scientific article published on 01 July 2006

alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

scientific article

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