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List of works by Jean-Pierre Lepoittevin

A liquid chromatography-mass spectrometric method for the determination of oak moss allergens atranol and chloroatranol in perfumes

scientific article published on 01 May 2004

Adverse cutaneous drug reaction to alendronate

scientific article published on 01 August 2007

Air oxidation of 17-hydroxycorticosteroids catalyzed by cupric acetate: formation of hemiacetal dimers

scientific article

Allergic contact cheilitis caused by polysilicone-15 (Parsol® SLX) in a lipcare balm

scientific article published on 01 February 2014

Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany

scientific article published on 14 October 2011

Alpha-methylene-gamma-butyrolactones: versatile skin bioactive natural products

scientific article published on January 2009

An immune response study of oakmoss absolute and its constituents atranol and chloroatranol

scientific article published on 25 January 2014

Are paraphenylenediamine and benzocaine relevant markers of sulfasalazine allergy?

scientific article published in January 2014

Can contact allergy to p-phenylenediamine explain the high rates of terpene hydroperoxide allergy? - An epidemiological study based on consecutive patch test results

scientific article published on June 2016

Can currently available non-animal methods detect pre and pro-haptens relevant for skin sensitization?

scientific article published on 26 August 2016

Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64.

scientific article published on May 2008

Chloroatranol, an extremely potent allergen hidden in perfumes: a dose-response elicitation study.

scientific article published in October 2003

Chronic actinic dermatitis to sesquiterpene lactones: [2+2] photoreaction toward thymidine of (+) and (-) alpha-methylene-hexahydrobenzofuranone with a cis ring junction

scientific article published on 22 January 2010

Comparison of elicitation potential of chloroatranol and atranol - 2 allergens in oak moss absolute

scientific article published on 01 April 2006

Contact Allergy-Emerging Allergens and Public Health Impact

scientific article published on 01 April 2020

Contact allergy caused by isothiazolinone derivatives: an overview of non-cosmetic and unusual cosmetic sources

scientific article published on 3 February 2017

Contact allergy to oak moss: search for sensitizing molecules using combined bioassay-guided chemical fractionation, GC-MS, and structure-activity relationship analysis.

scientific article published on 16 September 2003

Content of oak moss allergens atranol and chloroatranol in perfumes and similar products

scientific article

Covalent binding of the 13C-labeled skin sensitizers 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI) to a model peptide and glutathione

scientific article published in January 2004

Criteria for the evidence-based categorisation of skin sensitisers

scientific article

Dendritic cells as a tool for the predictive identification of skin sensitisation hazard - The report and recommendations of ECVAM workshop 51 ⬇️

journal article published in 2005

Deodorants: an experimental provocation study with hydroxycitronellal

scientific article

Deodorants: an experimental provocation study with isoeugenol.

scientific article published in May 2005

Development of a peptide reactivity assay for screening contact allergens

scientific article published on 14 July 2004

Effect of a Microemulsion System on Hapten-Peptide Reactivity Studies: Examples of Hydroxycitronellal and Citral, Fragrance Skin Sensitizers, with Glutathione ⬇️

scientific article published on September 20, 2010

Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spec

scientific article

Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergens

scientific article published on 18 July 2011

Evidence for Chemical and Cellular Reactivities of the Formaldehyde Releaser Bronopol, Independent of Formaldehyde Release ⬇️

scientific article published on November 23, 2011

Formation of methyl radicals derived from cumene hydroperoxide in reconstructed human epidermis: an EPR spin trapping confirmation by using 13C-substitution

scientific article published on 10 June 2019

Fragrance allergens linalool and limonene allylic hydroperoxides in skin allergy: mechanisms of action focusing on transcription factor Nrf2.

scientific article published on 29 September 2017

Further evaluation of quantitative structure-activity relationship models for the prediction of the skin sensitization potency of selected fragrance allergens

scientific article published on 01 February 2004

HR-MAS NMR spectroscopy of reconstructed human epidermis: potential for the in situ investigation of the chemical interactions between skin allergens and nucleophilic amino acids

scientific article published on 3 January 2013

Identification of carbon-centred radicals derived from linalyl hydroperoxide, a strong skin sensitizer: a possible route for protein modifications

scientific article published in June 2005

Immunological, chemical and clinical aspects of exposure to mixtures of contact allergens

scientific article published on 5 July 2017

In Situ Alkylation of Reconstructed Human Epidermis by Methyl Methanesulfonate: A Quantitative HRMAS NMR Chemical Reactivity Mapping

scientific article published on 16 November 2020

In Situ Metabolism of Cinnamyl Alcohol in Reconstructed Human Epidermis: New Insights into the Activation of This Fragrance Skin Sensitizer

scientific article

In chemico evaluation of prohapten skin sensitizers: behavior of 2-methoxy-4-(¹³C)methylphenol in the peroxidase peptide reactivity assay (PPRA) as an alternative to animal testing

scientific article published on 27 February 2013

Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system

scientific article published on 11 September 2009

In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue.

scientific article published on 19 January 2016

Is a low content in atranol/chloroatranol safe in oak moss-sensitized individuals?

scientific article published in February 2009

Isothiazolinones are still widely used in paints purchased in five European countries: a follow-up study.

scientific article published on 19 December 2017

Isothiazolinones in commercial products at Danish workplaces

scientific article published on 22 May 2014

Letter to the Editor Regarding the Article by Natsch et al., 2015

scientific article published on 23 October 2015

Matrix Effect of Human Reconstructed Epidermis on the Chemoselectivity of a Skin Sensitizing α-Methylene-γ-Butyrolactone: Consequences for the Development of in Chemico Alternative Methods

scientific article

Mechanistic assessment of peptide reactivity assay to predict skin allergens with Kathon CG isothiazolinones.

scientific article published in April 2009

Mechanistic insights on skin sensitization to linalool hydroperoxides: EPR evidence on radical intermediates formation in reconstructed human epidermis and 13C-NMR reactivity studies with thiol residues

scientific article published on 22 May 2020

Mechanistic studies on the lysine-induced N-formylation of 2,5-dimethyl-p-benzoquinonediimine

scientific article published on 13 July 2007

Metabolism versus chemical transformation or pro- versus prehaptens?

scientific article published on 01 February 2006

Methylisothiazolinone and benzisothiazolinone are widely used in paint: a multicentre study of paints from five European countries

scientific article

Modifications induced by chemical skin allergens on the metabolome of reconstructed human epidermis: A pilot high-resolution magic angle spinning nuclear magnetic resonance study

scientific article published on 21 November 2019

Nomenclature of metal allergens in contact dermatitis

scientific article published in July 2011

Nuclear magnetic resonance studies on covalent modification of amino acids thiol and amino residues by monofunctional aryl 13C-isocyanates, models of skin and respiratory sensitizers: transformation of thiocarbamates into urea adducts.

scientific article published in June 2009

Patch test reactions to Biobans in metalworkers are often weak and not reproducible

scientific article published in July 2002

Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products

scientific article

Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix

scientific article (publication date: April 2005)

Patch testing with hair cosmetic series in Europe: a critical review and recommendation

scientific article published on 15 June 2015

Potential of EPR spin-trapping to investigate in situ free radicals generation from skin allergens in reconstructed human epidermis: cumene hydroperoxide as proof of concept

scientific article published on 15 January 2018

Preservatives in cosmetics: reactivity of allergenic formaldehyde-releasers towards amino acids through breakdown products other than formaldehyde

scientific article

Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach

scientific article published on 30 March 2007

Reactivity of chemical sensitizers toward amino acids in cellulo plays a role in the activation of the Nrf2-ARE pathway in human monocyte dendritic cells and the THP-1 cell line.

scientific article published on 27 March 2013

Sensitization potential and potency of terpene hydroperoxides in the cocultured activation test method

scientific article published on 20 May 2019

Sensitization to p-amino aromatic compounds: Study of the covalent binding of 2,5-dimethyl-p-benzoquinonediimine to a model peptide by electrospray ionization tandem mass spectrometry

scientific article published on 11 April 2008

Studies of chemical selectivity of hapten, reactivity, and skin sensitization potency. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitizers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisot

scientific article published in May 2003

Synthesis and photocytotoxic activity of new alpha-methylene-gamma-butyrolactone-psoralen heterodimers

scientific article published on July 2004

Synthesis and reactivity toward nucleophilic amino acids of 2,5-[13C]-dimethyl-p-benzoquinonediimine

scientific article published on 01 September 2006

Synthesis of Allylic Hydroperoxides and EPR Spin-Trapping Studies on the Formation of Radicals in Iron Systems as Potential Initiators of the Sensitizing Pathway ⬇️

scientific article published on June 28, 2011

The Incorporation of Lysine into the Peroxidase Peptide Reactivity Assay for Skin Sensitization Assessments ⬇️

scientific article published on 09 May 2011

The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals Part I ⬇️

scientific article published on April 1, 2012

The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals Part II ⬇️

scientific article published on April 1, 2012

The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals Part III ⬇️

scientific article published on April 1, 2012

The use of three-dimensional similarity in assessing the risk of cross-reactivity between carbamazepine and psychotropic drugs

scientific article published on 10 January 2014

Thymoquinone as a causative allergen in nigella sativa oil contact dermatitis with cross reactivity to t-butylhydroquinone

scientific article published on 30 March 2020

Understanding the skin sensitization capacity of ascaridole: a combined study of chemical reactivity and activation of the innate immune system (dendritic cells) in the epidermal environment

scientific article published on 16 April 2019

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