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List of works by Carsten Geisler

A Response Calculus for Immobilized T Cell Receptor Ligands

scientific article published in Journal of Biological Chemistry

A highly conserved phenylalanine in the alpha, beta-T cell receptor (TCR) constant region determines the integrity of TCR/CD3 complexes.

scientific article published on September 1994

A novel BLK-induced tumor model

scientific article

A novel xenograft model of cutaneous T-cell lymphoma

scientific article published on December 2010

Activated human CD4+ T cells express transporters for both cysteine and cystine

scientific article published on 14 February 2012

Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice

scientific article published on 17 May 2012

Alloactivated HLA class II-positive T-cell lines induce IL-2 reactivity but lack accessory cell function in mixed leukocyte culture

article

Amino Acid Substitutions in the Melanoma Antigen Recognized by T Cell 1 Peptide Modulate Cytokine Responses in Melanoma-Specific T Cells

article

An enzyme-linked immunosorbent assay for autoantibodies against the nuclear protein Scl-70

scientific article published on 01 June 1985

An immune response study of oakmoss absolute and its constituents atranol and chloroatranol

scientific article published on 25 January 2014

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

scientific article published on 22 July 2019

B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with dasatinib in cutaneous T-cell lymphoma (CTCL).

scientific article published on 12 June 2014

Bacterial toxins fuel disease progression in cutaneous T-cell lymphoma

scientific article published on 14 August 2013

Bi-phasic Effect of Interferon (IFN)-α

scientific article published in Journal of Biological Chemistry

Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes

scientific article published on 01 January 1993

Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells

scientific article

CD4(+) T cells producing interleukin (IL)-17, IL-22 and interferon-γ are major effector T cells in nickel allergy

scientific article published in June 2013

COX-2 is a novel target in therapy of mycosis fungoides.

scientific article published on 30 September 2010

COX-2-dependent PGE(2) acts as a growth factor in mycosis fungoides (MF).

scientific article published on 29 April 2010

Cellular and Molecular Characteristics of Transformed T Cells from an Antigen-Specific T-Cell Line ⬇️

scientific article published on May 1, 1990

Cellular dynamics in the draining lymph nodes during sensitization and elicitation phases of contact hypersensitivity

scientific article published in November 2007

Ceramide-Induced TCR Up-Regulation

scientific article published on 01 September 2000

Characterization and expression of the human T cell receptor-T3 complex by monoclonal antibody F101.01.

scientific article

Characterization of T cell receptor assembly and expression in a Ti gamma delta-positive cell line.

scientific article published on February 1993

Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha.

scientific article

Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

scientific article published on May 2001

Constitutive and ligand-induced TCR degradation.

scientific article published in July 2004

Consumer available permanent hair dye products cause major allergic immune activation in an animal model

scientific article published on 20 July 2009

Cross-reactivity between methylisothiazolinone, octylisothiazolinone and benzisothiazolinone using a modified local lymph node assay

scientific article published on 25 June 2016

Cytokine Profile in Patients with Aseptic Loosening of Total Hip Replacements and Its Relation to Metal Release and Metal Allergy

scientific article published on 20 August 2019

Deficient SOCS3 and SHP-1 expression in psoriatic T cells

scientific article

Detection of local inflammation induced by repeated exposure to contact allergens by use of IVIS SpectrumCT analyses

Development of interleukin-17-producing Vγ2+ γδ T cells is reduced by ICOS signaling in the thymus

scientific article published on 29 March 2016

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

scientific article

Differences between Primed Allogeneic T-Cell Responses and the Primary Mixed Leucocyte Reaction

article

Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma

scientific article published on 07 April 2009

Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients.

scientific article

Elucidating the role of interleukin-17F in cutaneous T-cell lymphoma

scientific article published on 25 June 2013

Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

scientific article published on March 2002

Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergens

scientific article published on 18 July 2011

Epicutaneous exposure to nickel induces nickel allergy in mice via a MyD88-dependent and interleukin-1-dependent pathway

scholarly article by Marie T. Vennegaard et al published 18 July 2014 in Contact Dermatitis

Epidermal filaggrin deficiency mediates increased systemic T-helper 17 immune response

article

Failure to Synthesize the Human T-Cell CD3-zeta Chain and Its Consequence for the T-Cell Receptor-CD3 Complex Expression

Fine-tuning of T-cell development by the CD3γ di-leucine-based TCR-sorting motif.

scientific article published on 28 April 2015

Fractionation of T cell subsets on Ig anti-Ig columns: Isolation of helper T cells from nonresponder mice, demonstration of antigen-specific T suppressor cells, and selection of CD-3 negative variants of Jurkat T cells

scientific article published on 01 April 1989

Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a

scientific article

Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis

scientific article published on September 2015

IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.

scientific article

IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF).

scientific article

IL-17A- and IFNγ-Producing T Cells in Healthy Skin

scientific article published in April 2016

IL-1β-dependent activation of dendritic epidermal T cells in contact hypersensitivity

scientific article

IL-2 induces beta2-integrin adhesion via a wortmannin/LY294002-sensitive, rapamycin-resistant pathway. Phosphorylation of a 125-kilodalton protein correlates with induction of adhesion, but not mitogenesis

scientific article published on 01 December 1996

IL-23 and T(H)17-mediated inflammation in human allergic contact dermatitis

scientific article published on 4 November 2008

Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial

scientific article published on 29 January 2018

Identification of alphabeta and gammadelta T Cell Receptor-Positive Cells

article

Immune responses to hair dyes containing toluene-2,5-diamine

article

Immunological, chemical and clinical aspects of exposure to mixtures of contact allergens

scientific article published on 5 July 2017

In vitro production and characterization of partly assembled human CD3 complexes.

scientific article

Increase in Vitamin D but not Regulatory T Cells following Ultraviolet B Phototherapy of Patients with Atopic Dermatitis

scientific article published on 01 February 2019

Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice.

scientific article

Increased Sensitivity to Interferon-α in Psoriatic T Cells

scientific article published on 01 November 2005

Increased number and frequency of group 3 innate lymphoid cells in nonlesional psoriatic skin

scientific article

Increased prevalence of lymphoid tissue inducer cells in the cerebrospinal fluid of patients with early multiple sclerosis

scientific article published on 9 October 2015

Induction of CD3 delta epsilon omega by phorbol 12-myristate 13-acetate.

scientific article

Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.

scientific article published on September 1999

Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro.

scientific article published on 19 May 2015

Interleukin-2 induces β2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB) ⬇️

scientific article published on June 9, 1998

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin.

scientific article

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

scientific article published on 12 May 2015

Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

scientific article published in August 1998

Ligand-Induced TCR Down-Regulation Is Not Dependent on Constitutive TCR Cycling

scientific article published on 01 June 2002

Low SATB1 Expression Promotes IL-5 and IL-9 Expression in Sézary Syndrome

scientific article published on 26 August 2019

MHC class II ligation induces CD58 (LFA-3)-mediated adhesion in human T cells.

scientific article published on January 1998

MID2 can substitute for MID1 and control exocytosis of lytic granules in cytotoxic T cells

Malignant T cells activate endothelial cells via IL-17 F.

scientific article published on 21 July 2017

Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma

scientific article

Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome.

scientific article published on 4 September 2008

Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway

scientific article published on 24 February 2011

Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression

scientific article published on September 2004

Mechanisms behind Functional Avidity Maturation in T Cells ⬇️

scientific article published on April 26, 2012

Mice with epidermal filaggrin deficiency show increased immune reactivity to nickel

scientific article published on 13 November 2018

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

scientific article published on December 2014

Midline 1 controls polarization and migration of murine cytotoxic T cells

scientific article

Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells

scientific article

Monocyte functions in diabetes mellitus

scientific article published on 01 February 1982

NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity

scientific article

Nickel acts as an adjuvant during cobalt sensitization

scientific article

No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG.

scientific article published on 29 January 2018

Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

scientific article published on 19 December 2006

Novel primary thymic defect with T lymphocytes expressing gamma delta T cell receptor

scientific article

Optimising outcomes for patients with chronic lymphocytic leukaemia on ibrutinib therapy: European recommendations for clinical practice.

scientific article published on 9 January 2018

PKC-θ exists in an oxidized inactive form in naive human T cells.

scientific article

Peptides derived from self-proteins as partial agonists and antagonists of human CD8+ T-cell clones reactive to melanoma/melanocyte epitope MART1(27-35).

scientific article

Phenotypical and Functional Characterization of Double-Negative (CD4-CD8-) alphabeta T-Cell Receptor Positive Cells from an Immunodeficient Patient

scientific article published on 01 November 1991

Polymorphisms of the T cell receptor CD3delta and CD3epsilon chains affect anti-CD3 antibody binding and T cell activation

scientific article published on 16 July 2010

Programmed cell death-10 enhances proliferation and protects malignant T cells from apoptosis

scientific article

Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation

scientific article published on June 2006

Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

scientific article (publication date: 31 January 2003)

Protein phosphatase 2A isotypes regulate cell surface expression of the T cell receptor

scientific article

Quantifying the energetics of cooperativity in a ternary protein complex

scientific article published in April 2002

Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8+ T cells

scientific article published on 22 November 2016

Recruitment of SHP-1 Protein Tyrosine Phosphatase and Signalling by a Chimeric T-Cell Receptor-Killer Inhibitory Receptor

scientific article published on 01 June 2000

Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.

scientific article published on July 1997

Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndrome.

scientific article published on 09 September 2011

Repeated exposure to hair dye induces regulatory T cells in mice.

scientific article published on 30 September 2010

Role of CD3 gamma in T cell receptor assembly.

scientific article published on February 1996

STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides.

scientific article published on October 2014

STAT5 induces miR-21 expression in cutaneous T cell lymphoma.

scientific article published on 18 June 2016

STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

scientific article published on 15 May 2013

Single-cell heterogeneity in Sézary syndrome

scientific article published on 01 August 2018

Special AT rich-binding1 protein (SATB1) in malignant T cells.

scientific article

Specific depletion of mature T lymphocytes from human bone marrow

scientific article

Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

article

Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

scientific article published on 17 July 2019

Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma

scientific article published on 5 January 2016

Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation.

scientific article

Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

scientific article published on 17 April 2020

Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome

scientific article published on 14 May 2020

Staphylococcus enterotoxin A modulates interleukin 15-induced signaling and mitogenesis in human T cells.

scientific article

Substoichiometric ribose methylations in spliceosomal snRNAs.

scientific article published on 19 October 2017

T Cell Receptor ζ Allows Stable Expression of Receptors Containing the CD3γ Leucine-based Receptor-sorting Motif

scientific article published in Journal of Biological Chemistry

T-cell activation. V. Anti-major histocompatibility complex class I antibody-induced activation and clonal abortion in Jurkat T-leukaemic cells.

scientific article published on March 1993

T-cell receptor downregulation by ceramide-induced caspase activation and cleavage of the zeta chain.

scientific article

TCR alpha beta chains associate with the plasma membrane independently of CD3 and TCR zeta chains in murine primary T cells

article

TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

scientific article published on September 2003

TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections

scientific article published on 27 May 2011

TCR down-regulation controls T cell homeostasis.

scientific article published in October 2009

TCR down-regulation controls virus-specific CD8+ T cell responses

scientific article published in December 2008

TCR trafficking in resting and stimulated T cells

scientific article published on January 2004

THE ROLE OF CASPASE 3 AND BclxLIN THE ACTION OF INTERLEUKIN 7 (IL-7): A SURVIVAL FACTOR IN ACTIVATED HUMAN T CELLS

The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

scientific article

The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma

scientific article published on 20 January 2016

The Phosphatase Domains of CD45 are Required for Ligand Induced T-Cell Receptor Downregulation

scientific article published on 01 May 2000

The Phosphorylation State of CD3γ Influences T Cell Responsiveness and Controls T Cell Receptor Cycling

scientific article published in Journal of Biological Chemistry

The T cell receptor. Structural and functional studies.

scientific article published on September 1995

The Vitamin D Analogue Calcipotriol Reduces the Frequency of CD8+ IL-17+ T Cells in Psoriasis Lesions

scientific article published in July 2015

The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes

scientific article published on 14 February 2007

The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy

scientific article published on 22 October 2008

The effect of short-chain fatty acids on human monocyte-derived dendritic cells

scientific article published on 6 November 2015

The immunological synapse

scientific article published on 01 January 2003

The indispensable CD2-CD3 molecules: a key to T-cell differentiation and functional activation

scientific article published on July 1, 1992

The major diversification of Vγ1.1+ and Vγ2+ thymocytes in mice occurs after commitment to the γδ T-cell lineage

scientific article published on 15 July 2016

The role of innate lymphoid cells in healthy and inflamed skin

scientific article

The vitamin d receptor and T cell function

scientific article published on 18 June 2013

Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus

scientific article published on 4 December 2017

Transmembrane Signalling via HLA-DR Molecules on T Cells from a Sezary T-Cell Leukaemia Line

scientific article published on 01 December 1990

Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells

scientific article published on 13 November 2019

Two distinct pathways exist for down-regulation of the TCR.

scientific article published in July 1998

Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas

scientific article published on 29 July 2013

Vascular endothelial growth factor receptor-3 expression in mycosis fungoides

scientific article published on 28 September 2012

Vitamin D Counteracts Mycobacterium tuberculosis-Induced Cathelicidin Downregulation in Dendritic Cells and Allows Th1 Differentiation and IFNγ Secretion

scientific article published on 31 May 2017

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

scientific article

Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells

scientific article

Vitamin D-binding protein controls T cell responses to vitamin D.

scientific article

[Cholestatic hepatitis during treatment with mexiletine/lidocaine]

scientific article published on 01 April 1984

[Idiopathic orthostatic hypotension]

scientific article published on 01 January 1984

beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase

scientific article

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