Search filters

List of works by Kirsten Grønbæk

15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

scientific article published on 5 July 2016

5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies.

scientific article published on 28 March 2014

A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies

scientific article

A dual program for translation regulation in cellular proliferation and differentiation

scientific article published on September 2014

A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia

scientific article published on 13 November 2014

ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma

scientific article

Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

scientific article published on 07 September 2016

Aberrant microRNA expression in multiple myeloma

scientific article published on 05 June 2013

Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity are Linked to Clinical Responses to 5-Azacytidine

scientific article published on 03 April 2020

Advances in DNA methylation: 5-hydroxymethylcytosine revisited

scientific article published on 12 February 2011

Allele-Specific DNA Methylation Detection by Pyrosequencing®.

scientific article

Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

scientific article published on 4 November 2011

Analysis of epigenetic modifications of DNA in human cells.

scientific article published in April 2013

Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma

scientific article published on 16 February 2016

Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity.

scientific article

Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat

scientific article published in July 2014

Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities

scientific article

Clonal expansion of renal cell carcinoma-infiltrating T lymphocytes

scientific article published on 26 September 2013

Clonal hematopoiesis evolves from pre-treatment clones and stabilizes after end of chemotherapy in patients with MCL

scientific article published on 16 March 2020

Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality

scientific article published on 01 January 2020

DNA Methylation Levels of the ELMO Gene Promoter CpG Islands in Human Glioblastomas.

scientific article published on 28 February 2018

DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

scientific article published in September 2017

Deficient SOCS3 and SHP-1 expression in psoriatic T cells

scientific article

Detailed Long-Term Follow-Up of Patients Who Relapsed After the Nordic Mantle Cell Lymphoma Trials: MCL2 and MCL3

scientific article published on 21 December 2020

Development and blind clinical validation of a microRNA based predictor of response to treatment with R-CHO(E)P in DLBCL

scientific article

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

scientific article

Differential expression of miR-155 and miR-21 in tumor and stroma cells in diffuse large B-cell lymphoma

scientific article published in March 2015

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another "double hit" lymphoma with very poor outcome?

scientific article

Engaging the lysosomal compartment to combat B cell malignancies

scientific article published on 20 July 2009

Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies

scientific article published on 07 August 2018

Epigenetic changes in cancer

scientific article published on October 2007

Epigenetic changes in cancer as potential targets for prophylaxis and maintenance therapy

scientific article

Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

scientific article published on 28 July 2017

Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome

scientific article

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

scientific article published on 26 September 2016

Genetic and epigenetic alterations of the APC gene in malignant melanoma

scientific article published on July 2004

Genetic and epigenetic alterations of the reduced folate carrier in untreated diffuse large B-cell lymphoma

scientific article published on 19 November 2007

Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma

scientific article published on 05 July 2013

Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

scientific article published on 5 April 2017

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

scientific article published on 01 July 2018

Human endogenous retroviruses and their implication for immunotherapeutics of cancer

scientific article published on 01 November 2018

Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma

scientific article

Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients

scientific article

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation

scientific article published in April 2015

Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial

scientific article published on 29 January 2018

Immune Mechanisms in Myelodysplastic Syndrome

scientific article

Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in the etiology

scientific article published on 28 March 2019

Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing

scientific article published on 27 September 2013

KMT2D mutations and TP53 disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy: a FIL study

scientific article published on 19 September 2019

Kinetics of del(7q) driven leukemogenesis in a patient with JAK2 V617F and TET2 mutated chronic myeloproliferative neoplasm

scientific article published on 4 July 2013

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

scientific article published on 15 December 2011

Lenalidomide plus bendamustine-rituximab does not overcome the adverse impact of mutations in mantle cell lymphoma

scientific article published on 24 May 2018

Lenalidomide-bendamustine-rituximab in patients older than 65 years with untreated mantle cell lymphoma.

scientific article published on 27 June 2016

Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial

scientific article published on 07 March 2014

Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and Malignancy

scientific article published on 21 August 2018

Loss of PRDM11 promotes MYC-driven lymphomagenesis

scientific journal article

Mature lymphoid malignancies: origin, stem cells, and chronicity

scientific article published on 28 November 2017

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

scientific article published on December 2014

MicroRNA profiling in ocular adnexal lymphoma: a role for MYC and NFKB1 mediated dysregulation of microRNA expression in aggressive disease

scientific article published on 5 August 2013

MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors

scientific article

MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1-Infected Individuals and Are Associated With Markers of Systemic Inflammation

scientific article

MicroRNAs in mantle cell lymphoma

scientific article published on 19 February 2013

Microarray-based classification of diffuse large B-cell lymphoma

scientific article

Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years.

scientific article published on 27 December 2016

Mother-child transmission of epigenetic information by tunable polymorphic imprinting

article published in the Proceedings of the National Academy of Sciences of the United States of America

Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

scientific article

Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma

scientific article

Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters

scientific article published on 08 February 2017

Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

scientific article published on 17 October 2019

PATH-01. IDENTIFICATION OF PROGNOSTIC VARIABLES BASED ON MOLECULAR PROFILING OF LONG-TERM AND SHORT-TERM SURVIVING GLIOBLASTOMA PATIENTS

scientific article published on 6 November 2017

Predicting response to epigenetic therapy

scientific article

Publisher Correction: Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

scientific article published in Scientific Reports

SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma--a Nordic Lymphoma Group study

scientific article

Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones

scientific article

Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging

scientific article published on 04 December 2018

Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance

scientific article published on 12 November 2020

TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

scientific article published on 18 October 2021

TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

scientific article published on 22 April 2016

TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

scientific article published on 17 August 2017

The role of epigenetics in the biology of multiple myeloma.

scientific article published on 02 May 2014

Tubulointerstitial nephritis in a patient with probable autoimmune lymphoproliferative syndrome

scientific article published on July 2013

Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

scientific article published on 02 February 2016

Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas

scientific article published on 29 July 2013

Vitamin C - A new player in regulation of the cancer epigenome

scientific article published in November 2017

Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine

scientific article published on 29 August 2016

Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

scientific article published on 19 October 2015

[Paraneoplastic pancytopenia in a patient with undiagnosed lung cancer] ⬇️

scientific article published on 01 May 2014

[The cause of cytopenia of undetermined significance can often be found by using next generation sequencing] ⬇️

miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator

scientific article

miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

scientific article

p53 is associated with high-risk and pinpoints TP53 missense mutations in mantle cell lymphoma

scientific article published on 04 August 2020

Paulina is supported by:

About Paulina

Help