List of works by Murali Chintagumpala

A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo

scientific article

A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children

scientific article

A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas

scientific article published in November 2017

A phase 1 and pharmacokinetic study of enzastaurin in pediatric patients with refractory primary central nervous system tumors: a pediatric brain tumor consortium study

scientific article

A pilot study of risk-adapted radiotherapy and chemotherapy in patients with supratentorial PNET.

scientific article published on 16 September 2008

A pilot study using carboplatin, vincristine, and temozolomide in children with progressive/symptomatic low-grade glioma: a Children's Oncology Group study†

scientific article published on 7 April 2015

A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models ⬇️

scientific article published on November 12, 2010

Advances in Management of Pediatric Ependymomas

scientific article published on October 2015

Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma

scientific article published on August 2008

Anaplastic ganglioglioma arising from a Lhermitte-Duclos-like lesion. Case report

scientific article published on August 2007

Attention, processing speed, and executive functioning in pediatric brain tumor survivors treated with proton beam radiation therapy

scientific article

Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma

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Changes mimicking new leptomeningeal disease after intensity-modulated radiotherapy for medulloblastoma

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Children's Oncology Group's 2013 blueprint for research: rare tumors

scientific article published on 19 December 2012

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

scientific article

Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma

scientific article published on 17 February 2004

Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

scientific article

Comparing Intelligence Quotient Change After Treatment With Proton Versus Photon Radiation Therapy for Pediatric Brain Tumors

scientific article published on 25 January 2016

Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study

scientific article published in September 2017

Correlation of Insurance, Race, and Ethnicity with Pathologic Risk in a Controlled Retinoblastoma Cohort: A Children's Oncology Group Study

scientific article published on June 2016

DNA methylation of a novel PAK4 locus influences ototoxicity susceptibility following cisplatin and radiation therapy for pediatric embryonal tumors

scientific article published on 24 April 2017

Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors

scientific article published on 28 January 2016

EPND-05. LYSINE SPECIFIC DEMETHYLASE-1 (LSD-1) INHIBITOR SYC-836 IN COMBINATION WITH RADIATION PROLONGS ANIMAL SURVIVAL IN PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODEL OF POSTERIOR FOSSA EPENDYMOMA.

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Elevated expression of CXC chemokines in pediatric osteosarcoma patients ⬇️

scientific article published on August 30, 2010

Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average-risk or high-risk medulloblastoma

scientific article

FOXG1 dysregulation is a frequent event in medulloblastoma

scientific article published on 24 May 2007

Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma

scientific article published on January 2004

GENE-04. PEDIATRIC MALIGNANT EPITHELIOID GLIONEURONAL TUMOR: PATHOLOGICAL, CLINICAL, AND MOLECULAR CHARACTERIZATION OF A RARE AND DEADLY MALIGNANCY.

scientific article published on 31 May 2017

Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups

scientific article published on 24 October 2016

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

scientific article published on 27 March 2006

Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma

scientific article published on 14 October 2019

Glutathione S-transferase M1 and T1 polymorphisms may predict adverse effects after therapy in children with medulloblastoma

scientific article published on 24 October 2008

HG-109CONTEMPORARY SURVIVAL ENDPOINTS: AN INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA REGISTRY STUDY.

scientific article published on 30 May 2016

HG-125CD57 DEFINES A NOVEL SUB-POPULATION OF GLIOBLASTOMA STEM CELLS THAT HAVE GREATER INVASIVE POTENTIAL THAN CD133+ TUMOR CELLS.

scientific article published on 30 May 2016

HG-18NOVEL OLIG2 INHIBITOR DEMONSTRATES PRE-CLINICAL EFFICACY IN PEDIATRIC GBM.

scientific article published on 30 May 2016

HG-49A TEXAS-OKLAHOMA PEDIATRIC NEURO-ONCOLOGY CONSORTIUM (TOPNOC) PHASE 2 STUDY OF VALPROIC ACID (VPA) AND RADIATION, FOLLOWED BY MAINTENANCE VPA AND BEVACIZUMAB IN CHILDREN WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) OR HIGH-GRADE

scientific article published on 30 May 2016

HG-75CLINICAL, RADIOLOGICAL, AND HISTO-GENETIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A COLLABORATIVE REPORT FROM THE INTERNATIONAL AND SIOP-E DIPG REGISTRIES.

scientific article published on 30 May 2016

HGG-14. IDENTIFICATION OF PERSONALIZED ACTIVE AGENTS IN PEDIATRIC GLIOMAS THROUGH HIGH-THROUGHPUT DRUG SCREENING IN MATCHING PAIRS OF PATIENT DERIVED ORTHOTOPIC XENOGRAFT (PDOX) NEUROSPHERE AND MONOLAYER CELLS.

scientific article published on 31 May 2017

Identification of a plasma proteomic signature to distinguish pediatric osteosarcoma from benign osteochondroma

scientific article

Infantile fibrosarcoma: clinical and histologic responses to cytotoxic chemotherapy

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Integrated multimodal genetic testing of Ewing sarcoma--a single-institution experience

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Intensity-modulated radiotherapy (IMRT) in pediatric low-grade glioma

scientific article published on 30 April 2013

Is CMV a target in pediatric glioblastoma? Expression of CMV proteins, pp65 and IE1-72 and CMV nucleic acids in a cohort of pediatric glioblastoma patients

scientific article

LG-21IN VIVO EVOLUTION OF A NOVEL PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MOUSE MODELS OF PEDIATRIC PLEOMORPHIC XANTHOASTROCYTOMA HARBORING BRAF V600E MUTATION.

scientific article published on 30 May 2016

Lesion regression

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Local therapy to distant metastatic sites in stage IV rhabdomyosarcoma

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Low early ototoxicity rates for pediatric medulloblastoma patients treated with proton radiotherapy

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Low-level copy gain versus amplification of myc oncogenes in medulloblastoma: utility in predicting prognosis and survival. Laboratory investigation

scientific article published on January 2009

MBRS-34. MOLECULAR CHARACTERIZATION OF RECURRENT MEDULLOBLASTOMA REVEALS AN UNEXPECTEDLY HIGH INCIDENCE OF SECONDARY MALIGNANCY.

scientific article published on 22 June 2018

Maternal variation in EPHX1, a xenobiotic metabolism gene, is associated with childhood medulloblastoma: an exploratory case-parent triad study

scientific article published on 20 September 2012

Medulloblastoma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors in a child: case report

scientific article

Multimodality Treatment of Pediatric Esthesioneuroblastoma.

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Myofibroma in Infancy and Childhood

scientific article published on 5 January 2017

Neuroendocrine Tumor of the Appendix in Children

scientific article published on 14 June 2016

Obtaining informed consent for clinical tumor and germline exome sequencing of newly diagnosed childhood cancer patients

scientific article

Ototoxicity and cochlear sparing in children with medulloblastoma: Proton vs. photon radiotherapy

scientific article published on 17 January 2018

Outcome of patients with pilocytic astrocytoma and leptomeningeal dissemination

scientific article published on 06 March 2012

Outcomes and acute toxicities of proton therapy for pediatric atypical teratoid/rhabdoid tumor of the central nervous system

scientific article

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03)

scientific article published on 06 January 2021

Outcomes for pediatric patients with central nervous system germ cell tumors treated with proton therapy.

scientific article

PCM-03A COMPREHENSIVE PANEL OF PATIENT-DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODELS OF MALIGNANT PEDIATRIC BRAIN TUMORS.

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PCM-05AUTOPSY-DERIVED ORTHOTOPIC XENOGRAFT MOUSE MODELS OF TERMINAL PEDIATRIC BRAIN TUMORS.

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Pediatric Bronchial Carcinoid Tumors: A Case Series and Review of the Literature

scientific article published on 9 February 2018

Phase I and pharmacokinetic study of thalidomide with carboplatin in children with cancer.

scientific article

Phase I study of vismodegib in children with recurrent or refractory medulloblastoma: a pediatric brain tumor consortium study

scientific article published on 27 September 2013

Phase I trial of capecitabine rapidly disintegrating tablets and concomitant radiation therapy in children with newly diagnosed brainstem gliomas and high-grade gliomas

scientific article published on 16 April 2013

Pilot study of systemic and intrathecal mafosfamide followed by conformal radiation for infants with intracranial central nervous system tumors: a pediatric brain tumor consortium study (PBTC-001)

scientific article

Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma

scientific article published on 8 March 2016

Proceedings of the consensus meetings from the International Retinoblastoma Staging Working Group on the pathology guidelines for the examination of enucleated eyes and evaluation of prognostic risk factors in retinoblastoma

scientific article published on August 2009

Proton beam therapy versus conformal photon radiation therapy for childhood craniopharyngioma: multi-institutional analysis of outcomes, cyst dynamics, and toxicity

scientific article

Pulmonary Function After Treatment for Embryonal Brain Tumors on SJMB03 That Included Craniospinal Irradiation

scientific article published on 19 May 2015

RO-03OTOTOXICITY AND COCHLEAR SPARING IN CHILDREN WITH MEDULLOBLASTOMA: PROTON VS. PHOTON RADIOTHERAPY.

scientific article

RO-11DECREASED INCIDENCE OF HYPOTHYROIDISM AFTER CRANIOSPINAL IRRADIATION (CSI) WITH PROTON THERAPY (PRT) IN PATIENTS WITH MEDULLOBLASTOMA.

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Radiation-induced malignant gliomas: is there a role for reirradiation?

scientific article published on 11 February 2008

Relapsed hepatoblastoma confined to the lung is effectively treated with pulmonary metastasectomy

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Renal and hepatic tumors in the neonatal period

scientific article published on 16 May 2012

Residual intraretinal retinoblastoma after chemoreduction failure

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Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir

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Results of treatment of patients with superficial facial rhabdomyosarcomas on protocols of the Intergroup Rhabdomyosarcoma Study Group (IRSG), 1984-1997.

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Retinoblastoma: from bench to bedside

scientific article published on 7 January 2003

Retinoblastoma: review of current management

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Risk-Based Therapy for Localized Osteosarcoma.

scientific article published on 26 October 2015

Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98).

scientific article

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

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Systemic neoadjuvant chemotherapy for Group B intraocular retinoblastoma (ARET0331): A report from the Children's Oncology Group

scientific article published on 26 December 2016

TMOD-04NOVEL ORTHOTOPIC XENOGRAFT MOUSE MODELS OF TWO PEDIATRIC METASTATIC INTRACRANIAL GERMINOMAS: MODEL DEVELOPMENT AND CHARACTERIZATION.

scientific article

Targeted therapy in bone and soft tissue sarcoma in children and adolescents

scientific article published on April 2012

Topotecan is active against Wilms' tumor: results of a multi-institutional phase II study

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Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

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Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma

scientific article published on 8 September 2017

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