List of works by Piet A van Rijn

"Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence

scientific article published on 28 April 2020

A Review of Knowledge Gaps and Tools for Orbivirus Research.

scientific article published on June 2015

A common neutralizing epitope on envelope glycoprotein E2 of different pestiviruses: implications for improvement of vaccines and diagnostics for classical swine fever (CSF)?

scientific article

A cross-sectional study to determine the seroprevalence of bluetongue virus serotype 8 in sheep and goats in 2006 and 2007 in the Netherlands

scientific article

A preliminary map of epitopes on envelope glycoprotein E1 of HCV strain Brescia

scientific article

A subunit vaccine based on glycoprotein E2 of bovine virus diarrhea virus induces fetal protection in sheep against homologous challenge

scientific article published on December 1997

African horse sickness virus (AHSV) with a deletion of 77 amino acids in NS3/NS3a protein is not virulent and a safe promising AHS Disabled Infectious Single Animal (DISA) vaccine platform.

scientific article

An experimental marker vaccine and accompanying serological diagnostic test both based on envelope glycoprotein E2 of classical swine fever virus (CSFV).

scientific article published on February 1999

An experimental multivalent bovine virus diarrhea virus E2 subunit vaccine and two experimental conventionally inactivated vaccines induce partial fetal protection in sheep

scientific article published in April 1999

Analysis of the IHF binding site in the regulatory region of bacteriophage Mu ⬇️

scientific article published on June 11, 1991

Antigenically different pestivirus strains induce congenital infection in sheep: a model for bovine virus diarrhea virus vaccine efficacy studies

scientific article published on May 1996

Application of bluetongue Disabled Infectious Single Animal (DISA) vaccine for different serotypes by VP2 exchange or incorporation of chimeric VP2.

scientific article published on 13 December 2014

Assay of midazolam and brotizolam in plasma by a gas chromatographic and a radioreceptor technique.

scientific article published in December 1983

Balance of RNA sequence requirement and NS3/NS3a expression of segment 10 of orbiviruses

scientific article published on 4 December 2015

Bluetongue Disabled Infectious Single Animal (DISA) vaccine: Studies on the optimal route and dose in sheep.

scientific article

Bluetongue virus nonstructural protein NS3/NS3a is not essential for virus replication.

scientific article published on 20 January 2014

Bluetongue virus serotype 8 (BTV-8) infection reduces fertility of Dutch dairy cattle and is vertically transmitted to offspring

scientific article published on 5 August 2010

Bluetongue virus with mutated genome segment 10 to differentiate infected from vaccinated animals: a genetic DIVA approach

scientific article published on 7 September 2013

Bluetongue virus without NS3/NS3a expression is not virulent and protects against virulent bluetongue virus challenge

scientific article

Bluetongue viruses based on modified-live vaccine serotype 6 with exchanged outer shell proteins confer full protection in sheep against virulent BTV8

scientific article (publication date: 2012)

Bluetongue, Schmallenberg - what is next? Culicoides-borne viral diseases in the 21st Century

scientific article

Chimeric classical swine fever viruses containing envelope protein E(RNS) or E2 of bovine viral diarrhoea virus protect pigs against challenge with CSFV and induce a distinguishable antibody response

scientific article published on October 2000

Classical swine fever virus E(rns) deletion mutants: trans-complementation and potential use as nontransmissible, modified, live-attenuated marker vaccines

scientific article

Comparative pharmacokinetics of midazolam and loprazolam in healthy subjects after oral administration.

scientific article published in January 1986

Current and next-generation bluetongue vaccines: Requirements, strategies, and prospects for different field situations

scientific article

Detection of the European 'field' strain of bluetongue virus serotype 6 by real-time RT-PCR.

scientific article published on 8 August 2009

Development of a competitive ELISA for NS3 antibodies as DIVA test accompanying the novel Disabled Infectious Single Animal (DISA) vaccine for Bluetongue.

scientific article published on 17 September 2015

Diagnostic DIVA tests accompanying the Disabled Infectious Single Animal (DISA) vaccine platform for African horse sickness.

scientific article published on 11 May 2018

Distribution of bovine virus diarrhoea virus in tissues and white blood cells of cattle during acute infection

scientific article published on November 1998

Epidemiologic characteristics of bluetongue virus serotype 8 laboratory-confirmed outbreaks in The Netherlands in 2007 and a comparison with the situation in 2006.

scientific article published on 8 September 2009

European Bluetongue Serotype 8: Disease Threat Assessment for U.S. Sheep

scientific article

Experimental infection of small ruminants with bluetongue virus expressing Toggenburg Orbivirus proteins.

scientific article published on 18 July 2016

Experimental infection of white-tailed deer (Odocoileus virginianus) with Northern European bluetongue virus serotype 8.

scientific article published on 19 June 2013

Experimental non-transmissible marker vaccines for classical swine fever (CSF) by trans-complementation of E(rns) or E2 of CSFV.

scientific article published on February 2002

Full genome characterisation of bluetongue virus serotype 6 from the Netherlands 2008 and comparison to other field and vaccine strains

scientific article

Genetic modification of Bluetongue virus by uptake of "synthetic" genome segments.

scientific article published on 7 October 2010

High-level expression of biologically active recombinant bovine follicle stimulating hormone in a baculovirus system

scientific article published on February 1998

Identification of porcine alveolar macrophage glycoproteins involved in infection of porcine respiratory and reproductive syndrome virus

scientific article published in January 2003

Immunogenicity of recombinant VP2 proteins of all nine serotypes of African horse sickness virus.

scientific article

Improved PCR diagnostics using up-to-date in silico validation: An F-gene RT-qPCR assay for the detection of all four lineages of peste des petits ruminants virus

scientific article published on 14 September 2019

Influence of a dorsomedial hypothalamus lesion on the circadian changes in the enzyme development and activity of intestinal brushborder membranes in the rat.

scientific article published in January 1985

Monoclonal antibodies to the E2 protein of a new genotype (type 2) of bovine viral diarrhea virus define three antigenic domains involved in neutralization

scientific article published on October 1998

Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis

scientific article

Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway

scientific article published on 30 July 2019

One after the other: A novel Bluetongue virus strain related to Toggenburg virus detected in the Piedmont region (North-western Italy), extends the panel of novel atypical BTV strains

scientific article published on 2 February 2018

Oral transmission of porcine reproductive and respiratory syndrome virus by muscle of experimentally infected pigs

scientific article published in December 2003

PCR diagnostics: In silico validation by an automated tool using freely available software programs

scientific article published on 13 May 2019

Performance of clinical signs to detect bluetongue virus serotype 8 outbreaks in cattle and sheep during the 2006-epidemic in The Netherlands

scientific article published on 17 November 2007

Potential role of ticks as vectors of bluetongue virus.

scientific article

Preliminary mapping of non-conserved epitopes on envelope glycoprotein E2 of Bovine viral diarrhea virus type 1 and 2.

scientific article published on 21 June 2013

Prospects of Next-Generation Vaccines for Bluetongue

scientific article published on 21 November 2019

Questionnaire survey about the motives of commercial livestock farmers and hobby holders to vaccinate their animals against Bluetongue virus serotype 8 in 2008-2009 in the Netherlands

scientific article published on 31 January 2010

RNA elements in open reading frames of the bluetongue virus genome are essential for virus replication

scientific article

Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep

scientific article published on 03 July 2013

Recombinant Newcastle disease viruses with targets for PCR diagnostics for rinderpest and peste des petits ruminants

scientific article published on 12 June 2018

Recovery of infectious classical swine fever virus (CSFV) from full-length genomic cDNA clones by a swine kidney cell line expressing bacteriophage T7 RNA polymerase.

scientific article published on March 1999

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.

scientific article published on 26 October 2016

Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV).

scientific article published on 2 July 2016

Rescue of recent virulent and avirulent field strains of bluetongue virus by reverse genetics

scientific article

Safety and protective efficacy of porcine reproductive and respiratory syndrome recombinant virus vaccines in young pigs.

scientific article published on June 2003

Sequence analysis of bluetongue virus serotype 8 from the Netherlands 2006 and comparison to other European strains.

scientific article published on August 2008

Significance of the oligosaccharides of the porcine reproductive and respiratory syndrome virus glycoproteins GP2a and GP5 for infectious virus production

scientific article published in December 2004

Structural Protein VP2 of African Horse Sickness Virus Is Not Essential for Virus Replication In Vitro.

scientific article

Sustained high-throughput polymerase chain reaction diagnostics during the European epidemic of Bluetongue virus serotype 8.

scientific article published on May 2012

The immune response of cattle, persistently infected with noncytopathic BVDV, after superinfection with antigenically semi-homologous cytopathic BVDV.

scientific article published on March 1998

The major envelope protein, GP5, of a European porcine reproductive and respiratory syndrome virus contains a neutralization epitope in its N-terminal ectodomain.

scientific article published on June 2003

Transplacental and oral transmission of wild-type bluetongue virus serotype 8 in cattle after experimental infection

scientific article published on 10 April 2009

Turnover Rate of NS3 Proteins Modulates Bluetongue Virus Replication Kinetics in a Host-Specific Manner

scientific article

VP2 Exchange and NS3/NS3a Deletion in African Horse Sickness Virus (AHSV) in Development of Disabled Infectious Single Animal Vaccine Candidates for AHSV.

scientific article published on 10 June 2015

VP2-serotyped live-attenuated bluetongue virus without NS3/NS3a expression provides serotype-specific protection and enables DIVA.

scientific article published on 31 October 2014

Vaccination of cattle against bovine viral diarrhoea

scientific article

Validation of a commercial ELISA for the detection of bluetongue virus (BTV)-specific antibodies in individual milk samples of Dutch dairy cows

scientific article published on 21 January 2008

Vector competence is strongly affected by a small deletion or point mutations in bluetongue virus

scientific article published on 11 October 2019

Vertical transmission of bluetongue virus serotype 8 virus in Dutch dairy herds in 2007.

scientific article published on 8 August 2009

Viral replication kinetics and in vitro cytopathogenicity of parental and reassortant strains of bluetongue virus serotype 1, 6 and 8.

scientific article published on 12 March 2014

Virus and host factors affecting the clinical outcome of bluetongue virus infection.

scientific article

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