List of works by Thomas Schmidt

A novel pretherapeutic gene expression-based risk score for treatment guidance in gastric cancer.

scientific article published on 23 October 2017

A phase 1 trial extension to assess immunologic efficacy and safety of prime-boost vaccination with VXM01, an oral T cell vaccine against VEGFR2, in patients with advanced pancreatic cancer.

scientific article published on 16 January 2018

ASO Author Reflections: Multimodal Treatment of Upper Gastrointestinal Signet Ring Cell Containing Cancer-Better Together

article

Angiogenesis: a target in solid tumors, also in leukemia?

scientific article published on January 2011

Angiogenic and growth factors in gastric cancer

scientific article published on 26 November 2014

Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial.

scientific article published on 16 March 2015

Bridges that guide and unite

scientific article published in Nature

Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice

scientific article published on 02 May 2022

Cavernous transformation of the portal vein in pancreatic cancer surgery-venous bypass graft first

scientific article published on 11 September 2020

Comparative Outcomes of Neoadjuvant Treatment Prior to Total Mesorectal Excision and Total Mesorectal Excision Alone in Selected Stage II/III Low and Mid Rectal Cancer.

scientific article published on 25 August 2015

Comparison of various surgical approaches for extensive bilateral colorectal liver metastases

scientific article published on 11 March 2014

Compartmental differences of circulating tumor cells in colorectal cancer

scientific article published on 10 January 2012

Current surgical treatment standards for esophageal and esophagogastric junction cancer

scientific article published on 14 August 2020

E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer

scientific article published on 22 February 2019

Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level

article

Expression analysis of aldehyde dehydrogenase 1A1 (ALDH1A1) in colon and rectal cancer in association with prognosis and response to chemotherapy

scientific article published on 10 August 2012

Expressional STAT3/STAT5 Ratio is an Independent Prognostic Marker in Colon Carcinoma

scientific article

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

article

Gastric Preconditioning in Advance of Esophageal Resection-Systematic Review and Meta-Analysis.

scientific article

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis ⬇️

scientific article

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

scientific article

High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases

scientific article published on 27 February 2019

Human mesenchymal stem cells enhance the systemic effects of radiotherapy.

scientific article

Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data

scientific article published on 31 December 2019

Impact of Tumor Localization and Molecular Subtypes on the Prognostic and Predictive Significance of p53 Expression in Gastric Cancer

scientific article published on 25 June 2020

Impact of anatomic location on locally recurrent rectal cancer: superior outcome for intraluminal tumour recurrence.

scientific article published on 31 March 2015

Inflammatory cytokines are associated with response and prognosis in patients with esophageal cancer

scientific article published on 7 May 2017

Influence of Different Neoadjuvant Chemotherapy Regimens on Response, Prognosis, and Complication Rate in Patients with Esophagogastric Adenocarcinoma.

scientific article published on 22 May 2015

Influence of age on resection of colorectal liver metastases.

scientific article published on 16 January 2015

Influence of two different resection techniques (conventional liver resection versus anterior approach) of liver metastases from colorectal cancer on hematogenous tumor cell dissemination - prospective randomized multicenter trial

scientific article

Infrahepatic inferior vena cava clamping for reduction of central venous pressure and blood loss during hepatic resection: a randomized controlled trial

scientific article published in June 2011

Loss Of Prolyl-Hydroxylase 1 Protects Against Biliary Fibrosis Via Attenuated Activation Of Hepatic Stellate Cells

scientific article published on 22 September 2018

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

scientific article published on June 2011

Machine learning for optimized individual survival prediction in resectable upper gastrointestinal cancer

scientific article published in 2022

Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.

scientific article

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.

scientific article published on 20 November 2009

Meta-analysis of standard, restrictive and supplemental fluid administration in colorectal surgery

scientific article published on April 2009

Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes

scientific article published on 25 March 2020

Neoadjuvant Therapy Improves Outcomes in Locally Advanced Signet-Ring-Cell Containing Esophagogastric Adenocarcinomas

scientific article published on 31 May 2018

Oligometastatic Gastroesophageal Adenocarcinoma: Molecular Pathophysiology and Current Therapeutic Approach

scientific article published on 31 January 2020

Pharmacological HIF-inhibition attenuates postoperative adhesion formation

scientific article published on 13 October 2017

Postoperative follow-up programs improve survival in curatively resected gastric and junctional cancer patients: a propensity score matched analysis.

scientific article

Prognostic differences in 8th edition TNM staging of esophagogastric adenocarcinoma after neoadjuvant treatment

scientific article published on 07 July 2018

Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein-Barr virus infection and high- and low-microsatellite instability

scientific article published on 17 June 2019

Prognostic indicators lose their value with repeated resection of colorectal liver metastases

scientific article published on 31 July 2018

Prognostic significance of microsatellite-instability in gastric and gastroesophageal junction cancer patients undergoing neoadjuvant chemotherapy

scientific article published on 04 January 2019

Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells

scientific article published on 26 February 2016

Prolyl Hydroxylase Inhibition Enhances Liver Regeneration Without Induction of Tumor Growth.

scientific article published in April 2017

Protein Profiling Gastric Cancer and Neighboring Control Tissues Using High-Content Antibody Microarrays.

scientific article

Regulation of angiogenesis by oxygen and metabolism.

scientific article published on February 2009

Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133(+) human colorectal cancer cells

scientific article

Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model

scientific article published on 14 February 2019

Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients

scientific article

Serum microRNA profiles as prognostic or predictive markers in the multimodality treatment of patients with gastric cancer

scientific article published on 9 June 2015

Serum microRNA profiles as prognostic/predictive markers in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction

scientific article published on 03 December 2014

Shared Genetic Etiology of Obesity-Related Traits and Barrett's Esophagus/Adenocarcinoma: Insights from Genome-Wide Association Studies

scientific article published on 20 November 2019

Short- and Long-Term Oncological Outcome After Rectal Cancer Surgery: a Systematic Review and Meta-Analysis Comparing Open Versus Laparoscopic Rectal Cancer Surgery

scientific article published on 27 March 2018

Significant decrease of mortality due to anastomotic leaks following esophageal resection: management makes the difference

scientific article published on 3 October 2017

Sphincter-Preserving Surgery for Low Rectal Cancer: Do We Overshoot the Mark?

scientific article

Splenectomy reduces lung metastases and tumoral and metastatic niche inflammation

scientific article published on 13 May 2019

Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma

scientific article

Surgery in oesophago-gastric cancer with metastatic disease: Treatment, prognosis and preoperative patient selection.

scientific article published on 29 May 2015

Surgical strategies in true adenocarcinoma of the esophagogastric junction (AEG II): thoracoabdominal or abdominal approach?

scientific article

TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.

scientific article published on 28 July 2016

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma

scientific article published on February 2013

The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk

scientific article published on 18 January 2016

The postoperative part of perioperative chemotherapy fails to provide a survival benefit in completely resected esophagogastric adenocarcinoma.

scientific article

Thoracoabdominal versus transhiatal surgical approaches for adenocarcinoma of the esophagogastric junction-a systematic review and meta-analysis

scientific article published on 03 January 2019

Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

scientific article published on 26 March 2015

Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases.

scientific article

VEGFR-1 expression levels predict occurrence of disseminated tumor cells in the bone marrow of patients with esophageal carcinoma

scientific article

VEGFR1+ Metastasis-Associated Macrophages Contribute to Metastatic Angiogenesis and Influence Colorectal Cancer Patient Outcome

scientific article published on 25 June 2019

Value of functional imaging by PET in esophageal cancer.

scientific article

YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis.

scientific article

[Gastric stump carcinoma: frequency, treatment, complications and prognosis].

scientific article published on 27 September 2016

[Importance of PET in surgery of esophageal cancer]

scientific article published on 01 June 2014

[Salvage surgery in esophageal cancer : Feasibility in patients after definitive radiochemotherapy (> 50 Gy)].

scientific article

[Surgical options in cancer of unknown primary (CUP)]

scientific article published on 01 February 2014

[Therapeutic approach in oligometastatic gastric and esophageal cancer]

scientific article published on 01 December 2017

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