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List of works by Thomas A Leonard

A molecular ruler regulates cytoskeletal remodelling by the Rho kinases

scientific article

A switch in nucleotide affinity governs activation of the Src and Tec family kinases.

scientific article published on 12 December 2017

A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation

scientific article published on 12 August 2019

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation

scientific article published on 06 April 2022

Coiled-coils: The long and short of it.

scientific article published on 5 August 2016

Conformational sampling of membranes by Akt controls its activation and inactivation

scientific article published on 9 April 2018

Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol ⬇️

scientific article published on January 1, 2013

Crystal Structure and Allosteric Activation of Protein Kinase C βII

scientific article

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. ⬇️

scientific article

Features critical for membrane binding revealed by DivIVA crystal structure

scientific article

In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate

scientific article published on 25 June 2021

It Takes Two to Tango: Activation of Protein Kinase D by Dimerization

scientific article published on 29 January 2020

Lipid-dependent Akt-ivity: where, when, and how

scientific article published on 30 May 2019

Made to measure - keeping Rho kinase at a distance.

scientific article published on 12 April 2016

Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11

scientific article published in 2023

Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations

scientific article published on 15 November 2018

Novel Features of DAG-Activated PKC Isozymes Reveal a Conserved 3-D Architecture.

scientific article

PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes

scientific article published in February 2017

Regulation of protein kinases by lipids

scientific article

Reply to Agarwal: Activity against nuclear substrates is not necessarily mediated by nuclear Akt

scientific article published on 15 June 2018

Structural analysis of the chromosome segregation protein Spo0J from Thermus thermophilus

scientific article published in July 2004

Structural determinants for phosphatidylinositol recognition by Sfh3 and substrate-induced dimer-monomer transition during lipid transfer cycles

scientific article

Towards understanding the molecular basis of bacterial DNA segregation.

scientific article

Two kinase family dramas

scientific article

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