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List of works by Willemijn Hobo

A phase I/II minor histocompatibility antigen-loaded dendritic cell vaccination trial to safely improve the efficacy of donor lymphocyte infusions in myeloma

scientific article published on 05 June 2017

AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8 T cells for adoptive immunotherapy

scientific article published on 06 August 2018

Addition of 10-Day Decitabine to Fludarabine/Total Body Irradiation Conditioning is Feasible and Induces Tumor-Associated Antigen-Specific T Cell Responses

article

Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 27 September 2012

B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation

scientific article published on 25 May 2012

CLEC12A-Mediated Antigen Uptake and Cross-Presentation by Human Dendritic Cell Subsets Efficiently Boost Tumor-Reactive T Cell Responses.

scientific article

Cell composition and expansion strategy can reduce the beneficial effect of AKT-inhibition on functionality of CD8+ T cells

scientific article published on 05 June 2020

Clinically applicable CD34<sup>+</sup>-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses

scientific article published on 01 April 2021

Coinhibitory molecules in hematologic malignancies: targets for therapeutic intervention

scientific article published on 04 May 2012

Comprehensive Phenotyping of T Cells Using Flow Cytometry

scientific article published on 04 February 2019

Decitabine enhances targeting of AML cells by CD34+ progenitor-derived NK cells in NOD/SCID/IL2Rgnull mice

scientific article

Efficient nontoxic delivery of PD-L1 and PD-L2 siRNA into dendritic cell vaccines using the cationic lipid SAINT-18.

scientific article published in May 2015

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo

scientific article published on 6 February 2017

IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells

scientific article published on 03 November 2020

Immune checkpoint molecules in acute myeloid leukaemia: managing the double-edged sword

scientific article published on 9 January 2018

Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients

scientific article published on 2 June 2013

Immunotherapeutic approaches to treat multiple myeloma

scientific article published on 11 December 2013

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation

scientific article published on 19 August 2012

Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation

scientific article published on 29 November 2017

Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy

scientific article

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application

scientific article published on 11 June 2015

Monocyte-Derived Dendritic Cells with Silenced PD-1 Ligands and Transpresenting Interleukin-15 Stimulate Strong Tumor-Reactive T-cell Expansion

scientific article published on 21 June 2017

Noninvasive Imaging of Tumor PD-L1 Expression Using Radiolabeled Anti-PD-L1 Antibodies

scientific article

PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer

article

PD-1/PD-L1 interactions contribute to functional T-cell impairment in patients who relapse with cancer after allogeneic stem cell transplantation

scientific article published on 9 June 2011

PD-L1 siRNA-mediated silencing in acute myeloid leukemia enhances anti-leukemic T cell reactivity

scientific article published on 11 June 2020

TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer

scientific article published on 08 November 2020

The impact of circulating suppressor cells in multiple myeloma patients on clinical outcome of DLIs.

scientific article published on 23 March 2015

Time to Akt: Superior tumor-reactive T cells for adoptive immunotherapy

scientific article published on 3 February 2015

siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice

scientific article published on 28 February 2015

siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells

scientific article published on 3 August 2010

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