List of works - Herta Steinkellner

A Dual-Approach Strategy to Optimize the Safety and Efficacy of Anti-Zika Virus Monoclonal Antibody Therapeutics

scientific article published in 2023

A PCR membrane spot assay for the detection of plum pox virus RNA in bark of infected trees

scientific article published in February 1991

A gene controlling sex in grapevines placed on a molecular marker-based genetic map

article

A genetic linkage map of Quercus robur L. (pedunculate oak) based on RAPD, SCAR, microsatellite, minisatellite, isozyme and 5S rDNA markers

article

A plant-derived human monoclonal antibody induces an anti-carbohydrate immune response in rabbits

scientific article published on 18 January 2008

A unique beta1,3-galactosyltransferase is indispensable for the biosynthesis of N-glycans containing Lewis a structures in Arabidopsis thaliana

scientific article

AllergoOncology: Expression platform development and functional profiling of an anti-HER2 IgE antibody

scientific article published on 27 May 2019

Amino-acid sequence comparison of nepovirus coat proteins

scientific article published in April 1992

Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.

scientific article published on June 2005

Arginine/lysine residues in the cytoplasmic tail promote ER export of plant glycosylation enzymes

scientific article published on November 2008

Characterization of plants expressing the human β1,4-galactosyltrasferase gene

scientific article published on 13 April 2015

Coat protein mediated resistance to Plum Pox Virus in Nicotiana clevelandii and N. benthamiana

scientific article published in February 1992

Construction of a functional CMP-sialic acid biosynthesis pathway in Arabidopsis

scientific article published on 7 March 2008

Controlled glycosylation of plant-produced recombinant proteins

scientific article

Detection of the trans activity of the plum pox virus NIa-like protease in infected plants

scientific article published in July 1990

Early screening for anti-plum pox virus monoclonal antibodies with different epitope specificities by means of gold-labelled immunosorbent electron microscopy

scientific article published in December 1988

Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3.

scientific article

Engineering of complex protein sialylation in plants

scientific article

Engineering of sialylated mucin-type O-glycosylation in plants

scientific article published on 4 September 2012

Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

scientific article

Enzymatic properties and subcellular localization of Arabidopsis beta-N-acetylhexosaminidases

scientific article published on 20 July 2007

Expression and glycoengineering of functionally active heteromultimeric IgM in plants

scientific article

Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis

article by Andreas Loos et al published April 2011 in Plant Physiology

Expression of functionally active sialylated human erythropoietin in plants

scientific article published on March 2013

Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue

scientific article

Fc-glycosylation influences Fcγ receptor binding and cell-mediated anti-HIV activity of monoclonal antibody 2G12.

scientific article published on November 2010

Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus

scientific article

Generation of Arabidopsis thaliana plants with complex N-glycans lacking beta1,2-linked xylose and core alpha1,3-linked fucose.

scientific article published in March 2004

Generation of biologically active multi-sialylated recombinant human EPOFc in plants

scientific article

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

scientific article

Glycan modulation and sulfoengineering of anti-HIV-1 monoclonal antibody PG9 in plants.

scientific article

Glyco-engineering in plants to produce human-like N-glycan structures

scientific article published on 14 August 2012

Glycosylation of plant produced human antibodies

scientific article

Identification of microsatellite sequences in Vitis riparia and their applicability for genotyping of different Vitis species

scientific article

Identification of mutagenic heterocyclic amines (IQ, Trp-P-1 and AalphaC) in the water of the Danube river

scientific article

IgG-Fc glycoengineering in non-mammalian expression hosts

scientific article published on 23 May 2012

Improved virus neutralization by plant-produced anti-HIV antibodies with a homogeneous beta1,4-galactosylated N-glycan profile

scientific article published on 28 May 2009

In Planta Glycan Engineering and Functional Activities of IgE Antibodies

scientific article published on 25 September 2019

In planta protein sialylation through overexpression of the respective mammalian pathway

scientific article published on 20 March 2010

In vitro and in vivo efficacy of anti-chikungunya virus monoclonal antibodies produced in wild-type and glycoengineered Nicotiana benthamiana plants

scientific article published on 26 June 2019

In vitro study on the effects of iron sucrose, ferric gluconate and iron dextran on redox-active iron and oxidative stress

scientific article published on January 2010

In vivo and in vitro activity of an immunoglobulin Fc fragment (Fcab) with engineered Her-2/neu binding sites.

scientific article published on 8 May 2014

Involvement of Intra-articular Corticotropin-releasing Hormone in Postoperative Pain Modulation

scientific article published on 01 February 2007

Microsatellite analysis of maternal half-sib families of Quercus robur , pedunculate oak: II. inferring the number of pollen donors from the offspring

Microsatellite analysis of maternal half-sib families of Quercus robur , pedunculate oak: detection of seed contaminations and inference of the seed parents from the offspring

Microsatellite variability in grapevine cultivars from different European regions and evaluation of assignment testing to assess the geographic origin of cultivars

article by K. M. Sefc et al published 16 February 2000 in Theoretical and Applied Genetics

Molecular cloning and characterization of Arabidopsis thaliana Golgi alpha-mannosidase II, a key enzyme in the formation of complex N-glycans in plants

scientific article published on March 2006

Molecular cloning and characterization of cDNA coding for beta1, 2N-acetylglucosaminyltransferase I (GlcNAc-TI) from Nicotiana tabacum.

scientific article

Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana.

scientific article

Molecular cloning and heterologous expression of beta1,2-xylosyltransferase and core alpha1,3-fucosyltransferase from maize

scientific article published on 22 August 2006

Molecular cloning of cDNA encoding N-acetylglucosaminyltransferase II from Arabidopsis thaliana

scientific article published in December 1999

Monoclonal antibody therapy for Junin virus infection

scientific article published on 4 April 2016

Mutational analysis of the virion-sense genes of maize streak virus

scientific article published on September 1989

N-Glyco-Engineering in Plants: Update on Strategies and Major Achievements

scientific article published on January 2015

N-glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans

scientific article published on 11 February 2011

N-glycosylation of plant-produced recombinant proteins

scientific article published on January 2013

Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana

scientific article

Partial sequence identification of grapevine-leafroll-associated virus-1 and development of a highly sensitive IC-RT-PCR detection method

scientific article published in April 2000

Plant glyco-biotechnology on the way to synthetic biology

scientific article

Plant-Based Vaccines & Antibodies 2007 - Second International Conference

article

Plant-based heterologous expression of Mal d 2, a thaumatin-like protein and allergen of apple (Malus domestica), and its characterization as an antifungal protein

scientific article

Plant-produced anti-dengue virus monoclonal antibodies exhibit reduced antibody-dependent enhancement of infection activity.

scientific article

Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation

scientific article

Production of a monoclonal antibody in plants with a humanized N-glycosylation pattern

scientific article published in September 2007

Production of a tumour-targeting antibody with a human-compatible glycosylation profile in N. benthamiana hairy root cultures

scientific article published on 17 June 2016

Production of monoclonal antibodies with a controlled N-glycosylation pattern in seeds of Arabidopsis thaliana

article

Promoter Choice Impacts the Efficiency of Plant Glyco-Engineering.

scientific article published on 29 July 2017

Proteolytic and N-glycan processing of human α1-antitrypsin expressed in Nicotiana benthamiana

scientific article published in 2014

Rapid Production of Recombinant Allergens in Nicotiana benthamiana and Their Impact on Diagnosis and Therapy

article

Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody

scientific article (publication date: 2011)

Recombinant plant-derived human IgE glycoproteomics

scientific article published on 8 April 2017

Reconstruction of a grapevine pedigree by microsatellite analysis

article

Reduced paucimannosidic N-glycan formation by suppression of a specific β-hexosaminidase from Nicotiana benthamiana

scientific article

Regeneration of transgenic plants of Prunus armeniaca containing the coat protein gene of Plum Pox Virus

scientific article published in February 1992

Secretion of biologically active glycoforms of bovine follicle stimulating hormone in plants

scientific article

Self-hybridization of hybridomas leads to stabilization of clones and increased yield of monoclonal antibodies

scientific article published on 01 January 1987

Sequential depletion and acquisition of proteins during Golgi stack disassembly and reformation

scientific article published on 18 August 2010

Significant impact of single N-glycan residues on the biological activity of Fc-based antibody-like fragments

scientific article

Steric Accessibility of the Cleavage Sites Dictates the Proteolytic Vulnerability of the Anti-HIV-1 Antibodies 2F5, 2G12, and PG9 in Plants

scientific article published on 08 November 2019

Stopping the DNA polymerase activity at a specific site with a dideoxyoligonucleotide: selective labelling of single stranded circular DNA

scientific article published on October 1989

The Golgi localization of Arabidopsis thaliana beta1,2-xylosyltransferase in plant cells is dependent on its cytoplasmic and transmembrane sequences

scientific article published on 01 September 2002

The high efficiency, human B cell immortalizing heteromyeloma CB-F7. Production of human monoclonal antibodies to human immunodeficiency virus

scientific article published on February 1988

The human anti-HIV antibodies 2F5, 2G12, and PG9 differ in their susceptibility to proteolytic degradation: down-regulation of endogenous serine and cysteine proteinase activities could improve antibody production in plant-based expression platforms

scientific article published on April 2014

The use of microsatellites for germplasm management in a Portuguese grapevine collection

article

Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody.

scientific article published on April 2017

Transient Expression of Mammalian Genes in N. benthamiana to Modulate N-Glycosylation

scientific article published in January 2016

Transient Glyco-Engineering to Produce Recombinant IgA1 with Defined N- and O-Glycans in Plants

scientific article published on 29 January 2016

Unaltered complex N-glycan profiles in Nicotiana benthamiana despite drastic reduction of beta1,2- N -acetylglucosaminyltransferase I activity

scientific article published in January 2004

Vacuolar targeting of recombinant antibodies in Nicotiana benthamiana

scientific article published on 9 May 2016

Within-population genetic structure in Quercus robur L. and Quercus petraea (Matt.) Liebl. assessed with isozymes and microsatellites

scientific article published in 1998

List of works by Herta Steinkellner

A Dual-Approach Strategy to Optimize the Safety and Efficacy of Anti-Zika Virus Monoclonal Antibody Therapeutics

A PCR membrane spot assay for the detection of plum pox virus RNA in bark of infected trees

A gene controlling sex in grapevines placed on a molecular marker-based genetic map

A genetic linkage map of Quercus robur L. (pedunculate oak) based on RAPD, SCAR, microsatellite, minisatellite, isozyme and 5S rDNA markers

A plant-derived human monoclonal antibody induces an anti-carbohydrate immune response in rabbits

A unique beta1,3-galactosyltransferase is indispensable for the biosynthesis of N-glycans containing Lewis a structures in Arabidopsis thaliana

AllergoOncology: Expression platform development and functional profiling of an anti-HER2 IgE antibody

Amino-acid sequence comparison of nepovirus coat proteins

Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.

Arginine/lysine residues in the cytoplasmic tail promote ER export of plant glycosylation enzymes

Characterization of plants expressing the human β1,4-galactosyltrasferase gene

Coat protein mediated resistance to Plum Pox Virus in Nicotiana clevelandii and N. benthamiana

Construction of a functional CMP-sialic acid biosynthesis pathway in Arabidopsis

Controlled glycosylation of plant-produced recombinant proteins

Detection of the trans activity of the plum pox virus NIa-like protease in infected plants

Early screening for anti-plum pox virus monoclonal antibodies with different epitope specificities by means of gold-labelled immunosorbent electron microscopy

Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3.

Engineering of complex protein sialylation in plants

Engineering of sialylated mucin-type O-glycosylation in plants

Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

Enzymatic properties and subcellular localization of Arabidopsis beta-N-acetylhexosaminidases

Expression and glycoengineering of functionally active heteromultimeric IgM in plants

Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis

Expression of functionally active sialylated human erythropoietin in plants

Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue

Fc-glycosylation influences Fcγ receptor binding and cell-mediated anti-HIV activity of monoclonal antibody 2G12.

Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus

Generation of Arabidopsis thaliana plants with complex N-glycans lacking beta1,2-linked xylose and core alpha1,3-linked fucose.

Generation of biologically active multi-sialylated recombinant human EPOFc in plants

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

Glycan modulation and sulfoengineering of anti-HIV-1 monoclonal antibody PG9 in plants.

Glyco-engineering in plants to produce human-like N-glycan structures

Glycosylation of plant produced human antibodies

Identification of microsatellite sequences in Vitis riparia and their applicability for genotyping of different Vitis species

Identification of mutagenic heterocyclic amines (IQ, Trp-P-1 and AalphaC) in the water of the Danube river

IgG-Fc glycoengineering in non-mammalian expression hosts

Improved virus neutralization by plant-produced anti-HIV antibodies with a homogeneous beta1,4-galactosylated N-glycan profile

In Planta Glycan Engineering and Functional Activities of IgE Antibodies

In planta protein sialylation through overexpression of the respective mammalian pathway

In vitro and in vivo efficacy of anti-chikungunya virus monoclonal antibodies produced in wild-type and glycoengineered Nicotiana benthamiana plants

In vitro study on the effects of iron sucrose, ferric gluconate and iron dextran on redox-active iron and oxidative stress

In vivo and in vitro activity of an immunoglobulin Fc fragment (Fcab) with engineered Her-2/neu binding sites.

Involvement of Intra-articular Corticotropin-releasing Hormone in Postoperative Pain Modulation

Microsatellite analysis of maternal half-sib families of Quercus robur , pedunculate oak: II. inferring the number of pollen donors from the offspring

Microsatellite analysis of maternal half-sib families of Quercus robur , pedunculate oak: detection of seed contaminations and inference of the seed parents from the offspring

Microsatellite variability in grapevine cultivars from different European regions and evaluation of assignment testing to assess the geographic origin of cultivars

Molecular cloning and characterization of Arabidopsis thaliana Golgi alpha-mannosidase II, a key enzyme in the formation of complex N-glycans in plants

Molecular cloning and characterization of cDNA coding for beta1, 2N-acetylglucosaminyltransferase I (GlcNAc-TI) from Nicotiana tabacum.

Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana.

Molecular cloning and heterologous expression of beta1,2-xylosyltransferase and core alpha1,3-fucosyltransferase from maize

Molecular cloning of cDNA encoding N-acetylglucosaminyltransferase II from Arabidopsis thaliana

Monoclonal antibody therapy for Junin virus infection

Mutational analysis of the virion-sense genes of maize streak virus

N-Glyco-Engineering in Plants: Update on Strategies and Major Achievements

N-glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans

N-glycosylation of plant-produced recombinant proteins

Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana

Partial sequence identification of grapevine-leafroll-associated virus-1 and development of a highly sensitive IC-RT-PCR detection method

Plant glyco-biotechnology on the way to synthetic biology

Plant-Based Vaccines & Antibodies 2007 - Second International Conference

Plant-based heterologous expression of Mal d 2, a thaumatin-like protein and allergen of apple (Malus domestica), and its characterization as an antifungal protein

Plant-produced anti-dengue virus monoclonal antibodies exhibit reduced antibody-dependent enhancement of infection activity.

Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation

Production of a monoclonal antibody in plants with a humanized N-glycosylation pattern

Production of a tumour-targeting antibody with a human-compatible glycosylation profile in N. benthamiana hairy root cultures

Production of monoclonal antibodies with a controlled N-glycosylation pattern in seeds of Arabidopsis thaliana

Promoter Choice Impacts the Efficiency of Plant Glyco-Engineering.

Proteolytic and N-glycan processing of human α1-antitrypsin expressed in Nicotiana benthamiana

Rapid Production of Recombinant Allergens in Nicotiana benthamiana and Their Impact on Diagnosis and Therapy

Rapid high yield production of different glycoforms of Ebola virus monoclonal antibody

Recombinant plant-derived human IgE glycoproteomics

Reconstruction of a grapevine pedigree by microsatellite analysis

Reduced paucimannosidic N-glycan formation by suppression of a specific β-hexosaminidase from Nicotiana benthamiana

Regeneration of transgenic plants of Prunus armeniaca containing the coat protein gene of Plum Pox Virus

Secretion of biologically active glycoforms of bovine follicle stimulating hormone in plants

Self-hybridization of hybridomas leads to stabilization of clones and increased yield of monoclonal antibodies

Sequential depletion and acquisition of proteins during Golgi stack disassembly and reformation

Significant impact of single N-glycan residues on the biological activity of Fc-based antibody-like fragments

Steric Accessibility of the Cleavage Sites Dictates the Proteolytic Vulnerability of the Anti-HIV-1 Antibodies 2F5, 2G12, and PG9 in Plants