List of works - Dave Boucher

Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD

scientific article published on 28 April 2020

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

scientific article published on 6 February 2018

Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis.

scientific article published on 26 March 2012

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

scientific article published on 16 April 2018

Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome

scientific article published on 06 December 2018

Divide to conquer: NLRP3 is activated on dispersed trans-Golgi network

scientific article published on 01 March 2019

General in vitro caspase assay procedures

scientific article published on 01 January 2014

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria

scientific article published on 24 June 2020

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

scientific article published on 01 August 2018

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

scientific article published on 13 May 2019

Molecular determinants involved in activation of caspase 7

scientific article published on August 2011

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

scientific article published on 14 July 2015

Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

scientific article published on 01 August 2018

Quantifying Caspase-1 Activity in Murine Macrophages

scientific article published in January 2018

Salmonella-induced inflammasome activation in humans

scientific article published on 11 December 2016

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses

article

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

scientific article published on 14 March 2019

List of works by Dave Boucher