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List of works by Simon G. Patching

2-Aminotetralones: novel inhibitors of MurA and MurZ.

scientific article published on 30 January 2008

A systematic approach to the amplified expression, functional characterization and purification of inositol transporters from Bacillus subtilis

scientific article published on 18 October 2012

Allantoin transport protein, PucI, from Bacillus subtilis: evolutionary relationships, amplified expression, activity and specificity ⬇️

scientific article

Amino acid composition analysis of human secondary transport proteins and implications for reliable membrane topology prediction

scientific article published on 9 May 2016

Amino acid composition analysis of secondary transport proteins from Escherichia coli with relation to functional classification, ligand specificity and structure

scientific article published on 14 January 2015

Bacterial Multidrug Efflux Proteins: A Major Mechanism of Antimicrobial Resistance

scientific article

Benzothioxalone derivatives as novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferases (MurA and MurZ).

scientific article

Characterisation of the DAACS Family Escherichia coli Glutamate/Aspartate-Proton Symporter GltP Using Computational, Chemical, Biochemical and Biophysical Methods

scientific article published on 26 December 2016

Comprehensive analysis of the numbers, lengths and amino acid compositions of transmembrane helices in prokaryotic, eukaryotic and viral integral membrane proteins of high-resolution structure

scientific article

Deuterated detergents for structural and functional studies of membrane proteins: Properties, chemical synthesis and applications

scientific article published on 24 February 2016

Efficient syntheses of 13C- and 14C-labelled 5-benzyl and 5-indolylmethyl L-hydantoins

Efflux proteins at the blood-brain barrier: review and bioinformatics analysis

scientific article published on 8 May 2017

Equipping a Research Scale Fermentation Laboratory for Production of Membrane Proteins

article

Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery

scientific article

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin ⬇️

scientific article published on 11 April 2017

Interactions of the intact FsrC membrane histidine kinase with its pheromone ligand GBAP revealed through synchrotron radiation circular dichroism.

scientific article published in July 2012

Interactions of the intact FsrC membrane histidine kinase with the tricyclic peptide inhibitor siamycin I revealed through synchrotron radiation circular dichroism

scientific article published on 26 November 2012

Ligand orientation in a membrane-embedded receptor site revealed by solid-state NMR with paramagnetic relaxation enhancement

Ligand- and drug-binding studies of membrane proteins revealed through circular dichroism spectroscopy

scientific article

Low 13C-background for NMR-based studies of ligand binding using 13C-depleted glucose as carbon source for microbial growth: 13C-labeled glucose and 13C-forskolin binding to the galactose-H+ symport protein GalP in Escherichia coli

scientific article

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 ⬇️

scientific article

Multiplex polymerase chain reaction detection of Shiga toxin genes and antibiotic sensitivity of Escherichia coli O157:H7 isolated from beef meat in Quetta, Pakistan

article

NMR structures of polytopic integral membrane proteins ⬇️

scientific article published on August 2, 2011

NMR-Active Nuclei for Biological and Biomedical Applications

Nucleoside transporters in PET imaging of proliferating cancer cells using 3ꞌ-deoxy-3ꞌ-[18F]fluoro-L-thymidine

Overcoming challenges for amplified expression of recombinant proteins using Escherichia coli

scientific article published on 24 November 2017

Probing metal ion substrate-binding to the E. coli ZitB exporter in native membranes by solid state NMR.

scientific article published in December 2008

Probing the contacts of a low-affinity substrate with a membrane-embedded transport protein using 1H-13C cross-polarisation magic-angle spinning solid-state NMR.

scientific article published on 23 November 2012

Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family

scientific article published on September 2004

Purification of bacterial membrane sensor kinases and biophysical methods for determination of their ligand and inhibitor interactions ⬇️

scientific article

Recent developments in nucleobase cation symporter-1 (NCS1) family transport proteins from bacteria, archaea, fungi and plants

article

Relative substrate affinities of wild-type and mutant forms of the Escherichia coli sugar transporter GalP determined by solid-state NMR.

scientific article

Retraction of "Characterization of the Escherichia coli Concentrative Nucleoside Transporter NupC Using Computational, Biochemical, and Biophysical Methods".

scientific article

Roles of facilitative glucose transporter GLUT1 in [18F]FDG positron emission tomography (PET) imaging of human diseases

Solid-State NMR Spectroscopy in Drug Design and Discovery

scholarly article published 2 October 2013

Solid-state NMR spectroscopy detects interactions between tryptophan residues of the E. coli sugar transporter GalP and the alpha-anomer of the D-glucose substrate

scientific article published on 5 January 2008

Solid-state NMR structures of integral membrane proteins

scientific article published on 8 February 2016

Structural analysis of uniformly (13)C-labelled solids from selective angle measurements at rotational resonance.

scientific article published on 9 May 2009

Structural genomics of bacterial membrane transport proteins

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

scientific article

Surface plasmon resonance spectroscopy for characterisation of membrane protein-ligand interactions and its potential for drug discovery

scientific article published on 09 May 2013

Synthesis of highly pure14C-labelledDL-allantoin and13C NMR analysis of labelling integrity

Synthesis of uniformly deuterated n-dodecyl-β-D-maltoside (d39-DDM) for solubilization of membrane proteins in TROSY NMR experiments

scientific article published on 9 December 2014

Synthesis, NMR analysis and applications of isotope-labelled hydantoins

TROSY NMR with a 52 kDa sugar transport protein and the binding of a small-molecule inhibitor.

scientific article

The Nucleobase-Cation-Symport-1 Family of Membrane Transport Proteins

The economical synthesis of [2'-(13)C, 1,3-(15)N2]uridine; preliminary conformational studies by solid state NMR.

scientific article published in June 2003

The nucleoside transport proteins, NupC and NupG, from Escherichia coli: specific structural motifs necessary for the binding of ligands

scientific article

Transcriptomic and biochemical analyses identify a family of chlorhexidine efflux proteins

scientific article

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