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List of works by Francisco Lozano

A case of aggressive bullous pemphigoid associated with the defective functional variant of Fc gamma receptor IIb: implications for pathogenesis?

scientific article published on 01 November 2011

A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase.

scientific article published on 08 July 2011

A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting

scientific article (publication date: 22 March 2002)

A reporter gene to analyse the hypermutation of immunoglobulin genes.

scientific article

A role for human Sp alpha as a pattern recognition receptor

scientific article

Affinity maturation leads to differential expression of multiple copies of a κ light-chain transgene

scientific article published in Nature

Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients

scientific article

Association between mannose-binding lectin deficiency and septic shock following acute pyelonephritis due to Escherichia coli

scientific article published on 3 January 2007

Association of an activation inducible serine kinase activity with CD5.

scientific article published on November 1993

Association of mannose-binding lectin gene polymorphisms with antiphospholipid syndrome, cardiovascular disease and chronic damage in patients with systemic lupus erythematosus

article

Association of syntenin-1 with M-RIP polarizes Rac-1 activation during chemotaxis and immune interactions

scientific article

Autoantibodies against nuclear envelope-associated proteins in primary biliary cirrhosis

scientific article published on 01 July 1988

Basophils, IgE, and autoantibody-mediated kidney disease

scientific article published on June 2011

Biochemical and serological characterization of a public antigenic determinant present on HLA-B molecules.

scientific article published on April 1990

Biochemical characterization of recombinant and circulating human Spalpha.

scientific article published in April 2004

CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts ⬇️

scientific article published on June 15, 1998

CD43 monoclonal antibodies recognize the large sialoglycoprotein of human leukocytes

scientific article published on 01 October 1987

CD5 as a Target for Immune-Based Therapies

scientific article published on January 2015

CD6 modulates thymocyte selection and peripheral T cell homeostasis

scientific article published on 04 July 2016

Characterization of a new HLA-C allele: Cw*1606

scientific article published on 01 October 2003

Clinical and experimental evidence for targeting CD6 in immune-based disorders.

scientific article published on 8 March 2018

Cloning of S4D-SRCRB, a new soluble member of the group B scavenger receptor cysteine-rich family (SRCR-SF) mapping to human chromosome 7q11.23.

scientific article

Commentary: CD6 As a Potential Target for Treating Multiple Sclerosis.

scientific article published on 29 September 2017

Commentary: The Scavenger Receptor SSc5D Physically Interacts with Bacteria through the SRCR-Containing N-Terminal Domain

scientific article published on 28 March 2017

Conformation of the hypervariable region L3 without the key proline residue.

scientific article

Conservation of a polymorphic microsatellite at orthologous positions in the human and mouse CD5 gene promoter

scientific article published on 01 January 1997

Conserved Bacterial-Binding Peptides of the Scavenger-Like Human Lymphocyte Receptor CD6 Protect From Mouse Experimental Sepsis.

scientific article

Corrigendum to "Genetically defined variants of toll-like receptors 3, 7 and 9 as phenotype and risk modifier factors for psoriasis" [89 (March (3)) (2018) 301-304].

scientific article

Corrigendum: Commentary: The Scavenger Receptor SSc5D Physically Interacts with Bacteria through the SRCR-Containing N-Terminal Domain

scientific article published on 29 November 2017

Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain

scientific article

Cytokines as therapeutic targets in primary Sjögren syndrome

scientific article

Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen-induced T-cell activation

scientific article published on 01 January 1997

Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes

scientific article published in April 1993

Differential effects of anti-CD45 monoclonal antibody on human B cell proliferation: a monoclonal antibody recognizing a neuraminidase-sensitive epitope of the T200 molecule enhances anti-immunoglobulin-induced proliferation

scientific article published on 01 December 1990

Discordant susceptibility of inbred C57BL/6 versus outbred CD1 mice to experimental fungal sepsis

scientific article published on 09 January 2019

Discrepancies between serology- and sequence-based typing of HLA class I alleles among unrelated donor/recipient pairs

scientific article published on 01 September 1999

Donor mannose-binding lectin gene polymorphisms influence the outcome of liver transplantation

scientific article published on 01 October 2009

Effect of protein kinase C activators on the phosphorylation and the surface expression of the CDw50 leukocyte antigen

scientific article published on 01 January 1992

Erratum for Martínez-Florensa et al., "Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis".

scientific article published on 24 October 2017

Etiopathogenic role of surfactant protein d in the clinical and immunological expression of primary Sjögren syndrome

scientific article published on 01 November 2014

Evolutionarily conserved transcription regulatory elements within the 5'-flanking region of the human CD5 gene.

scientific article published in March 1996

Evolutionary and functional evidence for positive selection at the human CD5 immune receptor gene

scientific article published on 13 October 2011

Existence of a soluble form of CD50 (intercellular adhesion molecule-3) produced upon human lymphocyte activation. Present in normal human serum and levels are increased in the serum of systemic lupus erythematosus patients

scientific article published on 01 March 1995

Exploiting scavenger receptors in cancer immunotherapy: Lessons from CD5 and SR-B1.

scientific article

Expression of interleukin-8 receptors (CXCR1 and CXCR2) in premenopausal women with recurrent urinary tract infections.

scientific article

Expression of the innate defense receptor S5D-SRCRB in the urogenital tract

scientific article

Expression, purification and crystallization of human CD5 domain III, a nano-scale crystallization example.

scientific article

FCGR2A/CD32A and FCGR3A/CD16A variants and EULAR response to tumor necrosis factor-α blockers in psoriatic arthritis: a longitudinal study with 6 months of followup

scientific article published in April 2012

Functional relevance of a non-synonymous substitution in the CD5 gene (V471A) targeted for positive selection in East Asian populations

scientific article published on 25 November 2010

Functional requirement of tyrosine residue 429 within CD5 cytoplasmic domain for regulation of T cell activation and survival

scientific article

Genetic and experimental evidence for the involvement of the CD6 lymphocyte receptor in psoriasis.

scientific article published on 11 December 2017

Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children

scientific article

Genetic variants of innate immune receptors and infections after liver transplantation.

scientific article

Genetically defined variants of toll-like receptors 3, 7 and 9 as phenotype and risk modifier factors for psoriasis

scientific article published on 19 December 2017

Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke

scientific article

Genomic instability at the human CD5 gene promoter

scientific article published on 01 March 2002

Genomic organization of the human CD5 gene

scientific article published in October 2000

Genotypes coding for low serum levels of mannose-binding lectin are underrepresented among individuals suffering from noninfectious systemic inflammatory response syndrome

scientific article

Gut microbiota metabolites for sweetening type I diabetes.

scientific article

HLA-B*5130, a new HLA-B allele carrying a rare nucleotide substitution in exon 4

scientific article published on 01 January 2003

Heterogeneity in the electrophoretic mobility of CD5 molecules after phorbol ester stimulation

scientific article published on 01 December 1989

High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome

scientific article published on 01 September 2001

High prevalence of genetically-determined mannose binding lectin deficiency in young children with invasive pneumococcal disease

scientific article published on 25 March 2014

Human CD6 Down-Modulation following T-Cell Activation Compromises Lymphocyte Survival and Proliferative Responses

scientific article

Identification and functional characterization of the hepatic stellate cell CD38 cell surface molecule

scientific journal article

Identification of a natural soluble form of human CD5

scientific article published on 01 August 1999

Identification of a new HLA-DRB1 allele (DRB1*0318) in three members of a Caucasian Spanish family

scientific article

Identification of a novel HLA-Cw*07 variant (Cw*0714) in a German Caucasian family

scientific article published in January 2000

Identification of a novel single-nucleotide polymorphism (Val554Ile) and definition of eight common alleles for human IL4RA exon 11.

scientific article published in March 2001

Identification of functionally relevant phoshorylatable serine clusters in the cytoplasmic region of the human CD6 lymphocyte surface receptor.

scientific article published on 24 May 2013

Identification of the amino acid residues defining an intralocus determinant in the alpha 1 domain of HLA-A molecules

scientific article published on 01 January 1989

Immune Reconstitution in Severely Immunosuppressed Antiretroviral-Naive HIV-1-Infected Patients Starting Efavirenz, Lopinavir-Ritonavir, or Atazanavir-Ritonavir Plus Tenofovir/Emtricitabine: Final 48-Week Results (The Advanz-3 Trial).

scientific article published on June 2015

Immune and stress mediators in response to bilateral adnexectomy: comparison of single-port access and conventional laparoscopy in a porcine model

scientific article published on 27 March 2014

Immunomodulatory effects of soluble CD5 on experimental tumor models.

scientific article published on 20 November 2017

Impact of the functional CD5 polymorphism A471V on the response of chronic lymphocytic leukaemia to conventional chemotherapy regimens

scientific article published on 15 March 2016

Impaired post-transcriptional expression of interleukin-2 receptor in pokeweed mitogen-activated T cells.

scientific article published in April 1992

Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling

scientific article published on August 2009

Induction of interleukin 2 (IL 2) and interferon-gamma and enhancement of IL 2 receptor expression by a CD26 monoclonal antibody

scientific article published on 01 April 1991

Influence of Mannose-Binding Lectin Gene Polymorphisms on The Invasiveness of Cytomegalovirus Disease After Solid Organ Transplantation

article

Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis.

scientific article published on 17 October 2008

Influence of variants of Fcg receptor IIA on the European league against rheumatism responses to anti-tumour necrosis factor alpha therapy in psoriatic arthritis.

scientific article

Inherited functional variants of the lymphocyte receptor CD5 influence melanoma survival

scientific article

Interaction of recombinant and natural soluble CD5 forms with an alternative cell surface ligand

scientific article published on July 1999

Interleukin-4 receptor alpha polymorphisms in primary Sjögren's syndrome.

scientific article

Intracellular events involved in CD5-induced human T cell activation and proliferation

scientific article published on 01 March 1992

Intravenous immune globulin effects on serum-soluble CD5 levels in atopic dermatitis

scientific article published on 01 December 2001

Involvement of the CDw50 molecule in allorecognition

scientific article published on November 1990

Is mannose-binding lectin deficiency associated with infection due to Gram-positive bacteria?

scientific article published in December 2008

Isolation and characterisation of a CDw50 negative Jurkat T-cell line variant (PPL.1).

scientific article published on January 1993

Isolation of two CD50 (ICAM-3)-negative Jurkat T-cell clones and their application for analysis of CD50 function.

scientific article published in May 1998

Liver X receptors inhibit macrophage proliferation through downregulation of cyclins D1 and B1 and cyclin-dependent kinases 2 and 4.

scientific article published on 11 March 2011

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

scientific article published on October 1994

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

scientific article published on 01 October 2020

Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation

scientific article published on 01 October 2006

Mannose-Binding Lectin-Deficient Donors Increase the Risk of Bacterial Infection and Bacterial Infection-Related Mortality After Liver Transplantation.

scientific article published on 26 June 2017

Mannose-binding lectin-deficient genotypes as a risk factor of pneumococcal meningitis in infants

scientific article

Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjogren's syndrome

article

Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface receptor.

scientific article

Modulation of CD6 function through interaction with Galectin-1 and -3

scientific article

Molecular and functional characterization of mouse S5D-SRCRB: a new group B member of the scavenger receptor cysteine-rich superfamily

scientific journal article

Multifaceted effects of soluble human CD6 in experimental cancer models

scientific article published on 01 March 2020

Novel MASP2 variants detected among North African and Sub-Saharan individuals.

scientific article published on August 2005

Oral Administration of Pentoxifylline Reduces Endometriosis-Like Lesions in a Nude Mouse Model.

scientific article published on 12 October 2016

Ovarian endometrioma but not deep infiltrating endometriosis is associated with increased serum levels of interleukin-8 and interleukin-6

scientific article published on 20 July 2012

Pattern Recognition by CD6: A Scavenger-Like Lymphocyte Receptor

scientific article published on 16 March 2015

Pattern of soluble CD5 and CD6 lymphocyte receptors in critically ill patients with septic syndromes.

scientific article published on 9 May 2015

Persistent low C3 levels associated with meningococcal meningitis and membranoproliferative glomerulonephritis

scientific article published on 01 January 1990

Phosphorylation-mediated changes in the electrophoretic mobility of CD5 molecules

scientific article published on 01 October 1990

Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells

scientific article published on 01 April 2000

Polymorphic receptors of the innate immune system (MBL/MASP-2 and TLR2/4) and susceptibility to pneumococcal bacteremia in HIV-infected patients: a case-control study

scientific article published in March 2009

Polymorphisms in the interleukin-4 receptor alpha chain gene influence susceptibility to HIV-1 infection and its progression to AIDS.

scientific article

Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis.

scientific article published on 28 November 2016

Protein kinase C-dependent up-regulation of CD5 surface expression on normal and lymphoblastoid T cells

scientific article published on August 1990

Relevance of CD6-mediated interactions in T cell activation and proliferation

scientific article

Role of CD5/CD5L interactions in the homeostasis of regulatory lymphocyte subpopulations and the control of autoimmune disorders

scientific article published on 23 November 2011

Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling

scientific article (publication date: 2001)

Signaling through CD5 involves acidic sphingomyelinase, protein kinase C-zeta, mitogen-activated protein kinase kinase, and c-Jun NH2-terminal kinase

scientific article published on 01 May 1999

Soluble CD5 and CD6: Lymphocytic Class I Scavenger Receptors as Immunotherapeutic Agents

scientific article published on 03 December 2020

Stimulation through the TCR/CD3 complex up-regulates the CD2 surface expression on human T lymphocytes

scientific article published on 01 February 1991

Subacute cutaneous lupus erythematosus: clinicopathologic findings in thirteen cases

scientific article published in December 1988

Targeting of key pathogenic factors from gram-positive bacteria by the soluble ectodomain of the scavenger-like lymphocyte receptor CD6.

scientific article published on 21 November 2013

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

scientific article

The CD5 ectodomain interacts with conserved fungal cell wall components and protects from zymosan-induced septic shock-like syndrome

scholarly article

The Influence of Innate Immunity Gene Receptors Polymorphisms in Renal Transplant Infections

article

The Protein Kinase C-Independent Human B Cell Proliferation Induced via Surface Immunoglobulins is Unaffected by CD45 Monoclonal Antibodies ⬇️

scientific article published on March 1, 1991

The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells

scientific article

The carboxy-terminal region of CD5 is required for c-CBL mediated TCR signaling downmodulation in thymocytes

scientific article published on 30 January 2013

The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis

scientific article

The cytoplasmic domain of CD5 mediates both TCR/CD3-dependent and -independent diacylglycerol production

scientific article published on 01 November 1997

The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis

scientific article published on 30 November 2018

The human CD6 gene is transcriptionally regulated by RUNX and Ets transcription factors in T cells.

scientific article

The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease.

scientific article published on 07 April 2011

The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains

scientific article

The lymphocyte scavenger receptor CD5 plays a nonredundant role in fungal infection

scientific article published on 24 April 2020

The lymphocytic scavenger receptor CD5 shows therapeutic potential in mouse models of fungal infection

scientific article published on 12 October 2020

The macrophage soluble receptor AIM/Api6/CD5L displays a broad pathogen recognition spectrum and is involved in early response to microbial aggression

scientific article published on 3 March 2014

The role of Fc gamma receptors polymorphisms in bullous pemphigoid

scientific article published on 01 July 2010

The role of Fcγ receptor polymorphisms in the response to anti–tumor necrosis factor therapy in psoriasis A pharmacogenetic study

scientific article published on 01 September 2013

Therapeutic targeting of B cells for rheumatic autoimmune diseases

scientific article published on 18 January 2011

Thrombotic microangiopathic haemolytic anaemia and antiphospholipid antibodies

scientific article

Toll-like receptor 9 promoter polymorphism as a predictive factor of narrow-band UVB phototherapy response in patients with psoriasis

article

Transcriptional regulation of human CD5: important role of Ets transcription factors in CD5 expression in T cells.

scientific article published on June 2004

Transgenic expression of soluble human CD5 enhances experimentally-induced autoimmune and anti-tumoral immune responses

scientific article published on 15 January 2014

Transient immunologic defect in a case of Listeria rhombencephalitis

scientific article published on 01 June 1987

Treatment of Experimental Autoimmune Encephalomyelitis by Sustained Delivery of Low-Dose IFN-α

scientific article published on 17 June 2019

[Anti-nuclear envelope antibodies associated with Sjogren's syndrome and non-Hodgkin's lymphoma]

scientific article published on 01 April 1990

[Leukocytoclastic vasculitis: analysis of 62 cases]

scientific article published on 01 March 1987

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