List of works by Axel Behrens

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

scientific article published on 16 January 2017

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

scientific article published on September 2017

ATM signalling and cancer

scientific article

ATMIN defines an NBS1-independent pathway of ATM signalling

scientific article

ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma

scientific article published on May 2011

Absence of the prion protein homologue Doppel causes male sterility

scientific article

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

scientific article (publication date: March 1999)

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH

scientific article published on 27 November 2020

Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation

scientific article published on 26 April 2013

Arginine methylation: making its mark on AP-1 gene activation

scientific article published on 11 July 2013

Bag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis

scientific article

CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth

scientific article published on 04 November 2019

Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

scientific article published on 08 April 2020

Competition between NBS1 and ATMIN controls ATM signaling pathway choice

scientific article published on 6 December 2012

Creating a "Transcampus" in diabetes research between King's College London and the Technische Universität Dresden: update on islet biology and transplantation.

scientific article published on 5 December 2014

DMAP1 is an essential regulator of ATM activity and function

scientific article published on 14 January 2013

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation

scientific article

Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias

scientific article

Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions

scholarly article

Dual regulation of Fbw7 function and oncogenic transformation by Usp28.

scientific article published on 30 October 2014

Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.

scientific article

ERK activation causes epilepsy by stimulating NMDA receptor activity

scientific article

Erratum: Corrigendum: Replication stress links structural and numerical cancer chromosomal instability

scientific article published in Nature

Erratum: RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

scientific article published on 27 June 2016

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor

scientific article published on 2 June 2010

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

scientific article

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

scientific journal article

Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance

scientific article published on 24 September 2015

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.

scientific article published on 10 October 2010

Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions

scientific article

Fbxw7 controls angiogenesis by regulating endothelial Notch activity

scientific article (publication date: 2012)

High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer

scientific article published on 01 February 2021

Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation

scientific article

Impact of genomic damage and ageing on stem cell function

scientific article

Impaired intervertebral disc formation in the absence of Jun.

scientific article published in January 2003

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

scientific article

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation

scientific article published on 17 March 2016

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

scientific article

Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action

scientific article

Integrin signalling regulates YAP and TAZ to control skin homeostasis

scientific article published on 17 March 2016

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

scientific article

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

scientific article (publication date: May 2014)

JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

scientific article published on 11 June 2009

JunB can substitute for Jun in mouse development and cell proliferation

scientific journal article

LUBAC determines chemotherapy resistance in squamous cell lung cancer

scientific article published on 14 January 2019

Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours

scientific article

Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells

scientific article

Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

scientific article published on 21 March 2012

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment

scientific article

NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

scientific article

Paligenosis: prepare to regenerate!

scientific article published on 22 March 2018

Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization

scientific article published on March 2010

Perturbed hematopoiesis in mice lacking ATMIN.

scientific article published on 31 August 2016

Physiological and pathological functions of the prion protein homologue Dpl ⬇️

scientific article published on January 1, 2003

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12

scientific article published on 06 April 2021

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

scientific article published on 9 November 2015

Replication stress links structural and numerical cancer chromosomal instability

scientific article published on February 2013

Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain

scientific article

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

scientific article

Specific pathophysiological functions of JNK isoforms in the brain

scientific article published in January 2005

Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease

scientific article published on 08 April 2015

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration

scientific journal article

The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain

scientific article

The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling

scientific article

The F-box protein Fbw7 is required for cerebellar development

scientific article published on 29 July 2011

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer

scientific article

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

scientific article

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

scientific article

UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function

scientific article

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer

scientific article published on 19 April 2022

Usp28 counteracts Fbw7 in intestinal homeostasis and cancer

scientific article

Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer

scientific article published on 06 March 2012

YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling

scientific article published on 20 May 2016

c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea.

scientific article

c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

scientific article published on 2 January 2011

c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling.

scientific article

c-Jun is a negative regulator of myelination.

scientific article published on May 2008

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration

scientific article

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