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List of works by Charles Keller

18F‐FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models ⬇️

scientific article published on January 11, 2012

A Postnatal Pax7 Progenitor Gives Rise to Pituitary Adenomas.

scientific article

A Urea Cycle Defect Presenting as Acute Cerebellar Ataxia in a 3-Year-Old Girl ⬇️

scientific article published on 01 February 1998

AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell

scientific article published in March 2012

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

scientific article published on 15 October 2004

An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma

scientific article published on 30 August 2012

BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration

scientific journal article

Biomarker system for studying muscle, stem cells, and cancer in vivo.

scientific article published on 30 March 2009

Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.

scientific article

Bortezomib stabilizes NOXA and triggers ROS-associated apoptosis in medulloblastoma.

scientific article published on 3 June 2011

CCAAT/Enhancer Binding Protein Beta is Expressed in Satellite Cells and Controls Myogenesis

scientific article published on 01 December 2012

CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells.

scientific article published on 11 January 2012

Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma

scientific article published on 12 June 2020

Congenital Myotonic Dystrophy Requiring Prolonged Endotracheal and Noninvasive Assisted Ventilation: Not a Uniformly Fatal Condition ⬇️

scientific article published on April 1, 1998

Constitutive Notch activation upregulates Pax7 and promotes the self-renewal of skeletal muscle satellite cells

scientific article

Contrast enhanced vessel imaging using microCT.

scientific article published on 27 January 2011

Craniorachischisis and omphalocele in a stillborn cynomolgus monkey (Macaca fascicularis).

scientific article published on 12 May 2011

Crimson carrier, a long-acting contrast agent for in vivo near-infrared imaging of injured and diseased muscle

scientific article published on August 2010

Deep Functional and Molecular Characterization of a High-Risk Undifferentiated Pleomorphic Sarcoma

scientific article published on 04 May 2020

Defining an embryonal rhabdomyosarcoma endotype

scientific article published on 01 April 2020

Defining the Extracellular Matrix of Rhabdomyosarcoma

scientific article published on 23 February 2021

Developmental origins of fusion-negative rhabdomyosarcomas.

scientific article published on January 2011

Disseminated Mycobacterium avium complex presenting as hematochezia in an infant with rapidly progressive acquired immunodeficiency syndrome

scientific article published on 01 August 1996

Effective fiber hypertrophy in satellite cell-depleted skeletal muscle.

scientific article

Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma

scientific article

Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma

scientific article

FOXO1 couples metabolic activity and growth state in the vascular endothelium

scientific article published on 06 January 2016

Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion.

scientific article

High-throughput detection of glutathione s-transferase polymorphic alleles in a pediatric cancer population

scientific article published in February 2004

IGF-1 receptor inhibition by picropodophyllin in medulloblastoma

scientific article published on 6 August 2010

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma.

scientific article published on 5 April 2018

IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma

scientific article

Images in cardiovascular medicine: Microscopic computed tomography-based virtual histology for visualization and morphometry of atherosclerosis in diabetic apolipoprotein e mutant mice

scientific article

Immune Competency of a Hairless Mouse Strain for Improved Preclinical Studies in Genetically Engineered Mice ⬇️

scientific article published on July 27, 2010

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

scientific article (publication date: 10 August 2007)

Insights into pediatric rhabdomyosarcoma research: Challenges and goals

scientific article published on 21 June 2019

Low-grade myofibrosarcoma of the head and neck: importance of surgical therapy

scientific article published on 01 February 2004

MicroCT-based virtual histology evaluation of preclinical medulloblastoma.

scientific article published on June 2011

Multimodality Chamber for coregistered anatomical and molecular imaging of small animals

scientific article published on 01 September 2007

MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells

scientific article published on March 2011

Near-infrared imaging of injured tissue in living subjects using IR-820.

scientific article published on January 2009

Overcoming autopsy barriers in pediatric cancer research.

scientific article

PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma

scientific article

Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin.

scientific article

Pax7 expressing cells contribute to dermal wound repair, regulating scar size through a β-catenin mediated process.

scientific article

Personalized cancer care: opportunities and challenges in pediatric neuro-oncology

scientific article published on 9 December 2011

Preclinical rationale for entinostat in embryonal rhabdomyosarcoma

scientific article published on 21 May 2019

Preclinical testing of erlotinib in a transgenic alveolar rhabdomyosarcoma mouse model.

scientific article

Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model.

scientific article published in March 2012

Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.

scientific article

Purinergic Receptor Stimulation Reduces Cytotoxic Edema and Brain Infarcts in Mouse Induced by Photothrombosis by Energizing Glial Mitochondria ⬇️

scientific article published on December 22, 2010

Rb1 gene inactivation expands satellite cell and postnatal myoblast pools

scientific article

Refinement of a morphological scoring system for postimplantation rabbit conceptuses

scientific article published in June 2007

Renal stem cell biology starts to take spherical shape. Commentary on: Lusis et al., Isolation of clonogenic, long-term self renewing embryonic renal stem cells.

scientific article

Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group

scientific article published on March 2006

Secreted meningeal chemokines, but not VEGFA, modulate the migratory properties of medulloblastoma cells.

scientific article

Severe runting in a laboratory mouse (Mus musculus)

scientific article published on 01 January 2007

Shape analysis of the basioccipital bone in Pax7-deficient mice.

scientific article published on 20 December 2017

Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.

scientific article published on 31 July 2009

Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.

scientific article published in June 2010

The HDAC3–SMARCA4–miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma

scientific article published on 20 November 2018

The long road to immunotherapy for childhood rhabdomyosarcoma

scientific article published on 08 July 2011

The not-so-skinny on muscle cancer

scientific article published on October 2012

Thermal windows on Brazilian free-tailed bats facilitate thermoregulation during prolonged flight

scientific article published on 4 May 2010

Translational inhibition of messenger RNA of the human pi class glutathione S-transferase by antisense oligodeoxyribonucleotides

scientific article published in April 1998

Undifferentiated small round cell sarcoma in a young male: a case report

scientific article published on 03 February 2020

Vascular contrast enhanced micro-CT imaging of "radiators" in the Brazilian free-tailed bat (Tadarida brasiliensis).

scientific article published on 26 January 2012

Virtual histology of transgenic mouse embryos for high-throughput phenotyping.

scientific article

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