List of works - Yongjun Guan

An intact U5-leader stem is important for efficient replication of simian immunodeficiency virus.

scientific article

Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial

scientific article

Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia

scientific article

Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.

scientific article published on 28 June 2013

Contribution of V(H) replacement products to the generation of anti-HIV antibodies

scientific article published on 15 November 2012

Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activity.

scientific article

DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques

scientific article

DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge

scientific article published on 28 January 2013

Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection

scientific article

Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

scientific article

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies

scientific article published on 29 August 2012

Epitope target structures of Fc-mediated effector function during HIV-1 acquisition

scientific article

Hydrophobic amino acids in the human immunodeficiency virus type 1 p2 and nucleocapsid proteins can contribute to the rescue of deleted viral RNA packaging signals.

scientific article published on August 2001

IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques

scientific article published on 16 August 2012

Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins

scientific article published on 12 October 2011

Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1.

scientific article

Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

scientific article published on 18 December 2013

Leader sequences downstream of the primer binding site are important for efficient replication of simian immunodeficiency virus

scientific article

Novel, live attenuated simian immunodeficiency virus constructs containing major deletions in leader RNA sequences

scientific article

Partial restoration of replication of simian immunodeficiency virus by point mutations in either the dimerization initiation site (DIS) or Gag region after deletion mutagenesis within the DIS.

scientific article

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure

scientific article published on 16 January 2013

Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120.

scientific article

Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands

scientific article

Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasma.

scientific article

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

scientific article (publication date: November 2014)

Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins.

scientific article published on 24 March 2007

The M184V mutation in reverse transcriptase can delay reversion of attenuated variants of simian immunodeficiency virus.

scientific article

The first structure of HIV-1 gp120 with CD4 and CCR5 receptors

article

Vaccination with Vaxfectin®adjuvanted SIV DNA induces long-lasting humoral immune responses able to reduce SIVmac251 Viremia ⬇️

scientific article published on 02 July 2013

List of works by Yongjun Guan

An intact U5-leader stem is important for efficient replication of simian immunodeficiency virus.

Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial

Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia

Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.

Contribution of V(H) replacement products to the generation of anti-HIV antibodies

Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activity.

DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques

DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge

Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection

Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies

Epitope target structures of Fc-mediated effector function during HIV-1 acquisition

Hydrophobic amino acids in the human immunodeficiency virus type 1 p2 and nucleocapsid proteins can contribute to the rescue of deleted viral RNA packaging signals.

IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques

Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins

Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1.

Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

Leader sequences downstream of the primer binding site are important for efficient replication of simian immunodeficiency virus

Novel, live attenuated simian immunodeficiency virus constructs containing major deletions in leader RNA sequences

Partial restoration of replication of simian immunodeficiency virus by point mutations in either the dimerization initiation site (DIS) or Gag region after deletion mutagenesis within the DIS.

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure

Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120.

Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands

Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasma.

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins.

The M184V mutation in reverse transcriptase can delay reversion of attenuated variants of simian immunodeficiency virus.

The first structure of HIV-1 gp120 with CD4 and CCR5 receptors

Vaccination with Vaxfectin®adjuvanted SIV DNA induces long-lasting humoral immune responses able to reduce SIVmac251 Viremia ⬇️