List of works - Maria Thomas

A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

scientific article

A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells

scientific article

Activating and Inhibitory Functions of WNT/β-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells

scientific article

Adenoviral overexpression of Lhx2 attenuates cell viability but does not preserve the stem cell like phenotype of hepatic stellate cells

scientific article published on July 2014

Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists

scientific article published on 26 August 2015

Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

scientific article

Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).

scientific article published on 7 January 2013

Genetics, epigenetics, and regulation of drug-metabolizing cytochrome p450 enzymes.

scientific article

Hepatocyte fate upon TGF-β challenge is determined by the matrix environment.

scientific article

Impact of FLT3 mutations and secondary cytogenetic changes on the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with a single agent arsenic trioxide regimen

scientific article published in July 2007

Inferring statin-induced gene regulatory relationships in primary human hepatocytes

scientific article published on 14 July 2011

Interleukin-1β enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes

scientific article published on 31 December 2014

LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods

scientific article

Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.

scientific article

Oncostatin M regulates SOCS3 mRNA stability via the MEK-ERK1/2-pathway independent of p38(MAPK)/MK2.

scientific article published on 3 January 2015

PPARA: a novel genetic determinant of CYP3A4 in vitro and in vivo

scientific article

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

scientific article published on 20 November 2015

Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained.

scientific article

Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.

scientific article

Targeting nuclear receptors with lentivirus-delivered small RNAs in primary human hepatocytes.

scientific article

The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

scientific article published on 30 June 2015

Virtual pathway explorer (viPEr) and pathway enrichment analysis tool (PEANuT): creating and analyzing focus networks to identify cross-talk between molecules and pathways

scientific article published on 14 October 2015

List of works by Maria Thomas

A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells

Activating and Inhibitory Functions of WNT/β-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells

Adenoviral overexpression of Lhx2 attenuates cell viability but does not preserve the stem cell like phenotype of hepatic stellate cells

Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists

Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).

Genetics, epigenetics, and regulation of drug-metabolizing cytochrome p450 enzymes.

Hepatocyte fate upon TGF-β challenge is determined by the matrix environment.

Impact of FLT3 mutations and secondary cytogenetic changes on the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with a single agent arsenic trioxide regimen

Inferring statin-induced gene regulatory relationships in primary human hepatocytes

Interleukin-1β enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes

LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods

Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.

Oncostatin M regulates SOCS3 mRNA stability via the MEK-ERK1/2-pathway independent of p38(MAPK)/MK2.

PPARA: a novel genetic determinant of CYP3A4 in vitro and in vivo

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained.

Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.

Targeting nuclear receptors with lentivirus-delivered small RNAs in primary human hepatocytes.

The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

Virtual pathway explorer (viPEr) and pathway enrichment analysis tool (PEANuT): creating and analyzing focus networks to identify cross-talk between molecules and pathways