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List of works by Erik Wiemer

A pharmacogenetic predictive model for paclitaxel clearance based on the DMET platform

scientific article published on 5 August 2013

A small mammal model of tumour implantation, dissemination and growth factor expression after partial hepatectomy.

scientific article published on 17 April 2007

Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis

scientific article published on 12 June 2019

Absence of mutations in the deoxycytidine kinase (dCK) gene in patients with relapsed and/or refractory acute myeloid leukemia (AML).

scientific article published in May 2001

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.

scientific article published on 17 May 2019

CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.

scientific article published on 02 May 2013

Can "specific" OCT1 inhibitors be used to determine OCT1 transporter activity toward imatinib?

scientific article published in June 2013

Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest

scientific article published on 13 March 2020

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

scientific article published on 7 June 2015

Cross-resistance between taxanes and new hormonal agents abiraterone and enzalutamide may affect drug sequence choices in metastatic castration-resistant prostate cancer.

scientific article published on 24 October 2013

DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity

scientific article

Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors

scientific article published on 19 February 2020

Dose selection in phase I studies: why we should always go for the top

scientific article published on 10 March 2008

Early cessation of the clinical development of LiPlaCis, a liposomal cisplatin formulation.

scientific article

Editorial: the long and winding road to better cancer cell-specific therapies

scientific article published on 01 May 2008

Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: a prospective cross-over drug-drug interaction study.

scientific article

Effects of methimazole on the elimination of irinotecan.

scientific article

Evaluation of patient enrollment in oncology phase I clinical trials.

scientific article

Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.

scientific article

Fasting protects against the side effects of irinotecan treatment but does not affect anti-tumour activity in mice

scientific article published on 29 August 2015

Host resistance to lung infection mediated by major vault protein in epithelial cells

scientific article

Identification of multidrug resistance-associated protein 1 and glutathione as multidrug resistance mechanisms in human prostate cancer cells: chemosensitization with leukotriene D4 antagonists and buthionine sulfoximine.

scientific article published on June 2004

Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment

scientific article published in June 2007

Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

scientific article published on 9 December 2013

Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)

scientific article (publication date: May 2002)

Inducible Major Vault Protein Plays a Pivotal Role in Double-Stranded RNA- or Virus-Induced Proinflammatory Response.

scientific article published on 3 February 2016

Influence of smoking on the pharmacokinetics and toxicity profiles of taxane therapy

scientific article published on 29 May 2012

Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting

scientific article published on 08 July 2019

Isolation and characterization of Pas2p, a peroxisomal membrane protein essential for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris.

scientific article published in August 1996

Kinetics of the assembly of peroxisomes after fusion of complementary cell lines from patients with the cerebro-hepato-renal (Zellweger) syndrome and related disorders

scientific article published on 01 May 1988

Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer.

scientific article

Loss of SLCO1B3 drives taxane resistance in prostate cancer

scientific article published on 18 August 2016

MDR1 expression in poor-risk acute myeloid leukemia with partial or complete monosomy 7.

scientific article

MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia

scientific article published in June 2001

Macrocytosis as a potential parameter associated with survival after tyrosine kinase inhibitor treatment.

scientific article published on 31 January 2016

Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation

scientific article published on 17 April 2019

Major vault protein, a candidate gene in 16p11.2 microdeletion syndrome, is required for the homeostatic regulation of visual cortical plasticity.

scientific article published on 14 March 2018

Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells

scientific article published in July 2005

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours

scientific article published on 22 August 2013

MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells

scientific article published on 15 February 2016

MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma

scientific article published on 23 January 2020

MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors.

scientific article published on 16 January 2014

MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation

scientific article

MicroRNA regulation of RAD51 in serous ovarian cancer modulates chemotherapy response

scientific article published on 20 May 2015

MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α

scientific article

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

scientific article published on 18 June 2009

MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines

scientific article published on 07 May 2019

MicroRNAs in ovarian cancer biology and therapy resistance.

scientific article

Multiple human vault RNAs. Expression and association with the vault complex

scientific article

Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors

scientific article published on 22 September 2020

Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

scientific article

Phase I study of RGB-286638, a novel, multitargeted cyclin-dependent kinase inhibitor in patients with solid tumors

scientific article published on 14 July 2014

Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area

scientific article

Phenotypic heterogeneity in cultured skin fibroblasts from patients with disorders of peroxisome biogenesis belonging to the same complementation group

scientific article published on October 1991

Pitfalls of the application of microdialysis in clinical oncology: controversial findings with docetaxel.

scientific article

Practical aspects of managing gastrointestinal stromal tumors.

scientific article published in November 2006

Prenatal diagnosis of Zellweger syndrome by direct visualization of peroxisomes in chorionic villus fibroblasts by immunofluorescence microscopy

scientific article published in January 1989

Production and characterisation of monoclonal antibodies against native and disassembled human catalase

scientific article published on 01 July 1992

Prognostic Circulating MicroRNA Biomarkers in Early-Stage Non-Small Cell Lung Cancer: A Role for miR-150.

scientific article published on 29 December 2017

Quantification of cabazitaxel in human plasma by liquid chromatography/triple-quadrupole mass spectrometry: A practical solution for non-specific binding ⬇️

scientific article published on October 24, 2011

Quantification of tamoxifen and three of its phase-I metabolites in human plasma by liquid chromatography/triple-quadrupole mass spectrometry ⬇️

scientific article published on August 5, 2011

Relationship Between Sunitinib Pharmacokinetics and Administration Time: Preclinical and Clinical Evidence.

scientific article published in August 2015

Renal function as a predictor of irinotecan-induced neutropenia.

scientific article

Reply to Masaki Shiota and Akira Yokomizo's Letter to the Editor re: Robert J. van Soest, Ellen S. de Morrée, Charlotte F. Kweldam, et al. Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not C

scientific article published on 30 July 2015

Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.

scientific article published on July 2004

Selection and characterisation of a phage-displayed human antibody (Fab) reactive to the lung resistance-related major vault protein

scientific article

Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry ⬇️

scientific article published on September 21, 2010

Stressed tumor cell, chemosensitized cancer ⬇️

scientific article published on December 6, 2011

Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not Cabazitaxel, in Castration-resistant Prostate Cancer

scientific article published on 4 December 2014

The applicability of mTOR inhibition in solid tumors.

scientific article

The electrochemical proton gradient in the bloodstream form of Trypanosoma brucei is dependent on the temperature

scientific article published on October 1, 1992

The formation of vault-tubes: a dynamic interaction between vaults and vault PARP.

scientific article published on 16 September 2003

The genomic sequence of the murine major vault protein and its promoter

scientific article published in July 2002

The issue of non-specific binding of cabazitaxel

scientific article published on 17 June 2013

The kinase RSK2 modulates the sensitivity of ovarian cancer cells to cisplatin.

scientific article

The role of microRNAs in cancer: no small matter.

scientific article published on 24 May 2007

The vault complex

scientific article (publication date: September 2003)

The versatile nature of miR-9/9* in human cancer

scientific article published on 17 April 2018

Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21

scientific article published on 05 January 2019

Understanding taxanes in prostate cancer; importance of intratumoral drug accumulation.

scientific article published on 21 March 2016

Unimpaired dendritic cell functions in MVP/LRP knockout mice

scientific article published in September 2003

Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen ⬇️

scientific article published on June 13, 2013

Vaults: a ribonucleoprotein particle involved in drug resistance? ⬇️

scientific article (publication date: 20 October 2003)

Visualization of the peroxisomal compartment in living mammalian cells: dynamic behavior and association with microtubules.

scientific article

Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations

scientific article published on 18 October 2018

miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells ⬇️

scientific article published on October 8, 2012

miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway.

scientific article

miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs

scientific article published on 19 April 2013

microRNAs in stage I epithelial ovarian cancer

scientific article published on 21 February 2011

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