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List of works by Sabine L. Flitsch

'One-pot' sequential enzymatic modification of synthetic glycolipids in vesicle membranes.

scientific article published on 19 January 2018

2-Pyridylfuran: A New Fluorescent Tag for the Analysis of Carbohydrates

article

A Bifunctional Spin Label for Ligand Recognition on Surfaces

scientific article published on June 2017

A Careful Consideration of the Influence of Structure, Partial charges and Basis Sets on Collision Cross Sections of Monosaccharides when Comparing Values from DFT Calculated Conformers to those Obtained Experimentally

article published in 2017

A novel method for the specific glycosylation of proteins

A promiscuous glycosyltransferase generates poly-β-1,4-glucan derivatives that facilitate mass spectrometry-based detection of cellulolytic enzymes

scientific article published on 30 June 2021

A recycling pathway for cyanogenic glycosides evidenced by the comparative metabolic profiling in three cyanogenic plant species

scientific article

A self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center

scientific article (publication date: 5 December 2003)

A versatile gold surface approach for fabrication and interrogation of glycoarrays

scientific article

A versatile route to edge-specific modifications to pristine graphene by electrophilic aromatic substitution

scientific article published on 09 May 2020

Accelerated Enzymatic Galactosylation of N-Acetylglucosaminolipids in Lipid Microdomains

scientific article published on 30 July 2012

Active site diversification of P450cam with indole generates catalysts for benzylic oxidation reactions

scientific article published on 22 September 2015

Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides

scientific article

Advancing Solutions to the Carbohydrate Sequencing Challenge

scientific article published on 21 August 2019

An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclic beta-Diketones This work was supported by the BBSRC (grants to N.J.T. and S.L.F.) and the European Commission (grant to J.G.). We also thank Mr. J. Millar and D

scientific article published on 01 March 2001

An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclicβ-Diketones

scientific article published on 16 March 2001

An Efficient Synthetic Route to Glycoamino Acid Building Blocks for Glycopeptide Synthesis

scientific article published on 01 October 2004

An Enzymatic N-Acylation Step Enables the Biocatalytic Synthesis of Unnatural Sialosides

scientific article published on 03 February 2020

Analysis of the domain properties of the novel cytochrome P450 RhF.

scientific article

Application of Biocatalysis to on-DNA Carbohydrate Library Synthesis.

scientific article

Application of carbohydrate arrays coupled with mass spectrometry to detect activity of plant-polysaccharide degradative enzymes from the fungus Aspergillus niger

scientific article published on 21 February 2017

Applications of a highly α2,6-selective pseudosialidase.

scientific article published on 28 February 2018

Applications of ion mobility mass spectrometry for high throughput, high resolution glycan analysis.

scientific article published on 4 February 2016

Assessing the cluster glycoside effect during the binding of concanavalin A to mannosylated artificial lipid rafts

scientific article published on 26 October 2009

Automated glycan assembly of type 14 capsular polysaccharide fragments

scientific article published on 19 June 2020

Baeyer-Villiger Oxidations

Biocatalysis

scientific article published on 24 June 2021

Biocatalysis in Asia and the Pacific

scientific article published on 26 August 2024

Biocatalytic Cascades toward Iminosugar Scaffolds Reveal Promiscuous Activity of Shikimate Dehydrogenases

scientific article published on 25 January 2023

Biocatalytic Oxidation in Continuous Flow for the Generation of Carbohydrate Dialdehydes ⬇️

scholarly article

Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

scientific article published on 07 April 2020

Biochemical characterisation of the neuraminidase pool of the human gut symbiont Akkermansia muciniphila

scientific article published on 14 August 2015

Biochemical correlation of activity of the α-dystroglycan-modifying glycosyltransferase POMGnT1 with mutations in muscle-eye-brain disease.

scientific article

Biocompatible functionalisation of starch

scientific article published on 22 November 2010

Biological and biochemical properties of two Xenopus laevis N-acetylgalactosaminyltransferases with contrasting roles in embryogenesis.

scientific article published on 23 October 2014

Bi‐enzymatic Conversion of Cinnamic Acids to 2‐Arylethylamines

scientific article published on 2 January 2020

Bottom-Up Elucidation of Glycosidic Bond Stereochemistry.

scientific article published on 28 March 2017

COS-1 cell expression and one-step affinity protein purification and activity of epitope-tagged human erythropoietin and of site-directed mutants

scientific article published on 01 June 1997

Cell-specific bioorthogonal tagging of glycoproteins

scientific article published on 25 October 2022

Characterisation of CYP102A25 from B. marmarensis and CYP102A26 from P. halophilus: P450 homologues of BM3 with preference towards hydroxylation of medium chain fatty acids

scientific article published on 8 December 2017

Characterisation of a Bacterial Galactokinase with High Activity and Broad Substrate Tolerance for Chemoenzymatic Synthesis of 6-Aminogalactose-1-Phosphate and Analogues

scientific article published on 29 November 2017

ChemInform Abstract: An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclic β-Diketones

ChemInform Abstract: Copper-Catalyzed Double Additions and Radical Cyclization Cascades in the Re-Engineering of the Antibacterial Pleuromutilin

article

ChemInform Abstract: Cytochromes P450 as Useful Biocatalysts: Addressing the Limitations

ChemInform Abstract: Enzymatic Reactions on Immobilized Substrates

ChemInform Abstract: Enzyme Cleavable Linker Units

ChemInform Abstract: Straightforward Synthesis of 2-Acetamido-2-deoxy-β-D-glucopyranosyl Esters under Microwave Conditions

Chemo-enzymatic synthesis of a β-mannosyl-containing trisaccharide

Chemoenzymatic Synthesis of Optically Pure l- and d-Biarylalanines through Biocatalytic Asymmetric Amination and Palladium-Catalyzed Arylation

scholarly article by Syed T. Ahmed et al published 13 August 2015 in ACS Catalysis

Chemoenzymatic synthesis of 3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates

scientific article published on 11 May 2020

Chemoenzymatic synthesis of O-mannosylpeptides in solution and on solid phase

scientific article published in March 2012

Chemoenzymatic synthesis of sialooligosaccharides on arrays for studies of cell surface adhesion

scientific article

Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope

scientific article published on 2 November 2011

Cloning, expression and characterisation of P450-Hal1 (CYP116B62) from Halomonas sp. NCIMB 172: A self-sufficient P450 with high expression and diverse substrate scope.

scientific article published on 17 February 2018

Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathways

article

Controlling protein retention on enzyme-responsive surfaces

scientific article published on November 2006

Copper-Catalyzed Double Additions and Radical Cyclization Cascades in the Re-Engineering of the Antibacterial Pleuromutilin

scientific article published on 3 November 2015

Cytochromes P450 as useful biocatalysts: addressing the limitations

scientific article published on 24 January 2011

Design, synthesis and assaying of potential aquaporin inhibitors.

scientific article published on January 2009

Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome

scientific article published on 3 December 2012

Development and application of a highly α2,6-selective pseudosialidase

Development of Continuous Flow Systems to Access Secondary Amines Through Previously Incompatible Biocatalytic Cascades

scientific article published on 16 August 2021

Development of a Solid Phase Array Assay for the Screening of Galactose Oxidase Activity and for Fast Identification of Inhibitors.

scientific article published on 24 July 2017

Development of recombinant, immobilised β-1,4-mannosyltransferase for use as an efficient tool in the chemoenzymatic synthesis of N-linked oligosaccharides

article

Discovery and Biochemical Characterization of a Thermostable Glucose-1-phosphate Nucleotidyltransferase from Thermodesulfatator indicus.

scientific article published on 24 July 2017

Discovery of novel human aquaporin-1 blockers

scientific article published on 7 November 2012

Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing.

scientific article published on 8 December 2013

Drug Discovery and Development

scientific article published on 26 February 2024

Dual purpose S-trityl-linkers for glycoarray fabrication on both polystyrene and gold

scientific article published in November 2012

Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways

scientific article

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum

scientific article

Effect of microwave radiation on enzymatic and chemical Peptide bond synthesis on solid phase

scientific article published on 25 March 2009

Efficient terpene hydroxylation catalysts based upon P450 enzymes derived from actinomycetes

scientific article published on 7 July 2005

Enantioselective Benzylic Hydroxylation Catalysed by P450 Monooxygenases: Characterisation of a P450cam Mutant Library and Molecular Modelling

scientific article published on 23 December 2015

Engineered Ammonia Lyases for the Production of Challenging Electron-Rich l-Phenylalanines

article published in 2018

Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme.

scientific article

Enzymatic Building Block Synthesis for Automated Solid Phase Glycan Assembly

scientific article published on 28 August 2020

Enzymatic Late-Stage Modifications: Better Late Than Never

scientific article

Enzymatic Synthesis of Trideuterated Sialosides

scientific article published on 08 April 2019

Enzymatic amine acyl exchange in peptides on gold surfaces

scientific article

Enzymatic elaboration of oxime-linked glycoconjugates in solution and on liposomes

Enzymatic generation and in situ screening of a dynamic combinatorial library of sialic acid analogues

scientific article

Enzymatic glycosylation of peptide arrays on gold surfaces

scientific article

Enzymatic glycosylations on arrays

scientific article

Enzymatic optical resolution via acylation–hydrolysis on a solid support

scientific article published on 01 February 2003

Enzymatic reactions on immobilised substrates

scientific article

Enzymatic synthesis of N-acetyllactosamine from lactose enabled by recombinant β1,4-galactosyltransferases

scientific article published on 01 June 2019

Enzymatic synthesis of a new type of penicillin

article

Enzymatic synthesis of colorimetric substrates to determine α-2,3- and α-2,6-specific neuraminidase activity

scholarly article in RSC Advances, vol. 3 no. 44, 2013

Enzymatic synthesis of peptides on a solid support

scientific article published on 09 December 2008

Enzymatischer Amin-Acyl-Austausch in Peptiden auf Gold-Oberflächen

article published in 2012

Enzyme Cascades in Whole Cells for the Synthesis of Chiral Cyclic Amines

article

Enzyme catalysis on solid surfaces

scientific article published on 20 April 2008

Enzyme-catalyzed formation of glycosidic linkages

scientific article

Enzyme-cleavable linkers for peptide and glycopeptide synthesis

scientific article published on 16 June 2005

Enzymkatalysierte späte Modifizierungen: Besser spät als nie

scientific article published on 26 July 2021

Evidence That Bilayer Bending Rigidity Affects Membrane Protein Folding†

article

Exploiting the Disialyl Galactose Activity of α2,6-Sialyltransferase from Photobacterium damselae To Generate a Highly Sialylated Recombinant α-1-Antitrypsin

scientific article published on 11 October 2019

Expression and mutagenesis of recombinant human and murine erythropoietins in Escherichia coli

article

Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS.

scientific article published on 21 May 2012

Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug-to-Antibody Ratios

Ganzzellen-Biokatalysator für stereoselektive C-H-Aminierungen

Generation of a dynamic combinatorial library using sialic acid aldolase and in situ screening against wheat germ agglutinin

Glycoarrays—tools for determining protein–carbohydrate interactions and glycoenzyme specificity

scientific article published on 05 August 2008

Glycoprotein labeling using engineered variants of galactose oxidase obtained by directed evolution

scientific article

Glycosylation characterization of human and porcine fibrinogen proteins by lectin-binding biophotonic microarray imaging.

scientific article

Glycosylation with a twist

scientific article published in Nature

Heavily fluorinated carbohydrates as enzyme substrates: oxidation of tetrafluorinated galactose by galactose oxidase

scientific article published on 13 September 2011

High-throughput chemical and chemoenzymatic approaches to saccharide-coated magnetic nanoparticles for MRI

scientific article published on 11 September 2019

Highly site-selective stability increases by glycosylation of dihydrofolate reductase

scientific article published in May 2010

IRMPD Spectroscopy Sheds New (Infrared) Light on the Sulfate Pattern of Carbohydrates

scientific article

Identification of a new class of cytochrome P450 from a Rhodococcus sp.

scientific article

Improved biotransformations on charged PEGA supports

scientific article published on 01 June 2003

In Vitro Sialylation of Recombinant Alpha-1-Antitrypsin using α2,6 Sialyltransferase from Photobacterium Damselae Produces Di-sialyl Galactose Motifs in N-Glycans

In vivo anti-malarial effect of the beta-amino alcohol 1t on Plasmodium berghei.

scientific article

Increased thermal stability of site-selectively glycosylated dihydrofolate reductase

scientific article published in August 2005

Increasing the diversity of biocatalytic reactions

scientific article published on 19 February 2011

Inexpensive and fast pathogenic bacteria screening using field-effect transistors

scientific article

Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response

scientific article published on March 2012

Innentitelbild: Ganzzellen-Biokatalysator für stereoselektive C-H-Aminierungen (Angew. Chem. 4/2016)

Inside Cover: Whole-Cell Biocatalysts for Stereoselective C−H Amination Reactions (Angew. Chem. Int. Ed. 4/2016)

Intermediates in the folding of the membrane protein bacteriorhodopsin

scientific article published on 01 February 1995

Introduction of permanently charged groups into PEGA resins leads to improved biotransformations on solid support

Introduction to Glycosylation: new methodologies and applications

scientific article published on 10 September 2020

Kinetics of enzyme attack on substrates covalently attached to solid surfaces: influence of spacer chain length, immobilized substrate surface concentration and surface charge

scientific article published on 26 September 2008

LICRED: a versatile drop-in vector for rapid generation of redox-self-sufficient cytochrome P450s

scientific article

Label-Free Discovery Array Platform for the Characterization of Glycan Binding Proteins and Glycoproteins.

scientific article

Lipase-catalysed acylation of starch and determination of the degree of substitution by methanolysis and GC.

scientific article

Lipase-catalyzed kinetic resolution on solid-phase via a "capture and release" strategy

scientific article published in November 2003

MALDI-ToF MS analysis of glycosyltransferase activities on gold surface arrays

scientific article

Microwave-assisted ring opening of epoxides: a general route to the synthesis of 1-aminopropan-2-ols with anti malaria parasite activities

scientific article

Natural heterogeneous catalysis with immobilised oxidase biocatalysts

scientific article published on 20 May 2020

New Chemical Tools for Diagnosis and Treatment of Cancer

scientific article published on 23 May 2022

Novel Mechanism of Inhibition of Elastase by β-Lactams Is Defined by Two Inhibitor Crystal Complexes

scientific article published in Journal of Biological Chemistry

Nucleotide sequence of a portion of the camphor-degrading gene cluster from Rhodococcus sp. NCIMB 9784.

scientific article published on April 2004

One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA), and Imine Reductase (IRED) Biocatalysts

article

One-Step Biocatalytic Synthesis of Sustainable Surfactants by Selective Amide Bond Formation

scientific article published on 25 July 2022

Optimized polymer-enzyme electrostatic interactions significantly improve penicillin G amidase efficiency in charged PEGA polymers

scientific article published in January 2005

Organically modified xerogels as supports for solid-phase chemistry

Oxo-ester mediated native chemical ligation on microarrays: an efficient and chemoselective coupling methodology

scientific article published on 28 March 2012

Oxygenation of CH and CC Bonds

P450(camr), a cytochrome P450 catalysing the stereospecific 6- endo-hydroxylation of (1 R)-(+)-camphor.

scientific article

Panel of New Thermostable CYP116B Self-Sufficient Cytochrome P450 Monooxygenases that Catalyze C−H Activation with a Diverse Substrate Scope

Penicillin biosynthesis: active site mapping with aminoadipoylcysteinylvaline variants

article

Penicillin biosynthesis: structure–reactivity profile of unsaturated substrates for isopenicillin N synthetase

Penicillin biosynthesis: the origin of hydroxy groups in β-lactams derived from unsaturated substrates

Phytanyl-pyrophosphate-linked substrate for a bacterial alpha-mannosyltransferase.

scientific article published in May 2000

Preparation of aminoethyl glycosides for glycoconjugation

scientific article published on 29 July 2010

Probing the substrate specificity of the catalytically self-sufficient cytochrome P450 RhF from a Rhodococcus sp

article

Profiling Glycosyltransferase Activities by Tritium Imaging of Glycan Microarrays

scientific article published on 08 April 2013

Profiling Primary Protease Specificity by Peptide Synthesis on a Solid Support

scientific article published on 01 June 2004

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-Fluorinated Monosaccharides

scholarly article published 9 March 2020

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides

scientific article published on 30 June 2020

Protease-catalyzed peptide synthesis on solid support

scientific article published in September 2002

Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action

scientific article published on 21 March 2006

Rapid Screening of Diverse Biotransformations for Enzyme Evolution

scientific article published on 26 April 2021

Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry

scientific article published on 21 March 2016

Rapid and ultra-sensitive determination of enzyme activities using surface-enhanced resonance Raman scattering

scientific article published on 08 August 2004

Real-Time Imaging of Protease Action on Substrates Covalently Immobilised to Polymer Supports

scientific article published on June 2007

Real-Time Screening of Biocatalysts in Live Bacterial Colonies.

scientific article

Regio- and Enantio-selective Chemo-enzymatic C−H-Lactonization of Decanoic Acid to (S )-δ-Decalactone

scientific article published on 26 March 2019

Regio- and stereoselective oxidation of unactivated C-H bonds with Rhodococcus rhodochrous

scientific article published on 3 April 2012

Regio‐ and Enantio‐selective Chemo‐enzymatic C−H‐Lactonization of Decanoic Acid to ( S )‐δ‐Decalactone

Retinal Binding during Folding and Assembly of the Membrane Protein Bacteriorhodopsin†

scientific article published on 01 May 1996

RetroBioCat as a computer-aided synthesis planning tool for biocatalytic reactions and cascades

scientific article published in February 2021

S-linked sugars lost and found

article

SPOT synthesis of peptide arrays on self-assembled monolayers and their evaluation as enzyme substrates

scientific article

Selective Oxidation of N -Glycolylneuraminic Acid Using an Engineered Galactose Oxidase Variant

scientific article published on 5 August 2019

Selective in vitro glycosylation of recombinant proteins: semi-synthesis of novel homogeneous glycoforms of human erythropoietin

scientific article published in February 2001

Sialylation of lactosyl lipids in membrane microdomains by T. cruzi trans-sialidase

scientific article published on December 2014

Slow α Helix Formation during Folding of a Membrane Protein†

scientific article published on 01 January 1997

Solid-phase synthesis of thioether-linked glycopeptide mimics for application to glycoprotein semisynthesis

scientific article

Straightforward Synthesis of 2-Acetamido-2-deoxy-β-d-glucopyranosyl Esters under Microwave Conditions

Substrate promiscuity of cytochrome P450 RhF

Sugars tied to the spot

scientific article

Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays

article

Synthesis and modifications of carbohydrates, using biotransformations

scientific article published on April 2004

Synthesis and screening of a library of Lewis deoxyfluoro-analogues reveals differential recognition by glycan-binding partners

scientific article published on 13 September 2024

Synthesis of Enantiomerically Pure Ring-Substituted l-Pyridylalanines by Biocatalytic Hydroamination

scientific article published on 21 October 2016

Synthesis of N-linked glycopeptides on solid support and their evaluation as protease substrates

scientific article published in January 2005

Synthesis of a novel acceptor substrate for a mannosyl transferase

Synthesis of homogenous site-selectively glycosylated proteins

scientific article published on 24 December 2004

Synthesis of novel acceptor substrates for the dolichyl phosphate mannose synthase from yeast

scientific article published in April 2003

Synthesis of protected 3-aminopiperidine and 3-aminoazepane derivatives using enzyme cascades

scientific article published on 12 June 2020

The Time and Place for Nature in Drug Discovery

scientific article published on 28 November 2022

The characterisation of a galactokinase from Streptomyces coelicolor

scientific article published in January 2019

The chemoenzymatic synthesis of neoglycolipids and lipid-linked oligosaccharides using glycosyltransferases

scientific article published on 01 November 1994

The chemoenzymatic synthesis of the core trisaccharide of N-linked oligosaccharides using a recombinant beta-mannosyltransferase.

scientific article published in December 1997

The crystal structure of P450-TT heme-domain provides the first structural insights into the versatile class VII P450s

scholarly article by Michele Tavanti published in July 2018

The preparation of deoxy derivatives of mannose-1-phosphate and their substrate specificity towards recombinant GDP-mannose pyrophosphorylase from Salmonella enterica, group B

The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac

scientific article published on 18 January 2017

Three-Component Stereoselective Enzymatic Synthesis of Amino-Diols and Amino-Polyols

scientific article published on 24 October 2022

Two-Photon Microscopy to Spatially Resolve and Quantify Fluorophores in Single-Bead Chemistry

scientific article published on 01 May 2003

UDP-Glucose 4-Epimerase and β-1,4-Galactosyltransferase from the Oyster Magallana gigas as Valuable Biocatalysts for the Production of Galactosylated Products.

scientific article published on 29 May 2018

Understanding enzyme action on immobilised substrates

scientific article

Understanding protease catalysed solid phase peptide synthesis

scientific article published in April 2003

Using two photon microscopy to quantify enzymatic reaction rates on polymer beads

scientific article published in November 2003

Utility of Ion-Mobility Spectrometry for Deducing Branching of Multiply Charged Glycans and Glycopeptides in a High-Throughput Positive ion LC-FLR-IMS-MS Workflow

scientific article published on 09 November 2020

Whole-Cell Biocatalysts for Stereoselective C-H Amination Reactions

scientific article published on 21 December 2015

Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s

scientific article

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