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List of works by Gaia Spinetti

3D hydrogel environment rejuvenates aged pericytes for skeletal muscle tissue engineering

scientific article

A local proinflammatory signalling loop facilitates adverse age-associated arterial remodeling

scientific article

Adenovirus-mediated VEGF(165) gene transfer enhances wound healing by promoting angiogenesis in CD1 diabetic mice

scientific article published in October 2002

Analysis of the role of chemokines in angiogenesis.

scientific article

Bone marrow as a target and accomplice of vascular complications in diabetes

scientific article published on 15 December 2019

Close Encounters of the Third Kind

scholarly article

Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia

scientific article

Diabetes and vessel wall remodelling: from mechanistic insights to regenerative therapies.

scientific article

Diabetes mellitus induces bone marrow microangiopathy

scientific article

Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus

scientific article published on 30 July 2020

Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent

scientific article published on 26 April 2010

Enhancing Stem Cell Mobility: New Hope for Treatment of Cardiovascular Complications in Patients With Diabetes?

scientific article published in August 2015

Epigenetic Profile of Human Adventitial Progenitor Cells Correlates With Therapeutic Outcomes in a Mouse Model of Limb Ischemia

scientific article published on 08 January 2015

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

scientific article

Global remodeling of the vascular stem cell niche in bone marrow of diabetic patients: implication of the microRNA-155/FOXO3a signaling pathway

scientific article published on 18 December 2012

High-level expression of a recombinant active microbial transglutaminase in Escherichia coli

scientific article published on 15 September 2015

Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

scientific article published on 01 May 2021

Increased antioxidant defense mechanism in human adventitia-derived progenitor cells is associated with therapeutic benefit in ischemia

scientific article published in April 2014

Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells

scientific article

Laminar shear stress inhibits CXCR4 expression on endothelial cells: functional consequences for atherogenesis.

scientific article published on 10 February 2005

Matrix Metalloproteinase 2 Activation of Transforming Growth Factor-β1 (TGF-β1) and TGF-β1–Type II Receptor Signaling Within the Aged Arterial Wall

scientific article published on 11 May 2006

MicroRNA-15a and microRNA-16 impair human circulating proangiogenic cell functions and are increased in the proangiogenic cells and serum of patients with critical limb ischemia

scientific article published on 11 December 2012

Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction

scientific article published on 11 April 2015

Migratory activity of circulating mononuclear cells is associated with cardiovascular mortality in type 2 diabetic patients with critical limb ischemia.

scientific article published on 26 February 2014

Migratory activity of circulating progenitor cells and serum SDF-1α predict adverse events in patients with myocardial infarction

scientific article published on 12 June 2013

Multi-Omics Analysis of Diabetic Heart Disease in the db/db Model Reveals Potential Targets for Treatment by a Longevity-Associated Gene

scientific article published on 21 May 2020

Neurotrophin p75 receptor (p75NTR) promotes endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impaired neovascularization in ischemic limb muscles

scientific article published on 19 June 2008

Nitric oxide-donating statin improves multiple functions of circulating angiogenic cells.

scientific article

Overexpression of miR-210 and its significance in ischemic tissue damage.

scientific article published on 25 August 2017

Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension.

scientific article

Preclinical and clinical phase I studies of a new recombinant Filgrastim (BK0023) in comparison with Neupogen®

scientific article

Proinflammatory Profile Within the Grossly Normal Aged Human Aortic Wall

scientific article published on 23 April 2007

Rat aortic MCP-1 and its receptor CCR2 increase with age and alter vascular smooth muscle cell function

scientific journal article

Reactive oxygen species adversely impacts bone marrow microenvironment in diabetes

scientific article

Recombinant Filgrastim (BK0023) Pharmacodynamics and Pharmacokinetics After Single and Multiple Escalating Doses in an Equivalence Study in Healthy Men

scientific article published on 01 September 2015

Role for substance p-based nociceptive signaling in progenitor cell activation and angiogenesis during ischemia in mice and in human subjects

scientific article published on 5 March 2012

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion

scientific article

Role of kinin B2 receptor signaling in the recruitment of circulating progenitor cells with neovascularization potential

scientific article

Sensory neuropathy hampers nociception-mediated bone marrow stem cell release in mice and patients with diabetes.

scientific article published on 10 September 2015

Soluble ST2 is regulated by p75 neurotrophin receptor and predicts mortality in diabetic patients with critical limb ischemia

scientific article published on 11 October 2012

Targeting stem cell niches and trafficking for cardiovascular therapy ⬇️

scientific article published on October 20, 2010

Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.

scientific article published on 16 December 2010

Training monocytes by physical exercise: good practice for improving collateral artery development and postischemic outcomes.

scientific article published in August 2015

What's new in regenerative medicine: split up of the mesenchymal stem cell family promises new hope for cardiovascular repair.

scientific article published on 11 August 2012

microRNA-21/PDCD4 Proapoptotic Signaling From Circulating CD34+ Cells to Vascular Endothelial Cells: A Potential Contributor to Adverse Cardiovascular Outcomes in Patients With Critical Limb Ischemia

scientific article published on 01 May 2020

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