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List of works by Melania Manco

-Cell Function in Severely Obese Type 2 Diabetic Patients: Long-term effects of bariatric surgery

scientific article published on 01 April 2007

A new sensitive and accurate model to predict moderate to severe obstructive sleep apnea in patients with obesity

scientific article published on 01 August 2019

A new simple formula built on the American Academy of Pediatrics criteria for the screening of hypertension in overweight/obese children

scientific article published on 18 June 2019

Acoustic radiation force impulse (ARFI) imaging with Virtual Touch Tissue Quantification in liver disease associated with cystic fibrosis in children ⬇️

scientific article published on September 17, 2012

Additional maternal and nonmaternal factors contribute to microbiota shaping in newborns.

scientific article published on 27 September 2010

Albuminuria and insulin resistance in children with biopsy proven non-alcoholic fatty liver disease.

scientific article published on 26 February 2009

Arterial Stiffness, Thickness and Association to Suitable Novel Markers of Risk at the Origin of Cardiovascular Disease in Obese Children

scientific article published on 12 July 2017

Association between Maternal and Foetal Erythrocyte Fatty Acid Profiles and Birth Weight

scientific article published on 23 March 2018

Association between type two diabetes and non-alcoholic fatty liver disease in youth.

scientific article published on January 2009

Association of Bright Liver With the PNPLA3 I148M Gene Variant in 1-Year-Old Toddlers

scientific article published on 01 June 2019

Back to past leeches: repeated phlebotomies and cardiovascular risk ⬇️

scientific article published on May 30, 2012

Beyond the morphology of the glucose curve following an oral glucose tolerance test in obese youth

scientific article published on 18 October 2011

Biliopancreatic diversion as a novel approach to the HAIR-AN syndrome

scientific article published in February 2005

Biomarkers of Alzheimer disease, insulin resistance, and obesity in childhood.

scientific article

Bloodletting ameliorates insulin sensitivity and secretion in parallel to reducing liver iron in carriers of HFE gene mutations.

scientific article published on 24 October 2007

Case management in children affected by non-alcoholic fatty liver disease

scientific article published on 01 May 2007

Changes in fat mass influence SREBP-1c and UCP-2 gene expression in formerly obese subjects

scientific article published in March 2005

Childhood obesity classification systems and cardiometabolic risk factors: a comparison of the Italian, World Health Organization and International Obesity Task Force references

scientific article published on 04 February 2017

Correction to: One hour post-load plasma glucose and 3 year risk of worsening fasting and 2 hour glucose tolerance in the RISC cohort

scientific article published on 01 May 2019

Correlation of serum TNF-alpha levels and histologic liver injury scores in pediatric nonalcoholic fatty liver disease

scientific article published on 01 June 2007

Data-as-a-Service Platform for Delivering Healthy Lifestyle and Preventive Medicine: Concept and Structure of the DAPHNE Project ⬇️

scientific article

Decreased muscle acetyl-coenzyme A carboxylase 2 mRNA and insulin resistance in formerly obese subjects

scientific article

Decreased uncoupling protein expression and intramyocytic triglyceride depletion in formerly obese subjects

scientific article published in May 2003

Determination of plasma pipecolic acid by an easy and rapid liquid chromatography-tandem mass spectrometry method

scientific article published on 15 November 2014

Diagnosis, treatment and prevention of pediatric obesity: consensus position statement of the Italian Society for Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics

scientific article published on 31 July 2018

Different fat distribution as marker of disease in nonalcholic fatty liver disease

scientific article published in October 2007

Differential effect of weight loss on insulin resistance in surgically treated obese patients.

scientific article published in January 2005

Docosahexaenoic acid supplementation during pregnancy: a potential tool to prevent membrane rupture and preterm labor

scientific article

Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetic subjects.

scientific article published on 20 June 2006

Does the hormone of eternal youth protect against nonalcoholic steatohepatitis?

scientific article

Early interplay of intra-hepatic iron and insulin resistance in children with non-alcoholic fatty liver disease

scientific article

Early-life gut microbiota under physiological and pathological conditions: the central role of combined meta-omics-based approaches.

scientific article

Effect of massive weight loss on inflammatory adipocytokines and the innate immune system in morbidly obese women.

scientific article published on 14 November 2006

Effects of bilio-pancreatic diversion on diabetic complications: a 10-year follow-up ⬇️

scientific article

Effects of dietary fatty acids on insulin sensitivity and secretion

scientific article published in November 2004

Effects of iron overload on chronic metabolic diseases.

scientific article published on 30 December 2013

Effects of weight loss and calorie restriction on carbohydrate metabolism

scientific article

Elevated blood pressure, cardiometabolic risk and target organ damage in youth with overweight and obesity

scientific article published on 01 June 2020

Endotoxin and plasminogen activator inhibitor-1 serum levels associated with nonalcoholic steatohepatitis in children

scientific article published in June 2010

Endotoxin as a missed link among all the metabolic abnormalities in the metabolic syndrome

scientific article published on 05 April 2009

Energy Balance-Related Behaviors, Perinatal, Sociodemographic, and Parental Risk Factors Associated with Obesity in Italian Preschoolers

scientific article

Epicardial fat, abdominal adiposity and insulin resistance in obese pre-pubertal and early pubertal children.

scientific article published on 3 December 2012

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

scientific article published in September 2005

First-phase insulin secretion restoration and differential response to glucose load depending on the route of administration in type 2 diabetic subjects after bariatric surgery.

scientific article

Fructose at the center of necroinflammation and fibrosis in nonalcoholic steatohepatitis1

scientific article published on 29 July 2010

Genetics of Pediatric Obesity ⬇️

scientific article published on 04 June 2012

Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis

scientific article published on 15 February 2011

Glucose Disposal in Morbidly Obese Patients in the Early Post-operative Period ⬇️

scientific article published on December 1, 2001

Glucose Measurements at Various Time Points During the OGTT and Their Role in Capturing Glucose Response Patterns

scientific article published on 28 January 2019

Growth hormone and ghrelin secretion in severely obese women before and after bariatric surgery

scientific article published in August 2007

Gut Microbiota and Developmental Programming of the Brain: From Evidence in Behavioral Endophenotypes to Novel Perspective in Obesity ⬇️

scientific article published on August 15, 2012

Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk

scientific article published on 30 June 2010

How much we worry for liver fat in children?

scientific article published on 01 September 2007

How to consider low serum vitamin D as a risk factor for insulin resistance?

scientific article published on 01 November 2004

Hypocalcemia complicating near-total thyroidectomy in patients with coexisting lipid malabsorption due to biliopancreatic diversion

scientific article published in November 2004

Impact of the 2017 Blood Pressure Guidelines by the American Academy of Pediatrics in overweight/obese youth

scientific article published on 01 April 2019

Influence of Maternal Obesity and Gestational Weight Gain on Maternal and Foetal Lipid Profile

scientific article published on 15 June 2016

Influence of maternal obesity on insulin sensitivity and secretion in offspring

scientific article published on 5 June 2008

Inside out the Ragbag of Glucose Intolerance in Obese Adolescents

scientific article published on 7 April 2017

Insulin Resistance and NAFLD: A Dangerous Liaison beyond the Genetics

scientific article published on 14 August 2017

Insulin Resistance, Microbiota, and Fat Distribution Changes by a New Model of Vertical Sleeve Gastrectomy in Obese Rats.

scientific article

Insulin dynamics in young women with polycystic ovary syndrome and normal glucose tolerance across categories of body mass index

scientific article

Insulin dynamics of breast- or formula-fed overweight and obese children

scientific article published on 01 February 2011

Insulin resistance and exercise capacity in male children and adolescents with non-alcholic fatty liver disease

scientific article published on 7 October 2008

Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion

scientific article

Insulin sensitivity from preschool to school age in patients with severe obesity

scientific article

Intensive treatment and dietary fats in adolescents with nonalcoholic fatty liver disease

scientific article published on 01 February 2008

Intima-media thickness and liver histology in obese children and adolescents with non-alcoholic fatty liver disease

scientific article published on 17 October 2009

Intrauterine growth retardation, insulin resistance, and nonalcoholic fatty liver disease in children

scientific article published on 29 May 2007

Iron influences on the Gut-Brain axis and development of type 2 diabetes

scientific article published on 8 September 2017

Leptin pulsatility in formerly obese women

scientific article published on 13 June 2005

Leptin, free leptin index, insulin resistance and liver fibrosis in children with non-alcoholic fatty liver disease.

scientific article published in November 2006

Lifestyle advice in non-alcoholic fatty liver disease

scientific article published on 01 April 2007

Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease: a randomized, controlled trial

scientific article published in July 2008

Liraglutide Treatment Ameliorates Neurotoxicity Induced by Stable Silencing of Pin1

scientific article published on 12 October 2019

Low 25-hydroxyvitamin D does not affect insulin sensitivity in obesity after bariatric surgery

scientific article

Low levels of 25-hydroxyvitamin D(3) in children with biopsy-proven nonalcoholic fatty liver disease.

scientific article published in June 2010

Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab

scientific article published in April 2004

Lowering of circulating free-fatty acids levels and reduced expression of leptin in white adipose tissue in postobesity status

scientific article published in May 2002

Massive weight loss decreases corticosteroid-binding globulin levels and increases free cortisol in healthy obese patients: an adaptive phenomenon?

scientific article published in June 2007

Maternal Intake of n-3 Polyunsaturated Fatty Acids During Pregnancy Is Associated With Differential Methylation Profiles in Cord Blood White Cells

scientific article published on 25 October 2019

Measurement of advanced glycation end products may change NASH management

scientific article published on 01 September 2007

Mechanisms Linking Glucose Homeostasis and Iron Metabolism Toward the Onset and Progression of Type 2 Diabetes.

scientific article

Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery

scientific article published in July 2006

Menopause, insulin resistance, and risk factors for cardiovascular disease

scientific article published in September 2006

Metabolic Syndrome in Childhood from Impaired Carbohydrate Metabolism to Nonalcoholic Fatty Liver Disease ⬇️

scientific article published on October 1, 2011

Metformin use in children with nonalcoholic fatty liver disease: an open-label, 24-month, observational pilot study.

scientific article published on June 2008

NEFA-glucose comodulation model of beta-cell insulin secretion in 24-h multiple-meal test.

scientific article

Natural antioxidant ice cream acutely reduces oxidative stress and improves vascular function and physical performance in healthy individuals

scientific article

New Perspectives in Glioblastoma: Nanoparticles-based Approaches.

scientific article published on 13 August 2016

New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery

scientific article published on 21 November 2019

Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: Pathogenetic role of genetic background and intrauterine environment ⬇️

scientific article published on February 28, 2011

Nonalcoholic Fatty Liver Is Not Associated with the Relationship between Insulin Secretion and Insulin Sensitivity in Obese Children: Matched Case-Control Study.

scientific article published on 19 August 2016

Nonalcoholic fatty liver disease in children

scientific article published on 01 December 2008

Noninvasive assessment of cystic fibrosis-associated liver disease with acoustic radiation force impulse imaging

scientific article published on 01 May 2011

NutricheQ Questionnaire assesses the risk of dietary imbalances in toddlers from 1 through 3 years of age.

scientific article published on 18 December 2015

One hour post-load plasma glucose and 3 year risk of worsening fasting and 2 hour glucose tolerance in the RISC cohort.

scientific article

One-hour plasma glucose identifies insulin resistance and beta-cell dysfunction in individuals with normal glucose tolerance: cross-sectional data from the Relationship between Insulin Sensitivity and Cardiovascular Risk (RISC) study ⬇️

scientific article

Opinion on the re-evaluation of ascorbyl palmitate (E 304i) as a food additive in foods for infants below 16 weeks of age and the follow-up of its re-evaluation as a food additive for uses in foods for all population groups

scientific article published on 30 June 2020

Opinion on the re-evaluation of lecithins (E 322) as a food additive in foods for infants below 16 weeks of age and follow-up of its re-evaluation as food additive for uses in foods for all population groups

scientific article published on 10 November 2020

Opinion on the re-evaluation of starch sodium octenyl succinate (E 1450) as a food additive in foods for infants below 16 weeks of age and the follow-up of its re-evaluation as a food additive for uses in foods for all population groups

scientific article published on 13 August 2020

Oral glucose effectiveness and metabolic risk in obese children and adolescents

scientific article published on 13 March 2019

Origin of cardiovascular risk in overweight preschool children: a cohort study of cardiometabolic risk factors at the onset of obesity.

scientific article published in October 2014

Pathophysiological Characteristics Underlying Different Glucose Response Curves: A Latent Class Trajectory Analysis From the Prospective EGIR-RISC Study

scientific article published on 31 May 2018

Pediatric nonalcoholic fatty liver disease in 2009.

scientific article published on October 2009

Percentiles of serum uric acid and cardiometabolic abnormalities in obese Italian children and adolescents

scientific article published on 03 January 2017

Petition to replace current OGTT criteria for diagnosing prediabetes with the 1-hour post-load plasma glucose ≥ 155 mg/dl (8.6 mmol/l)

scientific article published on 28 September 2018

Pilot study on the use of acoustic radiation force impulse imaging in the staging of cystic fibrosis associated liver disease

scientific article published on 24 April 2012

Pin1 Modulation in Physiological Status and Neurodegeneration. Any Contribution to the Pathogenesis of Type 3 Diabetes?

scholarly article by Marzia Bianchi published in August 2018

Population-based screening programs for nonalcoholic fatty liver disease in youth and clues to prevention

scientific article published on 01 March 2014

Preclinical signs of liver and cardiac damage in youth with metabolically healthy obese phenotype

Predictors of weight loss and reversal of comorbidities in malabsorptive bariatric surgery

scientific article published in June 2005

Prolactin and insulin ultradian secretion and adipose tissue lipoprotein lipase expression in severely obese women after bariatric surgery

scientific article published on 5 June 2008

Publisher Correction: New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery

scientific article published on 12 February 2020

Re-evaluation of polyvinylpyrrolidone (E 1201) and polyvinylpolypyrrolidone (E 1202) as food additives and extension of use of polyvinylpyrrolidone (E 1201)

scientific article published on 10 August 2020

Re-evaluation of sodium aluminium silicate (E 554) and potassium aluminium silicate (E 555) as food additives

scientific article published on 10 June 2020

Recently discovered adipokines and cardio-metabolic comorbidities in childhood obesity

scientific article

Reduced PDK4 expression associates with increased insulin sensitivity in postobese patients

scientific article (publication date: February 2003)

Reduced cardio-respiratory fitness in obesity with and without nonalcoholic fatty liver disease

scientific article published on 01 August 2008

Reduced expression of uncoupling proteins-2 and -3 in adipose tissue in post-obese patients submitted to biliopancreatic diversion

scientific article published in May 2003

Reference ranges of HOMA-IR in normal-weight and obese young Caucasians

scientific article published on 13 June 2015

Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease

scientific article published in February 2011

Restoration of adiponectin pulsatility in severely obese subjects after weight loss

scientific article published in April 2004

Retinol-binding protein 4: a promising circulating marker of liver damage in pediatric nonalcoholic fatty liver disease.

scientific article published on 13 January 2009

Review of Methods for Detecting Glycemic Disorders

scientific article published on 01 June 2020

Risk of severe liver disease in NAFLD with normal ALT levels: a pediatric report.

scientific article

Role of Fatty Liver Disease in Childhood Obesity

scientific article published in 2011

Safety of a proposed amendment of the specifications for steviol glycosides (E 960) as a food additive: to expand the list of steviol glycosides to all those identified in the leaves of Stevia Rebaudiana Bertoni

scientific article published on 29 April 2020

Scientific Opinion on Flavouring Group Evaluation 69, Revision 1 (FGE.69Rev1): consideration of aromatic substituted secondary alcohols, ketones and related esters evaluated by JECFA (57th meeting), structurally related to aromatic ketones from chem

scientific article published on 05 November 2020

Scientific Opinion on Flavouring Group Evaluation 91, Revision 3 (FGE.91Rev3): consideration of aliphatic, aromatic and α,β-unsaturated sulfides and thiols evaluated by JECFA (53rd, 61st, 68th and 76th meetings), structurally related to substances i

scientific article published on 10 June 2020

Severe obesity and cardiometabolic risk in children: comparison from two international classification systems

scientific article

Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease

scientific article published in June 2010

Sexual dimorphism of body composition and insulin sensitivity across pubertal development in obese Caucasian subjects

scientific article published on 16 February 2009

Shape of the OGTT glucose curve and risk of impaired glucose metabolism in the EGIR-RISC cohort

scientific article published on 14 February 2017

Study of circulating prohepcidin in association with insulin sensitivity and changing iron stores

scientific article

Surfactant protein d, a marker of lung innate immunity, is positively associated with insulin sensitivity

scientific article

Systematic review of metformin use in obese nondiabetic children and adolescents

scientific article published on 26 July 2013

The American Academy of Pediatrics hypertension guidelines identify obese youth at high cardiovascular risk among individuals non-hypertensive by the European Society of Hypertension guidelines

scientific article published on 06 August 2019

The Benefit of Sleeve Gastrectomy in Obese Adolescents on Nonalcoholic Steatohepatitis and Hepatic Fibrosis

scientific article published on 30 September 2016

The Bones of Children With Obesity

scientific article published on 24 April 2020

The Wide Spectrum of Hepatic Iron Overload Δ ⬇️

scientific article published on March 1, 2011

The decrease of serum levels of human neutrophil alpha-defensins parallels with the surgery-induced amelioration of NASH in obesity.

scientific article published in December 2010

The ingestion of saturated fatty acid triacylglycerols acutely affects insulin secretion and insulin sensitivity in human subjects.

scientific article published in December 2004

Therapeutic strategies for pediatric non-alcoholic fatty liver disease: a challenge for health care providers

scientific article published on May 2007

Thyroid function tests in obese prepubertal children: correlations with insulin sensitivity and body fat distribution

scientific article published on 26 July 2012

Triglycerides-to-HDL cholesterol ratio as screening tool for impaired glucose tolerance in obese children and adolescents

scientific article published on 21 December 2015

Twenty-four hour energy expenditure and skeletal muscle gene expression changes after bariatric surgery.

scientific article

Ultradian ghrelin pulsatility is disrupted in morbidly obese subjects after weight loss induced by malabsorptive bariatric surgery

scientific article published in May 2006

Uric acid, impaired fasting glucose and impaired glucose tolerance in youth with overweight and obesity

scientific article published on 13 October 2020

Utility of magnetic resonance imaging in the evaluation of hepatic fat content.

scientific article published in July 2009

Zinc-α2 -glycoprotein is associated with insulin resistance in children

scientific article published on 29 November 2014

[Obesity and cardiovascular risk in children]

scientific article published on 01 December 2014

beta-cell function in morbidly obese subjects during free living: long-term effects of weight loss

scientific article published in August 2005

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