List of works - Riccardo Brambilla

A simple role for BDNF in learning and memory?

scientific article

Bombesin stimulates a high affinity GTPase activity in membranes of Swiss 3T3 fibroblasts

scientific article published on May 1991

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments.

scientific article published on 27 November 2008

CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

scientific article published on October 1999

Cerebellar neurons and glial cells are transducible by lentiviral vectors without decrease of cerebellar functions.

scientific article published in January 2006

Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor Control

scientific article published on 4 November 2015

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

scientific article

Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia.

scientific article published on 12 April 2014

Differential allelic expression of SOS1 and hyperexpression of the activating SOS1 c.755C variant in a Noonan syndrome family

scientific article

Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia

scientific article published on 24 April 2015

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

scientific article

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

scientific article published on January 2006

Effect of the different dimeric forms of the platelet-derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts

scientific article published on September 1989

Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.

scientific article

Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

scientific article

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.

scientific article

Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors.

scientific article

Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity

scientific article

Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse

scientific article published on 9 September 2009

Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability

scientific journal article

Is the Ras-MAPK signalling pathway necessary for long-term memory formation?

scientific article

Kinetics of tyrosine phosphorylation and internalization of human EGF receptors overexpressed in NIH 3T3 fibroblasts

scientific article published on December 1990

Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory

scientific article

Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity

scientific article published on 11 January 2006

Mice Lacking Ras-GRF1 Show Contextual Fear Conditioning but not Spatial Memory Impairments: Convergent Evidence from Two Independently Generated Mouse Mutant Lines

scientific article published on 6 December 2011

Midlatency auditory event-related potentials in mice: comparison to midlatency auditory ERPs in humans

scientific article published in September 2004

Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum.

scientific article published on July 2013

Multipotential neural precursors transplanted into the metachromatic leukodystrophy brain fail to generate oligodendrocytes but contribute to limit brain dysfunction

scientific article published on 30 July 2008

Neurobiology of Learning and Memory. Editorial

scientific article published on 5 August 2015

Neuronal signaling and behavior

scientific article published on 2 November 2012

Nociceptin/Orphanin FQ Receptor Agonists Attenuate L-DOPA-Induced Dyskinesias

scientific article published on 01 November 2012

Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2

scientific article published on 4 October 2023

Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy.

scientific article published in March 2006

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

scientific article published on 21 July 2015

Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) controls activation of extracellular signal-regulated kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine.

scientific article published on 15 May 2009

Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

scientific article published on 13 February 2015

Role of nucleus accumbens μ opioid receptors in the effects of morphine on ERK1/2 phosphorylation.

scientific article

Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy.

scientific article published in September 2007

Severe Intellectual Disability and Enhanced Gamma-Aminobutyric Acidergic Synaptogenesis in a Novel Model of Rare RASopathies.

scientific article

Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors.

scientific article published on January 1996

Synaptic GluN2B/CaMKII-α Signaling Induces Synapto-Nuclear Transport of ERK and Jacob

scientific article published on 10 August 2016

Targeting Ras/ERK signaling in the striatum: will it help? ⬇️

scientific article published on April 1, 2003

The N-terminal domain of ERK1 accounts for the functional differences with ERK2

scientific article

The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling

scientific article published on July 1997

Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation.

scientific article

Understanding cognitive deficits in Parkinson's disease: lessons from preclinical animal models

scientific article

Viral vector approaches to modify gene expression in the brain.

scientific article published on 20 August 2009

List of works by Riccardo Brambilla

A simple role for BDNF in learning and memory?

Bombesin stimulates a high affinity GTPase activity in membranes of Swiss 3T3 fibroblasts

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments.

CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

Cerebellar neurons and glial cells are transducible by lentiviral vectors without decrease of cerebellar functions.

Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor Control

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia.

Differential allelic expression of SOS1 and hyperexpression of the activating SOS1 c.755C variant in a Noonan syndrome family

Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

Effect of the different dimeric forms of the platelet-derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts

Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.

Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.

Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors.

Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity

Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse

Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability

Is the Ras-MAPK signalling pathway necessary for long-term memory formation?

Kinetics of tyrosine phosphorylation and internalization of human EGF receptors overexpressed in NIH 3T3 fibroblasts

Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory

Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity

Mice Lacking Ras-GRF1 Show Contextual Fear Conditioning but not Spatial Memory Impairments: Convergent Evidence from Two Independently Generated Mouse Mutant Lines

Midlatency auditory event-related potentials in mice: comparison to midlatency auditory ERPs in humans

Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum.

Multipotential neural precursors transplanted into the metachromatic leukodystrophy brain fail to generate oligodendrocytes but contribute to limit brain dysfunction

Neurobiology of Learning and Memory. Editorial

Neuronal signaling and behavior

Nociceptin/Orphanin FQ Receptor Agonists Attenuate L-DOPA-Induced Dyskinesias

Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2

Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy.

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) controls activation of extracellular signal-regulated kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine.

Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

Role of nucleus accumbens μ opioid receptors in the effects of morphine on ERK1/2 phosphorylation.

Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy.

Severe Intellectual Disability and Enhanced Gamma-Aminobutyric Acidergic Synaptogenesis in a Novel Model of Rare RASopathies.

Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors.

Synaptic GluN2B/CaMKII-α Signaling Induces Synapto-Nuclear Transport of ERK and Jacob

Targeting Ras/ERK signaling in the striatum: will it help? ⬇️

The N-terminal domain of ERK1 accounts for the functional differences with ERK2

The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling

Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation.

Understanding cognitive deficits in Parkinson's disease: lessons from preclinical animal models

Viral vector approaches to modify gene expression in the brain.