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List of works by Hubert Hackl

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

3D-cultivation of NSCLC cell lines induce gene expression alterations of key cancer-associated pathways and mimic in-vivo conditions

scientific article published on 6 November 2017

A gene expression profile associated with relapse of cytogenetically normal acute myeloid leukemia is enriched for leukemia stem cell genes

scientific article published on 18 August 2014

A modified scoring of the NCCN-IPI is more accurate in the elderly and is improved by albumin and β2 -microglobulin

scientific article published on 19 September 2014

Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice

scientific article

All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia

scientific article published on 10 December 2019

Amphotericin B Resistance in Aspergillus terreus Is Overpowered by Coapplication of Pro-oxidants.

scientific article published on 9 June 2015

Analysis of DNA microarray data

scientific article

ArrayNorm: comprehensive normalization and analysis of microarray data

scientific article

Arxes: retrotransposed genes required for adipogenesis

scientific journal article

Association between antibiotics use and outcome in patients with NSCLC treated with immunotherapeutics

scientific article published on 01 April 2019

Baseline Absolute Lymphocyte Count and ECOG Performance Score Are Associated with Survival in Advanced Non-Small Cell Lung Cancer Undergoing PD-1/PD-L1 Blockade

scientific article published on 10 July 2019

Bioinformatics for cancer immunology and immunotherapy

scientific article

CGRP Signaling via CALCRL Increases Chemotherapy Resistance and Stem Cell Properties in Acute Myeloid Leukemia

scientific article published on 20 November 2019

Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications

scientific article

Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy.

scientific article

Clinical Impact of RANK Signalling in Ovarian Cancer

scientific article published on 08 June 2019

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

scientific article published on 6 June 2016

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

scientific article

Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis

scientific article

Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses

scientific article published on 12 October 2021

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

scientific article published on 29 June 2015

Computational genomics tools for dissecting tumour-immune cell interactions

scientific article

Consequences of Perioperative Serotonin Reuptake Inhibitor Treatment during Hepatic Surgery

scientific article published on 20 October 2020

Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions

scientific article

DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer.

scientific article

Differential gene expression in Aspergillus fumigatus induced by human platelets in vitro.

scientific article published on 17 January 2015

Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen

scientific article published in February 2012

Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice

scientific article

Differentiation Between Vascularized Composite Allograft Acute Skin Rejection and Delayed Type Hypersensitivity Reactions Based on Cytokine Analysis

Differentiation between acute skin rejection in allotransplantation and T-cell mediated skin inflammation based on gene expression analysis

scientific article published on 12 February 2015

Dynamics of Bile Acid Profiles, GLP-1, and FGF19 After Laparoscopic Gastric Banding

scientific article published on 07 June 2017

EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells

scientific article

EVI1 promotes tumor growth via transcriptional repression of MS4A3.

scientific article published on 21 March 2015

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation

scientific article published on 25 May 2013

Effects of oxidized phospholipids on gene expression in RAW 264.7 macrophages: a microarray study.

scientific article

Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer.

scientific article

Enhanced Expression of Genes Related to Xenobiotic Metabolism in the Skin of Patients with Atopic Dermatitis but Not with Ichthyosis Vulgaris

scientific article published on 9 September 2017

Fetal HDL/apoE: a novel regulator of gene expression in human placental endothelial cells

article

Formation of lipid bodies and changes in fatty acid composition upon pre-akinete formation in Arctic and Antarctic Zygnema (Zygnematophyceae, Streptophyta) strains

scientific article published on 10 May 2016

GOLD.db: genomics of lipid-associated disorders database

scientific article

GPViz: dynamic visualization of genomic regions and variants affecting protein domains

scientific article

Gestational diabetes alters microRNA signatures in human feto-placental endothelial cells depending on fetal sex

scientific article published on 21 November 2018

Grape-seed derived procyanidins interfere with adipogenesis of 3T3-L1 cells at the onset of differentiation

scientific article published on August 2005

High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer

scientific article

Hospitalizations and Clinical Outcome in Metastatic Colorectal Cancer During Regorafenib or TAS-102 Therapy

scientific article published on 30 September 2020

Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro.

scientific article

Identification of New Targets Using Expression Profiles

Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome

scientific article published on 20 February 2017

Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells.

scientific article

Immunomodulation with pomalidomide at early lymphocyte recovery after induction chemotherapy in newly diagnosed AML and high-risk MDS

scientific article published on 03 January 2020

Impact of antibiotic treatment on immune-checkpoint blockade efficacy in advanced non-squamous non-small cell lung cancer

scientific article published on 27 March 2018

Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes

scientific article

Influence of body mass index on survival in indolent and mantle cell lymphomas: analysis of the StiL NHL1 trial

scientific article

Information technology solutions for integration of biomolecular and clinical data in the identification of new cancer biomarkers and targets for therapy

scientific article

Insights from computational modeling in inflammation and acute rejection in limb transplantation

scientific article

Insights into global mechanisms and disease by gene expression profiling

scientific article published on January 2011

Integrating Biomolecular and Clinical Data for Cancer Research: Concepts and Challenges

Investigating epigenetic effects of activation-induced deaminase in chronic lymphocytic leukemia

scientific article published in PLoS ONE

Java editor for biological pathways

scientific article

KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients

scientific article published on 8 November 2016

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations.

scientific article

Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.

scientific article

Low Expression of miR-20a-5p Predicts Benefit to Bevacizumab in Metastatic Breast Cancer Patients Treated within the TANIA Phase III Trial

scientific article published on 01 June 2020

MARS: microarray analysis, retrieval, and storage system

scientific article

MIO: microRNA target analysis system for immuno-oncology

scientific article published in 2022

Mathematical models for translational and clinical oncology

scientific article

MicroRNAs and their role for T stage determination and lymph node metastasis in early colon carcinoma.

scientific article

Microbial Colonization in Adulthood Shapes the Intestinal Macrophage Compartment

scientific article published on 01 September 2019

Modeling therapy resistance via the EGFR signaling pathway

scientific article published on 20 March 2019

Molecular and genetic alterations associated with therapy resistance and relapse of acute myeloid leukemia

scientific article published on 20 February 2017

Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

scientific article published on 24 May 2019

Molecular processes during fat cell development revealed by gene expression profiling and functional annotation

scientific article

Next-generation computational tools for interrogating cancer immunity

scientific article published on 12 September 2019

Novel insights into adipogenesis from omics data

scientific article

Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue

scientific article

Outgrowth, proliferation, viability, angiogenesis and phenotype of primary human endothelial cells in different purchasable endothelial culture media: feed wisely

scientific article published on 21 September 2019

Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.

scientific article

Overexpression of primary microRNA 221/222 in acute myeloid leukemia

scientific article

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.

scientific article published in January 2017

PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways

scientific article

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.

scientific article

Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.

scientific article published on 15 June 2010

Reduced mRNA expression levels of NFE2L2 are associated with poor outcome in breast cancer patients.

scientific article

Regorafenib Is Associated With Increased Skeletal Muscle Loss Compared to TAS-102 in Metastatic Colorectal Cancer

scientific article published on 11 April 2019

SOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness

scientific article published on 24 June 2019

Sex matching does not impact the outcome after simultaneous pancreas-kidney transplantation

scientific article published on 04 October 2019

Sidedness and TP53 mutations impact OS in anti-EGFR but not anti-VEGF treated mCRC - an analysis of the KRAS registry of the AGMT (Arbeitsgemeinschaft Medikamentöse Tumortherapie).

scientific article published on 3 January 2018

Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy

scientific article published on 02 November 2018

TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation

scientific article

TNFα signalling predicts poor prognosis of patients with endometrial cancer

scientific article published on 06 April 2020

Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.

scientific article published on 2 January 2018

Tetracycline regulator expression alters the transcriptional program of mammalian cells

scientific article

The Effects of Endurance Exercise and Diet on Atherosclerosis in Young and Aged ApoE –/– and Wild-Type Mice

scientific article published on 30 August 2018

The Impact of Skin Type and Area on Skin Rejection in Limb Transplantation

The colorectal cancer immune paradox revisited.

scientific article published on 27 August 2015

The human placental sexome differs between trophoblast epithelium and villous vessel endothelium

scientific article

The miR-34 family and its clinical significance in ovarian cancer

scientific article published on 13 January 2020

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid

scientific article published on January 2014

Toll-like receptor 3 mediates ischaemia/reperfusion injury after cardiac transplantation

scientific article published on 10 February 2020

Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation

scientific article

Truncated isoform Vav3.1 is highly expressed in ovarian cancer stem cells and clinically relevant in predicting prognosis and platinum-response

scientific article

Von Willebrand factor facilitates MELD-independent risk stratification on the waiting list for liver transplantation

scientific article published on 27 November 2019

miR-16-5p Is a Stably-Expressed Housekeeping MicroRNA in Breast Cancer Tissues from Primary Tumors and from Metastatic Sites

scientific article published on 26 January 2016

miR-19a-3p containing exosomes improve function of ischaemic myocardium upon shock wave therapy

scientific article published on 13 August 2019

microRNAs in acute myeloid leukemia: expression patterns, correlations with genetic and clinical parameters, and prognostic significance

scientific article published on March 2010

α/β-hydrolase domain containing protein 15 (ABHD15)--an adipogenic protein protecting from apoptosis.

scientific article

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