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List of works by Glenn W Kaatz

2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction

scientific article published on 17 August 2018

A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition

scientific article

A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus

scientific article published on 16 September 2013

A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus

scientific article

Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model

scientific article published on August 2003

Alternative mutational pathways to intermediate resistance to vancomycin in methicillin-resistant Staphylococcus aureus

scientific article published on 28 March 2013

Analyses of multidrug efflux pump-like proteins encoded on the Staphylococcus aureus chromosome.

scientific article published on 17 November 2014

Antibacterial Sesquiterpenoid Derivatives from Ferula ferulaeoides ⬇️

scientific article published on May 13, 2013

Antibacterial and resistance modifying activity of Rosmarinus officinalis

scientific article published in December 2004

Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana

scientific article published on 15 November 2006

Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline.

scientific article

Antimicrobial susceptibility and staphylococcal chromosomal cassette mec type in community- and hospital-associated methicillin-resistant Staphylococcus aureus

scientific article published on 01 January 2007

Bacterial efflux pump inhibition.

scientific article

Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus

scientific article published in December 2004

Characteristics of patients with healthcare-associated infection due to SCCmec type IV methicillin-resistant Staphylococcus aureus.

scientific article

Characterizing Vancomycin-Resistant Enterococcus Strains with Various Mechanisms of Daptomycin Resistance Developed in an In Vitro Pharmacokinetic/Pharmacodynamic Model ⬇️

scientific article published on July 25, 2011

Clinical isolates of Staphylococcus aureus from 1987 and 1989 demonstrating heterogeneous resistance to vancomycin and teicoplanin

scientific article published in February 2005

Clonal relatedness is a predictor of spontaneous multidrug efflux pump gene overexpression in Staphylococcus aureus

scientific article published on 10 December 2014

Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agents

scientific article published on 14 February 2007

Correction to From 6-Aminoquinolone Antibacterials to 6-Amino-7-thiopyranopyridinylquinolone Ethyl Esters as Inhibitors ofStaphylococcus aureusMultidrug Efflux Pumps

scientific article published on 10 March 2011

Correlation of vancomycin and daptomycin susceptibility in Staphylococcus aureus in reference to accessory gene regulator (agr) polymorphism and function

scientific article published on 13 April 2007

Discovery of Novel Inhibitors of the NorA Multidrug Transporter ofStaphylococcus aureus

Efavirenz-Associated Urinary Matrix Stone-A Rare Presentation

scientific article

Effect of promoter region mutations and mgrA overexpression on transcription of norA, which encodes a Staphylococcus aureus multidrug efflux transporter

scientific article

Effect of substrate exposure and other growth condition manipulations on norA expression

scientific article

Efflux-related resistance to norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus

scientific article

Ethidium Bromide MIC Screening for Enhanced Efflux Pump Gene Expression or Efflux Activity in Staphylococcus aureus ⬇️

scientific article published on September 20, 2010

Evaluation of Daptomycin Non-Susceptible Staphylococcus aureus for Stability, Population Profiles, mprF Mutations, and Daptomycin Activity

scientific article

Evaluation of ceftaroline activity against heteroresistant vancomycin-intermediate Staphylococcus aureus and vancomycin-intermediate methicillin-resistant S. aureus strains in an in vitro pharmacokinetic/pharmacodynamic model: exploring the "seesaw

scientific article published on 01 April 2013

Evaluation of dalbavancin, tigecycline, minocycline, tetracycline, teicoplanin and vancomycin against community-associated and multidrug-resistant hospital-associated meticillin-resistant Staphylococcus aureus

scientific article published on 8 November 2009

Evaluation of daptomycin treatment of Staphylococcus aureus bacterial endocarditis: an in vitro and in vivo simulation using historical and current dosing strategies

scientific article published on 31 May 2007

Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of theS. aureusNorA Efflux Pump

scientific article published on 03 August 2011

Expression of multidrug resistance efflux pump genes in clinical and environmental isolates of Staphylococcus aureus

scientific article published on 04 July 2012

Fluoroquinolone resistance in Streptococcus pneumoniae: area under the concentration-time curve/MIC ratio and resistance development with gatifloxacin, gemifloxacin, levofloxacin, and moxifloxacin

scientific article

From 6-aminoquinolone antibacterials to 6-amino-7-thiopyranopyridinylquinolone ethyl esters as inhibitors of Staphylococcus aureus multidrug efflux pumps

scientific article published in June 2010

From phenothiazine to 3-phenyl-1,4-benzothiazine derivatives as inhibitors of the Staphylococcus aureus NorA multidrug efflux pump

scientific article published on 25 June 2008

Functional Consequences of Substitution Mutations in MepR, a Repressor of the Staphylococcus aureus mepA Multidrug Efflux Pump Gene ⬇️

scientific article published on June 7, 2013

Goldenseal (Hydrastis canadensisL.) Extracts Synergistically Enhance the Antibacterial Activity of Berberine via Efflux Pump Inhibition ⬇️

scientific article published on December 14, 2010

Identification and characterization of a novel efflux-related multidrug resistance phenotype in Staphylococcus aureus

scientific article published in December 2002

Impact of inoculum size and heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) on vancomycin activity and emergence of VISA in an in vitro pharmacodynamic model

scientific article published on 17 November 2008

Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development.

scientific article published on 15 December 2016

In silico genetic correlations of multidrug efflux pump gene expression in Staphylococcus aureus.

scientific article

In vitro activities of mutant prevention concentration-targeted concentrations of fluoroquinolones against Staphylococcus aureus in a pharmacodynamic model

scientific article

Inability of a reserpine-based screen to identify strains overexpressing efflux pump genes in clinical isolates of Staphylococcus aureus

scientific article published on 21 December 2008

Indole Based Weapons to Fight Antibiotic Resistance: A Structure-Activity Relationship Study

scientific article

Inhibition of Drug Efflux Pumps in Staphylococcus Aureus : Current Status of Potentiating Existing Antibiotics ⬇️

scientific article published on April 1, 2013

Inhibition of bacterial efflux pumps: a new strategy to combat increasing antimicrobial agent resistance

scientific article published in October 2002

Inhibition of the NorA multi-drug transporter by oxygenated monoterpenes.

scientific article published on 24 August 2016

Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides

scientific article published on 24 May 2008

Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates

scientific article published in February 2004

Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA.

scientific article

Mechanisms of daptomycin resistance in Staphylococcus aureus

scientific article published on 11 September 2006

Mechanisms of in-vitro-selected daptomycin-non-susceptibility in Staphylococcus aureus ⬇️

scientific article published on August 12, 2011

MepR, a repressor of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrate-responsive regulatory protein

scientific article published on April 2006

Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes

scientific article published in October 2008

Multidrug efflux pumps of Gram-positive bacteria

scientific article

Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein

scientific article

Mutagenesis and Modeling To Predict Structural and Functional Characteristics of the Staphylococcus aureus MepA Multidrug Efflux Pump ⬇️

scientific article published on November 21, 2012

Mutations within the mepA operator affect binding of the MepR regulatory protein and its induction by MepA substrates in Staphylococcus aureus

scientific article

N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors

scientific article published on 22 December 2006

Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors

scientific article

Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus

scientific article

Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus

scientific article published in September 2003

Piperazinyl-linked fluoroquinolone dimers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus ⬇️

scientific article published on May 19, 2003

Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus

scientific article published on 01 March 2006

Pyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors.

scientific article

Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance

scientific article published on 13 June 2013

Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues

scientific article published on 9 June 2017

Searching for innovative quinolone-like scaffolds: synthesis and biological evaluation of 2,1-benzothiazine 2,2-dioxide derivatives

Serum Bactericidal Activity of the Methoxyfluoroquinolones Gatifloxacin and Moxifloxacin against Clinical Isolates of Staphylococcus Species: Are the Susceptibility Breakpoints Too High? ⬇️

scientific article published on October 23, 2003

Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

scientific article

Structural differences between paroxetine and femoxetine responsible for differential inhibition of Staphylococcus aureus efflux pumps

scientific article

Structural features of piperazinyl-linked ciprofloxacin dimers required for activity against drug-resistant strains of Staphylococcus aureus

scientific article

Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR

scientific article

Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position

Synergy between gemifloxacin and trimethoprim/sulfamethoxazole against community-associated methicillin-resistant Staphylococcus aureus

scientific article

Synthesis and evaluation of PSSRI-based inhibitors of Staphylococcus aureus multidrug efflux pumps

scientific article

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps

scientific article

Teicoplanin pharmacodynamics in reference to the accessory gene regulator (agr) in Staphylococcus aureus using an in vitro pharmacodynamic model

scientific article published on 8 February 2008

The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives.

scientific article published on 4 July 2016

The Molecular Mechanisms of Allosteric Mutations Impairing MepR Repressor Function in Multidrug-Resistant Strains of Staphylococcus aureus

scientific article

The phenolic diterpene totarol inhibits multidrug efflux pump activity in Staphylococcus aureus

scientific article published on 30 July 2007

Treatment strategies for infective endocarditis.

scientific article published on February 2010

daptomycin activity against Staphylococcus aureus following vancomycin exposure in an in vitro pharmacodynamic model with simulated endocardial vegetations

scientific article

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