Search filters

List of works by Randy Quentin Cron

1.5 Decades Later: Bearing fruits from the ACR/EULAR exchange Program

scientific article

2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features

scientific article published on April 2011

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

scientific article published on 28 August 2015

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

scientific article published on March 2016

A Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.

scientific article published on 15 February 2016

A T cell-specific enhancer of the human CD40 ligand gene

scientific article

A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter

scientific article

A signal achievement in the treatment of arthritis

scientific article published on 01 August 2005

Adolescent Sjogren's syndrome presenting as psychosis: a case series

scientific article published on 11 February 2020

Age and fecal microbial strain-specific differences in patients with spondyloarthritis

scientific article published on 30 January 2018

Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis

scientific article published on 24 March 2018

Alagille Syndrome and Chronic Arthritis: An International Case Series

scientific article published on 17 November 2019

Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis

scientific article

An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infection

scientific article published on 12 December 2012

An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis.

scientific article published on February 2011

Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series

scientific article published on February 2011

Anaphylaxis to etanercept in two children with juvenile idiopathic arthritis

scientific article published on April 2013

Attainment of inactive disease status following initiation of TNF-α inhibitor therapy for juvenile idiopathic arthritis: enthesitis-related arthritis predicts persistent active disease

scientific article

Benefit of Anakinra in Treating Pediatric Secondary Hemophagocytic Lymphohistiocytosis

scientific article published on 26 December 2019

Benefit of fluoroscopically guided intraarticular, long-acting corticosteroid injection for subtalar arthritis in juvenile idiopathic arthritis

scientific article published on 17 April 2007

Benefit of intraarticular corticosteroid injection under fluoroscopic guidance for subtalar arthritis in juvenile idiopathic arthritis.

scientific article published on 15 September 2006

Biologic therapy modifies clinical and laboratory features of macrophage activation syndrome associated with systemic juvenile idiopathic arthritis.

scientific article

Brain cavernomas associated with en coup de sabre linear scleroderma: Two case reports.

scientific article

CD154 transcriptional regulation in primary human CD4 T cells

scientific article

CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophages.

scientific article published on 31 January 2017

CT-guided percutaneous steroid injection for management of inflammatory arthropathy of the temporomandibular joint in children.

scientific article published on January 2007

Cancer risk in childhood-onset systemic lupus

scientific article published on January 2013

Changes in body mass index in children with juvenile idiopathic arthritis treated with tumor necrosis factor inhibitors.

scientific article published on December 2013

Characteristics of coexisting localized scleroderma and inflammatory arthritis

scientific article published on 03 December 2019

Chronic arthritis without uveitis in velocardiofacial syndrome

scientific article published in August 2006

Clinical Orofacial Examination in Juvenile Idiopathic Arthritis: International Consensus-based Recommendations for Monitoring Patients in Clinical Practice and Research Studies

scientific article published on 15 January 2017

Clinical features and correct diagnosis of macrophage activation syndrome.

scientific article published on 16 June 2015

Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of 362 patients.

scientific article published on November 2014

Combination therapy of abatacept and anakinra in children with refractory systemic juvenile idiopathic arthritis: a retrospective case series

scientific article published on 01 January 2011

Consistent transient transfection of DNA into non-transformed human and murine T-lymphocytes

scientific article published on 01 July 1997

Coronavirus is the trigger, but the immune response is deadly

scientific article published on 29 May 2020

Corticosteroid-induced spinal epidural lipomatosis in the pediatric age group: report of a new case and updated analysis of the literature

scientific article

Current treatment for chronic arthritis in childhood.

scientific article

Decreased CD154 expression by neonatal CD4+ T cells is due to limitations in both proximal and distal events of T cell activation.

scientific article published on December 2003

Defining the normal appearance of the temporomandibular joints by magnetic resonance imaging with contrast: a comparative study of children with and without juvenile idiopathic arthritis.

scientific article published on 24 January 2018

Defining the scourge of COVID-19 hyperinflammatory syndrome

scientific article published on 29 September 2020

Delineation of a Novel Pathway That Regulates CD154 (CD40 Ligand) Expression.

scientific article published in September 2003

Delineation of a novel pathway that regulates CD154 (CD40 ligand) expression

scientific article

Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome

scientific article published on 11 August 2017

Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis

scientific article published on 11 July 2019

Development of new classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article

Development of spondyloarthropathy following episodes of macrophage activation syndrome in children with heterozygous mutations in haemophagocytic lymphohistiocytosis-associated genes

Dissecting the heterogeneity of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

scientific article

Dissecting the heterogeneity of macrophage activation syndrome.

scientific article published on 17 September 2014

Does Viral Hemorrhagic Fever Represent Reactive Hemophagocytic Syndrome?

scientific article published in July 2015

Early growth response-1 is required for CD154 transcription

scientific article

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

scientific article published on 24 March 2006

Effectiveness and toxicity of methotrexate in juvenile idiopathic arthritis: comparison of 2 initial dosing regimens.

scientific article

Emergent high fatality lung disease in systemic juvenile arthritis

scientific article published on 27 September 2019

Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR).

scientific article

Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article published on 19 January 2016

FOXP3 inhibits HIV-1 infection of CD4 T-cells via inhibition of LTR transcriptional activity

scientific article published on October 2008

FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression.

scientific article

Fecal metabolomics in pediatric spondyloarthritis implicate decreased metabolic diversity and altered tryptophan metabolism as pathogenic factors

scientific article

Ferritin to Erythrocyte Sedimentation Rate Ratio: Simple Measure to Identify Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis

scientific article published on 13 July 2019

Freshly isolated Thy-1+ dendritic epidermal cells express T cell receptor gamma delta-CD3

scientific article published on 01 November 1990

Genetic defects in cytolysis in macrophage activation syndrome.

scientific article published on January 2014

Guilt by association - what is the true risk of malignancy in children treated with etanercept for JIA?

scientific article published on 16 August 2010

HIV-1, NFAT, and cyclosporin: immunosuppression for the immunosuppressed?

scientific article published in December 2001

High dose Anakinra for treatment of severe neonatal Kawasaki disease: a case report.

scientific article

High doses of infliximab in the management of juvenile idiopathic arthritis.

scientific article published on 15 August 2013

High prevalence of myositis in a southeastern United States pediatric systemic lupus erythematosus cohort.

scientific article published on 9 August 2011

High prevalence of temporomandibular joint arthritis at disease onset in children with juvenile idiopathic arthritis, as detected by magnetic resonance imaging but not by ultrasound

scientific article published on April 2008

Higher-dose Anakinra is effective in a case of medically refractory macrophage activation syndrome

scientific article published in May 2013

Highways to hell: mechanism based management of Cytokine Storm Syndromes

scientific article published on 29 September 2020

Homocysteine levels and disease duration independently correlate with coronary artery calcification in patients with systemic lupus erythematosus

scientific article published on 01 July 2006

Host factor transcriptional regulation contributes to preferential expression of HIV type 1 in IL-4-producing CD4 T cells

scientific article published on 8 August 2012

IL-15 prolongs CD154 expression on human CD4 T cells via STAT5 binding to the CD154 transcriptional promoter

scientific article

Imaging of the temporomandibular joint in juvenile idiopathic arthritis.

scientific article

Intensive care requirement, rather than degree of serum ferritin elevation, predicts mortality in macrophage activation syndrome

scientific article published on 01 September 2012

Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis

scientific article published on 01 October 2006

Intra-articular corticosteroid injections to the temporomandibular joints are safe and appear to be effective therapy in children with juvenile idiopathic arthritis

scientific article

Intravenous anakinra for cytokine storm syndromes - Authors' reply

scientific article published on 21 July 2020

Isolated Arthritis of the Temporomandibular Joint as the Initial Manifestation of Juvenile Idiopathic Arthritis.

scientific article published on September 2017

Juvenile idiopathic arthritis classification criteria: loopholes and diagnosis software.

scientific article published in January 2007

Kill or be killed

scientific article published on 01 June 2015

Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation.

scientific article published on 23 October 2013

MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration

scientific article published on June 2013

Macrophage Activation Syndrome

scientific article published on 25 August 2015

Macrophage Activation Syndrome and Secondary Hemophagocytic Lymphohistiocytosis in Childhood Inflammatory Disorders: Diagnosis and Management

scientific article published on 01 February 2020

Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment.

scientific article published on 15 March 2012

Magnetic Resonance Imaging Findings following Intraarticular Infliximab Therapy for Refractory Temporomandibular Joint Arthritis among Children with Juvenile Idiopathic Arthritis

scientific article published on September 2015

Malignancy in Pediatric-onset Systemic Lupus Erythematosus.

scientific article published on August 2017

Management of temporomandibular joint arthritis in adult rheumatology practices: a survey of adult rheumatologists

scientific article published on 20 August 2012

Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis

scientific article published on 01 May 1998

NFAT1 enhances HIV-1 gene expression in primary human CD4 T cells

scientific article published on March 2000

NF‐ATc1 levels are increased in murine and human lupus T cells: Comment on the article by Kyttaris et al

scientific article published on October 27, 2011

Neither cell-surface nor soluble CD154 levels are associated with coronary artery disease in systemic lupus erythematosus

scientific article published on 01 February 2008

Novel UNC13D intronic variant disrupting a NFκB enhancer in a patient with recurrent macrophage activation syndrome and systemic juvenile idiopathic arthritis.

scientific article published on 6 February 2018

Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis.

scientific article published on March 2007

Octamer proteins inhibit IL-4 gene transcription in normal human CD4 T cells

scientific article published on 01 December 2001

On the alert for cytokine storm: Immunopathology in COVID-19

scientific article published on 15 April 2020

One-two punch of cytokine storm syndrome

scientific article published on 01 August 2020

Overexpression of octamer transcription factors 1 or 2 alone has no effect on HIV-1 transcription in primary human CD4 T cells

scientific article published in April 2004

Patterns of B Cell Repletion Following Rituximab Therapy in a Pediatric Rheumatology Cohort

scientific article published on 27 August 2019

Pediatric macrophage activation syndrome, recognizing the tip of the Iceberg

scientific article published on 03 December 2019

Pediatric rheumatology for the adult rheumatologist I: therapy and dosing for pediatric rheumatic disorders

scientific article

Pediatric rheumatology for the adult rheumatologist II: uveitis in juvenile idiopathic arthritis.

scientific article published on August 2007

Pediatric rheumatology infusion center: report on therapeutic protocols and infusions given over 4 Years with focus on adverse events over 1 Year.

scientific article

Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article published in October 2014

Picture of the month: anaplastic large cell lymphoma with hemophagocytic lymphohistiocytosis

scientific article published in November 2006

Polymorphisms and diversity of T-cell receptor-gamma proteins expressed in mouse spleen

scientific article published in January 1990

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two: Genoa, Italy. 28 September – 01 October 2016.

scientific article published on 30 May 2017

Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis.

scientific article

Reactive arthritis of the temporomandibular joints and cervical spine in a child

scientific article published on 4 April 2007

Reciprocal regulation of the nuclear factor of activated T cells and HIV-1.

scientific article published on May 2004

Regulation of the murine Nfatc1 gene by NFATc2.

scientific article

Regulatory CD4 T cells inhibit HIV-1 expression of other CD4 T cell subsets via interactions with cell surface regulatory proteins

scientific article published on 8 January 2018

Research priorities in pediatric rheumatology: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus

scientific article published on April 2008

Response to: 'Successful treatment of plasma exchange for refractory systemic juvenile idiopathic arthritis complicated with macrophage activation syndrome and severe lung disease' by Sato et al

scientific article published on 21 April 2020

Results of a multinational survey regarding the diagnosis and treatment of temporomandibular joint involvement in juvenile idiopathic arthritis

scientific article published on 25 January 2014

Retinal vasculitis in two pediatric patients with systemic lupus erythematosus: a case report.

scientific article published on 04 June 2013

Risk Factors for Intraarticular Heterotopic Bone Formation in the Temporomandibular Joint in Juvenile Idiopathic Arthritis

scientific article published on 15 May 2018

Risk factors for temporomandibular joint arthritis in children with juvenile idiopathic arthritis

scientific article published on 15 May 2012

Risk of tuberculosis among Alabama children and adolescents treated with tumor necrosis factor inhibitors: a retrospective study

scientific article

Risk, Timing and Predictors of Disease Flare after Discontinuation of Anti-Tumor Necrosis Factor (TNF) Therapy in Children with Polyarticular Forms of Juvenile Idiopathic Arthritis (JIA) in Clinical Inactive Disease.

scientific article published on 31 March 2018

Rituximab therapy for severe refractory chronic Henoch-Schönlein purpura.

scientific article published on July 2009

Rituximab treatment for chronic steroid-dependent Henoch-Schonlein purpura: 8 cases and a review of the literature

scientific article published on 14 November 2018

SEVERE NEONATAL CORONAVIRUS DISEASE 2019 PRESENTING AS ACUTE RESPIRATORY DISTRESS SYNDROME

scientific article published on 12 August 2020

Safety and efficacy of intra-articular infliximab therapy for treatment-resistant temporomandibular joint arthritis in children: a retrospective study.

scientific article published on 05 December 2012

Safety and efficacy of rituximab in childhood-onset systemic lupus erythematosus and other rheumatic diseases

scientific article published on 15 January 2015

Sarcoidosis in a young child with Alagille syndrome: a case report

scientific article published on 31 August 2012

Sensitivity and specificity of current diagnostic guidelines in children with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

Sensitivity and specificity of current diagnostic guidelines in children with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

scientific article published on 14 September 2011

Septic abscess in a child with juvenile idiopathic arthritis receiving anti-tumor necrosis factor-alpha

scientific article published on 01 April 2006

Serum S100A8/A9 and S100A12 Levels in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis: Relationship to Maintenance of Clinically Inactive Disease During Anti-Tumor Necrosis Factor Therapy and Occurrence of Disease Flare After Disc

scientific article published on 24 January 2019

Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome

scientific article published on 04 May 2020

Sjögren syndrome in a child: favorable response of the arthritis to TNFalpha blockade

scientific article published on 4 January 2006

Standardizing Terminology and Assessment for Orofacial Conditions in Juvenile Idiopathic Arthritis: International, Multidisciplinary Consensus-based Recommendations

scientific article published on 15 January 2019

Successful treatment of pediatric IgG4 related systemic disease with mycophenolate mofetil: case report and a review of the pediatric autoimmune pancreatitis literature.

scientific article

Successful treatment of pediatric Tolosa-Hunt syndrome with adalimumab

scientific article published on 03 December 2019

Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients

scientific article published on 07 August 2010

Sweet syndrome as an initial presentation in a child with systemic lupus erythematosus

scientific article published on 01 January 2005

Teamwork, A Novel Concept During an Infectious Pandemic?

scientific article published on 08 June 2020

Temporomandibular joint arthritis in juvenile idiopathic arthritis, now what?

scientific article published on 25 April 2018

Temporomandibular joint arthritis in juvenile idiopathic arthritis: the forgotten joint

scientific article published on September 2006

Temporomandibular joint arthritis in patients with non-JIA childhood arthritis.

scientific article

Temporomandibular joint arthritis in pediatric sjogren disease and sarcoidosis

scientific article published on 01 October 2011

The Immunology of Macrophage Activation Syndrome

scientific article published on 01 February 2019

The Question of Whether to Remain on Therapy for Chronic Rheumatic Diseases in the Setting of the Covid-19 Pandemic

scientific article published on 25 April 2020

The Rheumatologist's Role in Covid-19

scientific article published on 24 March 2020

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells

scientific article

The genetics of macrophage activation syndrome

scientific article published on 15 April 2020

The human gp39 promoter. Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation.

scientific article

The impact of Nucleofection® on the activation state of primary human CD4 T cells

scientific article published on 5 June 2014

The microbiota in pediatric rheumatic disease: epiphenomenon or therapeutic target?

scientific article

The temporomandibular joint in juvenile idiopathic arthritis: frequently used and frequently arthritic

scientific article published on 29 May 2009

The use of anakinra in the treatment of secondary hemophagocytic lymphohistiocytosis

scientific article published on 29 July 2020

Towards Establishing a Standardized Magnetic Resonance Imaging Scoring System for Temporomandibular Joints in Juvenile Idiopathic Arthritis.

scientific article published on 13 August 2017

Treating Covid-19 at the Inflection Point

scientific article published on 25 May 2020

Treatment of juvenile idiopathic arthritis in the biologic age.

scientific article published on 05 July 2013

Treatment of juvenile idiopathic arthritis: a revolution in care

scientific article

Treatment of pediatric localized scleroderma with methotrexate.

scientific article published in March 2006

Update of the results of a multinational survey regarding diagnosis and treatment of the temporomandibulare joint involvement in juvenile idiopathic arthritis- reflection of the day to day practice

scientific article published on 14 September 2011

Ustekinumab as a Therapeutic Option for Children With Refractory Enthesitis-Related Arthritis

scientific article published in August 2016

Utility of corticosteroid injection for temporomandibular arthritis in children with juvenile idiopathic arthritis

scientific article published in November 2005

Weathering a Macrophage Storm

scientific article published on 01 July 2017

Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

scientific article published on 23 November 2015