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List of works by Ian T Johnson

2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

scientific article

A comparison of the effects of soya isoflavonoids and fish oil on cell proliferation, apoptosis and the expression of oestrogen receptors alpha and beta in the mammary gland and colon of the rat.

scientific article published on 12 December 2008

Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter

scientific article published in April 2003

Acetylcholine-induced calcium signaling along the rat colonic crypt axis

scientific article published on 01 November 1998

Acid microclimate in coeliac and Crohn's disease: a model for folate malabsorption

scientific article published on August 1, 1978

Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29.

scientific article published on October 1993

Allyl-isothiocyanate causes mitotic block, loss of cell adhesion and disrupted cytoskeletal structure in HT29 cells.

scientific article published on 19 March 2004

Alternative methods of animal sacrifice: The effect on intestinal function in vitro ⬇️

scientific article published on March 15, 1976

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium

scientific article published on February 2015

Anticarcinogenic effects of diet-related apoptosis in the colorectal mucosa.

scientific article

Anticarcinogenic factors in plant foods: a new class of nutrients?

scientific article published in January 1994

Antioxidants and anticarcinogens ⬇️

scientific article published on May 1, 1998

Apoptosis can be detected in attached colonic adenocarcinoma HT29 cells using annexin V binding, but not by TUNEL assay or sub-G0 DNA content

scientific article published on 01 July 2000

Brown Norway rat model of food allergy: effect of plant components on the development of oral sensitization

scientific article published on 01 January 1996

Cancers of the gut and Western ills

scientific article published on 01 March 2005

Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro

scientific article published on 26 August 2012

Cruciferous Vegetables and Risk of Cancers of the Gastrointestinal Tract

scientific article published on 30 April 2018

Cyclo-oxygenase-2 expression in Barrett's oesophageal carcinogenesis: an immunohistochemical study.

scientific article published on February 2003

Cytotoxic and clastogenic effects of benzyl isothiocyanate towards cultured mammalian cells.

scientific article published on January 1995

Cytotoxicity and genotoxicity of diallyl sulfide and diallyl disulfide towards Chinese hamster ovary cells.

scientific article published on March 1997

Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake

article

Diet-associated inflammation modulates inflammation and WNT signaling in the rectal mucosa, and the response to supplementation with dietary fibre

scientific article published on 28 October 2020

Dietary carbohydrates: a review of international recommendations and the methods used to derive them.

scientific article published on 25 April 2018

Dietary lactitol fermentation increases circulating peptide YY and glucagon-like peptide-1 in rats and humans

scientific article

Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon

scientific article published in April 1999

Differences in intestinal protein synthesis and cellular proliferation in well-nourished rats consuming conventional laboratory diets.

scientific article

Effect of dietary supplements of guar gum and cellulose on intestinal cell proliferation, enzyme levels and sugar transport in the rat

scientific article published on 01 November 1984

Effect of eicosapentaenoic acid on the proliferation and incidence of apoptosis in the colorectal cell line HT29.

scientific article

Effect of gel-forming gums on the intestinal unstirred layer and sugar transport in vitro

scientific article published on May 1981

Effect of oat gum on the physical properties of the gastrointestinal contents and on the uptake of D-galactose and cholesterol by rat small intestine in vitro

scientific article published on 01 July 1989

Effect of saponin on the transmucosal passage of beta-lactoglobulin across the proximal small intestine of normal and beta-lactoglobulin-sensitised rats

scientific article published on 01 February 1997

Effects of Brassica vegetable juice on the induction of apoptosis and aberrant crypt foci in rat colonic mucosal crypts in vivo

scientific article published in March 2003

Effects of Brussels sprout juice on the cell cycle and adhesion of human colorectal carcinoma cells (HT29) in vitro

scientific article published in May 2005

Effects of dietary fish oil supplementation on the phospholipid composition and fluidity of cell membranes from human volunteers

scientific article published on 01 January 1999

Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study.

scientific article

Effects of saponins and glycoalkaloids on the permeability and viability of mammalian intestinal cells and on the integrity of tissue preparations in vitro

scientific article published on 01 April 1996

Effects of some purified saponins on transmural potential difference in mammalian small intestine

scientific article published on 01 January 1989

Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals

scientific article published on 11 January 2017

Emerging diet-related surrogate end points for colorectal cancer: UK Food Standards Agency diet and colonic health workshop report

scientific article published on February 2004

Environment, diet and CpG island methylation: epigenetic signals in gastrointestinal neoplasia.

scientific article published on 26 September 2007

Epigenetic and antioxidant effects of dietary isothiocyanates and selenium: potential implications for cancer chemoprevention

scientific article published on 06 March 2012

Fermentable carbohydrate modulates postprandial enteroglucagon and gastrin release in rats.

scientific article published in May 1996

Gastrointestinal adaptation in response to soluble non-available polysaccharides in the rat.

scientific article

Genotoxic effects of crude juices from Brassica vegetables and juices and extracts from phytopharmaceutical preparations and spices of cruciferous plants origin in bacterial and mammalian cells.

scientific article published on September 1996

Glucosinolates: bioavailability and importance to health

scientific article

Gut health, genetics and personalised nutrition.

scientific article published on October 2007

Habitual intake of fruits and vegetables amongst patients at increased risk of colorectal neoplasia

scientific article published in March 1997

Hexose absorption from jejunal loops in situ in zinc-deficient and Zn-supplemented rats

scientific article published on 01 January 1986

Hexose transport and mucosal morphology in the small intestine of the zinc-deficient rat.

scientific article published in September 1984

Hydrolysis by lactase phlorizin hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro

scientific article published in March 2003

Identification of the Eph receptor pathway as a novel target for eicosapentaenoic acid (EPA) modification of gene expression in human colon adenocarcinoma cells (HT-29).

scientific article published on 12 July 2010

Impact of resistant starch on colonic crypt cytokinetics and cell cycle regulatory genes

scientific article published in March 2009

In vitro estimation of iron availability from a range of plant foods: influence of phytate, ascorbate and citrate

scientific article published on 01 March 1987

Increased induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats fed diets containing purified genistein or genistein-rich soya protein

scientific article published in December 2000

Influence of viscous incubation media on the resistance to diffusion of the intestinal unstirred water layer in vitro.

scientific article

Inhibition of dimethylhydrazine-induced aberrant crypt foci and induction of apoptosis in rat colon following oral administration of the glucosinolate sinigrin.

scientific article published in February 1998

Intestinal cellular proliferation and protein synthesis in zinc-deficient rats.

scientific article

Intestinal microflora and gastrointestinal adaptation in the rat in response to non-digestible dietary polysaccharides.

scientific article

Intestinal microflora, morphology and enzyme activity in zinc-deficient and Zn-supplemented rats

scientific article

Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1).

scientific article

K-ras mutations, rectal crypt cells proliferation, and meat consumption in patients with left-sided colorectal carcinoma

scientific article published in February 2000

Metabolism of the soybean isoflavone glycoside genistin in vitro by human gut bacteria and the effect of prebiotics

scientific article published in September 2003

Metabolomics of Fecal Extracts Detects Altered Metabolic Activity of Gut Microbiota in Ulcerative Colitis and Irritable Bowel Syndrome

scientific article published on 08 August 2011

Microbial species involved in production of 1,2-sn-diacylglycerol and effects of phosphatidylcholine on human fecal microbiota.

scientific article published on September 2004

Micronutrients and cancer.

scientific article

New approaches to the role of diet in the prevention of cancers of the alimentary tract.

scientific article published in July 2004

Non-digestible carbohydrates supplementation increases miR-32 expression in the healthy human colorectal epithelium: A randomized controlled trial

scientific article published on 18 April 2017

Non-steroidal anti-inflammatory drugs, lower oesophageal sphincter-relaxing drugs and oesophageal cancer. A case-control study

scientific article (publication date: 2006)

Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa

scientific article published on 6 December 2012

Olive oil supplementation in healthy adults: effects in cell membrane fatty acid composition and platelet function.

scientific article published in January 1998

Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa

scientific article published on 15 April 2010

Pea (Pisum sativum L.) protease inhibitors from the Bowman-Birk class influence the growth of human colorectal adenocarcinoma HT29 cells in vitro

scientific article

Phytochemicals and cancer.

scientific article

Plant anticarcinogens ⬇️

scientific article published on 01 December 1997

Polyunsaturated fatty acids of the n - 3 series influence intestinal crypt cell production in rats

scientific article

Procyanidin effects on oesophageal adenocarcinoma cells strongly depend on flavan-3-ol degree of polymerization

scientific article

Procyanidin induces apoptosis of esophageal adenocarcinoma cells via JNK activation of c-Jun

scientific article published on 28 January 2014

Proteomic analysis reveals field-wide changes in protein expression in the morphologically normal mucosa of patients with colorectal neoplasia

scientific article published in July 2006

Proteomic methodological recommendations for studies involving human plasma, platelets, and peripheral blood mononuclear cells

scientific article

Proteomics in nutrition research: principles, technologies and applications

scientific article published in September 2005

Quantitative profiling of CpG island methylation in human stool for colorectal cancer detection

scientific article published on 13 July 2012

Quercetin glucosides interact with the intestinal glucose transport pathway

scientific article published in July 1998

Recent advances in understanding the role of diet and obesity in the development of colorectal cancer.

scientific article published on 09 March 2011

Stimulated efflux of folic acid from the mucosal epithelium of the rat in vitro

scientific article published on 01 August 1974

Suppression of intestinal crypt cell proliferation and aberrant crypt foci by dietary quercetin in rats

scientific article published in January 2002

Supra-physiological folic acid concentrations induce aberrant DNA methylation in normal human cells in vitro.

scientific article published on July 2012

Surface area and effect of drying temperature related to dry weight of jejunal tissue in rat.

scientific article published in December 1974

Synthetic and naturally occurring COX-2 inhibitors suppress proliferation in a human oesophageal adenocarcinoma cell line (OE33) by inducing apoptosis and cell cycle arrest.

scientific article published on 20 May 2004

Systematic review: Cyclo-oxygenase-2 in human oesophageal adenocarcinogenesis.

scientific article published on November 2006

The biological effects and digestible energy value of a sugar-beet fibre preparation in the rat.

scientific article published on July 1990

The cancer risk related to meat and meat products.

scientific article published on 18 December 2016

The clastogenic effects of isothiocyanates

scientific article

The effect of Gypsophila saponins in the diet on mineral status and plasma cholesterol concentration in the rat.

scientific article

The effect of diet on the intestinal epigenome

scientific article published on April 2014

The effect of dietary protein source and guar gum on gastrointestinal growth and enteroglucagon secretion in the rat

scientific article published on 01 July 1987

The effect of guar gum on the viscosity of the gastrointestinal contents and on glucose uptake from the perfused jejunum in the rat

scientific article published on 01 September 1981

The effect of prolonged dietary supplementation with guar gum on subsequent iron absorption and retention in rats

scientific article published on 01 March 1987

The effects of and interactions between fermentable dietary fiber and lipid in germfree and conventional mice

scientific article published on 01 June 1995

The influence of cooked kidney beans (Phaseolus vulgaris) on intestinal cell turnover and faecal nitrogen excretion in the rat

scientific article published on 01 May 1983

The influence of guar gum on intestinal cholesterol transport in the rat.

scientific article

The influence of guar gum on the movements of inulin, glucose and fluid in rat intestine during perfusion in vivo

scientific article published on 01 April 1983

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

scientific article

Transcriptomics and proteomics show that selenium affects inflammation, cytoskeleton, and cancer pathways in human rectal biopsies

scientific article published on 21 April 2016

TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death

scientific article published on 20 July 2012

Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota.

scientific article

Understanding the association between diet and nutrition in upper gastrointestinal cancer

scientific article published on 14 September 2015

Using smart card technology to monitor the eating habits of children in a school cafeteria: 1. Developing and validating the methodology

scientific article

Using smart card technology to monitor the eating habits of children in a school cafeteria: 2. The nutrient contents of all meals chosen by a group of 8- to 11-year-old boys over 78 days

scientific article published in August 2005

Using smart card technology to monitor the eating habits of children in a school cafeteria: 3. The nutritional significance of beverage and dessert choices

scientific article published in August 2005

Validation of a simple technique for the detection of abnormal mucosal cell replication in humans ⬇️

scientific article published on 01 July 1994

Variation in protein levels obtained from human blood cells and biofluids for platelet, peripheral blood mononuclear cell, plasma, urine and saliva proteomics

scientific article

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