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List of works by Sebastian Moran

A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition

scientific article published on 08 August 2014

A DNA methylation map of human cancer at single base-pair resolution.

scientific article published on 05 June 2017

A DNA methylation-based definition of biologically distinct breast cancer subtypes

scientific article published on 5 November 2014

A Prognostic DNA Methylation Signature for Stage I Non–Small-Cell Lung Cancer

article

A landscape of pharmacogenomic interactions in cancer.

scientific article published on 05 July 2016

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

scientific article published on 7 October 2015

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

scientific article published on 20 December 2012

Arachidonic and oleic acid exert distinct effects on the DNA methylome.

scientific article published on 18 April 2016

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

scientific article

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors

scientific article published on 7 September 2017

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 01 September 2018

DNA methylation contributes to natural human variation

scientific article published on August 2013

DNA methylation dynamics in human carotid plaques after cerebrovascular events

scientific article published on 18 June 2015

DNA methylation map of human atherosclerosis

scientific article published on 4 August 2014

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

scientific article

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

scientific article

DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 05 May 2018

DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia

scientific article

Distinct DNA methylomes of newborns and centenarians

scientific article

EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC

scientific article published on 31 January 2019

Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer

scientific article published on 10 August 2016

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

scientific article published on June 2015

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

scientific article published on 27 November 2015

Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia.

scientific article published on 27 March 2017

Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance

scientific article

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

scientific article published on 26 August 2016

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.

scientific article published on 26 January 2016

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

scientific article

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

scientific article published on 27 June 2016

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

scientific article published on 30 October 2012

Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells

scientific article published on 10 April 2017

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

scientific article

Higher prevalence of cerebral white matter hyperintensities in homozygous APOE-ɛ4 allele carriers aged 45-75: Results from the ALFA study.

scientific article published in January 2017

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns.

scientific article published on 19 January 2016

Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study

scientific article published on 06 April 2020

Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study

scientific article published on December 2015

Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis.

scientific article

Journal club: epigenetic profiling to classify cancer of unknown primary - Authors' reply.

scientific article

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

scientific article published on 24 July 2015

Linkage of DNA Methylation Quantitative Trait Loci to Human Cancer Risk

Look-alike humans identified by facial recognition algorithms show genetic similarities

scholarly article

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

scientific article

Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines

scientific article

MicroRNA-654-5p suppresses ovarian cancer development impacting on MYC, WNT and AKT pathways

scientific article published on 05 July 2019

Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer

scientific article published on 21 November 2012

Obesity and menopause modify the epigenomic profile of breast cancer

scientific article published on 25 April 2017

Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.

scientific article

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.

scientific article

Technologies for Deciphering Epigenomic DNA Patterns

scientific article published on 01 January 2017

The ALFA project: A research platform to identify early pathophysiological features of Alzheimer's disease

scientific article published on 3 March 2016

The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

scientific article published on 27 February 2015

The NCI-60 Methylome and Its Integration into CellMiner

scientific article

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray.

scientific article published on 14 April 2014

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

scientific article published on June 2011

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

scientific article published on 17 December 2015

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer.

scientific article

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

scientific article published on 20 January 2017

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

scientific article

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

scientific article

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