List of works by Fares Al-Ejeh

'Omics Approaches in Breast Cancer Research and Clinical Practice

scientific article published on November 2016

A short ERK5 isoform modulates nucleocytoplasmic shuttling of active ERK5 and associates with poor survival in breast cancer

A simplified suite of methods to evaluate chelator conjugation of antibodies: effects on hydrodynamic radius and biodistribution

scientific article

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

scientific article published on 18 June 2018

APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy

scientific article

Abstract LB-116: Cep55, a master regulator of cytokinesis in breast cancer pathogenesis

Abstract P5-04-17: From transcriptome meta-analysis to targeted therapies in triple negative breast cancer

Abstract P6-09-47: The development of personalized diagnostic tests and therapeutic strategies in breast cancer

article

Abstract P6-10-06: Rational combination therapy against triple-negative breast cancer

Application of molecular findings to the diagnosis and management of breast disease: recent advances and challenges

scientific article published on 24 November 2010

Breast cancer metastasis to gynaecological organs: a clinico-pathological and molecular profiling study

Breast cancer stem cells: treatment resistance and therapeutic opportunities

scientific article published on 10 February 2011

Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient.

scientific article published on 21 February 2018

Chemotherapy synergizes with radioimmunotherapy targeting La autoantigen in tumors

scientific article

Clinicopathologic significance of nuclear HER4 and phospho-YAP(S127) in human breast cancers and matching brain metastases

scientific article published on 31 July 2020

Differential gene expression of tumor-infiltrating CD8+ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis

scientific article published on 01 September 2020

Eph family co-expression patterns define unique clusters predictive of cancer phenotype

scientific article

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia

scientific article published on 17 June 2015

EphA3 Pay-Loaded Antibody Therapeutics for the Treatment of Glioblastoma

scientific article published on 17 December 2018

EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia

scientific article published on 6 December 2016

EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme.

scientific article

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

scientific article published on 02 May 2022

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

scientific article

G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis

scientific article published on 19 June 2017

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma

scientific article published on 16 May 2014

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

scientific article published on 06 September 2010

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Immunotargeting of Functional Nanoparticles for MRI detection of Apoptotic Tumor Cells

scientific article published on 01 February 2009

In vivo targeting of dead tumor cells in a murine tumor model using a monoclonal antibody specific for the La autoantigen

scientific article

Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance

scientific article published on 14 July 2015

Kinetic analysis of plasminogen activator inhibitor type-2: urokinase complex formation and subsequent internalisation by carcinoma cell lines

scientific article published on July 2004

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

scientific article

Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.

scientific article published on August 2017

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer

scientific article published on 04 July 2016

MEK5-ERK5 pathway associates with poor survival of breast cancer patients after systemic treatments

scientific article

MITF and BRN2 contribute to metastatic growth after dissemination of melanoma

scientific article published on 7 September 2017

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

scientific article

Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer.

scientific article

Molecular Diagnostics: Translation from Discovery to Clinical Practice

Multidimensional phenotyping of breast cancer cell lines to guide preclinical research

scientific article

Multifunctional core-shell magnetic cisplatin nanocarriers

scientific article

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.

scientific article published on 10 October 2011

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

scientific article

Nutlin-3a is a potential therapeutic for ewing sarcoma

scientific article published on 23 November 2010

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells.

scientific article published on 12 June 2019

PDTB-19. EphA RECEPTOR TYROSINE KINASES AS TARGETS FOR THERAPY IN PAEDIATRIC MEDULLOBLASTOMA

Plasma functionalized PDMS microfluidic chips: towards point-of-care capture of circulating tumor cells

Postchemotherapy and Tumor-Selective Targeting with the La-Specific DAB4 Monoclonal Antibody Relates to Apoptotic Cell Clearance

scientific article published on 27 March 2014

Preclinical evaluation of 213Bi-labeled plasminogen activator inhibitor type 2 in an orthotopic murine xenogenic model of human breast carcinoma

scientific article published in January 2007

Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications

scientific article published on 17 February 2022

Proteomic Analysis of the Breast Cancer Brain Metastasis Microenvironment.

scientific article published on 22 May 2019

Quinazolinone derivatives as inhibitors of homologous recombinase RAD51.

scientific article

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

scientific article published on 05 August 2016

Rad51 supports triple negative breast cancer metastasis

scientific article published in May 2014

SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication

scientific article

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

scientific article

The La Autoantigen Is a Malignancy-Associated Cell Death Target That Is Induced by DNA-Damaging Drugs

scientific article published on 01 September 2007

The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®.

scientific article published on 04 January 2014

Tocotrienol as a potential anticancer agent

scientific article

Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor

scientific article published on 5 April 2013

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib

scientific article published on 13 May 2015

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