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List of works by Muthu Periasamy

A major role for AT1b receptor in mouse mesenteric resistance vessels and its distribution in heart and neuroendocrine tissues.

scientific article

A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in mice

scientific article published on 12 March 2007

A novel E box/AT-rich element is required for muscle-specific expression of the sarcoplasmic reticulum Ca2+-ATPase (SERCA2) gene ⬇️

scientific article published on February 15, 1998

A simple method of synthesis of (+/-)-2,3-diarylpiperazines and a novel method of resolution of (+/-)-2,3-diphenylpiperazine

scientific article published on 01 April 2006

AT1b receptor predominantly mediates contractions in major mouse blood vessels

scientific article published on 16 October 2003

Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility

scientific article

Ablation of sarcolipin results in atrial remodeling ⬇️

scientific article published on April 11, 2012

Ablation of smooth muscle myosin heavy chain SM2 increases smooth muscle contraction and results in postnatal death in mice

scholarly article

Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity

scientific article published on 20 November 2003

Acute dim light at night increases body mass, alters metabolism, and shifts core body temperature circadian rhythms

scientific article published on 16 June 2014

Adenoviral-mediated serca gene transfer into cardiac myocytes: how much is too much?

article

Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium

scientific article published on 01 February 1993

Altered dose response to beta-agonists in SERCA1a-expressing hearts ex vivo and in vivo

scientific article published in September 2002

Altered force-frequency response in non-failing hearts with decreased SERCA pump-level

scientific article published in September 2003

An improved DNA isolation method and PCR protocol for efficient detection of multicomponents of begomovirus in legumes

scientific article published on 17 September 2007

Analysis of sarcoplasmic reticulum Ca2+ transport and Ca2+ ATPase enzymatic properties using mouse cardiac tissue homogenates

scientific article published on 01 May 1999

Association of Chairs of Departments of Physiology 2012 survey results

Calcineurin and the heartbeat, an evolving story

scientific article published on 01 March 2002

Calcium dynamics in the failing heart: restoration by beta-adrenergic receptor blockade

scientific article published on 20 March 2003

Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.

scientific article

Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes ⬇️

scientific journal article

Carvedilol effectively blocks oxidative stress-mediated downregulation of sarcoplasmic reticulum Ca2+-ATPase 2 gene transcription through modification of Sp1 binding

scientific article published in March 2005

Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes

scientific article

Characterization of a developmentally regulated perinatal myosin heavy-chain gene expressed in skeletal muscle ⬇️

scientific article published on November 10, 1984

Characterization of a mammalian smooth muscle myosin heavy chain cDNA clone and its expression in various smooth muscle types

scientific article

Characterization of a mammalian smooth muscle myosin heavy-chain gene: complete nucleotide and protein coding sequence and analysis of the 5' end of the gene

scientific article published in December 1991

Characterization of a phosphoprotein phosphatase activity in ribonucleoprotein particles from HeLa cell nuclei

scientific article published on December 21, 1977

Characterization of cDNA and genomic sequences corresponding to an embryonic myosin heavy chain

scientific article published in December 1985

Characterization of promoter elements of the rabbit cardiac sarcoplasmic reticulum Ca(2+)-ATPase gene required for expression in cardiac muscle cells

scientific article published on 01 October 1993

Characterization of rabbit cardiac sarco(endo)plasmic reticulum Ca2(+)-ATPase gene

scientific article published on March 1990

Cloning DNA fragments between two adjacent/overlapping restriction sites using a "positive stuffer".

scientific article

Cloning and characterization of the gene encoding rabbit cardiac calsequestrin

scientific article published on December 1991

Collagen synthesis inhibitors disrupt embryonic cardiocyte myofibrillogenesis and alter the expression of cardiac specific genes in vitro

scientific article published in June 1994

Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state

scientific article published on 01 January 2003

Complete nucleotide and encoded amino acid sequence of a mammalian myosin heavy chain gene. Evidence against intron-dependent evolution of the rod.

scientific article published in August 1986

Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.

scientific article published in December 2005

Deletion of SM-B, the high ATPase isoform of myosin, upregulates the PKC-mediated signal transduction pathway in murine urinary bladder smooth muscle.

scientific article published on 03 December 2008

Determinants of frequency-dependent contraction and relaxation of mammalian myocardium.

scientific article published on 28 August 2007

Detrimental effects of thyroid hormone analog DITPA in the mouse heart: increased mortality with in vivo acute myocardial ischemia-reperfusion

scientific article

Differential expression of SM1 and SM2 myosin isoforms in cultured vascular smooth muscle

scientific article published on 01 March 1992

Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology

scientific article published on 18 May 2007

Differential regulation of antioxidant enzymes in response to oxidants

scientific article published on December 1991

Differential vasoconstrictions induced by angiotensin II: role of AT1 and AT2 receptors in isolated C57BL/6J mouse blood vessels.

scientific article published on 7 August 2003

Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function

scientific article published in December 2000

Effect of angiotensin-converting enzyme inhibition on protein kinase C and SR proteins in heart failure

scientific article published on 01 January 1999

Effect of cardiac resynchronization therapy on myocardial gene expression in patients with nonischemic dilated cardiomyopathy.

scientific article published in May 2007

Effect of thyroid hormone on the expression of mRNA encoding sarcoplasmic reticulum proteins

scientific article published on 01 August 1991

Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin

scientific article published on 14 September 2006

Effects of insulin resistance on skeletal muscle growth and exercise capacity in type 2 diabetic mouse models.

scientific article published on 14 January 2014

Effects of thyroid hormone on left ventricular performance and regulation of contractile and Ca(2+)-cycling proteins in the baboon. Implications for the force-frequency and relaxation-frequency relationships

scientific article

Efficient cloning method that selects the recombinant clones

scientific article published on 01 August 1997

Endothelin-1-induced responses in isolated mouse vessels: the expression and function of receptor types

scientific article published on 8 April 2004

Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice ⬇️

scientific article published on June 22, 2011

Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase

scientific article published on November 1998

Evolutionarily conserved promoter region containing CArG*-like elements is crucial for smooth muscle myosin heavy chain gene expression

scientific article published on 01 March 1998

Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus.

scientific article

Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cβ in mice

scientific article

Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction.

scientific article

Expression of myogenic factors in denervated chicken breast muscle: isolation of the chicken Myf5 gene.

scientific article

Fast skeletal muscle myosin light chains 1 and 3 are produced from a single gene by a combined process of differential RNA transcription and splicing

scientific article published in November 1984

Frequency-dependent changes in calcium cycling and contractile activation in SERCA2a transgenic mice

scientific article published on 01 April 2000

Frequency-dependent contractile strength in mice over- and underexpressing the sarco(endo)plasmic reticulum calcium-ATPase

scientific article published on 25 January 2007

Functional consequences of stably expressing a mutant calsequestrin (CASQ2D307H) in the CASQ2 null background.

scientific article published on 7 October 2011

Functional interaction between calsequestrin and ryanodine receptor in the heart ⬇️

scientific article published on October 30, 2012

GLUT12 functions as a basal and insulin-independent glucose transporter in the heart

scientific journal article

Gene amplification and transcriptional upregulation of the sarco/endoplasmic reticulum Ca2+ transport ATPase in thapsigargin-resistant hamster smooth muscle cells.

scientific article published on October 1998

Genetic and non-genetic control of myocardial calcium.

scientific article

Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart

scientific article published on 11 March 2004

Growth and differentiation of smooth muscle cells during vascular development ⬇️

scientific article published on April 1, 1996

High gender -specific susceptibility to curare- a neuromuscular blocking agent.

scientific article published on January 2013

Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis

scientific article (publication date: December 1993)

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism ⬇️

scientific article published on February 20, 2012

Identification of a novel smooth muscle myosin heavy chain cDNA: isoform diversity in the S1 head region

scientific journal article

Identification of functional promoter elements in the rabbit smooth muscle myosin heavy chain gene.

scientific article published on December 1994

Identification of targeted embryonic stem cells using long-distance PCR

scientific article published on 01 September 1997

Identification of two types of smooth muscle myosin heavy chain isoforms by cDNA cloning and immunoblot analysis

scientific article

Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene

scientific article published on 01 January 1999

Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure

scientific article published on 17 May 2007

Intra-sarcoplasmic reticulum Ca2+ oscillations are driven by dynamic regulation of ryanodine receptor function by luminal Ca2+ in cardiomyocytes

scientific article published on 24 August 2009

Intron positions are conserved in the 5' end region of myosin heavy-chain genes

scientific article published in January 1985

Is reduced SERCA2a expression detrimental or beneficial to postischemic cardiac function and injury? Evidence from heterozygous SERCA2a knockout mice

scientific article published on 18 January 2008

Isoform switching from SM-B to SM-A myosin results in decreased contractility and altered expression of thin filament regulatory proteins.

scientific article

MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin heavy chain gene expression

scientific journal article

Molecular basis of diastolic dysfunction.

scientific article published on January 2008

Molecular characterization of two myosin heavy chain genes expressed in the adult heart

scientific article published in June 1982

Muscle-specific RNA processing continues in the absence of myogenin expression

scientific article published on November 1990

Myosin heavy chain isoform expression in rat smooth muscle development

scientific article

Myosin heavy chain isoform expression regulates shortening velocity in smooth muscle: studies using an SMB KO mouse line.

scientific article published in January 2004

Myosin isoform expression in developing and remodeling rat lung

scientific article published on 01 June 1993

Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise.

scientific article published on 4 February 2013

Nucleotide sequences of the rabbit alpha-smooth-muscle and beta-non-muscle actin mRNAs

scientific article

Obligatory role of neuronal nitric oxide synthase in the heart's antioxidant adaptation with exercise

scientific article

Overexpression of SERCA2b in the heart leads to an increase in sarcoplasmic reticulum calcium transport function and increased cardiac contractility

scientific article published on 01 August 2000

Overexpression of sarcolipin decreases myocyte contractility and calcium transient

scientific article published on 01 January 2005

Phosphorylation of elk-1 by MEK/ERK pathway is necessary for c-fos gene activation during cardiac myocyte hypertrophy.

scientific article published in August 2000

Phosphorylation-status of phospholamban and calsequestrin modifies their affinity towards commonly used antibodies

scientific article published on 01 September 2004

Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.

scientific article

Probing cationic selectivity of cardiac calsequestrin and its CPVT mutants

scientific article published on 01 April 2011

Protein kinase associated with hnRNP from Hela cell nuclei. Partial purification and properties

scientific article published in January 1979

Reduced SERCA2a converts sub-lethal myocardial injury to infarction and affects postischemic functional recovery.

scientific article published on 12 November 2008

Regulation of myosin heavy-chain gene expression during skeletal-muscle hypertrophy

scientific article published on February 1989

Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development

scientific article published on March 1992

Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart

scientific article published in October 2001

SERCA1a can functionally substitute for SERCA2a in the heart

scientific journal article

SM2(+/-) male mice are predisposed to develop urinary tract obstruction and hyper contractility of the bladder smooth muscle upon ageing

scientific article

SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrum

scientific article published on 7 November 2012

Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology

scientific article published on 01 September 1998

Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity.

scientific article published on 24 February 2015

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals.

scientific article

Sarcolipin overexpression improves muscle energetics and reduces fatigue

scientific article

Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump.

scientific article published on 22 January 2013

Sarcolipin trumps β-adrenergic receptor signaling as the favored mechanism for muscle-based diet-induced thermogenesis.

scientific article published on 10 June 2013

Sarcomeric myosin heavy chain gene family: organization and pattern of expression

scientific article published in June 1986

Sarcoplasmic reticulum Ca(2+) atpase (SERCA) 1a structurally substitutes for SERCA2a in the cardiac sarcoplasmic reticulum and increases cardiac Ca(2+) handling capacity.

scientific article published in July 2001

Sarcoplasmic reticulum Ca2+ ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart

scientific article published on 20 January 2015

Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis

scientific article published in December 2005

Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.

scientific article

Sarcoplasmic reticulum gene expression in pressure overload-induced cardiac hypertrophy in rabbit

scientific article published on 01 January 1995

Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism

scientific article published on October 2017

Skeletal muscle inefficiency protects against obesity

scientific article published on 01 September 2019

Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis.

scientific article published on November 1994

Smooth muscle myosin regulation by serum and cell density in cultured rat lung connective tissue cells

scientific article published on 01 August 1993

Solubilization of membrane proteins for two-dimensional gel electrophoresis: identification of sarcoplasmic reticulum membrane proteins.

scientific article

Somatic gene therapy to treat heart failure is one step closer to reality

scientific article published on 8 April 2009

Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump

scientific article published on 01 June 2001

Strain specific differences in muscle Ca<sup>2+</sup> transport and mitochondrial electron transport proteins between FVB/N and C57BL/6J mice

scientific article published on 02 December 2020

Structural effects in solvolytic reactions; carbon-13 NMR studies of carbocations: Effect of increasing electron demand on the carbon-13 NMR shifts in substituted tert-cumyl and 1-aryl-1-cyclopentyl carbocations-correlation of the data by a new set

scientific article published on 01 December 1980

Structure and organization of the mouse Atp2a2 gene encoding the sarco(endo)plasmic reticulum Ca2+-ATPase 2 (SERCA2) isoforms

scientific article published in February 2000

Targeted overexpression of sarcolipin in the mouse heart decreases sarcoplasmic reticulum calcium transport and cardiac contractility.

scientific article published on 19 December 2005

Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts

scientific journal article

Targeting calcium transport in ischaemic heart disease.

scientific article published on 29 July 2009

The C-terminal calcium-sensitive disordered motifs regulate isoform-specific polymerization characteristics of calsequestrin

scientific article

The calsequestrin mutation CASQ2D307H does not affect protein stability and targeting to the junctional sarcoplasmic reticulum but compromises its dynamic regulation of calcium buffering

scientific journal article

The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice

scientific article published on 25 November 2004

The expression of SR calcium transport ATPase and the Na(+)/Ca(2+)Exchanger are antithetically regulated during mouse cardiac development and in Hypo/hyperthyroidism

scientific article published in March 2000

The prolonged survival of fibroblasts with forced lipid catabolism in visceral fat following encapsulation in alginate-poly-L-lysine.

scientific article published on 09 May 2012

The regulation of calcium cycling in stressed hearts

scientific article published in January 1992

The role of skeletal-muscle-based thermogenic mechanisms in vertebrate endothermy

scientific article

The sarcoplasmic reticulum Ca2+-ATPase (SERCA2) gene promoter activity is decreased in response to severe left ventricular pressure-overload hypertrophy in rat hearts

scientific article published on 01 April 1999

The smooth muscle myosin seven amino acid heavy chain insert's kinetic role in the crossbridge cycle for mouse bladder

scientific journal article

Thyroid hormone receptor modulates the expression of the rabbit cardiac sarco (endo) plasmic reticulum Ca(2+)-ATPase gene.

scientific article published on January 1994

Time course of airway mechanics of the (+)insert myosin isoform knockout mouse.

scientific article published on 4 September 2003

Transcription factor Sp1 regulates SERCA2 gene expression in pressure-overloaded hearts: a study using in vivo direct gene transfer into living myocardium

scientific article published on 01 July 2003

Transgenic mouse models for cardiac dysfunction by a specific gene manipulation.

scientific article

Troponin I gene expression during human cardiac development and in end-stage heart failure

scientific article

Up-regulation of sarcoplasmic reticulum Ca(2+) uptake leads to cardiac hypertrophy, contractile dysfunction and early mortality in mice deficient in CASQ2.

scientific article published on 6 November 2012

cis-4-Hydroxy-L-proline and ethyl-3,4-dihydroxybenzoate prevent myogenesis of C2C12 muscle cells and block MyoD1 and myogenin expression

scientific article published on May 1992

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