List of works - Huige Li

17β-Estradiol reduces nitric oxide production in the Guinea pig cochlea

scientific article

A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase

scientific article published in March 2005

Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice

scientific article (publication date: 2015)

Antioxidant capacity of phenolic compounds on human cell lines as affected by grape-tyrosinase and Botrytis-laccase oxidation.

scientific article

Antioxidant effects of resveratrol in the cardiovascular system.

scientific article

Apolipoprotein E Deficiency Causes Endothelial Dysfunction in the Mouse Retina

scientific article published on 12 November 2019

Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells

scientific article published on 24 March 2014

Ascorbic acid reduces noise-induced nitric oxide production in the guinea pig ear.

scientific article

Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stress

scientific article published on 01 February 2011

Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells.

scientific article published on 13 January 2011

Biopterin metabolism and eNOS expression during hypoxic pulmonary hypertension in mice.

scientific article

Cardiovascular effects and molecular targets of resveratrol.

scientific article published on 04 January 2012

Circadian Rhythm in Adipose Tissue: Novel Antioxidant Target for Metabolic and Cardiovascular Diseases

scientific article published on 09 October 2020

Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice

scientific article published on 2 August 2017

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice

scientific article published on 25 January 2007

Determination of Death in Execution by Lethal Injection in China

scientific article published on 01 July 2018

Dexamethasone lacks effect on blood pressure in mice with a disrupted endothelial NO synthase gene

scientific article published in February 2004

Dexamethasone upregulates Nox1 expression in vascular smooth muscle cells.

scientific article

Dexamethasone, tetrahydrobiopterin and uncoupling of endothelial nitric oxide synthase.

scientific article published in September 2015

Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells

scientific article

Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries

scientific article published on 30 April 2007

Downregulation of BDNF Expression by PKC and by TNF-α in Human Endothelial Cells

scientific article

Doxycycline reduces nitric oxide production in guinea pig inner ears

scientific article published on 26 May 2011

Dual effect of ceramide on human endothelial cells: induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase

scientific article published on October 2002

Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling

scientific journal article

Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice

scientific article published on 20 December 2019

Effects of noise on vascular function, oxidative stress, and inflammation: mechanistic insight from studies in mice.

scientific article published on 17 February 2017

Effects of resveratrol on eNOS in the endothelium and the perivascular adipose tissue

scientific article

Effects of telmisartan or amlodipine monotherapy versus telmisartan/amlodipine combination therapy on vascular dysfunction and oxidative stress in diabetic rats

scientific article published on 27 February 2013

Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles

scientific article published on 29 December 2019

Endothelial dysfunction in tristetraprolin-deficient mice is not caused by enhanced tumor necrosis factor-α expression

scientific article

Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation

scientific article published on 25 July 2016

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Exercise Training and Fasting: Current Insights

scientific article published on 21 January 2020

Expression of NO synthases and redox enzymes in umbilical arteries from newborns born small, appropriate, and large for gestational age.

scientific article published on 19 November 2012

Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells.

scientific article published on 3 May 2004

Gentamicin alters Akt-expression and its activation in the guinea pig cochlea

scientific article published on 31 October 2015

Gentamicin alters nitric oxide production in semicircular canals and otolith organs

scientific article published on 01 October 2010

Gentamicin increases nitric oxide production and induces hearing loss in guinea pigs

scientific article published in August 2008

Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia.

scientific article published on 20 January 2015

Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging.

scientific article

Health Benefits of Fasting and Caloric Restriction.

scientific article published on 23 October 2017

Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates

scientific article published on 31 May 2007

Histamine upregulates gene expression of endothelial nitric oxide synthase in human vascular endothelial cells.

scientific article published on 21 April 2003

Historical development and current status of organ procurement from death-row prisoners in China

scientific article published on 3 December 2015

Human rights violations in organ procurement practice in China

scientific article

Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function

scientific article published on 26 September 2020

Influence of Laccase and Tyrosinase on the Antioxidant Capacity of Selected Phenolic Compounds on Human Cell Lines

scientific article published on 18 September 2015

Influence of mental stress and environmental toxins on circadian clocks: Implications for redox regulation of the heart and cardioprotection

scientific article published on 12 December 2019

Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis

scientific article

Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease

scientific article published on 23 October 2014

Involvement of Gut Microbiota, Microbial Metabolites and Interaction with Polyphenol in Host Immunometabolism

scientific article published on 06 October 2020

Loneliness, Social Isolation, and Cardiovascular Health

scientific article

Maternal treatment of spontaneously hypertensive rats with pentaerythritol tetranitrate reduces blood pressure in female offspring.

scientific article published on 10 November 2014

Midostaurin upregulates eNOS gene expression and preserves eNOS function in the microcirculation of the mouse

scientific article published in June 2005

Molecular mechanisms of the cardiovascular protective effects of polyphenols.

scientific article published on 31 August 2012

Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species-studies in white blood cells and in animal models.

scientific article published on 17 August 2013

Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.

scientific article published on 28 August 2006

New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease ⬇️

scientific article published on 07 January 2019

Nitric oxide in the pathogenesis of vascular disease

scientific article

Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

scientific article published on 08 February 2012

Oxidative Stress: A Unifying Mechanism for Cell Damage Induced by Noise, (Water-Pipe) Smoking, and Emotional Stress-Therapeutic Strategies Targeting Redox Imbalance.

scientific article published on 6 December 2017

Oxidative stress in vascular disease and its pharmacological prevention.

scientific article published on 19 April 2013

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor

scientific article published on 9 February 2018

Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1.

scientific article

Perivascular Adipose Tissue as a Target for Antioxidant Therapy for Cardiovascular Complications

scientific article published on 02 July 2020

Phosphorylation and activation of endothelial nitric oxide synthase by red fruit (Pandanus conoideus Lam) oil and its fractions

scientific article published on 29 December 2019

Physiological mechanisms regulating the expression of endothelial-type NO synthase.

scientific article

Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension

scientific article published in February 2017

Protection of the cochlea by ascorbic acid in noise trauma

scientific article published in April 2009

Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor.

scientific article published on 4 December 2007

Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells.

scientific article

Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells

scientific article published on 11 May 2007

Red wine and cardiovascular health

scientific article published on 6 September 2012

Red wine increases the expression of human endothelial nitric oxide synthase: a mechanism that may contribute to its beneficial cardiovascular effects

scientific article

Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs.

scientific article

Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight

scientific article published on 5 January 2017

Resveratrol and endothelial nitric oxide.

scientific article

Resveratrol and the Interaction between Gut Microbiota and Arterial Remodelling

scientific article published on 01 January 2020

Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

scientific article

Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice.

scientific article published on 7 July 2010

Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase.

scientific article

Resveratrol: a multifunctional compound improving endothelial function. Editorial to: "Resveratrol supplementation gender independently improves endothelial reactivity and suppresses superoxide production in healthy rats" by S. Soylemez et al.

scientific article published on December 2009

Retinal arteriole reactivity in mice lacking the endothelial nitric oxide synthase (eNOS) gene

scientific article published on 01 February 2019

Reversal of endothelial nitric oxide synthase uncoupling and up-regulation of endothelial nitric oxide synthase expression lowers blood pressure in hypertensive rats.

scientific article

Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol.

scientific article published on 10 April 2013

Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice.

scientific article published on 10 July 2014

Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis.

scientific article published on February 2017

Short-Time Ocular Ischemia Induces Vascular Endothelial Dysfunction and Ganglion Cell Loss in the Pig Retina

scientific article published on 21 September 2019

Simultaneous assessment of endothelial function, nitric oxide synthase activity, nitric oxide-mediated signaling, and oxidative stress in individuals with and without hypercholesterolemia

scientific article published on 10 December 2007

Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol

scientific article published on 9 November 2010

T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of ·NO/cGMP Signaling

scientific article published on 18 July 2019

Targeting vascular (endothelial) dysfunction.

scientific article published on 17 May 2016

The M muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice

scientific article published on 26 March 2019

The pharmacology of nitric oxide and nitrates

scientific article published on September 2010

The role of perivascular adipose tissue in obesity-induced vascular dysfunction

scientific article

The roles of gut microbiota and circadian rhythm in the cardiovascular protective effects of polyphenols

scientific article published on 31 October 2019

Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling ⬇️

scientific article published on September 1, 2011

Transcriptional regulation of Nox4 by histone deacetylases in human endothelial cells.

scientific article published on 13 July 2012

Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese Mice.

scientific article published on 19 November 2015

Uncoupling of endothelial NO synthase in atherosclerosis and vascular disease ⬇️

scientific article published on 07 February 2013

Vascular oxidative stress, nitric oxide and atherosclerosis

scientific article published on 09 September 2014

List of works by Huige Li

17β-Estradiol reduces nitric oxide production in the Guinea pig cochlea

A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase

Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice

Antioxidant capacity of phenolic compounds on human cell lines as affected by grape-tyrosinase and Botrytis-laccase oxidation.

Antioxidant effects of resveratrol in the cardiovascular system.

Apolipoprotein E Deficiency Causes Endothelial Dysfunction in the Mouse Retina

Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells

Ascorbic acid reduces noise-induced nitric oxide production in the guinea pig ear.

Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stress

Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells.

Biopterin metabolism and eNOS expression during hypoxic pulmonary hypertension in mice.

Cardiovascular effects and molecular targets of resveratrol.

Circadian Rhythm in Adipose Tissue: Novel Antioxidant Target for Metabolic and Cardiovascular Diseases

Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice

Determination of Death in Execution by Lethal Injection in China

Dexamethasone lacks effect on blood pressure in mice with a disrupted endothelial NO synthase gene

Dexamethasone upregulates Nox1 expression in vascular smooth muscle cells.

Dexamethasone, tetrahydrobiopterin and uncoupling of endothelial nitric oxide synthase.

Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells

Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries

Downregulation of BDNF Expression by PKC and by TNF-α in Human Endothelial Cells

Doxycycline reduces nitric oxide production in guinea pig inner ears

Dual effect of ceramide on human endothelial cells: induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase

Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling

Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice

Effects of noise on vascular function, oxidative stress, and inflammation: mechanistic insight from studies in mice.

Effects of resveratrol on eNOS in the endothelium and the perivascular adipose tissue

Effects of telmisartan or amlodipine monotherapy versus telmisartan/amlodipine combination therapy on vascular dysfunction and oxidative stress in diabetic rats

Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles

Endothelial dysfunction in tristetraprolin-deficient mice is not caused by enhanced tumor necrosis factor-α expression

Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Exercise Training and Fasting: Current Insights

Expression of NO synthases and redox enzymes in umbilical arteries from newborns born small, appropriate, and large for gestational age.

Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells.

Gentamicin alters Akt-expression and its activation in the guinea pig cochlea

Gentamicin alters nitric oxide production in semicircular canals and otolith organs

Gentamicin increases nitric oxide production and induces hearing loss in guinea pigs

Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia.

Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging.

Health Benefits of Fasting and Caloric Restriction.

Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates

Histamine upregulates gene expression of endothelial nitric oxide synthase in human vascular endothelial cells.

Historical development and current status of organ procurement from death-row prisoners in China

Human rights violations in organ procurement practice in China

Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function

Influence of Laccase and Tyrosinase on the Antioxidant Capacity of Selected Phenolic Compounds on Human Cell Lines

Influence of mental stress and environmental toxins on circadian clocks: Implications for redox regulation of the heart and cardioprotection

Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis

Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease

Involvement of Gut Microbiota, Microbial Metabolites and Interaction with Polyphenol in Host Immunometabolism

Loneliness, Social Isolation, and Cardiovascular Health

Maternal treatment of spontaneously hypertensive rats with pentaerythritol tetranitrate reduces blood pressure in female offspring.

Midostaurin upregulates eNOS gene expression and preserves eNOS function in the microcirculation of the mouse

Molecular mechanisms of the cardiovascular protective effects of polyphenols.

Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species-studies in white blood cells and in animal models.

Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.

New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease ⬇️

Nitric oxide in the pathogenesis of vascular disease

Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

Oxidative Stress: A Unifying Mechanism for Cell Damage Induced by Noise, (Water-Pipe) Smoking, and Emotional Stress-Therapeutic Strategies Targeting Redox Imbalance.

Oxidative stress in vascular disease and its pharmacological prevention.

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor

Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1.

Perivascular Adipose Tissue as a Target for Antioxidant Therapy for Cardiovascular Complications

Phosphorylation and activation of endothelial nitric oxide synthase by red fruit (Pandanus conoideus Lam) oil and its fractions

Physiological mechanisms regulating the expression of endothelial-type NO synthase.

Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension

Protection of the cochlea by ascorbic acid in noise trauma

Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor.

Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells.

Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells

Red wine and cardiovascular health

Red wine increases the expression of human endothelial nitric oxide synthase: a mechanism that may contribute to its beneficial cardiovascular effects

Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs.

Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight

Resveratrol and endothelial nitric oxide.

Resveratrol and the Interaction between Gut Microbiota and Arterial Remodelling